List of works by Didier Ménard

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

scientific article

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

scientific article

A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants.

scientific article published on 24 April 2018

A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study

scientific article

Absence of K13 Polymorphism in Parasites from Brazilian Endemic Areas

article

Accuracy and reliability of malaria diagnostic techniques for guiding febrile outpatient treatment in malaria-endemic countries

scientific article

Acute undifferentiated febrile illness in rural Cambodia: a 3-year prospective observational study

scientific article published on 22 April 2014

Advantages of an alternative strategy based on consecutive HIV serological tests for detection of HIV antibodies in Central African Republic

scientific article published in August 2003

An innovative tool for moving malaria PCR detection of parasite reservoir into the field

scientific article

An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia

scientific article

Analysis of circulating populations of Plasmodium falciparum in mild and severe malaria in two different epidemiological patterns in Madagascar

scientific article published on 16 September 2008

Antimalarial Drug Resistance: A Threat to Malaria Elimination

scientific article published on 13 March 2017

Antimicrobial resistance among uropathogens that cause community-acquired urinary tract infections in Bangui, Central African Republic

scientific article published in January 2003

Artemisinin resistance in Plasmodium falciparum

scientific article published in June 2014

Artemisinin-Resistant Plasmodium falciparum K13 Mutant Alleles, Thailand-Myanmar Border

scientific article published on August 2016

Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: up-dated baseline data from randomized and multi-site clinical trials

scientific article

Association of failures of seven-day courses of artesunate in a non-immune population in Bangui, Central African Republic with decreased sensitivity of Plasmodium falciparum.

scientific article

Association of microsatellite variations of Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene with reduced in vitro susceptibility to quinine: lack of confirmation in clinical isolates from Africa

scientific article

Challenges in Antimalarial Drug Treatment for Vivax Malaria Control

scientific article

Characterization of P. vivax blood stage transcriptomes from field isolates reveals similarities among infections and complex gene isoforms

scientific article published on 10 August 2017

Chloroquine clinical failures in P. falciparum malaria are associated with mutant Pfmdr-1, not Pfcrt in Madagascar

scientific article

Cocirculation of measles virus genotype B2 and B3.1 in Central African Republic during the 2000 measles epidemic

scientific article published in July 2006

Complexity of Infection and Genetic Diversity in Cambodian Plasmodium vivax

scientific article

Compliance, safety, and effectiveness of fixed-dose artesunate-amodiaquine for presumptive treatment of non-severe malaria in the context of home management of malaria in Madagascar

scientific article published on February 2012

Country-wide assessment of the genetic polymorphism in Plasmodium falciparum and Plasmodium vivax antigens detected with rapid diagnostic tests for malaria

scientific article published on 28 October 2008

De novo assembly of a field isolate genome reveals novel Plasmodium vivax erythrocyte invasion genes ⬇️

scientific article

Dihydrofolate reductase I164L mutation in Plasmodium falciparum, Madagascar

scientific article published in July 2008

Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

scientific article

Drug-resistant malaria in Bangui, Central African Republic: an in vitro assessment

scientific article published on August 2005

Drug-resistant malaria parasites introduced into Madagascar from Comoros Islands

scientific article

Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria

scientific article published on 21 November 2012

Effects of mefloquine use on Plasmodium vivax multidrug resistance

scientific article

Efficacy and Safety of Pyronaridine-Artesunate for Treatment of Uncomplicated Plasmodium falciparum Malaria in Western Cambodia

scientific article published on 29 February 2016

Efficacy of artemisinin-based combination therapies and prevalence of molecular markers associated with artemisinin, piperaquine and sulfadoxine-pyrimethamine resistance in Sierra Leone

scholarly article by Samuel J Smith et al published 19 June 2018 in Acta Tropica

Efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, chloroquine-sulfadoxine-pyrimethamine combination, and amodiaquine-sulfadoxine-pyrimethamine combination in Central African children with noncomplicated malaria.

scientific article published on May 2005

Efficacy of chloroquine-proguanil malaria prophylaxis in a non-immune population in Bangui, Central African Republic: a case-control study.

scientific article published on 28 November 2005

Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010.

scientific article published on 3 December 2012

Efficacy of topical mosquito repellent (picaridin) plus long-lasting insecticidal nets versus long-lasting insecticidal nets alone for control of malaria: a cluster randomised controlled trial

scientific article published on 29 June 2016

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda

scientific article published on 03 August 2020

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa

scientific article published on 22 February 2017

Endoperoxide-based compounds: cross-resistance with artemisinins and selection of a Plasmodium falciparum lineage with a K13 non-synonymous polymorphism.

scientific article published on 21 November 2017

Epidemiological situation of malaria in Madagascar: baseline data for monitoring the impact of malaria control programmes using serological markers

scientific article

Erratum to: An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia

scientific article published on 20 December 2016

Evaluation of rapid HIV testing strategies in under equipped laboratories in the Central African Republic

scientific article published on June 2005

Evaluation of two new immunochromatographic assays for diagnosis of malaria

scientific article published on November 2008

Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment

scientific article published on 26 May 2015

Evolution of the Mycobacteria Laboratory of the Pasteur Institute of Madagascar from 1991 to 1994

scientific article published on January 1995

Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers

scientific article published on 12 August 2013

Extra-pulmonary tuberculosis in Antananarivo. Principal localizations and biological diagnosis

scientific article published on January 1995

Extrapulmonary and pulmonary tuberculosis in antananarivo (madagascar): high clustering rate in female patients

scientific article

Field trial evaluation of the performances of point-of-care tests for screening G6PD deficiency in Cambodia

scientific article

Focused Screening and Treatment (FSAT): a PCR-based strategy to detect malaria parasite carriers and contain drug resistant P. falciparum, Pailin, Cambodia

scientific article

Frequency distribution of antimalarial drug-resistant alleles among isolates of Plasmodium falciparum in Bangui, Central African Republic.

scientific article published on February 2006

G6PD deficiency in Plasmodium falciparum and Plasmodium vivax malaria-infected Cambodian patients

scientific article published on 28 May 2013

G6PD testing in support of treatment and elimination of malaria: recommendations for evaluation of G6PD tests

scientific article published on 4 November 2013

Genetic diversity and genotype multiplicity of Plasmodium falciparum infections in symptomatic individuals living in Bangui (CAR).

scientific article published on 18 April 2008

Genetic diversity and population structure of Plasmodium vivax isolates from Sudan, Madagascar, French Guiana and Armenia

scientific article published on 4 August 2014

Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion ⬇️

scientific article published on 22 October 2018

Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: impact on vaccine design for placental malaria

scientific article

Genomic analyses of complex P. vivax infections

scientific article published on 22 September 2014

Geographical patterns of malaria transmission based on serological markers for falciparum and vivax malaria in Ratanakiri, Cambodia

scientific article published on 19 October 2016

Global analysis of Plasmodium falciparum Na(+)/H(+) exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine

scientific article

Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests

scientific article published on 17 May 2010

HIV epidemic in Central African Republic: high prevalence rates in both rural and urban areas

scientific article published on March 2004

Heritability of the human infectious reservoir of malaria parasites

scientific article

High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana.

scientific article published in July 2009

High proportion of multiple copies of Plasmodium falciparum Plasmepsin-2 gene in African isolates: Is piperaquine resistance emerging in Africa?

article

High-throughput analysis of antimalarial susceptibility data by the worldwide antimalarial resistance network (WWARN) In Vitro analysis and reporting tool

scientific article

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

scientific article

History and current status of Plasmodium falciparum antimalarial drug resistance in Madagascar

scientific article published on January 2010

Identification and Characterization of Two Novel RNA Viruses from Anopheles gambiae Species Complex Mosquitoes

scientific article

Immunohematological reference ranges for adults from the Central African Republic

scientific article

Implementation and application of a multiplex assay to detect malaria-specific antibodies: a promising tool for assessing malaria transmission in Southeast Asian pre-elimination areas

scientific article

Importance of household-level risk factors in explaining micro-epidemiology of asymptomatic malaria infections in Ratanakiri Province, Cambodia

scientific article published in Scientific Reports

Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp

scientific article published on 23 August 2019

In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound

scientific article

In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparum

scientific article

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia

scientific article

Individual Plasmodium vivax msp1 variants within polyclonal P. vivax infections display different propensities for relapse

scientific article published on 11 January 2012

Injections, cocktails and diviners: therapeutic flexibility in the context of malaria elimination and drug resistance in Northeast Cambodia

scientific article (publication date: 2013)

K13-Propeller Polymorphisms in Plasmodium falciparum Isolates from Patients in Mayotte in 2013 and 2014

scientific article

Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012-2013

scientific article

Low-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola

scientific article (publication date: 7 June 2016)

Malaria PCR detection in Cambodian low-transmission settings: dried blood spots versus venous blood samples

scientific article

Malaria rapid diagnostic test as point-of-care test: study protocol for evaluating the VIKIA Malaria Ag Pf/Pan

scientific article

Management of uncomplicated malaria in febrile under five-year-old children by community health workers in Madagascar: reliability of malaria rapid diagnostic tests

scientific article published on 25 March 2012

Mapping the aetiology of non-malarial febrile illness in Southeast Asia through a systematic review--terra incognita impairing treatment policies

scientific article (publication date: 2012)

Modelling primaquine-induced haemolysis in G6PD deficiency

scientific article published on 03 February 2017

Molecular epidemiology of wild poliovirus type 1 circulation in West and Central Africa, from 1997 to 1999, using genotyping with a restriction fragment length polymorphism assay.

scientific article published on 4 December 2007

Molecular surveillance for artemisinin resistance in Africa

scientific article published on August 2014

Multiple and successive treatment failures in a patient infected by Plasmodium falciparum in Cambodia and treated by dihydroartemisinin-piperaquine

scientific article published on 6 April 2016

Multiple independent introductions of Plasmodium falciparum in South America

scientific article

National Malaria Prevalence in Cambodia: Microscopy Versus Polymerase Chain Reaction Estimates

scientific article published on 11 July 2016

Novel Cross-Border Approaches to Optimise Identification of Asymptomatic and Artemisinin-Resistant Plasmodium Infection in Mobile Populations Crossing Cambodian Borders

scientific article published on 9 September 2015

Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies

scientific article published on 11 September 2013

OPV strains circulation in HIV infected infants after National Immunisation Days in Bangui, Central African Republic

scientific article

Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia

scientific article

Origins of the recent emergence of Plasmodium falciparum pyrimethamine resistance alleles in Madagascar

scientific article

Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World

scientific article published in April 2014

Performance and reliability of the SYBR Green I based assay for the routine monitoring of susceptibility of Plasmodium falciparum clinical isolates

scientific article published on 5 March 2008

Performance of "VIKIA Malaria Ag Pf/Pan" (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections

scientific article

Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis

scientific article published on 13 December 2019

Performance of the CareStart™ G6PD deficiency screening test, a point-of-care diagnostic for primaquine therapy screening

scientific article

Plasmepsin II-III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum.

scientific article published on 2 May 2018

Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes

scientific article

Plasmodium falciparum Na+/H+ Exchanger (pfnhe-1) Genetic Polymorphism in Indian Ocean Malaria-Endemic Areas

scientific article (publication date: 2013)

Plasmodium falciparum Resistance to Artemisinin Derivatives and Piperaquine: A Major Challenge for Malaria Elimination in Cambodia

scientific article

Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations

scientific article published on 22 December 2015

Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility

scientific article published on 24 August 2009

Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro

scientific article

Plasmodium falciparum parasite population structure and gene flow associated to anti-malarial drugs resistance in Cambodia

scientific article published on 14 June 2016

Plasmodium falciparum susceptibility to antimalarial drugs: global data issued from the Pasteur Institutes international network

scientific article

Plasmodium knowlesi Infection in Humans, Cambodia, 2007–2010

scientific article (publication date: October 2011)

Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study

scientific article

Plasmodium vivax Diversity and Population Structure across Four Continents

scientific article published in 2015

Plasmodium vivax Malaria in Cambodia

scientific article published on 05 October 2016

Plasmodium vivax and the Duffy antigen: a paradigm revisited

scientific article published on 23 July 2010

Plasmodium vivax clinical malaria is commonly observed in Duffy-negative Malagasy people

scientific article

Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine

scientific article

Plasmodium vivax mdr1 genotypes in isolates from successfully cured patients living in endemic and non-endemic Brazilian areas

scientific article published on 18 February 2016

Plasmodium vivax multidrug resistance-1 gene polymorphism in French Guiana

scientific article

Plasmodium vivax resistance to chloroquine in Madagascar: clinical efficacy and polymorphisms in pvmdr1 and pvcrt-o genes

scientific article published on 22 September 2008

Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes

scientific article published in Nature Communications

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

scientific article

Polymorphisms in pfcrt, pfmdr1, dhfr genes and in vitro responses to antimalarials in Plasmodium falciparum isolates from Bangui, Central African Republic.

scientific article published on September 2006

Prevalence of Mycobacterium bovis in human pulmonary and extra-pulmonary tuberculosis in Madagascar

scientific article published on July 1999

Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

scientific article published on 14 May 2020

Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar

scientific article published on 22 May 2007

Rapid detection of point mutations in Plasmodium falciparum genes associated with antimalarial drugs resistance by using High-Resolution Melting analysis

scientific article published on 22 May 2009

Reactive case-detection of malaria in Pailin Province, Western Cambodia: lessons from a year-long evaluation in a pre-elimination setting

scientific article published on March 2016

Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia

scientific article published on 3 December 2012

Reduced impact of pyrimethamine drug pressure on Plasmodium malariae dihydrofolate reductase gene

scientific article published on 28 November 2011

Reduced polymorphism in the Kelch propeller domain in Plasmodium vivax isolates from Cambodia

scientific article

Resistance of Plasmodium falciparum to antimalarial drugs: impact on malaria pre-elimination in Madagascar

scientific article published on June 2011

Results of active surveillance of acute flaccid paralysis in the Central African Republic and Chad from 1995 to 2000

scientific article published on January 2002

Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: a workshop report

scientific article

Role of K13 Mutations in Artemisinin-Based Combination Therapy

scientific article published on 22 September 2016

Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites

scientific article published on 17 December 2007

Serological markers to measure recent changes in malaria at population level in Cambodia

scientific article

Short report: prevalence and chloroquine sensitivity of Plasmodium malariae in Madagascar.

scientific article

Spatial clustering and risk factors of malaria infections in Ratanakiri Province, Cambodia

scientific article

Study of 3985 female genital smears from the Clinical Biology Center of the Pasteur Institute in Madagascar

scientific article published on January 1994

Targeting a Reticulocyte Binding Protein and Duffy Binding Protein to Inhibit Reticulocyte Invasion by Plasmodium vivax. ⬇️

scientific article published on 12 July 2018

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data

scientific article published on 31 March 2015

The evolutionary history of Plasmodium vivax as inferred from mitochondrial genomes: parasite genetic diversity in the Americas

scientific article published on 02 June 2013

The global distribution of the Duffy blood group

scientific article

The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study

scientific article

Therapeutic efficacy of fixed dose artesunate-mefloquine for the treatment of acute, uncomplicated Plasmodium falciparum malaria in Kampong Speu, Cambodia

scientific article published on 23 September 2013

Tolerability and safety of weekly primaquine against relapse of Plasmodium vivax in Cambodians with glucose-6-phosphate dehydrogenase deficiency

scientific article published on 25 August 2015

Towards a better understanding of the molecular mechanisms of P. falciparum resistance to artemisinin

scientific article published in August 2014

Towards real-time monitoring of artemisinin resistance

scientific article published on 20 February 2015

Transmission of tuberculosis in the prison of Antananarivo (Madagascar).

scientific article published on November 2000

Treatment Failure of Dihydroartemisinin/Piperaquine for Plasmodium falciparum Malaria, Vietnam

scientific article published on April 2017

Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay

scientific article published on 4 June 2015

Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children

scientific article

Which malaria rapid test for Madagascar? Field and laboratory evaluation of three tests and expert microscopy of samples from suspected malaria patients in Madagascar

scientific article published on March 2007

Whole genome sequencing of field isolates provides robust characterization of genetic diversity in Plasmodium vivax

scientific article

Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains

scientific article

Wild poliovirus type 1, Central African Republic

scientific article published on September 2005

[Immunoblot applied to the diagnosis of congenital toxoplasmosis]

scientific article published on 01 October 1999

[Toxoplasmosis, rubella, syphilis, hepatitis B and HIV infection in women being followed for pregnancy in a population on the east coast of New Caledonia ]

scientific article published in December 2001

Paulina is supported by:

About Paulina

Help