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List of works by Yasuhiko Igawa

1000 INTRINSIC PEPTIDES MEDIATES ADIPOSE TISSUE-DERIVED STEM CELL-INDUCED RESTORATION OF ERECTILE FUNCTION IN DIABETES RATS

scientific article published on 04 April 2012

A new Ehlers-Danlos syndrome with craniofacial characteristics, multiple congenital contractures, progressive joint and skin laxity, and multisystem fragility-related manifestations.

scientific article

A survey on clinical practice of interstitial cystitis in Japan

scientific article

Adjuvant chemotherapy is possibly beneficial for locally advanced or node-positive bladder cancer

scientific article published on 6 November 2014

Age-related changes in function and gene expression of the male and female mouse bladder.

scientific article published in February 2018

Aggressive Cancer Behavior of Latent Gleason Pattern 5 in Prostatectomy Specimens

scientific article published on 01 November 2018

Alveolar soft-part sarcoma of the retroperitoneum

scientific article published in October 2006

Annular rectal constriction due to infiltration by bladder cancer

scientific article published on 01 July 2006

Are neuroendocrine cells responsible for the development of benign prostatic hyperplasia?

scientific article published on 01 August 2002

Association between lower urinary tract symptoms and sexual dysfunction assessed using the core lower urinary tract symptom score and International Index of Erectile Function-5 questionnaires

scientific article published on 30 January 2012

Attenuated lipopolysaccharide-induced inflammatory bladder hypersensitivity in mice deficient of transient receptor potential ankilin1

scientific article published in Scientific Reports

Autologous bone-marrow-derived mesenchymal stem cell transplantation into injured rat urethral sphincter

scientific article published on 25 February 2010

Benefit of adjuvant immunotherapy in renal cell carcinoma: A myth or a reality?

scientific article

Beta3-Adrenoceptor Agonists: Possible Role in the Treatment of Overactive Bladder ⬇️

scientific article published on December 21, 2010

Botulinum toxin type A injection for refractory interstitial cystitis: A randomized comparative study and predictors of treatment response

scientific article published on 2 June 2015

CXCR3 binding chemokine and TNFSF14 over expression in bladder urothelium of patients with ulcerative interstitial cystitis

scientific article published on 22 January 2010

Calponin h1 expression in renal tumor vessels: correlations with multiple pathological factors of renal cell carcinoma

scientific article published in March 2004

Cardiovascular safety of antimuscarinic add-on therapy in patients with overactive bladder who had a suboptimal response to mirabegron monotherapy: A post hoc analysis from the Japanese MILAI II study

scientific article published on 30 September 2019

Catheterization: possible complications and their prevention and treatment

scientific article published on 22 April 2008

Cessation of long-term adjuvant androgen deprivation therapy after radical prostatectomy: is it feasible?

scientific article published on 12 September 2016

Changes in the function and expression of T-type and N-type calcium channels in the rat bladder after bladder outlet obstruction

scientific article published on 9 October 2013

Characteristics of Lower Urinary Tract Dysfunction and Bladder Afferent Nerve Properties in Type 2 Diabetic Goto-Kakizaki Rats ⬇️

scientific article published on October 24, 2012

Characteristics of the mechanosensitive bladder afferent activities in relation with microcontractions in male rats with bladder outlet obstruction.

scientific article

Characterization of beta-adrenoceptor subtype in bladder smooth muscle in cynomolgus monkey

scientific article published in January 2002

Clinical characterization of interstitial cystitis/bladder pain syndrome in women based on the presence or absence of Hunner lesions and glomerulations

scientific article published on 23 August 2020

Clinical guideline for male lower urinary tract symptoms

scientific article published in October 2009

Clinical guidelines for overactive bladder

scientific article published in February 2009

Clinical guidelines for the diagnosis and treatment of lower urinary tract dysfunction in patients with spinal cord injury

scientific article published on 19 February 2020

Clinical significance of random bladder biopsy in primary T1 bladder cancer.

scientific article published on 8 March 2018

Combination of docetaxel, ifosfamide and cisplatin (DIP) as a potential salvage chemotherapy for metastatic urothelial carcinoma

scientific article

Comparison of the effects of oestrogen deficiency and old age on primary bladder afferent activity and voiding behaviour in the ageing female rat ⬇️

scientific article published on September 28, 2010

Continent urinary reservoir formation with transverse colon for patients with pelvic irradiation

scientific article published on 01 April 2002

Cystometric findings in mice lacking muscarinic M2 or M3 receptors

scientific article published in December 2004

Defining overactive bladder as hypersensitivity

scientific article published on October 2007

Detrusor underactivity: Pathophysiological considerations, models and proposals for future research. ICI-RS 2013.

scientific article

Diagnostic value of urinary CXCL10 as a biomarker for predicting Hunner type interstitial cystitis.

scientific article

Differential roles of peripheral and spinal endothelin receptors in the micturition reflex in rats

scientific article published in October 2004

Differentiation of smooth muscle cells from human amniotic mesenchymal cells implanted in the freeze-injured mouse urinary bladder

scientific article published on 05 January 2010

Digital quantitative analysis of mast cell infiltration in interstitial cystitis.

scientific article published on 24 October 2017

Direct influence of systemic desensitization by resiniferatoxin on the activities of Aδ- and C-fibers in the rat primary bladder mechanosensitive afferent nerves

scientific article published on 10 August 2016

Dopaminergic mechanisms controlling urethral function in rats

scientific article published in January 2006

EXCISION OF GIANT PELVIC LIPOSARCOMA NECESSITATING FEMORAL-FEMORAL ARTERY BYPASS AND GAUZE PACKING FOR ILIAC ARTERY INVOLVEMENT AND MASSIVE PRE-SACRAL BLEEDING-A CASE REPORT

scientific article published on 01 January 2016

Effect of cerebrospinal fluid shunt surgery on lower urinary tract dysfunction in idiopathic normal pressure hydrocephalus

scientific article published on 11 September 2017

Effects of CL316,243, a beta 3-adrenoceptor agonist, and intravesical prostaglandin E2 on the primary bladder afferent activity of the rat.

scientific article published in June 2010

Effects of L-arginine, mirabegron, and oxybutynin on the primary bladder afferent nerve activities synchronized with reflexic, rhythmic bladder contractions in the rat.

scientific article published on 14 February 2014

Effects of Nitric Oxide on the Primary Bladder Afferent Activities of the Rat With and Without Intravesical Acrolein Treatment ⬇️

scientific article published on October 26, 2010

Effects of Sildenafil, a Phosphodiesterase Type 5 Inhibitor, on the Primary Single Afferent Activity of the Rat Bladder

scientific article published on 19 March 2015

Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat.

scientific article published on 28 October 2011

Effects of beta(3)-adrenoceptor stimulation on prostaglandin E(2)-induced bladder hyperactivity and on the cardiovascular system in conscious rats

scientific article published in January 2002

Effects of intravesical instillation of ATP on rat bladder primary afferent activity and its relationship with capsaicin‐sensitivity ⬇️

scientific article published on July 21, 2010

Effects of mirabegron, a novel β3-adrenoceptor agonist, on primary bladder afferent activity and bladder microcontractions in rats compared with the effects of oxybutynin

scientific article published on 5 September 2012

Effects of natriuretic peptides on intracavernous pressure and blood pressure in conscious rats

scientific article published in July 2008

Effects of resiniferatoxin desensitization of capsaicin-sensitive afferents on detrusor over-activity induced by intravesical capsaicin, acetic acid or ATP in conscious rats ⬇️

scientific article published on April 17, 2003

Effects of selective beta2 and beta3-adrenoceptor agonists on detrusor hyperreflexia in conscious cerebral infarcted rats

scientific article published in September 2002

Efficacy and Safety of the Selective β3 -Adrenoceptor Agonist Mirabegron in Japanese Patients with Overactive Bladder: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study

scientific article published on 11 March 2014

Efficacy of post-nephroureterectomy cisplatin-based adjuvant chemotherapy for locally advanced upper tract urothelial carcinoma: a multi-institutional retrospective study

scientific article

Elimination of rat spinal neurons expressing neurokinin 1 receptors reduces bladder overactivity and spinal c-fos expression induced by bladder irritation

scientific article published in March 2005

Extent of Hunner lesions: The relationships with symptom severity and clinical parameters in Hunner type interstitial cystitis patients

scientific article published on 9 January 2018

Fate of tetraplegic patients managed by ileal conduit for urinary control: long-term follow-up

scientific article published on 01 May 2002

Feasibility of approximate measurement of bladder volume in male patients using the Lilium α-200 portable ultrasound bladder scanner

scientific article published on 10 March 2019

Functional characterization of beta-adrenoceptor subtypes in the canine and rat lower urinary tract

scientific article

Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322.

scientific article published on 29 May 2012

Functional role of the transient receptor potential melastatin 8 (TRPM8) ion channel in the urinary bladder assessed by conscious cystometry and ex vivo measurements of single-unit mechanosensitive bladder afferent activities in the rat.

scientific article published on 18 July 2015

Functional roles of bladder α1-adrenoceptors in the activation of single-unit primary bladder afferent activity in rats

scientific article published on 31 August 2015

Gains in health utility associated with urinary catheter innovations

article

Genital abnormalities in Pallister-Hall syndrome: Report of two patients and review of the literature

scientific article

Hunner-Type (Classic) Interstitial Cystitis: A Distinct Inflammatory Disorder Characterized by Pancystitis, with Frequent Expansion of Clonal B-Cells and Epithelial Denudation

scientific article published on 20 November 2015

Hydrodistension with or without fulguration of hunner lesions for interstitial cystitis: Long-term outcomes and prognostic predictors

scientific article published on 24 July 2015

Immune-related adverse events predict the therapeutic efficacy of pembrolizumab in urothelial cancer patients

scientific article published on 10 June 2019

Immunoneutralization of nerve growth factor in lumbosacral spinal cord reduces bladder hyperreflexia in spinal cord injured rats

scientific article published on 01 November 2002

Implanted mouse bone marrow-derived cells reconstruct layered smooth muscle structures in injured urinary bladders

scientific article published in January 2008

Improvement of polyuria, bladder sensation and bladder capacity following renal transplantation

scientific article published on 01 May 2006

Improvement of symptoms of aging in males by a preparation LEOPIN ROYAL containing aged garlic extract and other five of natural medicines - comparison with traditional herbal medicines (Kampo).

scientific article published in June 2014

Incidence and risk factors of inguinal hernia after robot-assisted radical prostatectomy

scientific article published on 16 March 2017

Incontinence: How do β3-adrenoceptor agonists work in the bladder?

scientific article published on 21 March 2017

Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis.

scientific article published on 24 June 2016

Increased mRNA Expression of Genes Involved in Pronociceptive Inflammatory Reactions in Bladder Tissue of Interstitial Cystitis ⬇️

scientific article published on May 28, 2013

Individually tailored ultrasound-assisted prompted voiding for institutionalized older adults with urinary incontinence

scientific article published on 21 July 2014

Influence of High Fat Diet Feeding for 20 Weeks on Lower Urinary Tract Function in Mice

scientific article published on 21 September 2012

Influence of urethane-anesthesia on the effect of resiniferatoxin treatment on bladder function in rats with spinal cord injury

scientific article published on 28 December 2013

Inhibition of peripheral FAAH depresses activities of bladder mechanosensitive nerve fibers of the rat.

scientific article published on 16 April 2014

Inhibitory effects of phosphodiesterase 5 inhibitor, tadalafil, on mechanosensitive bladder afferent nerve activities of the rat, and on acrolein‐induced hyperactivity of these nerves ⬇️

scientific article published on May 16, 2012

Inhibitory effects of retigabine, a Kv7 channel activator, on mechanosensitive primary bladder afferent activities and nociceptive behaviors in rats

scientific article

Inhibitory effects of silodosin on the bladder mechanosensitive afferent activities and their relation with bladder myogenic contractions in male rats with bladder outlet obstruction

scientific article published on 06 March 2018

KPR-2579, a novel TRPM8 antagonist, inhibits acetic acid-induced bladder afferent hyperactivity in rats

scientific article published on 21 February 2018

KPR-5714, a Novel Transient Receptor Potential Melastatin 8 (TRPM8) Antagonist, Improves Overactive Bladder via Inhibition of Bladder Afferent Hyperactivity in Rats

scientific article published on 26 February 2020

Lacking transient receptor potential melastatin 2 attenuates lipopolysaccharide-induced bladder inflammation and its associated hypersensitivity in mice

scientific article published on 07 October 2020

Leukopenia as a risk factor for osteonecrosis of the jaw in metastatic prostate cancer treated using zoledronic acid and docetaxel

scientific article published on 11 May 2012

Long-term caloric restriction in rats may prevent age related impairment of in vitro bladder function

scientific article published on 11 November 2014

Long-term safety and efficacy of antimuscarinic add-on therapy in patients with overactive bladder who had a suboptimal response to mirabegron monotherapy: A multicenter, randomized study in Japan (MILAI II study)

scientific article published on 13 December 2018

Longitudinal change of comprehensive lower urinary tract symptoms and various types of urinary incontinence during robot-assisted radical prostatectomy

scientific article published on 14 March 2019

May perioperative ultrasound-guided pelvic floor muscle training promote early recovery of urinary continence after robot-assisted radical prostatectomy?

scientific article published on 30 October 2018

Mechanisms of Pelvic Organ Cross-Talk: 2. Impact of Colorectal Distention on Afferent Nerve Activity of the Rat Bladder ⬇️

scientific article published on March 28, 2013

Mechanosensitive primary bladder afferent activity in rats with and without spinal cord transection

scientific article published on 17 September 2009

Midurethral autologous fascial sling surgery with reconstruction of the lower abdominal wall using the tensor fascia lata muscle flap for post-hemipelvectomy stress urinary incontinence

scientific article published on 22 June 2014

Molecular Taxonomy of Interstitial Cystitis/Bladder Pain Syndrome Based on Whole Transcriptome Profiling by Next-Generation RNA Sequencing of Bladder Mucosal Biopsies

scientific article published on 08 July 2019

Muro-Neuro-Urodynamics; a Review of the Functional Assessment of Mouse Lower Urinary Tract Function.

scientific article published on 06 February 2017

Müllerian duct remnant involving Wolffian system: a case report and literature review.

scientific article

Natural history and etiology of high pressure voiding in male infants

scientific article published on 22 October 2007

Nocturia in men is a chaotic condition dominated by nocturnal polyuria

scientific article published on 29 January 2015

Nomogram for predicting survival of postcystectomy recurrent urothelial carcinoma of the bladder.

scientific article published on 16 January 2017

Oncologic Outcome of Metastasectomy for Urothelial Carcinoma: Who Is the Best Candidate?

scientific article published on 7 July 2017

On‐ and post‐treatment symptom relief by repeated instillations of heparin and alkalized lidocaine in interstitial cystitis ⬇️

scientific article published on February 22, 2013

Overactive bladder is a negative predictor of achieving continence after robot-assisted radical prostatectomy

scientific article published on 11 July 2017

Overactive bladder: pathophysiology, diagnostics, and therapies.

scientific article published on January 2011

Pathology of interstitial cystitis

scientific article published on October 2003

Pathophysiological changes of the lower urinary tract behind voiding dysfunction in streptozotocin-induced long-term diabetic rats

scientific article published on 06 March 2020

Pathophysiology of the underactive bladder

scientific article published on 13 November 2017

Pharmacological profile of β3-adrenoceptor agonists in clinical development for the treatment of overactive bladder syndrome ⬇️

scientific article published on December 21, 2012

Phase III, randomised, double-blind, placebo-controlled study of the β3-adrenoceptor agonist mirabegron, 50 mg once daily, in Japanese patients with overactive bladder

scientific article

Predictive factors for the effect of the α1-D/A adrenoceptor antagonist naftopidil on subjective and objective criteria in patients with neurogenic lower urinary tract dysfunction.

scientific article published on 9 November 2010

Predictors of Early Continence after Robot-assisted Radical Prostatectomy.

scientific article

Preoperative chronic kidney disease is predictive of oncological outcome of radical cystectomy for bladder cancer.

scientific article

Preventive Effects of Long-Term Caloric Restriction on Aging Related In Vivo Bladder Dysfunction and Molecular Biological Changes in the Bladder and Dorsal Root Ganglia in Rats

scientific article published on 31 May 2016

RQ-00434739, a novel TRPM8 antagonist, inhibits prostaglandin E2-induced hyperactivity of the primary bladder afferent nerves in rats

scientific article published on 20 December 2018

Recurrent retroperitoneal malignant nerve sheath tumor associated with neurofibromatosis type 1 responding to carboplatin and etoposide combined chemotherapy

scientific article

Relation between expression of α1-adrenoceptor mRNAs in bladder mucosa and urodynamic findings in men with lower urinary tract symptoms ⬇️

scientific article published on October 21, 2010

Risk factors for clinical metastasis in men undergoing radical prostatectomy and immediate adjuvant androgen deprivation therapy

scientific article

Risk factors for septic shock in acute obstructive pyelonephritis requiring emergency drainage of the upper urinary tract

scientific article

Robot-assisted radical prostatectomy significantly reduced biochemical recurrence compared to retro pubic radical prostatectomy

scientific article

Role of 5-HT receptor antagonists in mediating intracavernous pressure response induced by fluvoxamine in conscious rats

scientific article

Role of alpha1-adrenergic receptors in detrusor overactivity induced by cold stress in conscious rats

scientific article published in January 2009

Role of supraspinal alpha1-adrenoceptors for voiding in conscious rats with and without bladder outlet obstruction

scientific article published in April 2002

Role of supraspinal serotonin receptors for micturition in normal conscious rats

scientific article

Rupture of urachal diverticulum in radiation cystitis and neurogenic bladder dysfunction after radical hysterectomy

scientific article published on 01 October 2004

Safety and efficacy of mirabegron as 'add-on' therapy in patients with overactive bladder treated with solifenacin: a post-marketing, open-label study in Japan (MILAI study)

scientific article published on 23 April 2015

Selective inhibitory effect of imidafenacin and 5-hydroxymethyl tolterodine on capsaicin sensitive C fibers of the primary bladder mechanosensitive afferent nerves in the rat.

scientific article published on 16 September 2014

Sleep Apnea and Circadian Extracellular Fluid Change as Independent Factors for Nocturnal Polyuria

scientific article

Stimulation of skin menthol receptors stimulates detrusor activity in conscious rats.

scientific article published in March 2010

Suppression of detrusor-sphincter dyssynergia by immunoneutralization of nerve growth factor in lumbosacral spinal cord in spinal cord injured rats

scientific article

Symptoms at diagnosis as independent prognostic factors in retroperitoneal liposarcoma

scientific article published on 8 December 2015

Synergic Suppressive Effect of Silodosin and Imidafenacin on Non-Voiding Bladder Contractions in Male Rats with Subacute Bladder Outlet Obstruction

scientific article published on 27 July 2015

Tadalafil for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a review of clinical data in Asian men and an update on the mechanism of action

scientific article

Testicular cancer with tumor thrombus extending to the inferior vena cava successfully removed using veno-venous bypass: a case report

scientific article published in May 2007

The impact of different scenarios for intermittent bladder catheterization on health state utilities: results from an internet-based time trade-off survey

scientific article published on 06 July 2018

The nature of high-pressure voiding in small boys and its relation with the influence of a transurethral catheter

scientific article published on 01 January 2008

The role of transient receptor potential ankyrin 1 (TRPA1) channel in activation of single unit mechanosensitive bladder afferent activities in the rat ⬇️

scientific article published on June 19, 2013

The same-pedicle concept for continent urinary diversion using a Yang-Monti reconfigured tube

scientific article published in January 2004

Therapeutic targets for overactive bladder other than smooth muscle

scientific article

Toll-like receptor 7 is overexpressed in the bladder of Hunner-type interstitial cystitis, and its activation in the mouse bladder can induce cystitis and bladder pain

scientific article published on 6 May 2017

Translation and reliability and validity testing of a Japanese version of the Intermittent Self-Catheterization Questionnaire among disposable and reusable catheter users

scientific article published on 04 October 2016

Transplantation of preserved human amniotic membrane for bladder augmentation in rats

scientific article published on 01 March 2007

Traumatic subcapsular renal lymphocele: an unusual form of Page kidney

scientific article published in September 2009

URB937, a peripherally restricted inhibitor for fatty acid amide hydrolase, reduces prostaglandin E2 -induced bladder overactivity and hyperactivity of bladder mechano-afferent nerve fibres in rats

scientific article published on 18 July 2015

Ultra-early versus early salvage androgen deprivation therapy for post-prostatectomy biochemical recurrence in pT2-4N0M0 prostate cancer

scientific article

Ultrasound-assisted prompted voiding care for managing urinary incontinence in nursing homes: A randomized clinical trial

scientific article published on 08 January 2019

Ultrasound-assisted prompted voiding for management of urinary incontinence of nursing home residents: Efficacy and feasibility.

scientific article published on 11 July 2016

Validation of an educational program balancing surgeon training and surgical quality control during robot-assisted radical prostatectomy

scientific article published on 26 October 2015

Versatility of reconfigured-colon-segment technique for urinary reconstruction requiring use of tubular structures

scientific article published on 01 February 2002

Video-urodynamic effects of mirabegron, a β3 -adrenoceptor agonist, in patients with low-compliance bladder

scientific article published on 14 July 2015

[A case of renal carcinoid with local recurrence and multiple lymph node metastases 4 years after partial nephrectomy]

scientific article published on 01 September 2012

[Eight-year postsurgery recurrence of malignant fibrous histiocytoma of the left spermatic cord]

scientific article published on 01 January 2012

[Intravesical instillation of resiniferatoxin for the patients with interstitial cystitis]

scientific article published on 01 December 2006

β-adrenoceptor agonist effects in experimental models of bladder dysfunction

scientific article published on 12 April 2011

β3 -Adrenoceptors in the normal and diseased urinary bladder-What are the open questions?

scientific article published on 03 May 2019

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