Search filters

List of works by Frédérique Penault-Llorca

A Retrospective Study on the Onset of Menopause after Chemotherapy: Analysis of Data Extracted from the Jean Perrin Comprehensive Cancer Center Database Concerning 345 Young Breast Cancer Patients Diagnosed between 1994 and 2012.

scientific article

A bivalent role of TIP60 histone acetyl transferase in human cancer

scientific article

A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers

scientific article published on 13 July 2016

Agreement between chromogenic in situ hybridisation (CISH) and FISH in the determination of HER2 status in breast cancer

scientific article published on May 2003

An international Ki67 reproducibility study

scientific article

An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper®

scientific article

Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer

scientific article

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer.

scientific article published on 15 September 2016

Anti-EGFR monoclonal antibodies enhance sensitivity to DNA-damaging agents in BRCA1-mutated and PTEN-wild-type triple-negative breast cancer cells

scientific article published on 19 November 2016

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Ca

scientific article published on 2 August 2017

Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group ⬇️

scientific article published on September 29, 2011

Assessment of epidermal growth factor receptor (EGFR) expression in primary colorectal carcinomas and their related metastases on tissue sections and tissue microarray

scientific article

Autologous fibroblasts as potential vehicle for regional ovarian cancer gene therapy

scientific article published on January 1998

BCRP and P-gp relay overexpression in triple negative basal-like breast cancer cell line: a prospective role in resistance to Olaparib.

scientific article published on 3 August 2015

Biomarkers of residual disease after neoadjuvant therapy for breast cancer

scientific article published on 9 February 2016

Breaking down the Contradictory Roles of Histone Deacetylase SIRT1 in Human Breast Cancer

scientific article published on 30 October 2018

Breast-conserving surgery with or without radiotherapy vs mastectomy for ductal carcinoma in situ: French Survey experience

scientific article published on 10 March 2009

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

scientific article

Cellular Expression of Cyclooxygenase, Aromatase, Adipokines, Inflammation and Cell Proliferation Markers in Breast Cancer Specimen

scientific article published on 2 October 2015

Characteristics and clinical outcome of T1 breast cancer: a multicenter retrospective cohort study

scientific article published on 7 January 2014

Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring study

scientific article

Co-targeting EGFR and mTOR with gefitinib and everolimus in triple-negative breast cancer cells

scientific article published on 14 April 2020

Combination of mTOR and EGFR targeting in an orthotopic xenograft model of head and neck cancer

scientific article published on 24 November 2015

Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer

scientific article published on 10 August 2016

Combined cetuximab and trastuzumab are superior to gemcitabine in the treatment of human pancreatic carcinoma xenografts

scientific article

Combined evaluation of LC3B puncta and HMGB1 expression predicts residual risk of relapse after adjuvant chemotherapy in breast cancer

scientific article published on October 2015

Comparative effects of soy phytoestrogens and 17β-estradiol on DNA methylation of a panel of 24 genes in prostate cancer cell lines

scientific article published on 18 March 2014

Comparative multi-methodological measurement of ERBB2 status in breast cancer

scientific article published on March 2004

Comparison of different commercial kits for HER2 testing in breast cancer: looking for the accurate cutoff for amplification

scientific article

Current perspectives on HER2 testing: a review of national testing guidelines

scientific article

Current status of HER2 testing

scientific article

DNA repair genes implicated in triple negative familial non-BRCA1/2 breast cancer predisposition

scientific article

Daily Practice Management of pT1a-b pN0 Breast Carcinoma: A Prospective French ODISSEE Cohort Study.

scientific article

Development and cytotoxic response of two proliferative MDA-MB-231 and non-proliferative SUM1315 three-dimensional cell culture models of triple-negative basal-like breast cancer cell lines.

scientific article published on 24 August 2017

Development and validation of a high-performance liquid chromatography method for the quantitation of intracellular PARP inhibitor Olaparib in cancer cells

scientific article published on 30 January 2018

Development of automated brightfield double in situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence in situ hybrid

scientific article

Differential Impact of EGFR-Targeted Therapies on Hypoxia Responses: Implications for Treatment Sensitivity in Triple-Negative Metastatic Breast Cancer ⬇️

scientific article published on September 22, 2011

Drug insight: gastrointestinal and hepatic adverse effects of molecular-targeted agents in cancer therapy

scientific article published on 18 March 2008

EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations

scientific article

ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2).

scientific article

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

scientific article

Emerging technologies for assessing HER2 amplification

scientific article

Epigenetic Modifications with DZNep, NaBu and SAHA in Luminal and Mesenchymal-like Breast Cancer Subtype Cells

scientific article published on January 2016

Epigenetic mechanisms of breast cancer: an update of the current knowledge

scientific article published on January 2014

Epigenetic modifications in prostate cancer

scientific article

Evaluation of the immune infiltrate in breast cancer

scientific article

FOXP3 expression in cancer cells and anthracyclines efficacy in patients with primary breast cancer treated with adjuvant chemotherapy in the phase III UNICANCER-PACS 01 trial

scientific article

Frequent EGFR Positivity and Overexpression in High-Grade Areas of Human MPNSTs

scientific article published on January 2008

Global analysis of H3K27me3 as an epigenetic marker in prostate cancer progression

scientific article

HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity ⬇️

scientific article published on June 28, 2013

HER2 testing in gastric cancer: a practical approach ⬇️

scientific article published on January 6, 2012

HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models

scientific article

High inter-observer agreement in immunohistochemical evaluation of HER-2/neu expression in breast cancer: a multicentre GEFPICS study

scientific article published on 20 September 2006

High-throughput «Omics» technologies: New tools for the study of triple-negative breast cancer

scientific article published on 7 March 2016

Impact of EGFR expression on colorectal cancer patient prognosis and survival

scientific article

In vivo efficacy of melanoma internal radionuclide therapy with a 131I-labelled melanin-targeting heteroarylcarboxamide molecule.

scientific article

Instant-quality fluorescence in-situ hybridization as a new tool for HER2 testing in breast cancer: a comparative study

scientific article published on October 2013

Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification

scientific article published on 22 May 2015

Involvement of adiponectin and leptin in breast cancer: clinical and in vitro studies

scientific article

Is Nottingham prognostic index useful after induction chemotherapy in operable breast cancer? ⬇️

scientific article published on October 6, 2003

Is There a Relationship between Ovarian Epithelial Dysplasia and Infertility? ⬇️

scientific article published on February 9, 2012

Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review

scientific article

Ki67 assessment in breast cancer: an update

scientific article published on 5 January 2017

Leptin and leptin receptor involvement in cancer development: a study on human primary breast carcinoma.

scientific article

Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue

scientific article published on 29 October 2013

Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough?

scientific article published on January 2014

Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria

scientific article published on November 2014

Neoadjuvant docetaxel for operable breast cancer induces a high pathological response and breast-conservation rate

scientific article

Pathological and clinical response of a primary chemotherapy regimen combining vinorelbine, epirubicin, and paclitaxel as neoadjuvant treatment in patients with operable breast cancer

scientific article

Pathological and molecular diagnosis of triple-negative breast cancer: a clinical perspective ⬇️

scientific article published on August 1, 2012

Pathological complete response and survival according to the level of HER-2 amplification after trastuzumab-based neoadjuvant therapy for breast cancer

scientific article

Pathology of ovarian cancers in BRCA1 and BRCA2 carriers

scientific article published on April 2004

Patterns of P-glycoprotein activity in the nervous system during vincristine-induced neuropathy in rats

scientific journal article

Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy

scientific article

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype

scientific article published on July 2005

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article

Prognostic significance of a complete pathological response after induction chemotherapy in operable breast cancer

scientific article published on April 2002

Progression-free survival as surrogate end point for overall survival in clinical trials of HER2-targeted agents in HER2-positive metastatic breast cancer

scientific article published on 8 March 2016

Prospective validation of a lymphocyte infiltration prognostic test in stage III colon cancer patients treated with adjuvant FOLFOX.

scientific article published on 23 June 2017

Prostate cancer: The main risk and protective factors-Epigenetic modifications

scientific article

Protein expression, survival and docetaxel benefit in node-positive breast cancer treated with adjuvant chemotherapy in the FNCLCC-PACS 01 randomized trial

scientific article published in November 2011

Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancer

scientific article

Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration

scientific article

Role of neo-adjuvant hormonal therapy in the treatment of breast cancer: a review of clinical trials

scientific article

Routine molecular profiling of patients with advanced non-small-cell lung cancer: results of a 1-year nationwide programme of the French Cooperative Thoracic Intergroup (IFCT).

scientific article published on 14 January 2016

SISH/CISH or qPCR as alternative techniques to FISH for determination of HER2 amplification status on breast tumors core needle biopsies: a multicenter experience based on 840 cases

scientific article

Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group

scientific article published on 24 July 2015

Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group

scientific article published on July 2016

TIP60 Inhibitor TH1834 Reduces Breast Cancer Progression in Xenografts in Mice

scientific article published on 01 September 2019

TIP60: an actor in acetylation of H3K4 and tumor development in breast cancer

scientific article published on 16 October 2018

Testing algorithm for identification of patients with TRK fusion cancer

scientific article published on 09 May 2019

The 21-gene Recurrence Score® assay predicts distant recurrence in lymph node-positive, hormone receptor-positive, breast cancer patients treated with adjuvant sequential epirubicin- and docetaxel-based or epirubicin-based chemotherapy (PACS-01 tria

scientific article published on 4 May 2018

The Epigenetic Landscape of Promoter Genome-wide Analysis in Breast Cancer

scientific article published on 26 July 2017

The European Society of Breast Cancer Specialists recommendations for the management of young women with breast cancer ⬇️

scientific article published on October 29, 2012

The New Synthetic Serum-Free Medium OptiPASS Promotes High Proliferation and Drug Efficacy Prediction on Spheroids from MDA-MB-231 and SUM1315 Triple-Negative Breast Cancer Cell Lines

scientific article published on 21 March 2019

The association between histone 3 lysine 27 trimethylation (H3K27me3) and prostate cancer: relationship with clinicopathological parameters

scientific article

The human FGF9 gene maps to chromosomal region 13q11-q12

scientific article

The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer

scientific article published on 16 March 2016

Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?

scientific article published on January 2006

Triple negative breast cancer: proposals for a pragmatic definition and implications for patient management and trial design

scientific article published on 08 October 2011

Tu-be or not tu-be: That is the question… About serous ovarian carcinogenesis ⬇️

scientific article published on March 22, 2013

Tumour-infiltrating lymphocytes in non-invasive breast cancer: A systematic review and meta-analysis

scientific article published on 09 July 2021

Value and limitations of measuring HER-2 extracellular domain in the serum of breast cancer patients

scientific article published on 02 March 2009

Vertical VEGF targeting: A combination of ligand blockade with receptor tyrosine kinase inhibition

scientific article

WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type

scientific article (publication date: 13 September 2001)

[Erratum to: "Breast cancer screening: On our way to the future" [Bull. Cancer 103 (2016) 753-763]]

scientific article published on 28 October 2016

aHIF but not HIF-1α transcript is a poor prognostic marker in human breast cancer ⬇️

scientific article published on September 26, 2003

Paulina is supported by:

About Paulina

Help