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List of works by Markus P Kummer

Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis.

scientific article published in May 2011

Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

scientific article

Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptides (i).

scientific article published on 11 October 2010

Endoplasmic reticulum-localized amyloid beta-peptide is degraded in the cytosol by two distinct degradation pathways

scientific article published in February 2004

Formation of Pmel17 amyloid is regulated by juxtamembrane metalloproteinase cleavage, and the resulting C-terminal fragment is a substrate for gamma-secretase

scientific article published on December 2008

Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease

scientific article published on 30 May 2012

Impact and Therapeutic Potential of PPARs in Alzheimer's Disease

scientific article published on December 2011

Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits

scientific article published on 6 February 2010

Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42.

scientific article

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

scientific article

Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice.

scientific article published on 24 November 2010

Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology

scientific article published on 26 November 2021

Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing

scientific article

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice ⬇️

scientific article published on December 19, 2012

NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits

scientific article published in November 2009

Neuroinflammatory processes in Alzheimer's disease

scientific article published on 15 July 2010

Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation

scientific article published in September 2011

Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice

scientific article published on 8 January 2012

PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models

scientific article

PPARγ/RXRα-induced and CD36-mediated microglial amyloid-β phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.

scientific article published in November 2012

Postoperative ileus involves interleukin-1 receptor signaling in enteric glia

scientific article published on 22 September 2013

Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice

scientific article published on 02 December 2010

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease

scientific article

Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice

scientific article

Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism

scientific article published on 15 September 2008

Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.

scientific article published on 29 April 2013

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

scientific article published on July 2011

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