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List of works by Jason Hackney

A developmentally regulated Myb domain protein regulates expression of a subset of stage-specific genes in Entamoeba histolytica

scientific article published on 22 February 2009

A feasibility study of gene gun mediated immunotherapy for renal cell carcinoma

scientific article published in October 1999

A functional genomics approach to hematopoietic stem cell regulation.

scientific article

A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes

scientific journal article

A molecular profile of a hematopoietic stem cell niche

scientific article

A stem cell molecular signature

scientific article

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma

scientific article published on 01 October 2019

Antibody Isotype Switching in Vertebrates

scientific article published on January 2015

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis

scientific article published on 29 October 2015

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

scientific article published on 06 April 2017

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

scientific article published on 29 February 2016

Cutting Edge: IL-17B Uses IL-17RA and IL-17RB to Induce Type 2 Inflammation from Human Lymphocytes

scientific article published on 15 February 2019

Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease

scientific article published on 17 August 2021

Fenebrutinib versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double-Blind, Phase II Trial (ANDES Study)

scientific article published on 09 April 2020

Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q

scientific article (publication date: 2011)

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

scientific article

IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice

scientific article

IL-33 amplifies an innate immune response in the degenerating retina.

scientific article published on 11 January 2016

Identification of developmentally regulated genes in Entamoeba histolytica: insights into mechanisms of stage conversion in a protozoan parasite

scientific article published on 22 January 2007

Identification of putative transcriptional regulatory networks in Entamoeba histolytica using Bayesian inference

scientific article published on 13 March 2007

Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration

scientific article published on 01 January 2020

Mice deficient in NRROS show abnormal microglial development and neurological disorders.

scientific article published in May 2017

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

scientific article published on 01 August 2019

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.

scientific article published on 12 January 2018

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

scientific journal article

Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage

scientific article published on 19 November 2020

Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease

scientific article published on 24 September 2021

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ReportingTools: an automated result processing and presentation toolkit for high-throughput genomic analyses

scientific article

STAT3 activation accompanies keratinocyte differentiation

scientific article

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling.

scientific article

Small RNAs with 5'-polyphosphate termini associate with a Piwi-related protein and regulate gene expression in the single-celled eukaryote Entamoeba histolytica

scientific article

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

scientific article published on 16 March 2019

Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.

scientific article

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohor

scientific article published on 02 October 2019

The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation

scientific article published on 18 January 2019

The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation

scientific article published on 5 May 2016

The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function

scientific article

The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells

scientific article published on 02 June 2020

The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation.

scientific article published on 18 April 2017

The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models

scientific article published on 14 January 2021

Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.

scientific article

Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation

scientific article published on 27 January 2017

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation

scientific article published on 22 December 2013

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis

scientific article published on 18 February 2019

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