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List of works by Andreas Hofmann

A convenient tool for bivariate data analysis and bar graph plotting with R

scientific article published on 10 January 2019

A deep exploration of the transcriptome and "excretory/secretory" proteome of adult Fascioloides magna.

scientific article

A genome-wide analysis of annexins from parasitic organisms and their vectors

scientific article published on 11 October 2013

A perspective on the discovery of selected compounds with anthelmintic activity against the barber's pole worm-Where to from here?

scientific article published on 04 March 2020

A portrait of the "SCP/TAPS" proteins of eukaryotes--developing a framework for fundamental research and biotechnological outcomes.

scientific article published on 21 February 2009

A practical Java tool for small-molecule compound appraisal

scientific article (publication date: 2015)

A suicide inhibitor of nematode trehalose-6-phosphate phosphatases

scientific article published on 07 November 2019

A theoretical study to establish the relationship between the three-dimensional structure of triose-phosphate isomerase of Giardia duodenalis and point mutations in the respective gene

article

ACDP– a Java application for data processing and analysis of protein circular dichroism spectra

Acid induced equilibrium unfolding of annexin V wild type shows two intermediate states

article

Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms

scientific article

An integrated Java tool for generating amino acid sequence alignments with mapped secondary structure elements

Analysis of the transcriptome of adult Dictyocaulus filaria and comparison with Dictyocaulus viviparus, with a focus on molecules involved in host-parasite interactions

scientific article published on 31 January 2014

Annexin V counteracts apoptosis while inducing Ca(2+) influx in human lymphocytic T cells

scientific article

Arylpyrrole and fipronil analogues that inhibit the motility and/or development of Haemonchus contortus in vitro

article

Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

scientific article published on 31 May 2017

Atypical (RIO) protein kinases from Haemonchus contortus--promise as new targets for nematocidal drugs

scientific article published on 22 January 2011

Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis

scientific article published on 27 April 2016

Biochemical characterization of annexin B1 from Cysticercus cellulosae

scientific article

Bioinformatic exploration of RIO protein kinases of parasitic and free-living nematodes

scientific article published on 17 July 2014

Biophysical characterization of cyclic nucleotide phosphodiesterases

scientific article published in March 2002

CAP protein superfamily members in Toxocara canis

scientific article published on 24 June 2016

Celastrofurans A-G: Dihydro-β-agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells

scientific article

Characterization of a Caenorhabditis elegans glc seven-like phosphatase (gsp) orthologue from Haemonchus contortus (Nematoda).

scientific article published on 12 February 2010

Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284

scientific article

Chromosome-scale Echinococcus granulosus (genotype G1) genome reveals the Eg95 gene family and conservation of the EG95-vaccine molecule

scientific article published on 03 March 2022

Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host

article

Comparison of VILIP-1 and VILIP-3 binding to phospholipid monolayers

scientific article

Coronin 3 involvement in F-actin-dependent processes at the cell cortex

scientific article published on 30 December 2006

Corrigendum

correction published 2007-01-04

Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument

scientific article

Crystal structure of an ASCH protein from Zymomonas mobilis and its ribonuclease activity specific for single-stranded RNA.

scientific article published on 26 September 2017

Crystal structure of the C-terminal tetrad repeat from synexin (annexin VII) of Dictyostelium discoideum

article

Crystal structures of the semireduced and inhibitor-bound forms of cyclic nucleotide phosphodiesterase from Arabidopsis thaliana

scientific article

Crystallization of cyclase-associated protein from Dictyostelium discoideum

scientific article

DMAN: a Java tool for analysis of multi-well differential scanning fluorimetry experiments

scientific article

DRfit: a Java tool for the analysis of discrete data from multi-well plate assays

scientific article published on 21 May 2019

Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets

scientific article published on 4 December 2015

Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain

scientific article published on 7 July 2017

Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase

scientific article published on 31 March 2019

Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c

scientific article published on 12 May 2017

Dihydro-β -agarofurans from the Australian Endemic Rainforest Plant Denhamia pittosporoides Inhibit Leucine Transport in Prostate Cancer Cells

article

Dihydro-β-agarofurans from the roots of the Australian endemic rainforest tree Maytenus bilocularis act as leucine transport inhibitors.

scientific article published on 30 January 2018

Divalent cations and redox conditions regulate the molecular structure and function of visinin-like protein-1

scientific article

Domain Organization of the UBX Domain Containing Protein 9 and Analysis of Its Interactions With the Homohexameric AAA + ATPase p97 (Valosin-Containing Protein)

scientific article published on 23 September 2021

Elucidating the molecular and developmental biology of parasitic nematodes: Moving to a multiomics paradigm

scientific article published on 31 January 2020

Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases

scientific article

Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein

scientific article published on 20 January 2012

Exploring molecular variation in Schistosoma japonicum in China

scientific article published in December 2015

Expression of N471D strumpellin leads to defects in the endolysosomal system

scientific article published on 13 September 2018

Expression, purification and preliminary crystallographic analysis of the recombinant β-glucosidase (BglA) from the halothermophileHalothermothrix orenii

scientific article

Expression, purification, crystallization and preliminary X-ray diffraction analysis of a ribokinase from the thermohalophile Halothermothrix orenii.

scientific article

Flatworms have lost the right open reading frame kinase 3 gene during evolution

scientific article published on 15 May 2015

Genetic analysis of VCP and WASH complex genes in a German cohort of sporadic ALS-FTD patients

scientific article

Genetic blueprint of the zoonotic pathogen Toxocara canis

scientific article published on 4 February 2015

Genome and transcriptome of the porcine whipworm Trichuris suis

scientific article published in July 2014

Global Prevalence Estimates of Toxascaris leonina Infection in Dogs and Cats

scientific article published on 23 June 2020

Global and regional seroprevalence estimates for human toxocariasis: A call for action

scientific article published on 25 April 2020

Global prevalence of Toxocara infection in cats

scientific article published on 25 April 2020

Global prevalence of Toxocara infection in dogs

scientific article published on 26 February 2020

Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions

scientific article

Human toxocariasis

scientific article

Human toxocariasis - A look at a neglected disease through an epidemiological 'prism'

scientific article published on 11 August 2019

Identification of Fromiamycalin and Halaminol A from Australian Marine Sponge Extracts with Anthelmintic Activity against Haemonchus contortus

scientific article published on 23 October 2019

Identification of a Novel Scaffold for Inhibition of Dipeptidyl Peptidase-4

scientific article published on 07 August 2019

Impact of next-generation technologies on exploring socioeconomically important parasites and developing new interventions

scientific article

Insights into SCP/TAPS proteins of liver flukes based on large-scale bioinformatic analyses of sequence datasets

scientific article (publication date: 2012)

Insights into the Membrane Interactions of the Saposin-Like Proteins Na-SLP-1 and Ac-SLP-1 from Human and Dog Hookworm

scientific article

Insights into the immuno-molecular biology of Angiostrongylus vasorum through transcriptomics--prospects for new interventions

scientific article published on 27 July 2013

Interactions of Visinin-like Proteins with Phospho-inositides

article published in 2010

Interactions of benzodiazepine derivatives with annexins

scientific article published in January 1998

Investigating the role of RIO protein kinases in Caenorhabditis elegans.

scientific article

Low cost whole-organism screening of compounds for anthelmintic activity.

scientific article published on 5 March 2015

Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions.

scientific article published on 25 June 2015

Lysosome-associated membrane glycoprotein (LAMP)--preliminary study on a hidden antigen target for vaccination against schistosomiasis ⬇️

scientific article

Major prospects for exploring canine vector borne diseases and novel intervention methods using 'omic technologies ⬇️

scientific article published on April 13, 2011

Mechanism of oligomerisation of cyclase-associated protein from Dictyostelium discoideum in solution

scientific article published on 4 August 2006

Membrane-induced folding and structure of membrane-bound annexin A1 N-terminal peptides: implications for annexin-induced membrane aggregation

scientific journal article

Merging structural biology with chemical biology: Structural Chemistry at Eskitis

article by Andreas Hofmann et al published 28 August 2010 in Structural Chemistry

Molecular alterations during larval development of Haemonchus contortus in vitro are under tight post-transcriptional control

article

Molecular characterization of Schistosoma mansoni tegument annexins and comparative analysis of antibody responses following parasite infection

scientific article published on 16 October 2019

Molecular modeling of prohibitin domains

article

Mutant p97 exhibits species-specific changes of its ATPase activity and compromises the UBXD9-mediated monomerisation of p97 hexamers

scientific article published on 7 April 2016

Natural Compounds from the Marine Brown Alga Caulocystis cephalornithos with Potent In Vitro-Activity against the Parasitic Nematode Haemonchus contortus

scientific article published on 09 July 2020

Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases

scientific article

Non-classical β-carbonic anhydrase inhibitors-towards novel anti-mycobacterials

article

Novel 1-Methyl-1 H-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic Activity

scientific article published on 28 March 2019

Optimization of Novel 1-Methyl-1H-Pyrazole-5-carboxamides Leads to High Potency Larval Development Inhibitors of the Barber's Pole Worm

scientific article published on 29 November 2018

Panel docking of small-molecule libraries - Prospects to improve efficiency of lead compound discovery

scientific article published on 27 May 2015

Parasite annexins--new molecules with potential for drug and vaccine development

scientific article

Pathological consequences of VCP mutations on human striated muscle

scientific article published on 19 September 2006

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration.

scientific article published on 31 January 2012

Phylogenomic and biogeographic reconstruction of the Trichinella complex

scientific article published in February 2016

Plant annexins form calcium-independent oligomers in solution

scientific article published on August 2002

Practical and low cost whole-organism motility assay: A step-by-step protocol.

scientific article

Predicted Coverage and Immuno-Safety of a Recombinant C-Repeat Region Based Streptococcus pyogenes Vaccine Candidate

scientific article

Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings

scientific article published on 18 November 2016

Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling

scientific article published on 19 August 2014

Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2

scientific article

Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors

scientific article

S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases

scientific article

S100A1 and S100B interactions with annexins

article

SBAL: a practical tool to generate and edit structure-based amino acid sequence alignments

scientific article

Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway

scientific article

Screening of a small, well-curated natural product-based library identifies two rotenoids with potent nematocidal activity against Haemonchus contortus.

scientific article published on 11 July 2017

Screening of the 'Open Scaffolds' collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes.

scientific article published on 28 May 2017

Selected α-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro

article

Selenophene and thiophene-core estrogen receptor ligands that inhibit motility and development of parasitic stages of Haemonchus contortus

scientific article

Serine/threonine phosphatases in socioeconomically important parasitic nematodes—Prospects as novel drug targets? ⬇️

scientific article published on August 21, 2010

Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs

scientific article published on 22 July 2011

Specific interaction to PIP2 increases the kinetic rate of membrane binding of VILIPs, a subfamily of Neuronal Calcium Sensors (NCS) proteins

scientific article published on 11 July 2014

Structural Determinants for Plant Annexin−Membrane Interactions†

article

Structural and functional diversity of novel coronin 1C (CRN2) isoforms in muscle.

scientific article

Structural evidence for variable oligomerization of the N-terminal domain of cyclase-associated protein (CAP)

article

Structural optimisation of a conformational epitope improves antigenicity when expressed as a recombinant fusion protein

scientific article published on 01 September 2009

Structure of cyclized green fluorescent protein

scientific article

Structure, function and membrane interactions of plant annexins: an update

scientific article published on 06 June 2011

Structure-Activity Relationship Studies of Tolfenpyrad Reveal Subnanomolar Inhibitors of Haemonchus contortus Development

article

Structure-function analysis of apical membrane-associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control

scientific article

Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseases.

scientific article published on 9 September 2010

Synthesis and structure-activity relationship study of pyrrolidine-oxadiazoles as anthelmintics against Haemonchus contortus

scientific article published on 25 January 2020

Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of Haemonchus contortus In Vitro

scientific article published on 24 April 2020

TIMPs of parasitic helminths - a large-scale analysis of high-throughput sequence datasets

scientific article published on 30 May 2013

Tetrahydroquinoxalines induce a lethal evisceration phenotype in Haemonchus contortus in vitro

scientific article published on 30 December 2018

The Annexin A3−Membrane Interaction Is Modulated by an N-Terminal Tryptophan†

article

The Haemonchus contortus kinome--a resource for fundamental molecular investigations and drug discovery

scientific article

The Opisthorchis viverrini genome provides insights into life in the bile duct

scientific article published on 9 July 2014

The Relevance of Structural Biology in Studying Molecules Involved in Parasite–Host Interactions: Potential for Designing New Interventions

The barber's pole worm CAP protein superfamily--A basis for fundamental discovery and biotechnology advances

scientific article published on 31 July 2015

The complement of family M1 aminopeptidases of Haemonchus contortus--Biotechnological implications.

scientific article

The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster

scientific article (publication date: June 2003)

The crystal structure of calcium-bound annexin Gh1 from Gossypium hirsutum and its implications for membrane binding mechanisms of plant annexins

scientific article

The developmental phosphoproteome of Haemonchus contortus

scientific article published on 14 December 2019

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus

scientific article

The iron distribution and magnetic properties of schistosome eggshells: implications for improved diagnostics

scientific article (publication date: 2013)

Trehalose 6-phosphate phosphatases of Pseudomonas aeruginosa.

scientific article published on 24 April 2018

Trehalose-6-phosphate phosphatase as a broad-spectrum therapeutic target against eukaryotic and prokaryotic pathogens

Two practical Java software tools for small-angle X-ray scattering analysis of biomolecules

scholarly article by Andreas Hofmann & Andrew E Whitten published 28 March 2014 in Journal of Applied Crystallography

Using UHPLC-MS Profiling for the Discovery of New Dihydro-β-Agarofurans from Australian Celastraceae Plant Extracts

article

VCP and PSMF1: Antagonistic regulators of proteasome activity

scientific article published on 15 June 2015

Whole-genome sequence of Schistosoma haematobium

scientific article

Zea mays annexins modulate cytosolic free Ca2+ and generate a Ca2+-permeable conductance

scientific article published on 20 February 2009

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