List of works - Dmitry Kuprash

A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a

scientific article published on 01 February 2000

Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice

scientific article published on 28 April 2008

Abnormal hemopoiesis in long-term bone marrow culture from tumor necrosis factor-deficient mice

scientific article published on 01 February 2001

Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus

scientific article published on 01 October 2009

Analysis of tumor antigen-specific T cells and antibodies in cancer patients treated with radiofrequency ablation

scientific article published on 08 October 2010

Antibody response to a non-conserved C-terminal part of human histone deacetylase 3 in colon cancer patients

scientific article published in December 2005

Autoantibodies to tumor-associated antigens as cancer biomarkers.

scientific article

Cellular source and molecular form of TNF specify its distinct functions in organization of secondary lymphoid organs.

scientific article published on 15 July 2010

Chemokines, cytokines and exosomes help tumors to shape inflammatory microenvironment.

scientific article published on 6 September 2016

Cloning and characteristics of murine genes coding for the human GADD45 analog--a protein induced in response to DNA damage

scientific article published in December 1993

Cloning and characterization of TNKL, a member of tankyrase gene family.

scientific article

Cloning and expression analysis of the murine lymphotoxin beta gene.

scientific article

Clusterin is a potential lymphotoxin beta receptor target that is upregulated and accumulates in germinal centers of mouse spleen during immune response

scientific article

Comparative characteristics of transcription of genes for alpha and beta-lymphotoxin subunits in B- and T-lymphocyte lines, in peripheral lymphocytes, and in normal human tissue

scientific article

Conserved kappa B element located downstream of the tumor necrosis factor alpha gene: distinct NF-kappa B binding pattern and enhancer activity in LPS activated murine macrophages

scientific article

Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF.

scientific article

Cyclosporin A blocks the expression of lymphotoxin alpha, but not lymphotoxin beta, in human peripheral blood mononuclear cells.

scientific article published in September 2002

DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-beta) gene

scientific article published in August 1991

Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting

scientific article

Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects.

scientific article published in January 2005

Distinct biological activity of lipopolysaccharides with different lipid A acylation status from mutant strains of Yersinia pestis and some members of genus Psychrobacter.

scientific article published on December 2014

Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo

article

Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues

scientific article published in September 2002

Dynamic changes in chromatin conformation at the TNF transcription start site in T helper lymphocyte subsets

scientific article published on 9 October 2013

Early B-cell factor 1 (EBF1) is critical for transcriptional control of SLAMF1 gene in human B cells.

scientific article published on 14 July 2016

Evaluation of humoral response to tumor antigens using recombinant expression-based serological mini-arrays (SMARTA).

scientific article published in January 2003

Expression of lymphotoxin beta governs immunity at two distinct levels

scientific article published in August 2006

Functional analysis of the lymphotoxin-beta promoter. Sequence requirements for PMA activation.

scientific article

Glucocorticoid Receptor Binding Inhibits an Intronic Enhancer and is Disrupted by rs4742170 (T) Allele Associated with Specific Wheezing Phenotype in Early Childhood

scientific article published in 2018

Homodimer of p50 (NF kappa B1) does not introduce a substantial directed bend into DNA according to three different experimental assays

scientific article (publication date: 11 February 1995)

Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.

scientific article published on 20 November 2007

Humoral immune response to thymidylate synthase in colon cancer patients after 5-FU chemotherapy

scientific article published in August 2005

Immunodetection of Murine Lymphotoxins in Eukaryotic Cells

scientific article published on 01 October 2000

In vitro selection of optimal RelB/p52 DNA-binding motifs

scientific article published on 09 November 2007

Inhibitory effects of tumor necrosis factor on hematopoiesis seen in vitro are translated to increased numbers of both committed and multipotent progenitors in TNF-deficient mice

scientific article published in November 2005

Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.

scientific article published on January 2006

Low level of Lck kinase in Th2 cells limits expression of CD4 co-receptor and S73 phosphorylation of transcription factor c-Jun

scientific article published on 24 May 2017

Lymphotoxin and TNF produced by B cells are dispensable for maintenance of the follicle-associated epithelium but are required for development of lymphoid follicles in the Peyer's patches

scientific article published in July 2004

Mechanisms of Changes in Immune Response during Bacterial Coinfections of the Respiratory Tract.

scientific article published on November 2016

Modalities of experimental TNF blockade in vivo: mouse models.

scientific article published in January 2011

Modeling of viral-bacterial coinfections at the molecular level using agonists of innate immunity receptors.

scientific article published on November 2016

Molecular and Cellular Mechanisms of Inflammation

scientific article

Multiple single nucleotide polymorphisms in the first intron of the IL2RA gene affect transcription factor binding and enhancer activity.

scientific article published on 19 November 2016

New mutations in the human p53 gene--a regulator of the cell cycle and carcinogenesis

scientific article published in March 2007

Nonredundant function of soluble LTα3 produced by innate lymphoid cells in intestinal homeostasis

scientific article

Novel lymphotoxin alpha (LTalpha) knockout mice with unperturbed tumor necrosis factor expression: reassessing LTalpha biological functions.

scientific article

Novel tumor necrosis factor-knockout mice that lack Peyer's patches

scientific article published on 01 May 2005

Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: mouse models

scientific article published on 27 May 2008

Promiscuous survivin peptide induces robust CD4+ T-cell responses in the majority of vaccinated cancer patients

scientific article published on 14 September 2011

RAP80/UIMC1 as cancer-associated antigen: alternative splice variants and their immunogenicity.

scientific article

Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice

scientific article

SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling

scientific article published in February 2004

Serological identification of antigens associated with renal cell carcinoma.

scientific article published in October 2002

Serum Immunoproteomics Combined With Pathological Reassessment of Surgical Specimens Identifies TCP-1ζ Autoantibody as a Potential Biomarker in Thyroid Neoplasia.

scientific article published on 21 July 2015

Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei, Acinetobacter baumannii, and Pseudomonas aeruginosa.

scientific article

TLR-signaling and proinflammatory cytokines as drivers of tumorigenesis

scientific article

TNF in host resistance to tuberculosis infection

scientific article published on 18 February 2010

The role of p105 protein in NFkappaB activation in ANA-1 murine macrophages following stimulation with titanium particles.

scientific article published on July 2002

The single nucleotide variant rs12722489 determines differential estrogen receptor binding and enhancer properties of an IL2RA intronic region

scientific article

Transcriptional Regulation of the Gene, Encoding p40 Subunit of IL-12 and IL-23, in Murine Macrophages

scientific article published on 01 December 2001

Tumor necrosis factor, lymphotoxin and cancer

scientific article published on April 2010

UV fluorescence of tryptophan residues effectively measures protein binding to nucleic acid fragments immobilized in gel elements of microarrays.

scientific article

Upstream open reading frames regulate translation of the long isoform of SLAMF1 mRNA that encodes costimulatory receptor CD150.

scientific article published on December 2014

Use of synthetic oligonucleotides for studying gene structure and polymorphism: human genes encoding tumor necrosis factors and their receptors

scientific article published on 01 January 1991

[A polymorphic markers for the p75 tumor necrosis factor receptor gene: use for analyzing disease linkage]

scientific article published on 01 December 1996

[Characteristics of murine chromosome 17 containing three tumor necrosis factor family genes, including the gene of the transmembrane subunit of lymphotoxin]

scientific article published on 01 August 1994

[Chromosomal localization and molecular organization of human genomic fragment containing TNF/LT locus in transgenic mice]

scientific article published on 01 July 2008

[Cloning and characteristics of the human genome locus containing genes of a second type of receptor (75 kDa) for tumor necrosis factor and lymphotoxin]

scientific article published on 01 January 1991

[Contemporary molecular-biological methods of cancer diagnosis and monitoring based on the humoral immune response to tumor-associated antigens]

scientific article published on 01 January 2007

[Genetic polymorphism of the human genome locus containing the tumor necrosis factor gene: ethnic differences in the allele frequency distribution]

scientific article published on 01 August 1993

[Heterologous expression of murine lymphotoxins in Escherichia coli and preparation of antibodies]

scientific article published on 01 April 1999

[Interaction of transcription factors of the NF-kappa B/rel family with DNA leads to significant bending of it at binding segments]

scientific article published on 01 January 1992

[Interleukin-11, an IL-6 like cytokine]

scientific article published on 01 January 2011

[New putative control elements in the promoter OF CXCL13 chemokine gene, a target of alternative NF-kappaB pathway]

scientific article published on 01 July 2009

[Oncoimmunology: some fundamental problems of cancer immunotherapy]

scientific article published on 01 March 2007

[Onconeural antibodies as a tool for diagnosis of malignant tumors and paraneoplastic neurological disorders]

scientific article published on 01 January 2007

[The molecular cloning and characteristics of the chromosomal copy of the human gene coding for the tumor-necrosis factor receptor]

scientific article published on 01 January 1990

[Transcriptional regulation of TNF/LT locus in immune cells]

scientific article published on 01 January 2011

[Two steps in activating human tumor necrosis factor gene transcription in macrophages. The role of proteins from the NF-kappa B/Rel family in the effect of lipopolysaccharide]

scientific article published on 01 May 1995

p53 is a suppressor of inflammatory response in mice.

scientific article published on 5 April 2005

p53-dependent expression of CXCR5 chemokine receptor in MCF-7 breast cancer cells

scientific article

List of works by Dmitry Kuprash

A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a

Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice

Abnormal hemopoiesis in long-term bone marrow culture from tumor necrosis factor-deficient mice

Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus

Analysis of tumor antigen-specific T cells and antibodies in cancer patients treated with radiofrequency ablation

Antibody response to a non-conserved C-terminal part of human histone deacetylase 3 in colon cancer patients

Autoantibodies to tumor-associated antigens as cancer biomarkers.

Cellular source and molecular form of TNF specify its distinct functions in organization of secondary lymphoid organs.

Chemokines, cytokines and exosomes help tumors to shape inflammatory microenvironment.

Cloning and characteristics of murine genes coding for the human GADD45 analog--a protein induced in response to DNA damage

Cloning and characterization of TNKL, a member of tankyrase gene family.

Cloning and expression analysis of the murine lymphotoxin beta gene.

Clusterin is a potential lymphotoxin beta receptor target that is upregulated and accumulates in germinal centers of mouse spleen during immune response

Comparative characteristics of transcription of genes for alpha and beta-lymphotoxin subunits in B- and T-lymphocyte lines, in peripheral lymphocytes, and in normal human tissue

Conserved kappa B element located downstream of the tumor necrosis factor alpha gene: distinct NF-kappa B binding pattern and enhancer activity in LPS activated murine macrophages

Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF.

Cyclosporin A blocks the expression of lymphotoxin alpha, but not lymphotoxin beta, in human peripheral blood mononuclear cells.

DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-beta) gene

Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting

Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects.

Distinct biological activity of lipopolysaccharides with different lipid A acylation status from mutant strains of Yersinia pestis and some members of genus Psychrobacter.

Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo

Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues

Dynamic changes in chromatin conformation at the TNF transcription start site in T helper lymphocyte subsets

Early B-cell factor 1 (EBF1) is critical for transcriptional control of SLAMF1 gene in human B cells.

Evaluation of humoral response to tumor antigens using recombinant expression-based serological mini-arrays (SMARTA).

Expression of lymphotoxin beta governs immunity at two distinct levels

Functional analysis of the lymphotoxin-beta promoter. Sequence requirements for PMA activation.

Glucocorticoid Receptor Binding Inhibits an Intronic Enhancer and is Disrupted by rs4742170 (T) Allele Associated with Specific Wheezing Phenotype in Early Childhood

Homodimer of p50 (NF kappa B1) does not introduce a substantial directed bend into DNA according to three different experimental assays

Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.

Humoral immune response to thymidylate synthase in colon cancer patients after 5-FU chemotherapy

Immunodetection of Murine Lymphotoxins in Eukaryotic Cells

In vitro selection of optimal RelB/p52 DNA-binding motifs

Inhibitory effects of tumor necrosis factor on hematopoiesis seen in vitro are translated to increased numbers of both committed and multipotent progenitors in TNF-deficient mice

Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.

Low level of Lck kinase in Th2 cells limits expression of CD4 co-receptor and S73 phosphorylation of transcription factor c-Jun

Lymphotoxin and TNF produced by B cells are dispensable for maintenance of the follicle-associated epithelium but are required for development of lymphoid follicles in the Peyer's patches

Mechanisms of Changes in Immune Response during Bacterial Coinfections of the Respiratory Tract.

Modalities of experimental TNF blockade in vivo: mouse models.

Modeling of viral-bacterial coinfections at the molecular level using agonists of innate immunity receptors.

Molecular and Cellular Mechanisms of Inflammation

Multiple single nucleotide polymorphisms in the first intron of the IL2RA gene affect transcription factor binding and enhancer activity.

New mutations in the human p53 gene--a regulator of the cell cycle and carcinogenesis

Nonredundant function of soluble LTα3 produced by innate lymphoid cells in intestinal homeostasis

Novel lymphotoxin alpha (LTalpha) knockout mice with unperturbed tumor necrosis factor expression: reassessing LTalpha biological functions.

Novel tumor necrosis factor-knockout mice that lack Peyer's patches

Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: mouse models

Promiscuous survivin peptide induces robust CD4+ T-cell responses in the majority of vaccinated cancer patients

RAP80/UIMC1 as cancer-associated antigen: alternative splice variants and their immunogenicity.

Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice

SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling

Serological identification of antigens associated with renal cell carcinoma.

Serum Immunoproteomics Combined With Pathological Reassessment of Surgical Specimens Identifies TCP-1ζ Autoantibody as a Potential Biomarker in Thyroid Neoplasia.

Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei, Acinetobacter baumannii, and Pseudomonas aeruginosa.

TLR-signaling and proinflammatory cytokines as drivers of tumorigenesis

TNF in host resistance to tuberculosis infection

The role of p105 protein in NFkappaB activation in ANA-1 murine macrophages following stimulation with titanium particles.

The single nucleotide variant rs12722489 determines differential estrogen receptor binding and enhancer properties of an IL2RA intronic region

Transcriptional Regulation of the Gene, Encoding p40 Subunit of IL-12 and IL-23, in Murine Macrophages

Tumor necrosis factor, lymphotoxin and cancer

UV fluorescence of tryptophan residues effectively measures protein binding to nucleic acid fragments immobilized in gel elements of microarrays.

Upstream open reading frames regulate translation of the long isoform of SLAMF1 mRNA that encodes costimulatory receptor CD150.

Use of synthetic oligonucleotides for studying gene structure and polymorphism: human genes encoding tumor necrosis factors and their receptors

[A polymorphic markers for the p75 tumor necrosis factor receptor gene: use for analyzing disease linkage]

[Characteristics of murine chromosome 17 containing three tumor necrosis factor family genes, including the gene of the transmembrane subunit of lymphotoxin]

[Chromosomal localization and molecular organization of human genomic fragment containing TNF/LT locus in transgenic mice]

[Cloning and characteristics of the human genome locus containing genes of a second type of receptor (75 kDa) for tumor necrosis factor and lymphotoxin]

[Contemporary molecular-biological methods of cancer diagnosis and monitoring based on the humoral immune response to tumor-associated antigens]

[Genetic polymorphism of the human genome locus containing the tumor necrosis factor gene: ethnic differences in the allele frequency distribution]

[Heterologous expression of murine lymphotoxins in Escherichia coli and preparation of antibodies]

[Interaction of transcription factors of the NF-kappa B/rel family with DNA leads to significant bending of it at binding segments]

[Interleukin-11, an IL-6 like cytokine]

[New putative control elements in the promoter OF CXCL13 chemokine gene, a target of alternative NF-kappaB pathway]

[Oncoimmunology: some fundamental problems of cancer immunotherapy]

[Onconeural antibodies as a tool for diagnosis of malignant tumors and paraneoplastic neurological disorders]

[The molecular cloning and characteristics of the chromosomal copy of the human gene coding for the tumor-necrosis factor receptor]

[Transcriptional regulation of TNF/LT locus in immune cells]

[Two steps in activating human tumor necrosis factor gene transcription in macrophages. The role of proteins from the NF-kappa B/Rel family in the effect of lipopolysaccharide]