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List of works by Marco A. Pierotti

11q deletions in human colorectal carcinomas: Cytogenetics and restriction fragment length polymorphism analysis

article

4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors

scientific article

45th annual meeting of the Italian Cancer Society. Bergamo, 9-12 November 2003.

scientific article

9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor alpha gene alterations.

scientific article

A Merging Duo in Melanoma Formation

scientific article published on 01 December 2005

A Novel Panel of Antibodies that Segregates Immunocytochemically Poorly Differentiated Carcinoma from Undifferentiated Carcinoma of the Thyroid Gland

scientific article published on October 1, 1994

A bridge over troubled questions

scientific article published on 01 July 2008

A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma

scientific article published on 01 February 1996

A cytogenetic, phenotypic, and molecular study of an immunoblastic lymphoma with a 14q+ translocation

A major susceptibility locus to murine lung carcinogenesis maps on chromosome 6.

scientific article published in February 1993

A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient

scientific article

A normalization strategy for the analysis of plasma microRNA qPCR data in colorectal cancer

scientific article published on 22 October 2013

A novel NTRK1 mutation associated with congenital insensitivity to pain with anhidrosis

scientific article published on April 1999

A novel activating mutation in the RET tyrosine kinase domain mediates neoplastic transformation

scientific article published on 9 February 2006

A polygenic model of inherited predisposition to cancer.

scientific article published on June 1996

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

scientific article published on 22 May 2005

A synovial sarcoma with t(X;18)(p11;q11) in a patient with Turner's syndrome

scientific article

A t(2;3)(q12–13;p24–25) in follicular thyroid adenomas

scientific article published on 01 November 1992

APC Genotype Is Not a Prognostic Factor in Familial Adenomatous Polyposis Patients With Colorectal Cancer

scientific article published on 01 October 2004

Aberrant FHIT transcripts in Merkel cell carcinoma

scientific article published on 01 June 1996

Abnormal expression of histocompatibility antigens on cancer cells

scientific article published on 01 January 1982

Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities

scientific article published on December 1, 1997

Accreditation for excellence of cancer research institutes: recommendations from the Italian Network of Comprehensive Cancer Centers

scientific article

Activate and resist: L576P-KIT in GIST.

scientific article published in September 2009

Activated c-K-ras and c-N-ras oncogenes in 3-methylcholanthrene-induced BALB/c fibrosarcomas.

scientific article

Activated leukocyte cell adhesion molecule expression and shedding in thyroid tumors

scientific article

Activation of ras oncogenes and expression of tumor-specific transplantation antigens in methylcholanthrene-induced murine fibrosarcomas

scientific article published on 01 February 1991

Age at menarche and menopause and breast cancer risk in the International BRCA1/2 Carrier Cohort Study.

scientific article published in April 2007

Age-related activation of the tyrosine kinase receptor protooncogenes RET and NTRK1 in papillary thyroid carcinoma

scientific article published on May 1996

Alien H-2 antigens (H-2k) appearing on a methylcholanthrene-induced tumor (H-2d): biochemical characterization

scientific article published on 01 March 1980

Alien H-2 antigens on a chemically induced fibrosarcoma: further evidence in crude membrane and soluble extracts of the tumor

scientific article published on June 30, 1979

Alien antigens on tumour cells revisited

scientific article published on February 1, 1984

Alien histocompatibility antigens on tumor cells

Allelotyping in Wilms Tumors Identifies a Putative Third Tumor Suppressor Gene on Chromosome 11

article

Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.

scientific article published in September 2004

An unusual BRCA2 allele carrying two splice site mutations

scientific article published on 07 May 2009

Analysis of SHP-1-mediated down-regulation of the TRK-T3 oncoprotein identifies Trk-fused gene (TFG) as a novel SHP-1-interacting protein.

scientific article

Analysis of SYT-SSX fusion transcripts and bcl-2 expression and phosphorylation status in synovial sarcoma.

scientific article published on June 2000

Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients

scientific article published on 01 June 2001

Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells.

scientific article published on 8 January 2007

Analysis of loss of heterozygosity in murine hepatocellular tumors

article

Analysis of potential receptor tyrosine kinase targets in intimal and mural sarcomas

article

Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas

scientific article

Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas

article

Analysis of the retinoic acid receptor α gene as a candidate for the pulmonary adenoma resistance 1 gene

scientific article published on January 1, 1998

Antigen Fluctuation and Virus Activation in EL 4 Cells Transplanted in Hybrid Mice or Cultured In Vitro 2

scientific article published on July 1, 1977

Are two better than one? A novel double-mutant KIT in GIST that responds to Imatinib

scientific article published on 21 March 2013

Association between cigarette smoking and FHIT gene alterations in lung cancer.

scientific article

Association of chromosome 12p genetic polymorphisms with lung adenocarcinoma risk and prognosis

scientific article published in October 1997

Axillary lymph node dissection versus no dissection in patients with T1N0 breast cancer: a randomized clinical trial (INT09/98).

scientific article

BRAF alterations are associated with complex mutational profiles in malignant melanoma

scientific article published in August 2004

Bcl-2 protein expression in carcinomas originating from the follicular epithelium of the thyroid gland

scientific article published on April 1994

BglII polymorphism of the epidermal growth factor receptor (EGF-R) gene

scientific article published on August 1988

Biochemical Uncovering of mdm2/p53 Complexes in Liposarcomas Parallels Their Immunohistochemical Detection

scientific article published on 01 September 1999

Biochemical analysis of a public H-2 specificity revealed by an anomalous reaction of an alloantiserum with a chemically induced C57BL/10 fibrosarcoma

scientific article published on 01 August 1982

Biochemical characterization of alien H-2 antigens expressed on a methylcholanthrene-induced tumor

scientific article published on March 1, 1979

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc

scientific article

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc

scientific article published on 26 May 2016

Biological effects of the dual phenotypic Janus mutation of ret cosegregating with both multiple endocrine neoplasia type 2 and Hirschsprung's disease

scientific article published on 8 January 2004

Breast cancer metastases are molecularly distinct from their primary tumors

scientific article published on 22 October 2007

CD34 expression is regulated reciprocally with adhesion molecules in vascular endothelial cells in vitro

scientific article published on 01 February 1993

CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation

scientific article published on September 2001

CIGNOweb.it.

scientific article

Cancer and inflammation: a complex relationship.

scientific article published on 17 June 2008

Cancer research performance in the European Union: a study of published output from 2000 to 2008.

scientific article published on November 2011

Challenges in projecting clustering results across gene expression-profiling datasets

scientific article

Characterization of papillomavirus polypeptides from bovine cutaneous fibropapillomas

scientific article published on 01 November 1988

Characterization of ten novel and 13 recurring BRCA1 and BRCA2 germline mutations in Italian breast and/or ovarian carcinoma patients. Mutations in brief no. 178. Online

scientific article published on 01 January 1998

Characterization of the NTRK1 genomic region involved in chromosomal rearrangements generating TRK oncogenes.

scientific article published in November 1993

Chromosomal abnormalities in a primary small cell lung cancer

scientific article published on 01 July 1987

Chromosomal localizations and molecular analysis of TDG gene-related sequences

scientific article

Chromosomal rearrangements in thyroid carcinomas: a recombination or death dilemma

scientific article

Chromosome abnormalities and fragile sites in human melanoma

scientific article published on 01 January 1990

Chromosome band 17q21 in breast cancer: Significant association between beclin 1 loss and HER2/NEU amplification

scientific article published on 01 October 2010

Chromosome mapping of murine susceptibility loci to liver carcinogenesis.

scientific article published in January 1993

Chromosome mapping of nine tropomyosin-related sequences in mice

scientific article published on 01 April 1995

Chronology of genetic lesions in lung neoplasia.

scientific article published on January 1997

Circulating free DNA in a screening program for early colorectal cancer detection.

scientific article

Circulating miR-378 in plasma: a reliable, haemolysis-independent biomarker for colorectal cancer

scientific article published on 14 January 2014

Clonal immunoglobulin gene rearrangements and normal T-cell receptor, bcl-2, and c-myc genes in primary cutaneous B-cell lymphomas

scientific article published on 01 September 1989

Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues.

scientific article

Comparison of the breakpoint regions of ELE1 and RET genes involved in the generation of RET/PTC3 oncogene in sporadic and in radiation-associated papillary thyroid carcinomas.

scientific article

Comprehensive cancer control-research & development: knowing what we do and doing what we know.

scientific article published in September 2009

Correspondence re: T. Zhang et al., Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res., 61: 8664-8667, 2001

scientific article published on 01 January 2004

Cross-reactions between tumor cells and allogeneic normal tissues. Inhibition of a syngeneic lymphoma outgrowth in H-2 and non-H-2 alloimmune BALB/c mice.

scientific article

Cyclin D1 expression analysis in familial breast cancers may discriminate BRCAX from BRCA2-linked cases

scientific article published on 7 March 2008

Cyclooxygenase-2 and platelet-derived growth factor receptors as potential targets in treating aggressive fibromatosis

scientific article

Cyclooxygenase-2 expression in FAP patients carrying germ line MYH mutations.

scientific article

Cytogenetic abnormalities and overexpression of receptors for growth factors in normal bronchial epithelium and tumor samples of lung cancer patients

scientific article published on 01 January 1991

Cytogenetic and molecular genetic characterization of papillary thyroid carcinomas

scientific article published on 01 October 1992

Cytogenetic studies in primary and metastatic neuroendocrine merkel cell carcinoma

scientific article published on 01 January 1988

Cytogenetic study in therapy-related myelodysplastic syndromes (t-MDS) and acute non-lymphocytic leukaemia (t-ANLL)

scientific article

DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress-induced apoptosis

scientific article

DNA probes in the characterization of solid tumors

scientific article published on June 1, 1992

DPD and UGT1A1 deficiency in colorectal cancer patients receiving triplet chemotherapy with fluoropyrimidines, oxaliplatin and irinotecan

scientific article

DUSP6/MKP3 is overexpressed in papillary and poorly differentiated thyroid carcinoma and contributes to neoplastic properties of thyroid cancer cells.

scientific article published on 21 January 2013

Data on the topography of the small intestine in humans

scientific article published on March 1970

Deletions of 17p and p53 mutations in preneoplastic lesions of the lung

scientific article published on 01 November 1992

Detection of TP53 mutation, loss of heterozygosity and DNA content in fine-needle aspirates of breast carcinoma

scientific article published on January 1, 1998

Detection of germline BRCA1 mutations by Multiple-Dye Cleavase Fragment Length Polymorphism (MD-CFLP) method

scientific article

Detection of microsatellite alterations in plasma DNA of non-small cell lung cancer patients: a prospect for early diagnosis

scientific article published on 01 October 1999

Detection of microsatellite alterations in the spectrum of melanocytic nevi in patients with or without individual or family history of melanoma

scientific article published on 01 April 2000

Detection of mutated BRAFV600E variant in circulating DNA of stage III–IV melanoma patients

scientific article published on 01 June 2007

Detection of novel mRNA splice variants of human ING4 tumor suppressor gene.

scientific article

Detection of overexpressed and phosphorylated wild-type kit receptor in surgical specimens of small cell lung cancer

scientific article published in December 2004

Detection of p53 point mutations by double-gradient, denaturing gradient gel electrophoresis

scientific article published on 01 December 1997

Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies

scientific article

Different Expressivity of BRCA1 and BRCA2: Analysis of 179 Italian Pedigrees with Identified Mutation

article

Different genetic features associated with colon and rectal carcinogenesis.

scientific article

Different susceptibility to lung tumorigenesis in mice with an identical Kras2 intron 2.

scientific article

Differential interaction of Enigma protein with the two RET isoforms.

scientific article

Differential requirement of Tyr1062 multidocking site by RET isoforms to promote neural cell scattering and epithelial cell branching

scientific article

Discovery of 342 putative new genes from the analysis of 5'-end-sequenced full-length-enriched cDNA human transcripts.

scientific article

Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.

scientific article published on May 1997

Distinct mdm2/p53 expression patterns in liposarcoma subgroups: implications for different pathogenetic mechanisms

scientific article published on 01 January 1997

Disulfide-linked surface molecules of monoclonal antigen-specific suppressor T cells: evidence for T cell receptor structures

scientific article published on 01 August 1985

Dotlike or Golgi-like KIT and PDGFRA Staining in GIST

Downexpression of aldehyde dehydrogenase 1 in murine lung tumors

scientific article published on 01 July 1996

Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa

scientific article

Elevated levels of the acute-phase serum amyloid are associated with heightened lung cancer risk

scientific article

Endogenous murine leukemia virus-encoded proteins in radiation leukemias of BALB/c mice

scientific article published in February 1982

Esthesioneuroblastoma is not a member of the primitive peripheral neuroectodermal tumour-Ewing's group

scientific article published on October 1999

Estrogen Receptor-Beta Expression in Hereditary Breast Cancer

European School of Oncology advisory report. Sun exposure, UVA lamps and risk of skin cancer

scientific article published on 01 January 1994

Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases

scientific article

Evidence for PDGFRA, PDGFRB and KIT deregulation in an NSCLC patient.

scientific article published in January 2007

Evidence for activation of KIT, PDGFRα, and PDGFRβ receptors in the Ewing sarcoma family of tumors

article

Evidence of oncogene-induced senescence in thyroid carcinogenesis.

scientific article published in December 2011

Evidences for association of the CASP8 -652 6N del promoter polymorphism with age at diagnosis in familial breast cancer cases

scientific article published on 16 March 2008

Expression in lung tumors and genetic mapping of the novel murine protein kinase Cη

scientific article published on 01 March 1994

Expression of HER-2/neu gene and protein in salivary duct carcinomas of parotid gland as revealed by fluorescence in-situ hybridization and immunohistochemistry

scientific article published in March 2004

Expression of TRK-T1 oncogene induces differentiation of PC12 cells

scientific article published on 01 July 1993

Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma

scientific article published on February 2004

FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor

scientific article

Familial breast and ovarian cancer: genetic counseling and clinical management in Italy.

scientific article published on October 1999

Flow cytometric detection of the mitochondrial BCL-2 protein in normal and neoplastic human lymphoid cells

scientific article published on 01 January 1992

Fluorescence in situ hybridization analysis and immunophenotyping of c-Kit/PDGFRA and Bcl-2 expression in gastrointestinal stromal tumors.

scientific article

Frequent Mutation and Nuclear Localization of β-Catenin in Sertoli Cell Tumors of the Testis

article

Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas.

scientific article

Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation

scientific article published on May 7, 1998

Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients

article

Functional analysis and molecular modeling show a preserved wild-type activity of p53(C238Y).

scientific article published in June 2006

Functional characterization of NTRK1 mutations identified in melanoma

scientific article published on 26 June 2014

Functional characterization of the MTC-associated germline RET-K666E mutation: evidence of oncogenic potential enhanced by the G691S polymorphism.

scientific article published on 25 July 2011

Functional mapping of receptor tyrosine kinases in myxoid liposarcoma.

scientific article published on 3 June 2010

Gain of function mutations of RTK conserved residues display differential effects on NTRK1 kinase activity.

scientific article

Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer.

scientific article published on 13 July 2010

Gene expression profile identifies a rare epithelioid variant case of pleomorphic liposarcoma carrying FUS-CHOP transcript.

scientific article

Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis

scientific article published on October 2009

Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2.

scientific article published on October 2004

Gene expression profiling of circulating tumor cells in breast cancer.

scientific article

Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland

scientific article

Generation of TSTA diversity. Looking for testable hypotheses

scientific article published on January 1983

Genetic Mapping of the Mouse CDC25Mm Gene, a Ras-Specific Guanine Nucleotide-Releasing Factor, to Chromosome 9

article

Genetic Markers in Sporadic Tumors

Genetic analysis of lung tumours of non-smoking subjects: p53 gene mutations are constantly associated with loss of heterozygosity in the FHIT locus

scientific article published on July 1, 1998

Genetic changes in lung cancer

article

Genetic mapping and expression analysis of the murine DNA ligase I gene

article

Genetic mapping of a pulmonary adenoma resistance locus (Par1) in mouse

scientific article published on 01 April 1996

Genetic mapping of lung cancer modifier loci specifically affecting tumor initiation and progression

scientific article published on 01 October 1997

Genetic mapping of the Brca1 gene on mouse chromosome 11

scientific article published on 01 March 1996

Genetic mapping of thymine DNA glycosylase (Tdg) gene and of one pseudogene in the mouse

scientific article published on 01 December 1996

Genetics of liver tumor susceptibility in mice.

scientific article published on December 1995

Genetics of murine lung tumors.

scientific article published on January 1995

Genomic Landscape of Ovarian Cancer

Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis

scientific article published on 01 March 2001

Germline mutations of TP53 and BRCA2 genes in breast cancer/sarcoma families.

scientific article published on 16 January 2007

Grb2 binding to the different isoforms of Ret tyrosine kinase.

scientific article published on September 1998

Growth-inhibitory effect of STI571 on cells transformed by the COL1A1/PDGFB rearrangement.

scientific article published on May 2001

H2AX phosphorylation and kinetics of radiation-induced DNA double strand break repair in human primary thyrocytes.

scientific article published in March 2009

HER-2/neu Assessment in Primary Chemotherapy Treated Breast Carcinoma: No Evidence of Gene Profile Changing

article

HPV DNA in intraepithelial neoplasia and carcinoma of the vulva and penis

scientific article published on 01 March 1992

HPV detection and p53 alteration in squamous cell verrucous malignancies of the lower genital tract

scientific article published on 01 December 1993

HRAS1 proto-oncogene polymorphisms in human malignant melanoma: TaqI defined alleles significantly associated with the disease

scientific article published on 01 January 1987

Hepatocarcinogenesis: a polygenic model of inherited predisposition to cancer.

scientific article published on January 1996

High CD133 expression levels in gastrointestinal stromal tumors

scientific article published on April 2011

High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma

scientific article published on 01 December 1989

High-Risk Human Papillomavirus Affects Prognosis in Patients With Surgically Treated Oropharyngeal Squamous Cell Carcinoma

scientific article published on 01 December 2006

Homozygous intragenic loss of the WT1 locus in a sporadic intralobar wilms' tumor

scientific article published on 19 August 1993

Human TRK proto-oncogene maps to chromosome 1q32-q41

scientific article published on 01 September 1990

Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cells

scientific article published on 14 December 2000

Human papillomavirus genomes in male urethral cells

scientific article published on November 1, 1992

ICON3 and chemotherapy for ovarian cancer

IGFBP7: an oncosuppressor gene in thyroid carcinogenesis

scientific article

Identification of Shc docking site on Ret tyrosine kinase

scientific article

Identification of a gene expression driven progression pathway in myxoid liposarcoma

scientific article

Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique

scientific article

Identification of the same HRAS1 mutation in a primary minimally invasive follicular carcinoma of the thyroid gland and its bone metastasis developed 15 years later

scientific article published on 01 March 1995

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening

scientific article published on 25 September 2015

Imatinib mesylate in chordoma

scientific article

Immunocytochemical markers in stage I lung cancer: relevance to prognosis

scientific article published on 01 August 1997

Impact of biospecimens handling on biomarker research in breast cancer

scientific article

Improvement of European translational cancer research. Collaboration between comprehensive cancer centers.

scientific article published in March 2008

In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas.

scientific article published on 9 September 2013

In vitro methylation of the human Ha-ras oncogene (T24) affects its transforming activity on NIH/3T3 cells

In vivo resistance and in vitro cellular reactivity against lymphosarcoma cells in immunized mice

scientific article published on 01 July 1978

Induction of RET Proto-Oncogene Expression in Neuroblastoma Cells Precedes Neuronal Differentiation and Is Not Mediated by Protein Synthesis

scientific article published on 01 March 1995

Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene

scientific article

Inflammation and cancer: The oncogene-driven connection

scientific article

Inhibition of interferon-gamma antiviral and antiproliferative activities by ras oncogene expression

scientific article published on July 1989

Insular Carcinoma

scientific article published on 01 December 1997

Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas

scientific article

Integrative approach for prioritizing cancer genes in sporadic colon cancer.

scientific article published in November 2009

International Agency for Research on Cancer workshop on 'Expression array analyses in breast cancer taxonomy'

scientific article published on January 2006

Invasiveness gene signature predicts a favorable outcome also in estrogen receptor-positive primary breast cancers treated with adjuvant tamoxifen

scientific article published on 4 October 2007

Involvement of chromosomes 17 and 22 in dermatofibrosarcoma protuberans.

scientific article published on May 1995

Involvement of the region 13q14 in a patient with adamantinoma of the long bones

scientific article published on 01 October 1990

Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?

scientific article published on December 2008

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

scientific article (publication date: July 2005)

Isolation and mapping to 17p12-13 of the human homologous of the murine growth arrest specific Gas-3 gene

scientific article

Italian performance in cancer research.

scientific article published in March 2009

KIT activation in soft tissue sarcomas

scientific article published on 01 September 2002

KIT/Val654 Ala receptor detected in one imatinib-resistant GIST patient.

scientific article published in February 2005

KRAS and BRAF mutations predict primary resistance to imatinib in gastrointestinal stromal tumors

scientific article published on 26 January 2012

Key role of Shc signaling in the transforming pathway triggered by Ret/ptc2 oncoprotein

scientific article

Lack of H-2Ld locus products on a BALB/c fibrosarcoma expressing H-2k-like alien antigens

scientific article published on 01 April 1983

Lack of SYT-SSX fusion transcripts in malignant peripheral nerve sheath tumors on RT-PCR analysis of 34 archival cases

scientific article published on May 2002

Limited role of TP53 and TP53-related genes in myxoid liposarcoma

scientific article published on 01 September 1998

Limits of predictive models using microarray data for breast cancer clinical treatment outcome

scientific article

Liquid dynamic medicine and N-of-1 clinical trials: a change of perspective in oncology research.

scientific article published on 13 September 2017

Loss of FHIT function in lung cancer and preinvasive bronchial lesions

scientific article published on 01 November 1998

Loss of heterozygosity in human germinal tumors

scientific article published on 01 January 1989

Loss of polymorphic restriction fragments of class I and class II MHC genes in a malignant melanoma

scientific article published on 01 April 1986

Low grade fibromyxoid sarcoma

scientific article published on 01 October 2000

Lung cancer: intragenic ERBB2 kinase mutations in tumours

scientific article

Ly-5 molecular forms in congenitally immunodeficient mice

scientific article published on 01 January 1984

Ly-5.185 molecule is associated with thymic maturation of lymphocytes but not with their cytotoxic activity

scientific article published on 01 January 1987

MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents

scientific article

MIF/CD74 axis is a target for novel therapies in colon carcinomatosis

scientific article

Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient

scientific article published on 01 February 1984

Managing cancer in the EU: The Organisation of European Cancer Institutes (OECI)☆Executive Committee: Ulrik Ringborg (President), Thomas Tursz (Past President), Marco Pierotti (President Elect), Guy Storme (Executive Secretary). E-mail address: ulr

scientific article published on 11 March 2008

Mapping of a Putative Tumor Suppressor Locus to Proximal 7p in Wilms Tumors

scientific article published on 01 November 1996

Mapping of body weight loci on mouse chromosome X.

scientific article published in November 1995

Mapping of the Hmg1 gene and of seven related sequences in the mouse

article

Mean age of tumor onset in hereditary nonpolyposis colorectal cancer (HNPCC) families correlates with the presence of mutations in DNA mismatch repair genes

scientific article published on 01 July 1997

Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma

scientific article

Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production.

scientific article

Methylation status in patients with early stage colon cancer: A new prognostic marker?

scientific article published on 25 April 2011

MicroRNA signature of malignant mesothelioma with potential diagnostic and prognostic implications

scientific article published on 05 June 2009

Microsatellite instability in colorectal-cancer patients with suspected genetic predisposition

scientific article published on 01 January 2000

Molecular Signature of Response to Pazopanib Salvage Therapy for Urothelial Carcinoma.

scientific article published on 7 August 2015

Molecular abnormalities in liposarcoma: role of MDM2 and CDK4-containing amplicons at 12q13-22

scientific article published on 01 June 1998

Molecular and Cytogenetic Subgroups of Oropharyngeal Squamous Cell Carcinoma

scientific article published on 01 November 2006

Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas

scientific article

Molecular and biochemical analysis of RET/PTC4, a novel oncogenic rearrangement between RET and ELE1 genes, in a post-Chernobyl papillary thyroid cancer.

scientific article published in September 1996

Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A

scientific article

Molecular characterization of synovial sarcoma in children and adolescents: evidence of akt activation

scientific article

Molecular cloning of PTC, a new oncogene found activated in human thyroid papillary carcinomas and their lymph node metastases

scientific article published on 01 January 1988

Molecular genetics of breast cancer

scientific article published on September 1, 1997

Molecular genetics of thyroid cancer

article

Molecular pathology of differentiated thyroid cancer.

scientific article published on October 2009

Molecular predictors of response and outcome in ovarian cancer.

scientific article published on 7 July 2006

Monoclonal antibodies against NIH 3T3 cells transformed by human thyroid carcinoma DNA.

scientific article published on February 1988

Morpho-Immunophenotypic-Genotypic Infidelity in Synovial Sarcoma

scientific article published on 01 August 1998

Morphologic-cytogenetic analysis of dedifferentiated liposarcomas with an extensive misleading leiomyosarcomatous component

scientific article published on 01 September 2000

Morphology, growth, and gene expression in five newly isolated murine hepatocellular tumor cell lines.

scientific article

Moving from Discovery to Validation in Circulating microRNA Research

scientific article published on 26 May 2015

Multiple approach to the exploration of genotype-phenotype correlations in familial adenomatous polyposis.

scientific article published in May 2003

Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice

scientific article published in September 1994

Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours.

scientific article

N-(4-hydroxyphenyl)retinamide: a Potent Inducer of Apoptosis in Human Neuroblastoma Cells

scientific article published on 01 August 1994

Natural Antibodies Directed Against Murine Lymphosarcoma Cells 2

scientific article published on October 1, 1975

Natural Antilymphoma Antibodies in C3Hf Mice Serum: Lack of Identity with Autoimmune and anti Murine Leukemia Virus Antibodies

scientific article published on August 31, 1979

Natural antibodies directed against murine lymphosarcoma cells: variability of level in individual mice

scientific article published on August 15, 1976

Nature and properties of C3Hf natural antitumor cytotoxins directed against murine lymphosarcoma cells

scientific article published on 01 September 1976

Need for global action for cancer control

scientific article published on 01 September 2008

No evidence of WT1 involvement in a Burkitt's lymphoma in a patient with Denys-Drash syndrome

scientific article published in June 1998

Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis.

scientific article published on November 1997

Novel Pathogenic Mechanisms of Congenital Insensitivity to Pain with Anhidrosis Genetic Disorder Unveiled by Functional Analysis of Neurotrophic Tyrosine Receptor Kinase Type 1/Nerve Growth Factor Receptor Mutations

scientific article published in Journal of Biological Chemistry

NqA: an R-based algorithm for the normalization and analysis of microRNA quantitative real-time polymerase chain reaction data

scientific article

OncoPan<sup>®</sup>: An NGS-Based Screening Methodology to Identify Molecular Markers for Therapy and Risk Assessment in Pancreatic Ductal Adenocarcinoma

scientific article published on 23 May 2022

Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved.

scientific article published on September 2014

Oncogenic and ligand-dependent activation of KIT/PDGFRA in surgical samples of imatinib-treated gastrointestinal stromal tumours (GISTs).

scientific article published in January 2009

Oncogenic rearrangements of the NTRK1/NGF receptor.

scientific article

Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas

scientific article published on December 1, 1992

Overexpression of the c-MET/HGF receptor in human thyroid carcinomas derived from the follicular epithelium.

scientific article published in February 1995

PCR Analysis of IgH and BCL2 Gene Rearrangement in the Diagnosis of Follicular Lymphoma in Lymph Node Fine-needle Aspiration

article

PDGFRA Immunostaining Can Help in the Diagnosis of Gastrointestinal Stromal Tumors

scientific article published on 01 May 2008

PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor

scientific article published on December 2009

PDGFRalpha, PDGFRbeta and KIT expression/activation in conventional chondrosarcoma.

scientific article published on April 2006

PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients

article

PIK3CA cancer mutations display gender and tissue specificity patterns

scientific article published in February 2008

PP1 inhibitor induces degradation of RETMEN2A and RETMEN2B oncoproteins through proteosomal targeting

scientific article published on May 1, 2003

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

scientific article

Papillomavirus, p53 alteration and primary carcinoma of the vulva

scientific article published on 01 January 1993

Papillomavirus, p53 alteration, and primary carcinoma of the vulva

scientific article published on 01 December 1995

Pas1 is a common lung cancer susceptibility locus in three mouse strains

article

Patterns and changes in gene expression following neo-adjuvant anti-estrogen treatment in estrogen receptor-positive breast cancer

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Phenotype-genotype correlation: challenge of intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses.

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Phosphatase Protein Homologue to Tensin Expression and Phosphatidylinositol-3 Phosphate Kinase Mutations in Colorectal Cancer

Policy statement on multidisciplinary cancer care

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Polygenic inheritance of predisposition to lung cancer.

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Polymorphisms of Metabolizing Enzymes and Susceptibility to Ethmoid Intestinal-type Adenocarcinoma in Professionally Exposed Patients

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Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

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Prediction of TP53 status for primary cisplatin, fluorouracil, and leucovorin chemotherapy in ethmoid sinus intestinal-type adenocarcinoma.

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Preparation of antigenically active membranes from solid murine lymphomas and fibrosarcomas

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Prognostic relevance of MLH1 and MSH2 mutations in hereditary non-polyposis colorectal cancer patients

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Prognostic value of loss of heterozygosity and KRAS2 mutations in lung adenocarcinoma

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Proteomic detection of a large amount of SCGFα in the stroma of GISTs after imatinib therapy

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Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: identification of new signaling elements.

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Proximity ofTPRandNTRK1Rearranging Loci in Human Thyrocytes

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Quantification of free circulating DNA as a diagnostic marker in lung cancer

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Quantitative analysis of plasma DNA in colorectal cancer patients: a novel prognostic tool

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Quantitative and qualitative characterization of plasma DNA identifies primary and recurrent colorectal cancer

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Questioning the utility of pooling samples in microarray experiments with cell lines.

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RET activation in medullary carcinomas.

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RET and NTRK1 proto-oncogenes in human diseases.

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RET inhibition: implications in cancer therapy.

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RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B.

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RET oncoproteins induce tyrosine phosphorylation changes of proteins involved in RNA metabolism

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RET receptor expression in thyroid follicular epithelial cell-derived tumors.

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RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: correlation with clinicopathological features.

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RET/PTC1-driven neoplastic transformation and proinvasive phenotype of human thyrocytes involve Met induction and beta-catenin nuclear translocation

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RETMEN2A and RETMEN2B oncoproteins are targets of PP1 inhibitor.

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RFLP for TaqI of the human thyroid papillary carcinoma (PTC) oncogene

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Rapid assessment of replication error phenotype in gastric cancer

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Rapid differential diagnosis of myxoid liposarcoma by fluorescence in situ hybridisation on cytological preparations.

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Rb and TP53 pathway alterations in sporadic and NF1-related malignant peripheral nerve sheath tumors

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Re: A novel fusion gene, SYT-SSX4, in synovial sarcoma

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Re: Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

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Rearrangements of NTRK1 gene in papillary thyroid carcinoma.

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Rearrangements of RET and NTRK1 tyrosine kinase receptors in papillary thyroid carcinomas.

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Rearrangements of TRK proto-oncogene in papillary thyroid carcinomas.

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Receptor tyrosine kinase and downstream signalling analysis in diffuse malignant peritoneal mesothelioma.

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Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma.

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Receptor tyrosine kinase profiles and human papillomavirus status in oropharyngeal squamous cell carcinoma

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Refined localization of the human TPR gene to chromosome 1q25 by in situ hybridization.

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Refined localization to contiguous regions on chromosome 10q of the two genes (H4 and RET) that form the oncogenic sequence PTC

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Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours

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Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulated bcl-2.

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Regulation of lipocalin-2 gene by the cancer chemopreventive retinoid 4-HPR.

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Relevance of cytogenetic and fluorescent in situ hybridization analyses in the clinical assessment of soft tissue sarcoma.

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Replacement of Fhit in cancer cells suppresses tumorigenicity

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Reply to what if axillary lymph node dissection became less fashionable?

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Report from the OECI Oncology Days 2014

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Reproducibility of a semiquantitative measurement of circulating DNA in plasma from neoplastic patients.

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Response to sunitinib malate in advanced alveolar soft part sarcoma

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Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

scientific article published on May 1992

Ring 22 chromosomes in dermatofibrosarcoma protuberans are low-level amplifiers of chromosome 17 and 22 sequences

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Role of STAT3 in in vitro transformation triggered by TRK oncogenes

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Role of TFG sequences outside the coiled-coil domain in TRK-T3 oncogenic activation.

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Role of antioxidants and intracellular free radicals in retinamide-induced cell death.

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Role of the TFG N-terminus and coiled-coil domain in the transforming activity of the thyroid TRK-T3 oncogene

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Role of the carbohydrate prosthetic groups in the biosynthesis of membrane antigens and in the H-2-restricted lysis of MBL-2 lymphoma cells

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S100A11 overexpression contributes to the malignant phenotype of papillary thyroid carcinoma.

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SNPs in ultraconserved elements and familial breast cancer risk.

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SYT-SSX Fusion Transcripts and Epithelial Differentiation in Synovial Sarcoma

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SYT-SSX fusion genes and prognosis in synovial sarcoma.

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SacI identifies an additional RFLP at the D11S12 locus

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Screening for mutations in exon 11 of the BRCA1 gene in 70 Italian breast and ovarian cancer patients by protein truncation test

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Screening for mutations of the APC gene in 66 Italian familial adenomatous polyposis patients: evidence for phenotypic differences in cases with and without identified mutation

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Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas

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Separation of the tumor-associated transplantation antigen (TATA) from the alien H-2k antigens expressed on a methylcholanthrene-induced tumor

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Solitary fibrous tumors: loss of chimeric protein expression and genomic instability mark dedifferentiation

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Somatic in frame deletions not involving juxtamembranous cysteine residues strongly activate the RET proto-oncogene

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Somatic mutations of the protein kinase gene family in human lung cancer

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Structural features and selective expression of three Ly-5+ cell-surface molecules

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Structure and expression of oncogenes in surgical specimens of human breast carcinomas

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Subcellular Localization of Activated Leukocyte Cell Adhesion Molecule Is a Molecular Predictor of Survival in Ovarian Carcinoma Patients

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Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response

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Sunitinib-induced morpho-functional changes and drug effectiveness in malignant solitary fibrous tumours

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T670X KIT mutations in gastrointestinal stromal tumors: making sense of missense

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TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells.

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TP53 Mutations and mdm2 Protein Overexpression in Cholangiocarcinomas

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TP53 mutations and pathologic complete response to neoadjuvant cisplatin and fluorouracil chemotherapy in resected oral cavity squamous cell carcinoma.

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TP53, p14ARF, p16INK4a and H-ras gene molecular analysis in intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses

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TRAIN: Training through Research Application Italian Initiative

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TRK-A, HER-2/neu, and KIT Expression/Activation Profiles in Salivary Gland Carcinoma

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TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas

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Taking care of smoker cancer patients: a review and some recommendations

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TaqI RFLP of the human tropomyosin gene (TPM3) involved in the generation of the TRK oncogene

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Targeted therapies: the rare cancer paradigm

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Targeted therapy in GIST: in silico modeling for prediction of resistance

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Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects

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The 3rd International Cancer Control Congress: international collaboration in an era of cancer as a global concern.

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The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domain

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The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma.

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The FHIT gene 3p14.2 is abnormal in lung cancer.

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The GIX antigen of murine leukemia virus: an analysis with monoclonal antibodies

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The Gap between Tobacco Treatment Guidelines, Health Service Organization, and Clinical Practice in Comprehensive Cancer Centres

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The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein.

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The M581V mutation, associated with a mild form of congenital insensitivity to pain with anhidrosis, causes partial inactivation of the NTRK1 receptor.

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The Ret(C620R) mutation affects renal and enteric development in a mouse model of Hirschsprung's disease

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The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway.

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The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.

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The expression of MDM2/CDK4 gene product in the differential diagnosis of well differentiated liposarcoma and large deep-seated lipoma.

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The familial medullary thyroid carcinoma-associated RET E768D mutation in a multiple endocrine neoplasia type 2A case

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The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma

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The human archain gene, ARCN1, has highly conserved homologs in rice and Drosophila

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The human tropomyosin gene involved in the generation of the TRK oncogene maps to chromosome 1q31

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The modifier role of RET-G691S polymorphism in hereditary medullary thyroid carcinoma: functional characterization and expression/penetrance studies

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The molecular basis of thyroid epithelial tumorigenesis.

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The molecular understanding of cancer: from the unspeakable illness to a curable disease

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The multiple endocrine neoplasia type 2B point mutation switches the specificity of the Ret tyrosine kinase towards cellular substrates that are susceptible to interact with Crk and Nck

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The oncogene associated with human papillary thyroid carcinoma (PTC) is assigned to chromosome 10 q11-q12 in the same region as multiple endocrine neoplasia type 2A (MEN2A).

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The psychological impact of breast and ovarian cancer preventive options in BRCA1 and BRCA2 mutation carriers

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The role of chromosomal alterations in human cancer development

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The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins.

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The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control

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The two genes generating RET/PTC3 are localized in chromosomal band 10q11.2.

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The use of microarray technologies in clinical oncology

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To bleed or not to bleed. A prediction based on individual gene profiling combined with dose-volume histogram shapes in prostate cancer patients undergoing three-dimensional conformal radiation therapy.

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Transcriptional characteristics of familial non-BRCA1/BRCA2 breast tumors.

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Transforming activity of the chimeric sequence formed by the fusion of collagen gene COL1A1 and the platelet derived growth factor b-chain gene in dermatofibrosarcoma protuberans.

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Tumor location and detection of k-ras mutations in stool from colorectal cancer patients.

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Two RFLPs generated by Taq I at the human HRAS1 locus

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Tyrosines outside the kinase core and dimerization are required for the mitogenic activity of RET/ptc2.

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V. Cutaneous melanoma: Genetics and molecular biology

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Variant translocation t(6;10)(p21;q22) in pulmonary chondroid hamartoma

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Well-differentiated liposarcoma with leiomyomatous differentiation

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When smoke gets in your genes

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Whole exome sequencing and single nucleotide polymorphism array analyses to identify germline alterations in genes associated with testosterone metabolism in a patient with androgen insensitivity syndrome and early-onset colorectal cancer

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[Changes of antigenicity and growth rate of murine sarcomas induced by a chemical carcinogen (author's transl)]

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[Vascularization of the adrenals in Gallus gallus]

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bcl-2 expression in synovial sarcoma

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bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

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c-KIT and c-KIT ligand (SCF) in synovial sarcoma (SS): an mRNA expression analysis in 23 cases

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c-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors.

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c-erbB2/neu gene and chromosome 17 analysis in breast cancer by FISH on archival cytological fine-needle aspirates.

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miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma.

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miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts

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miR-342 overexpression results in a synthetic lethal phenotype in BRCA1-mutant HCC1937 breast cancer cells

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miR-342 regulates BRCA1 expression through modulation of ID4 in breast cancer

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miRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation.

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p15INK4b, p14ARF, and p16INK4a inactivation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors

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p53 activity and chemotherapy

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p53 codon 72 polymorphisms in human papillomavirus-negative and human papillomavirus-positive squamous cell carcinomas of the oropharynx

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p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma

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trk and ret proto-oncogene expression in human neuroblastoma specimens: high frequency of trk expression in non-advanced stages

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