List of works by Celine Eidenschenk

A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha

scientific article

A novel developmental and immunodeficiency syndrome associated with intrauterine growth retardation and a lack of natural killer cells

scientific article

A novel immunodeficiency associated with hypomorphic RAG1 mutations and CMV infection

scientific article

A novel primary immunodeficiency with specific natural-killer cell deficiency maps to the centromeric region of chromosome 8.

scientific article

A reversed sulfonamide series of selective RORc inverse agonists

scientific article

Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery

scientific article

Deciphering the crosstalk among IL-1 and IL-10 family cytokines in intestinal immunity

scientific article published on 13 July 2015

Design and Evaluation of Highly Selective Human Immunoproteasome Inhibitors Reveal a Compensatory Process That Preserves Immune Cell Viability

scientific article published on 29 July 2019

Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells

scientific journal article

Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) i

scientific article published on 23 June 2015

Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists

scientific article published on 28 May 2015

Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties

scientific article published on 3 August 2016

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling

scientific article published in February 2018

ENU-induced phenovariance in mice: inferences from 587 mutations

scientific article

Familial NK cell deficiency associated with impaired IL-2- and IL-15-dependent survival of lymphocytes.

scientific article published in December 2006

Fatal varicella associated with selective natural killer cell deficiency

scientific article published on 01 March 2005

Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells

scientific journal article

Genetic analysis of resistance to viral infection

scientific article published on October 2007

Herpes simplex virus encephalitis in human UNC-93B deficiency

scientific article

Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses

scientific article

IL-22, not simply a Th17 cytokine

scientific article published on March 2013

Impact of β2 integrin deficiency on mouse natural killer cell development and function.

scientific article published on 14 January 2011

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

scientific article

Increased susceptibility to DNA virus infection in mice with a GCN2 mutation

scientific article published on 23 November 2011

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

scholarly article

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

scientific article published on 17 April 2017

Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes

scientific article

Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection

scientific article published on 10 February 2015

Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action.

scientific article published on 4 December 2014

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

scientific journal article

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

scientific article published on 22 February 2012

Post-translational regulation of RORγt-A therapeutic target for the modulation of interleukin-17-mediated responses in autoimmune diseases

scientific article

Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists

scientific article

Role of IL-22 in microbial host defense

scientific article published on January 2014

Ru(II)-diimine complexes and cytochrome P450 working hand-in-hand

scientific article published on 12 September 2020

Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc

scientific article

The IL-20 Subfamily of Cytokines and Their Receptors

The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease

scientific article published in December 2009

Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.

scientific article

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes.

scientific article published in April 2018

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis

scientific article published on 18 February 2019

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