List of works - Takashi Hirasawa

13 C-metabolic flux analysis in heterologous cellulase production by Bacillus subtilis genome-reduced strain.

scientific article published on 22 March 2014

A Corynebacterium glutamicum rnhA recG double mutant showing lysozyme-sensitivity, temperature-sensitive growth, and UV-sensitivity

scientific article

A mutation in the Corynebacterium glutamicum ltsA gene causes susceptibility to lysozyme, temperature-sensitive growth, and L-glutamate production.

scientific article published on May 2000

Adaptation of Saccharomyces cerevisiae cells to high ethanol concentration and changes in fatty acid composition of membrane and cell size

scientific article

Analysis of adaptation to high ethanol concentration in Saccharomyces cerevisiae using DNA microarray

scientific article published on 6 January 2009

Characterization of a Corynebacterium glutamicum dnaB mutant that shows temperature-sensitive growth and mini-cell formation

scientific article published on 21 August 2014

Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray

scientific article

Comparison of transcriptional responses to osmotic stresses induced by NaCl and sorbitol additions in Saccharomyces cerevisiae using DNA microarray

scientific article published in December 2006

Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae

scientific article published on 13 November 2008

Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae

scientific article

Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum

scientific article published on 3 August 2009

Differential importance of trehalose accumulation in Saccharomyces cerevisiae in response to various environmental stresses

scientific article published on 29 September 2009

Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum

scientific article published in July 2008

Dynamic change in promoter activation during lysine biosynthesis in Escherichia coli cells

scientific article published on 28 November 2007

Effect of malic enzyme on ethanol production by Synechocystis sp. PCC 6803.

scientific article

Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum

scientific article

Effect of trehalose accumulation on response to saline stress in Saccharomyces cerevisiae

scientific article published in January 2009

Effectiveness of the Bacillus subtilis genome-reduced strain as an ethanol production host

scientific article published in 2022

Enhanced L-cysteine production by overexpressing potential L-cysteine exporter genes in an L-cysteine-producing recombinant strain of Corynebacterium glutamicum

scientific article published on 06 September 2019

Enhanced acetic acid and succinic acid production under microaerobic conditions by Corynebacterium glutamicum harboring Escherichia coli transhydrogenase gene pntAB.

scientific article published in January 2014

Enhanced dipicolinic acid production during the stationary phase in Bacillus subtilis by blocking acetoin synthesis

scientific article published on 29 June 2015

Enhancement of 1,5-diaminopentane production in a recombinant strain of Corynebacterium glutamicum by Tween 40 addition

scientific article published in January 2016

Extracting the hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA microarray data using the self-organizing map: biosynthesis of amino acids

scientific article

Fluorescent phospholipid analogs as microscopic probes for detection of the mycolic acid-containing layer in Corynebacterium glutamicum: detecting alterations in the mycolic acid-containing layer following ethambutol treatment

scientific article published in November 2005

Genome-wide analysis of the effects of location and number of stress response elements on gene expression in Saccharomyces cerevisiae

scientific article published on 01 November 2008

Genome-wide expression analysis of Saccharomyces pastorianus orthologous genes using oligonucleotide microarrays

scientific article

Genome-wide identification of the targets for genetic manipulation to improve L-lactate production by Saccharomyces cerevisiae by using a single-gene deletion strain collection

scientific article published on 9 May 2013

Identification of target genes conferring ethanol stress tolerance to Saccharomyces cerevisiae based on DNA microarray data analysis

scientific article

Improvement of L-lactate production by CYB2 gene disruption in a recombinant Saccharomyces cerevisiae strain under low pH condition

scientific article

Improving protein secretion of a transglutaminase-secreting Corynebacterium glutamicum recombinant strain on the basis of 13C metabolic flux analysis

scientific article published on 08 September 2011

Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli

scientific article

Integrated Analysis of the Transcriptome and Metabolome of Corynebacterium glutamicum during Penicillin-Induced Glutamic Acid Production

scientific article published on 11 January 2018

Integrated metabolic flux and omics analysis of Synechocystis sp. PCC 6803 under mixotrophic and photoheterotrophic conditions

scientific article published on 26 June 2014

Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions

scientific article published on 11 April 2013

Investigating the effectiveness of DNA microarray analysis for identifying the genes involved in l-lactate production by Saccharomyces cerevisiae

scientific article published in October 2009

Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using (13)C metabolic flux analysis

scientific article published on 21 June 2012

Investigation of phosphorylation status of OdhI protein during penicillin- and Tween 40-triggered glutamate overproduction by Corynebacterium glutamicum

scientific article published on 19 April 2011

L-Cysteine production by metabolically engineered Corynebacterium glutamicum

scientific article published on 07 February 2019

L-Glutamate production by lysozyme-sensitive Corynebacterium glutamicum ltsAmutant strains ⬇️

scientific article published on October 16, 2001

Metabolic engineering of Saccharomyces cerevisiae to improve succinic acid production based on metabolic profiling

scientific article published on 14 April 2014

Molecular mechanisms and metabolic engineering of glutamate overproduction in Corynebacterium glutamicum

scientific article published on January 2012

Phenotypic convergence in bacterial adaptive evolution to ethanol stress

scientific article published on 3 September 2015

Potential of a Saccharomyces cerevisiae recombinant strain lacking ethanol and glycerol biosynthesis pathways in efficient anaerobic bioproduction.

scientific article published on 26 September 2013

Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803

scientific article published on 01 September 2011

Relationship between noise characteristics in protein expressions and regulatory structures of amino acid biosynthesis pathways

scientific article published in January 2010

Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum

scientific article published on 3 December 2009

Saccharomyces cerevisiae and DNA microarray analyses: what did we learn from it for a better understanding and exploitation of yeast biotechnology?

scientific article published on 23 April 2010

Stable disruption of ethanol production by deletion of the genes encoding alcohol dehydrogenase isozymes in Saccharomyces cerevisiae

scientific article published on 26 October 2011

Systems metabolic engineering: the creation of microbial cell factories by rational metabolic design and evolution

scientific article published on January 2013

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress

scientific article

Understanding the mechanism of heat stress tolerance caused by high trehalose accumulation in Saccharomyces cerevisiae using DNA microarray

scientific article published on 04 January 2012

Utilization of Saccharomyces cerevisiae recombinant strain incapable of both ethanol and glycerol biosynthesis for anaerobic bioproduction

scientific article published on 26 February 2013

fcsA29 mutation is an allele of polA gene of Escherichia coli

scientific article published on 01 February 1999

List of works by Takashi Hirasawa

13 C-metabolic flux analysis in heterologous cellulase production by Bacillus subtilis genome-reduced strain.

A Corynebacterium glutamicum rnhA recG double mutant showing lysozyme-sensitivity, temperature-sensitive growth, and UV-sensitivity

A mutation in the Corynebacterium glutamicum ltsA gene causes susceptibility to lysozyme, temperature-sensitive growth, and L-glutamate production.

Adaptation of Saccharomyces cerevisiae cells to high ethanol concentration and changes in fatty acid composition of membrane and cell size

Analysis of adaptation to high ethanol concentration in Saccharomyces cerevisiae using DNA microarray

Characterization of a Corynebacterium glutamicum dnaB mutant that shows temperature-sensitive growth and mini-cell formation

Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray

Comparison of transcriptional responses to osmotic stresses induced by NaCl and sorbitol additions in Saccharomyces cerevisiae using DNA microarray

Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae

Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae

Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum

Differential importance of trehalose accumulation in Saccharomyces cerevisiae in response to various environmental stresses

Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum

Dynamic change in promoter activation during lysine biosynthesis in Escherichia coli cells

Effect of malic enzyme on ethanol production by Synechocystis sp. PCC 6803.

Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum

Effect of trehalose accumulation on response to saline stress in Saccharomyces cerevisiae

Effectiveness of the Bacillus subtilis genome-reduced strain as an ethanol production host

Enhanced L-cysteine production by overexpressing potential L-cysteine exporter genes in an L-cysteine-producing recombinant strain of Corynebacterium glutamicum

Enhanced acetic acid and succinic acid production under microaerobic conditions by Corynebacterium glutamicum harboring Escherichia coli transhydrogenase gene pntAB.

Enhanced dipicolinic acid production during the stationary phase in Bacillus subtilis by blocking acetoin synthesis

Enhancement of 1,5-diaminopentane production in a recombinant strain of Corynebacterium glutamicum by Tween 40 addition

Extracting the hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA microarray data using the self-organizing map: biosynthesis of amino acids

Fluorescent phospholipid analogs as microscopic probes for detection of the mycolic acid-containing layer in Corynebacterium glutamicum: detecting alterations in the mycolic acid-containing layer following ethambutol treatment

Genome-wide analysis of the effects of location and number of stress response elements on gene expression in Saccharomyces cerevisiae

Genome-wide expression analysis of Saccharomyces pastorianus orthologous genes using oligonucleotide microarrays

Genome-wide identification of the targets for genetic manipulation to improve L-lactate production by Saccharomyces cerevisiae by using a single-gene deletion strain collection

Identification of target genes conferring ethanol stress tolerance to Saccharomyces cerevisiae based on DNA microarray data analysis

Improvement of L-lactate production by CYB2 gene disruption in a recombinant Saccharomyces cerevisiae strain under low pH condition

Improving protein secretion of a transglutaminase-secreting Corynebacterium glutamicum recombinant strain on the basis of 13C metabolic flux analysis

Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli

Integrated Analysis of the Transcriptome and Metabolome of Corynebacterium glutamicum during Penicillin-Induced Glutamic Acid Production

Integrated metabolic flux and omics analysis of Synechocystis sp. PCC 6803 under mixotrophic and photoheterotrophic conditions

Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions

Investigating the effectiveness of DNA microarray analysis for identifying the genes involved in l-lactate production by Saccharomyces cerevisiae

Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using (13)C metabolic flux analysis

Investigation of phosphorylation status of OdhI protein during penicillin- and Tween 40-triggered glutamate overproduction by Corynebacterium glutamicum

L-Cysteine production by metabolically engineered Corynebacterium glutamicum

L-Glutamate production by lysozyme-sensitive Corynebacterium glutamicum ltsAmutant strains ⬇️

Metabolic engineering of Saccharomyces cerevisiae to improve succinic acid production based on metabolic profiling

Molecular mechanisms and metabolic engineering of glutamate overproduction in Corynebacterium glutamicum

Phenotypic convergence in bacterial adaptive evolution to ethanol stress

Potential of a Saccharomyces cerevisiae recombinant strain lacking ethanol and glycerol biosynthesis pathways in efficient anaerobic bioproduction.

Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803

Relationship between noise characteristics in protein expressions and regulatory structures of amino acid biosynthesis pathways

Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum

Saccharomyces cerevisiae and DNA microarray analyses: what did we learn from it for a better understanding and exploitation of yeast biotechnology?

Stable disruption of ethanol production by deletion of the genes encoding alcohol dehydrogenase isozymes in Saccharomyces cerevisiae

Systems metabolic engineering: the creation of microbial cell factories by rational metabolic design and evolution

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress

Understanding the mechanism of heat stress tolerance caused by high trehalose accumulation in Saccharomyces cerevisiae using DNA microarray

Utilization of Saccharomyces cerevisiae recombinant strain incapable of both ethanol and glycerol biosynthesis for anaerobic bioproduction

fcsA29 mutation is an allele of polA gene of Escherichia coli