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List of works by Miguel A. Peinado

A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA.

scientific article

A knowledgebase of the human Alu repetitive elements.

scientific article published on 28 January 2016

APC promoter is frequently methylated in pancreatic juice of patients with pancreatic carcinomas or periampullary tumors

scientific article published on 15 July 2016

Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells

scientific article published on 27 September 2018

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis

scientific article published on 01 February 2019

Analysis of DNA methylation by amplification of intermethylated sites (AIMS).

scientific article published in January 2009

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer

article

Analysis of differential gene expression in human colorectal tumor tissues by RNA arbitrarily primed-PCR: a technical assessment

article

Androgenic control of immunoreactive somatostatin in the Harderian gland of the Syrian hamster

scientific article published on 01 March 1988

Anti-apoptotic proteins induce non-random genetic alterations that result in selecting breast cancer metastatic cells

scientific article published on January 2005

Apoptosis loss and bcl-2 expression: key determinants of lymph node metastases in T1 breast cancer

scientific article published on 01 November 1996

Arbitrarily Primed-PCR and Related DNA Methylation Methodologies

Assessment of cumulated genetic alterations in colorectal cancer

scientific article

Assessment of genomic damage in colorectal cancer by DNA fingerprinting: prognostic applications

scientific article published on 01 October 1997

Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells.

scholarly article

Brief report: melatonin-related hypogonadotropic hypogonadism

scientific article

CLEAR-test: combining inference for differential expression and variability in microarray data analysis.

scientific article

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

scientific article

Chainy: an universal tool for standardized relative quantification in real-time PCR.

scientific article published on May 2017

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

scientific article

Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.

scientific article published in September 2006

Circulating hypersomatostatinaemia in Menetrier's disease.

scientific article published on March 1991

Colorectal cancer risk and theAPC D1822V variant

scientific article published on 01 October 2004

Common genetic evolutionary pathways in familial adenomatous polyposis tumors

scientific article published in September 2003

Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer

scientific article published on July 1994

Comprehensive measurement of chromosomal instability in cancer cells: combination of fluorescence in situ hybridization and cytokinesis-block micronucleus assay.

scientific article

Cytogenetic characterization of two colon cell lines by using conventional G-banding, comparative genomic hybridization, and whole chromosome painting

scientific article published on August 2000

DCC and SMAD4 alterations in human colorectal and pancreatic tumor dissemination

scientific article published on 01 January 2000

DNA methylation dynamics in cellular commitment and differentiation

scientific article

DNA methylation events in transcription factors and gene expression changes in colon cancer

scientific article published on 22 September 2020

DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis

scientific article published in December 2001

DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.

scientific article

DNA methylation profiling of well-differentiated thyroid cancer uncovers markers of recurrence free survival.

scientific article

Deconstruction of DNA Methylation Patterns During Myogenesis Reveals Specific Epigenetic Events in the Establishment of the Skeletal Muscle Lineage

article published in 2015

Defects in replication fidelity of simple repeated sequences reveal a new mutator mechanism for oncogenesis

scientific article

Detection of differentially expressed gelatinase A in metastatic and non-metastatic subpopulations of tumor cells by target RNA arbitrarily primed polymerase chain reaction (TRAP-PCR)

scientific article published on 01 October 1998

Determination of genomic damage in neuroblastic tumors by arbitrarily primed PCR: MYCN amplification as a marker for genomic instability in neuroblastomas

scientific article published in June 2006

Diet and K-ras mutations in colorectal cancer

scientific article published on 01 January 2002

Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer

scientific article published in December 2004

Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells

scientific article published on 3 February 2009

Discordance between K-ras mutations in bone marrow micrometastases and the primary tumor in colorectal cancer

scientific article published in June 2001

Downregulation of the Deiminase PADI2 Is an Early Event in Colorectal Carcinogenesis and Indicates Poor Prognosis.

scientific article

Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells

scientific article published in September 2011

Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers.

scientific article

Epigenetic deregulation of the COX pathway in cancer

scientific article published on 03 May 2012

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

scientific article

Epigenetics of host-pathogen interactions: the road ahead and the road behind

scientific article

Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer

scientific article published on 24 July 2015

Episodic nyctohemeral secretion of melatonin in adult humans: lack of relation with LH pulsatile pattern

scientific article published on 01 January 1990

Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale

scientific article

Failure of wild-type p53 gene therapy in human cancer cells expressing a mutant p53 protein.

scientific article published in January 1999

Fingerprinting of DNA and RNA by arbitrarily primed polymerase chain reaction: applications in cancer research

scientific article

Functional CpG methylation system in a social insect

scientific article

Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study.

scientific article published on 8 March 2006

Genetic Evolution in the Metastatic Progression of Human Pancreatic Cancer Studied by CGH

scientific article published on 01 December 2001

Genetic and epigenetic markers in the evaluation of pancreatic masses

Genetic determinants of methotrexate responsiveness and resistance in colon cancer cells

scientific article published on October 2005

Genetic evolution in colon cancer KM12 cells and metastatic derivates

scientific article published on July 2004

Genetic instability and divergence of clonal populations in colon cancer cells in vitro.

scientific article published on 21 March 2006

Genetic pathways and genome-wide determinants of clinical outcome in colorectal cancer.

scientific article published in November 2003

Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases

scientific article published on 15 July 2003

Genome-wide tracking of unmethylated DNA Alu repeats in normal and cancer cells.

scientific article published on 15 December 2007

Genomic and transcriptomic prognostic factors in R0 Dukes B and C colorectal cancer patients

scientific article published on 01 May 2007

Genomic determinants of prognosis in colorectal cancer.

scientific article

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

scientific article

Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.

scientific article published in August 2002

Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy

scientific article published in November 2005

Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer.

scientific article published in October 2002

Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status

scientific article (publication date: 2000)

Hypomethylation of DNA

Identification of immunoreactive somatostatin in the rat Harderian gland: Regulation of its content by growth hormone, beta-adrenergic agonists and calcium channel blockers

scientific article published on 01 May 1988

Immunoreactive somatostatin diurnal rhythms in rat pineal, retina and Harderian gland: Effects of sex, season, continuous darkness and estrous cycle

scientific article published on 01 January 1990

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis

article

Increased Global DNA Hypomethylation in Distant Metastatic and Dedifferentiated Thyroid Cancer

scientific article published on 20 November 2017

Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort

scientific article published on 01 January 2019

Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer.

scientific article published on February 2000

Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction

scientific article

Kallikreins Stepwise Scoring Reveals Three Subtypes of Papillary Thyroid Cancer with Prognostic Implications.

scientific article

Ki-ras gene mutations and absence of p53 gene mutations in spontaneous and urethane-induced early lung lesions in CBA/J mice

scientific article published in April 1998

Lack of host-dependent genetic structure in ectoparasites ofCalonectrisshearwaters

article

Long range epigenetic silencing is a trans-species mechanism that results in cancer specific deregulation by overriding the chromatin domains of normal cells.

scientific article published on 30 August 2013

Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease.

scientific article published on 21 April 2009

Methods for DNA methylation analysis and applications in colon cancer

scientific article published on 25 June 2010

Methylation plotter: a web tool for dynamic visualization of DNA methylation data

scientific article

Mismatch repair gene analysis in Catalonian families with colorectal cancer

scientific article published in June 2002

Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer

scientific article

Muscle cell identity requires Pax7-mediated lineage-specific DNA demethylation

scientific article

Mutations in the p53 suppressor gene do not correlate with C-k-ras oncogene mutations in colorectal-cancer

article

Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates

scientific article

Novel methylation panel for the early detection of colorectal tumors in stool DNA.

scientific article published on July 2010

Organochlorine exposure and colorectal cancer risk.

scientific article

Overall deregulation in gene expression as a novel indicator of tumor aggressiveness in colorectal cancer

scientific article published in July 1999

Overlapping DNA methylation dynamics in mouse intestinal cell differentiation and early stages of malignant progression

scientific article published on May 2015

Phylogeography of the Calonectris shearwaters using molecular and morphometric data

scientific article

Plasma Immunoreactive Somatostatin is Elevated in Diabetic Ketoacidosis and Correlates with Plasma Non-esterified Fatty Acid Concentration

scientific article published on 01 May 1987

Prognostic value of genomic damage in non-small-cell lung cancer.

scientific article

Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis

scientific article published in June 2001

Quantification of unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples

scientific article published on 07 February 2016

Redefining the Significance of Aneuploidy in the Prognostic Assessment of Colorectal Cancer

scientific article published on 01 March 2001

Rhythms in pineal immunoreactive somatostatin in the Syrian hamster, mouse, and gerbil

scientific article

Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells

scientific article

Standardized approach for microsatellite instability detection in colorectal carcinomas

scientific article published in April 2000

Standardized approach for microsatellite instability detection in gastric carcinomas

scientific article published in March 2004

Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis

scientific article

Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis

scientific article published on 18 May 2017

The Pancancer DNA Methylation Trackhub: A Window to The Cancer Genome Atlas Epigenomics Data

scientific article published in January 2018

The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells.

scientific article published on 20 December 2016

The structural nature of chromosomal instability in colon cancer cells

scientific article published on 03 December 2002

Tissue and cancer-specific expression of DIEXF is epigenetically mediated by an Alu repeat

scientific article published on 11 February 2020

Tracking recurrent quantitative genomic alterations in colorectal cancer: allelic losses in chromosome 4 correlate with tumor aggressiveness

scientific article published in February 1999

Truke, a web tool to check for and handle excel misidentified gene symbols

scientific article

Tumor Thymidylate Synthase 1494del6 Genotype As a Prognostic Factor in Colorectal Cancer Patients Receiving Fluorouracil-Based Adjuvant Treatment

scientific article published on 01 April 2006

Tumour selection advantage of non-dominant negative P53 mutations in homozygotic MDM2-SNP309 colorectal cancer cells

scientific article published on 6 July 2006

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

scientific article

Validation of RNA arbitrarily primed PCR probes hybridized to glass cDNA microarrays: application to the analysis of limited samples

scientific article published in January 2005

Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer

scientific article

p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.

scientific article published on April 2001

p53 and K-ras gene mutations correlate with tumor aggressiveness but are not of routine prognostic value in colorectal cancer

article

p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas

article

regioneR: an R/Bioconductor package for the association analysis of genomic regions based on permutation tests

scientific article published on 30 September 2015

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