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List of works by Marc Diederich

2,5-Dimethyl-celecoxib inhibits cell cycle progression and induces apoptosis in human leukemia cells

scientific article published on September 2015

4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer

scientific article published on 5 November 2015

4α-Methylated steroids with cytotoxic activity from the soft coral Litophyton mollis

scientific article published on 20 August 2016

5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia

scientific article

A LIM domain protein from tobacco involved in actin-bundling and histone gene transcription.

scientific article published on 28 August 2012

A Survey of Marine Natural Compounds and Their Derivatives with Anti-cancer Activity Reported in 2012.

scientific article published on 20 April 2015

A beginner's guide to NF-kappaB signaling pathways

scientific article

A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death.

scientific article published on 24 October 2013

A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2010.

scientific article published on 30 June 2011

A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2011.

scientific article published on 25 March 2013

About canonical, non-canonical and immunogenic cell death: Basic mechanisms and translational applications: A meeting report of the International Cell Death Society

scientific article published on 14 September 2018

An introduction to the molecular mechanisms of apoptosis

scientific article published on December 2003

Anemia in cancer

scientific article published on October 2010

Antagonistic role of natural compounds in mTOR-mediated metabolic reprogramming

scientific article published on 14 February 2014

Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways.

scientific article published on 10 November 2017

Anti-inflammatory and anticancer drugs from nature

scientific article published on January 2014

Anti-inflammatory, pro-apoptotic, and anti-proliferative effects of a methanolic neem (Azadirachta indica) leaf extract are mediated via modulation of the nuclear factor-κB pathway.

scientific article published on 14 December 2010

Anti-proliferative potential of curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway

scientific article published on 14 January 2011

Anti-proliferative, Cytotoxic and NF-ĸB Inhibitory Properties of Spiro(Lactone-Cyclohexanone) Compounds in Human Leukemia

scientific article published in September 2017

Anticancer and Immunogenic Properties of Cardiac Glycosides

scientific article published on 8 November 2017

Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions.

scientific article published on 20 August 2013

Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity

scientific article published on 22 April 2013

Anticancer potential of naturally occurring immunoepigenetic modulators: A promising avenue?

scientific article published on 06 March 2019

Antioxidant and anti-proliferative properties of lycopene

scientific article published on 26 May 2011

Antiproliferative and proapoptotic activities of 4-hydroxybenzoic acid-based inhibitors of histone deacetylases

scientific article published on 27 September 2013

Antiproliferative effect of natural tetrasulfides in human breast cancer cells is mediated through the inhibition of the cell division cycle 25 phosphatases

scientific article published on 20 January 2011

Assembling the puzzle of anti-cancer mechanisms triggered by cardiac glycosides

scientific article

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

scientific article published on 13 April 2018

Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic cardiac glycoside UNBS1450 in acute myeloid leukemia.

scientific article

Bioactive Bromotyrosine Derivatives from the Pacific Marine Sponge <i>Suberea clavata</i> (Pulitzer-Finali, 1982)

scientific article published on 06 March 2021

Bioactive diterpene derivatives from the marine sponge Spongionella sp.

scientific article published in August 2009

Biotinylation enhances the anticancer effects of 15d‑PGJ2 against breast cancer cells.

scientific article published on 28 March 2018

Bis(4-hydroxy-2H-chromen-2-one): synthesis and effects on leukemic cell lines proliferation and NF-κB regulation.

scientific article published on 6 April 2014

Breakthrough in tracking tumor erythropoietin receptor expression

scientific article published in December 2012

COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells

scientific article published on 24 June 2011

Cancer-type-specific crosstalk between autophagy, necroptosis and apoptosis as a pharmacological target

scientific article published on 03 January 2015

Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.

scientific article published in March 2018

Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials.

scientific article published on 10 June 2013

Cardiac glycosides: From molecular targets to immunogenic cell death.

scientific article

Celecoxib prevents curcumin-induced apoptosis in a hematopoietic cancer cell model.

scientific article published on 5 May 2014

Cell cycle arrest in early mitosis and induction of caspase-dependent apoptosis in U937 cells by diallyltetrasulfide (Al2S4).

scientific article published in May 2009

Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma.

scientific article published on 7 December 2015

Chemopreventive and therapeutic effects of curcumin

scientific article

Chemopreventive potential of curcumin in prostate cancer

scientific article

Chromatin-modifying agents in anti-cancer therapy

scientific article published on 22 May 2012

Coffee provides a natural multitarget pharmacopeia against the hallmarks of cancer

scientific article

Conference Scene: Omic technologies in human disease: extending the network of epigenetic control

scientific article published in October 2011

Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells.

scientific article published in September 2011

Curcumin as a regulator of epigenetic events

scientific article published on 11 June 2013

Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells

scientific article published on 7 September 2006

Curcumin stability and its effect on glutathione S-transferase P1-1 mRNA expression in K562 cells

scientific article published in December 2004

Curcumin-induced cell death in two leukemia cell lines: K562 and Jurkat

scientific article published in December 2003

Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer.

scientific article published on 13 December 2017

Cytotoxic, Antiproliferative and Pro-Apoptotic Effects of 5-Hydroxyl-6,7,3',4',5'-Pentamethoxyflavone Isolated from Lantana ukambensis

scientific article

DNA damage response: the emerging role of c-Abl as a regulatory switch?

scientific article published on 07 July 2011

DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs

scientific article published on 18 January 2012

Decrypting the labyrinth of inflammatory cell signaling pathways: Editorial to the meeting "Inflammation 2010".

scientific article

Dermacozines, a new phenazine family from deep-sea dermacocci isolated from a Mariana Trench sediment.

scientific article

Development of a matrix-assisted laser desorption/ionization-mass spectrometry screening test to evidence reversible and irreversible inhibitors of CDC25 phosphatases

scientific article

Diallylpolysulfides induce growth arrest and apoptosis.

scientific article

Dietary chalcones with chemopreventive and chemotherapeutic potential

scientific article

Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network

scientific article published on 25 January 2012

Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

scientific article

Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells

scientific article published on 19 March 2016

Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450

scientific article

Editorial: Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis

scientific article published on 01 January 2019

Effect of chemopreventive agents on glutathione S-transferase P1-1 gene expression mechanisms via activating protein 1 and nuclear factor kappaB inhibition

scientific article

Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells

scientific article published in August 2009

Effect of curcumin treatment on protein phosphorylation in K562 cells

scientific article published on January 2007

Effects of Natural Products on Mcl-1 Expression and Function

scientific article published on 16 July 2015

Embellicines A and B: Absolute Configuration and NF-κB Transcriptional Inhibitory Activity

scientific article published on 29 March 2013

Energy restriction mimetic agents to target cancer cells: comparison between 2-deoxyglucose and thiazolidinediones.

scientific article published on 30 July 2014

Epigenetic alterations as a universal feature of cancer hallmarks and a promising target for personalized treatments

scientific article published on 25 August 2015

Epigenetic mechanisms underlying the therapeutic effects of HDAC inhibitors in chronic myeloid leukemia

scientific article published on 07 November 2019

Epigenetic modulators from "The Big Blue": a treasure to fight against cancer

scientific article published on 22 June 2014

Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells

scientific article published on April 2013

Epigenetics Offer New Horizons for Colorectal Cancer Prevention

scientific article

Epigenomics of leukemia: from mechanisms to therapeutic applications

scientific article

Epipolythiodiketopiperazines from the Marine Derived Fungus Dichotomomyces cejpii with NF-κB Inhibitory Potential

scientific article

Erythropoietin, erythropoiesis and beyond

scientific article published on 07 July 2011

Eurycomanone and eurycomanol from Eurycoma longifolia Jack as regulators of signaling pathways involved in proliferation, cell death and inflammation.

scientific article published on 16 September 2014

Expression of glutathione S-transferase P1-1 in differentiating K562: role of GATA-1.

scientific article published in November 2003

Expression of glutathione S-transferase P1-1 in leukemic cells is regulated by inducible AP-1 binding

scientific article published in December 2004

Flavonoid glycosides from Olax mannii: Structure elucidation and effect on the nuclear factor kappa B pathway

scientific article published on 13 October 2015

From nature to bedside: pro-survival and cell death mechanisms as therapeutic targets in cancer treatment.

scientific article published on 26 March 2014

GTP-mediated differentiation of the human K562 cell line: transient overexpression of GATA-1 and stabilization of the gamma-globin mRNA.

scientific article published on September 2000

Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues

scientific article

Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

scientific article

Gene expression profiling related to anti-inflammatory properties of curcumin in K562 leukemia cells

scientific article published in August 2009

Gold from the sea: marine compounds as inhibitors of the hallmarks of cancer

scientific article published on March 2011

Goniolandrene A and B from Goniothalamus macrophyllus

scientific article published on 6 April 2013

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HDAC6-an Emerging Target Against Chronic Myeloid Leukemia?

scientific article published on 29 January 2020

Heteronemin, a spongean sesterterpene, inhibits TNF alpha-induced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death

scientific article published on 01 February 2010

Histone deacetylase 6 in health and disease

scientific article

Histone deacetylase modulators provided by Mother Nature

scientific article

Human telomerase reverse transcriptase depletion potentiates the growth-inhibitory activity of imatinib in chronic myeloid leukemia stem cells

scientific article published on 14 November 2019

Hybrid curcumin compounds: a new strategy for cancer treatment.

scientific article

Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release

scientific article published on 08 September 2018

Identification and re-addressing of a transcriptionally permissive locus in the porcine genome

scientific article published on 29 October 2015

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

scientific article published on 06 May 2019

Identification of differentially expressed proteins in curcumin-treated prostate cancer cell lines

scientific article

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

scientific article published on 30 March 2013

Increased glutathione S-transferase P1-1 expression by mRNA stabilization in hemin-induced differentiation of K562 cells

scientific article

Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition

scientific article published in October 2003

Induction of heat shock response by curcumin in human leukemia cells

scientific article published on 25 February 2009

Inflammation: novel arrows for an ancient target

scientific article published on 23 June 2010

Inhibition of TNFalpha-induced activation of nuclear factor kappaB by kava (Piper methysticum) derivatives

scientific article published on 7 February 2006

Inhibitory effect of St. John׳s Wort oil macerates on TNFα-induced NF-κB activation and their fatty acid composition

scientific article

Integrated cellular pathology--systems biology of human diseases

scientific article published on 16 June 2011

Integrated cellular pathology-systems biology of human diseases

scientific article published on 01 January 2012

Intracellular prooxidant activity of melatonin induces a survival pathway involving NF-kappaB activation.

scientific article

Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics

scientific article published on 06 January 2019

Kinase-independent inhibition of cyclophosphamide-induced pathways protects the ovarian reserve and prolongs fertility

scientific article published on 27 September 2019

Linking anemia to inflammation and cancer: the crucial role of TNFalpha

scientific article published on 6 January 2009

Live longer, drink (poly)phenols!

scientific article published on 25 October 2012

Localization of a regulatory region on the 5'-untranslated region of human hepatoma HepG2 gamma-glutamyltransferase mRNA and response to dexamethasone and antisense oligonucleotide treatment

scientific article published on December 1994

Long and short non-coding RNAs as regulators of hematopoietic differentiation

scientific article published on 15 July 2013

Long live the cell death!

scientific article published on 11 April 2008

Magnetic fields promote a pro-survival non-capacitative Ca2+ entry via phospholipase C signaling

scientific article published on 21 November 2010

Marine natural products as targeted modulators of the transcription factor NF-kappaB.

scientific article published on 07 August 2007

Marine natural products targeting phospholipases A2.

scientific article published on 15 September 2010

Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2.

scientific article

Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid

scientific article

Melatonin: a pleiotropic molecule regulating inflammation

scientific article published on 07 August 2010

Metabolism 2014--alterations of metabolic pathways as therapeutic targets

scientific article published on 16 September 2014

Metabolism and cancer: old and new players

scientific article published on 23 June 2013

Metabolomic Tools to Assess the Chemistry and Bioactivity of Endophytic Aspergillus Strain

scientific article

Methylenedioxy flavonoids: assessment of cytotoxic and anti-cancer potential in human leukemia cells.

scientific article published on 3 July 2014

MicroRNAs in cancer management and their modulation by dietary agents

scientific article published on 09 February 2012

Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells

scientific article published on 03 August 2008

Modulation of poly(ADP-ribosylation) in apoptotic cells

scientific article published in September 2004

Modulatory roles of glycolytic enzymes in cell death

scientific article published on 15 July 2014

Molecular and therapeutic potential and toxicity of valproic acid

scientific article

Multistep and multitask Bax activation

scientific article published on 10 August 2010

NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum.

scientific article

NF-κB-Inhibiting Naphthopyrones from the Fijian EchinodermComanthus parvicirrus

article

Natural Compound Histone Deacetylase Inhibitors (HDACi): Synergy with Inflammatory Signaling Pathway Modulators and Clinical Applications in Cancer

scientific article

Natural and Synthetic Flavonoids: Structure-Activity Relationship and Chemotherapeutic Potential for the Treatment of Leukemia

scientific article published on 13 October 2015

Natural chalcones as dual inhibitors of HDACs and NF-κB.

scientific article published on 15 June 2012

Natural compound inducers of immunogenic cell death

scientific article published on 06 April 2019

Natural compounds and pharmaceuticals reprogram leukemia cell differentiation pathways

scientific article published on 14 April 2015

Natural compounds as inflammation inhibitors.

scientific article

Natural compounds as regulators of the cancer cell metabolism

scientific article published on 16 May 2013

Natural dimers of coumarin, chalcones, and resveratrol and the link between structure and pharmacology

scientific article published on 22 August 2019

Natural modulators of the hallmarks of immunogenic cell death

scientific article published on 05 January 2019

Natural products target the hallmarks of chronic diseases

scientific article published on 28 January 2020

Natural scaffolds in anticancer therapy and precision medicine

scientific article published on 03 May 2018

New nodulopeptins from Nodularia spumigena KAC 66

Non-canonical programmed cell death mechanisms triggered by natural compounds.

scientific article published on June 2016

Novel Pharmaceutical Approaches by Natural Compound-Derived Epigenetic Regulators: Epigenetic Readers, Writers and Erasers as Therapeutic Targets

scientific article published on 01 January 2016

Novel antibodies against receptors, protein kinase inhibitors, and siRNA, targeting both signal transduction and gene expression, will certainly lead to the therapeutic approaches that will be developed and used in this new century. Preface

scientific article published on 01 August 2009

Novel inhibitors of human histone deacetylases: design, synthesis and bioactivity of 3-alkenoylcoumarines

scientific article published on 28 June 2014

Novel job opportunities in cell death!

scientific article published on 26 June 2008

OMICS, a multidisciplinary friendship

scientific article published on 2 February 2012

Oxidation-dependent maturation and survival of explanted blood monocytes via Bcl-2 up-regulation

scientific article published on 14 August 2008

Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?

scientific article published on 18 June 2012

Oxidative upregulation of Bcl-2 in healthy lymphocytes.

scientific article

Oxidative, multistep activation of the noncanonical NF-kappaB pathway via disulfide Bcl-3/p50 complex

scientific article

P53 and Sirt1: routes of metabolism and genome stability

scientific article published on 09 September 2014

PPARγ-inactive Δ2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells

scientific article published on 30 November 2013

Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress

scientific article published on 24 January 2013

Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)

scientific article published on 22 February 2019

Perspectives in Medicinal Chemistry: DNA Methylation and Demethylation Mechanisms as Therapeutic Targets?

scientific article published on 01 January 2016

Petromurin C Induces Protective Autophagy and Apoptosis in FLT3-ITD-Positive AML: Synergy with Gilteritinib

scientific article published on 16 January 2020

Phorbol ester regulation of the human gamma-glutamyltransferase gene promoter

scientific article published on January 2004

Phorbol ester responsiveness of the glutathione S-transferase P1 gene promoter involves an inducible c-jun binding in human K562 leukemia cells

scientific article

Plant-derived epigenetic modulators for cancer treatment and prevention

scientific article published on April 2014

Plumbagin modulates leukemia cell redox status.

scientific article

Polyphenol tri-vanillic ester 13c inhibits P-JAK2V617F and Bcr-Abl oncokinase expression in correlation with STAT3/STAT5 inactivation and apoptosis induction in human leukemia cells

scientific article published on 26 June 2013

Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies.

scientific article published on 12 October 2010

Power from the garden: plant compounds as inhibitors of the hallmarks of cancer

scientific article published on January 2012

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

scientific article published on 26 June 2018

Pro-apoptotic and immunostimulatory tetrahydroxanthone dimers from the endophytic fungus Phomopsis longicolla.

scientific article published on 11 December 2013

Pro-inflammatory cytokine-mediated anemia: regarding molecular mechanisms of erythropoiesis

scientific article

Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity

scientific article

Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum

scientific article

Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation

scientific article

ROS-independent JNK activation and multisite phosphorylation of Bcl-2 link diallyl tetrasulfide-induced mitotic arrest to apoptosis.

scientific article

Radicicol-mediated inhibition of Bcr-Abl in K562 cells induced p38-MAPK dependent erythroid differentiation and PU.1 down-regulation

scientific article published in January 2008

Redox biology of regulated cell death in cancer: A focus on necroptosis and ferroptosis

scientific article published on 10 January 2019

Redox regulation: natural compound as regulators of inflammation signaling

scientific article published on 14 July 2012

Regulation of epigenetic traits of the glutathione S-transferase P1 gene: from detoxification toward cancer prevention and diagnosis

scientific article

Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells

scientific article published on April 2004

Regulation of transcription of the glutathione S-transferase P1 gene by methylation of the minimal promoter in human leukemia cells

scientific article

Reply to: Cisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib.

scientific article published in August 2012

Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines

scientific article published on 29 March 2011

Role of Histone Acetylation in Cell Cycle Regulation

scientific article published on 25 August 2015

Roles of Apoptosis and Cellular Senescence in Cancer and Aging

scientific article published on 2 February 2015

Selective antimicrobial activity associated with sulfur nanoparticles.

scientific article published in June 2011

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.

scientific article published on 20 June 2013

Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells

scientific article published on 15 January 2014

Sequential phases of Ca2+ alterations in pre-apoptotic cells.

scientific article published in December 2007

Signal Transducers and Activators of Transcription (STAT) Regulatory Networks in Marine Organisms: From Physiological Observations towards Marine Drug Discovery

scientific article (publication date: August 2015)

Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription.

scientific article

Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells

scientific article published on 13 December 2018

Stress-induced cellular responses in immunogenic cell death: implications for cancer immunotherapy.

scientific article published on 10 February 2018

Styryl-lactone goniothalamin inhibits TNF-α-induced NF-κB activation.

scientific article published on 8 July 2013

Subapoptogenic oxidative stress strongly increases the activity of the glycolytic key enzyme glyceraldehyde 3-phosphate dehydrogenase.

scientific article published in August 2009

Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy

scientific article published on 31 October 2010

Synergistic AML Cell Death Induction by Marine Cytotoxin (+)-1(), 6(), 1'(), 6'(), 11(), 17()-Fistularin-3 and Bcl-2 Inhibitor Venetoclax

scientific article published on 19 December 2018

Synthesis and bioactivity of novel amino-pyrazolopyridines

scientific article published on 5 August 2014

Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin

scientific article published on August 2010

Synthesis and selective anticancer activity of organochalcogen based redox catalysts

scientific article published on October 2010

Synthetic polysulfane derivatives induce cell cycle arrest and apoptotic cell death in human hematopoietic cancer cells.

scientific article published on 21 October 2013

Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities.

scientific article published on 9 June 2015

Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy.

scientific article published on 06 July 2010

Targeting the wingless signaling pathway with natural compounds as chemopreventive or chemotherapeutic agents.

scientific article published on January 2012

Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia

scientific article published on 07 February 2020

The 5' untranslated region of the human γ-glutamyl transferase mRNA contains a tissue-specific active translational enhancer

scientific article published on 01 October 1993

The DNA hypomethylating agent, 5-aza-2'-deoxycytidine, enhances tumor cell invasion through a transcription-dependent modulation of MMP-1 expression in human fibrosarcoma cells.

scientific article published on 4 September 2013

The Eighth Central European Conference "Chemistry towards Biology": Snapshot

scientific article (publication date: 17 October 2016)

The Forty-Sixth Euro Congress on Drug Synthesis and Analysis: Snapshot †.

scientific article published on 28 October 2017

The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition

scientific article

The aromatic ketone 4'-hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition

scientific article published on 14 June 2011

The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer.

scientific article published on 12 December 2017

The dual role of calcium as messenger and stressor in cell damage, death, and survival.

scientific article

The inhibition of TNF-alpha-induced NF-kappaB activation by marine natural products

scientific article

The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies.

scientific article

Traditional West African pharmacopeia, plants and derived compounds for cancer therapy

scientific article published on 28 July 2012

Transcriptional and post-transcriptional regulation of glutathione S-transferase P1 expression during butyric acid-induced differentiation of K562 cells

scientific article

Translational role of natural coumarins and their derivatives as anticancer agents

scientific article published on 29 May 2019

Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.

scientific article

Tumor necrosis factor alpha induces gamma-glutamyltransferase expression via nuclear factor-kappaB in cooperation with Sp1.

scientific article published on 18 October 2008

Tumor necrosis factor alpha inhibits aclacinomycin A-induced erythroid differentiation of K562 cells via GATA-1.

scientific article published on 7 November 2005

Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation

scientific article published on 2 September 2008

Tumor necrosis factor α-mediated inhibition of erythropoiesis involves GATA-1/GATA-2 balance impairment and PU.1 over-expression

scientific article published on 9 April 2011

UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death

scientific article published on 06 February 2009

UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells

scientific article published on 21 September 2010

Valproic acid perturbs hematopoietic homeostasis by inhibition of erythroid differentiation and activation of the myelo-monocytic pathway

scientific article

Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks

scientific article published on 21 September 2014

Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer

scientific article published on 20 August 2013