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List of works by Katalin Mikecz

A Genome Scan Using a Novel Genetic Cross Identifies New Susceptibility Loci and Traits in a Mouse Model of Rheumatoid Arthritis

scientific article published on 01 November 2000

A longitudinal study on an autoimmune murine model of ankylosing spondylitis

scientific article published on 7 January 2005

A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice

scientific article published on 01 September 1995

A triple assay technique for the evaluation of metal-induced, delayed-type hypersensitivity responses in patients with or receiving total joint arthroplasty

article

ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy

scientific article published on 10 June 2013

Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype

scientific article

Adhesion of lymphoid cells to CD44-specific substrata: the consequences of attachment depend on the ligand

scientific article

Age-related changes in arthritis susceptibility and severity in a murine model of rheumatoid arthritis

scientific article published on 11 June 2009

Age-related changes in protein-related epitopes of human articular-cartilage proteoglycans

scientific article published on May 1986

Aggrecan: A Target Molecule of Autoimmune Reactions.

scientific article

Aggrecanolysis in human osteoarthritis: confocal localization and biochemical characterization of ADAMTS5–hyaluronan complexes in articular cartilages

scientific article published on 23 March 2007

Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses

scientific article

Anti-CD44 treatment abrogates tissue aedema and leukocyte infiltration in murine arthrtis

scientific article published on 01 June 1995

Antibody-induced shedding of CD44 from adherent cells is linked to the assembly of the cytoskeleton

scientific article

Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis

article

Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis

scientific article published on 01 September 1995

Antigenic profiles of human, bovine and canine articular chondrocytes

scientific article published on 01 January 1986

Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice

scientific article

BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance

scientific article published on 16 February 2009

CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis ⬇️

scientific article published on January 20, 2003

CD44 expression by leucocytes in rheumatoid arthritis and modulation by specific antibody: implications for lymphocyte adhesion to endothelial cells and synoviocytes in vitro

scientific article published on February 1997

CD44, but not l-selectin, is critically involved in leucocyte migration into the skin in a murine model of allergic dermatitis

scientific article published on 01 September 2005

CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis

scientific article

Cartilage proteoglycan-induced arthritis in BALB/c mice. Antibodies that recognize human and mouse cartilage proteoglycan and can cause depletion of cartilage proteoglycan with little or no synovitis

scientific article published in September 1990

Cartilage proteoglycans as potential autoantigens in humans and in experimental animals

scientific article published on 01 February 1988

Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis

scientific article published in August 2002

Chondrocyte matrix metalloproteinase-8. Human articular chondrocytes express neutrophil collagenase

scientific article

Chondrocyte matrix metalloproteinase-8: up-regulation of neutrophil collagenase by interleukin-1 beta in human cartilage from knee and ankle joints

scientific article published on 01 January 1996

Combined Autoimmune Models of Arthritis Reveal Shared and Independent Qualitative (Binary) and Quantitative Trait Loci

scientific article published on 01 March 2003

Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis

scientific article published on 01 April 2000

Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation

scientific article published on 24 July 2008

Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice

scientific article published on 01 August 2002

Controlled treadmill exercise eliminates chondroid deposits and restores tensile properties in a new murine tendinopathy model

scientific article published on 13 November 2012

Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation

scientific article published on 01 April 1998

Cutting Edge: Regulation of T Cell Activation Threshold by CD28 Costimulation Through Targeting Cbl-b for Ubiquitination

scientific article published on 01 September 2002

Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation

scientific article published on 01 December 2004

Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast-mediated pathologic bone resorption

scientific article published on 01 August 2008

Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.

scientific article

Differential lymphocyte reactivity to serum-derived metal-protein complexes produced from cobalt-based and titanium-based implant alloy degradation

scientific article published on 01 September 2001

Differential recognition of altered peptide ligands distinguishes two functionally discordant (arthritogenic and nonarthritogenic) autoreactive T cell hybridoma clones.

scientific article published on September 2003

Differentially expressed epigenome modifiers, including aurora kinases A and B, in immune cells in rheumatoid arthritis in humans and mouse models.

scientific article

Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis

scientific article

Disease-promoting and -protective genomic loci on mouse chromosomes 3 and 19 control the incidence and severity of autoimmune arthritis.

scientific article

Effects of soluble metals on human peri-implant cells

scientific article published on July 2005

Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice

scientific article published on 01 September 2004

Epigenetics in the pathogenesis of rheumatoid arthritis

scientific article

Expression of CD44 and L-Selectin in the Innate Immune System Is Required for Severe Joint Inflammation in the Proteoglycan-Induced Murine Model of Rheumatoid Arthritis

scientific article published on 01 August 2006

Expression of L-selectin, but not CD44, is required for early neutrophil extravasation in antigen-induced arthritis

scientific article published in June 2004

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

scientific article published on 11 August 2011

Functional assessment of joint use in experimental inflammatory murine arthritis

scientific article published on 01 March 1993

Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation

scientific article

Genetic control of experimental spondylarthropathy

scientific article published on 01 August 2005

Genetics of rheumatoid arthritis - a comprehensive review.

scientific article published on October 2013

Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6.

scientific article

IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis

scientific article

IL-4 and IL-12 Regulate Proteoglycan-Induced Arthritis Through Stat-Dependent Mechanisms

scientific article published on 01 September 2002

IL-4 potentiates activated T cell apoptosis via an IL-2-dependent mechanism

scientific article published in April 2003

Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis

scientific article published on December 1999

Identification of myeloid-derived suppressor cells in the synovial fluid of patients with rheumatoid arthritis: a pilot study

scientific article

Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis

scientific article

Immunity to cartilage proteoglycans in balb/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan

scientific article published on 01 March 1987

Immunomodulation of proteoglycan-induced progressive polyarthritis by lefluflomide

scientific article published on 01 March 1992

Immunoregulation of Proteoglycan-Induced Arthritis in Balb/c Mice

scientific article published on 01 January 1996

Immunosenescence and its potential modulation: lessons from mouse models

scientific article published on 01 May 2010

Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis

scientific article

Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice

scientific article

Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice

scientific article published in May 2003

In vivo two-photon imaging of T cell motility in joint-draining lymph nodes in a mouse model of rheumatoid arthritis

scientific article

Increased resistance to collagen-induced arthritis in CD44-deficient DBA/1 mice

scientific article published in December 2001

Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.

scientific article

Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan

scientific article published on October 2003

Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice

scientific article

Interferon-γ but not granulocyte/macrophage colony-stimulating factor augments proteoglycan presentation by synovial cells and chondrocytes to an autopathogenic T cell hybridoma

scientific article published on 01 February 1995

Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor necrosis factor-stimulated gene-6

scientific article published on 19 November 2012

Isolation of proteoglycan-specific T lymphocytes from patients with ankylosing spondylitis

scientific article

Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models

scientific article published on 26 October 2010

Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis.

scientific article

Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis

scientific article published on 01 January 1995

Mediators and Autopathogenic Effector Cells in Proteoglycan-Induced Arthritic and Clinically Asymptomatic BALB/c Mice

scientific article published on 01 October 1994

Mice lacking endogenous major histocompatibility complex class II develop arthritis resembling psoriatic arthritis at an advanced age

scientific article published on 01 September 2002

Migration and homing of lymphocytes to lymphoid and synovial tissues in proteoglycan–induced murine arthritis

scientific article published on 01 September 1994

Modulation of hyaluronan production by CD44 positive glioma cells

scientific article published on August 2010

Modulation of hyaluronan receptor (CD44) function in vivo in a murine model of rheumatoid arthritis

scientific article published on 01 April 1999

Monoclonal antibodies to different protein-related epitopes of human articular cartilage proteoglycans.

scientific article

Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models

scientific article

Of mice and men: how animal models advance our understanding of T-cell function in RA.

scientific article published on 07 January 2014

Oral glucosamine modulates the response of the liver and lymphocytes of the mesenteric lymph nodes in a papain-induced model of joint damage and repair

scientific article

Orthopaedic implant related metal toxicity in terms of human lymphocyte reactivity to metal-protein complexes produced from cobalt-base and titanium-base implant alloy degradation

article

Osteoarthritis-like damage of cartilage in the temporomandibular joints in mice with autoimmune inflammatory arthritis

scientific article

Particulate-Induced, Prostaglandin- and Cytokine-Mediated Bone Resorption in an Experimental System and in Failed Joint Replacements.

scientific article published on January 1996

Pharmacogenetics and pharmacogenomics in rheumatology.

scientific article

Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan-induced arthritis

scientific article published on April 1995

Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage

scientific article published in June 1998

Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines

scientific article published on 01 November 1999

Proteoglycan aggrecan conducting T cell activation and apoptosis in a murine model of rheumatoid arthritis

scientific article

Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis

scientific article published on 01 January 2004

Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis

scientific article

Proteoglycan-induced arthritis in balb/c mice

scientific article published on 01 February 1987

Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics

scientific article published on January 2003

Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice

scientific article published on 01 June 1990

Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases

scientific article published on October 1990

Role of the extracellular and cytoplasmic domains of CD44 in the rolling interaction of lymphoid cells with hyaluronan under physiologic flow

scientific article published on 22 January 2003

Serum IgE level in systemic lupus erythematosus.

scientific article

Sex effect on clinical and immunologic quantitative trait loci in a murine model of rheumatoid arthritis

scientific article published on 01 June 2003

Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family

scientific article

Spontaneous Thymocyte Apoptosis Is Regulated by a Mitochondrion-Mediated Signaling Pathway

scientific article published on 01 September 2000

Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans

scientific article

Suppression of dendritic cell maturation and T cell proliferation by synovial fluid myeloid cells from mice with autoimmune arthritis.

scientific article

Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow

scientific article

Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14.

scientific article

Systemic metal-protein binding associated with total joint replacement arthroplasty

scientific article published on 01 March 2000

T and B Cell Recovery in Arthritis Adoptively Transferred to SCID Mice: Antigen-Specific Activation Is Required for Restoration of Autopathogenic CD4+ Th1 Cells in a Syngeneic System

scientific article published on 01 June 2002

T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice

scientific article published in February 2012

T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis

scientific article published on 01 June 2005

TSG-6 modulates the interaction between hyaluronan and cell surface CD44.

scientific article published on April 2004

TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthma

scientific article published on November 2012

TSG-6 protein, a negative regulator of inflammatory arthritis, forms a ternary complex with murine mast cell tryptases and heparin

scientific article

TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation

scientific article published on 26 June 2008

Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis

scientific article

Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice

scientific article published on 02 March 2009

The genetic background of ankylosing spondylitis

scientific article published on December 2009

The potential role of fibroblasts in periprosthetic osteolysis: Fibroblast response to titanium particles

scientific article published on 01 September 1995

The role of adhesion molecules in the development of autoimmune arthritis.

scientific article published on January 1995

The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis.

scientific article published on 8 April 2013

Trafficking of CD44-deficient murine lymphocytes under normal and inflammatory conditions

scientific article

Two Loci on Chromosome 15 Control Experimentally Induced Arthritis through the Differential Regulation of IL-6 and Lymphocyte Proliferation

scientific article published on 01 July 2008

Two major interacting chromosome loci control disease susceptibility in murine model of spondyloarthropathy.

scientific article published in August 2005

Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: Evidence of genetically acquired resistance to autoimmune disease

scientific article published on 01 March 2001

Visualization and in situ analysis of leukocyte trafficking into the ankle joint in a systemic murine model of rheumatoid arthritis

scientific article published on 01 October 2005

Vitaxin applied molecular evolution.

scientific article

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