List of works - Eva Freisinger

(Z)-2-Phenyl-3-pivaloyl-1,1-dipropyl-guanidine.

scientific article

A Family of Hydrazone-Based Nucleosides for Use in Metal-Mediated Base Pairs

Affinity of the Iminooxo Tautomer Anion of 1-Methylcytosine intrans-[Pt(NH3)2(1-MeC-N4)2]2+ for Heterometals

An optimized intein-mediated protein ligation approach for the efficient cyclization of cysteine-rich proteins

scientific article

Analogues of Cis- and Transplatin with a Rich Solution Chemistry: cis-[PtCl2 (NH3 )(1-MeC-N3)] and trans-[PtI2 (NH3 )(1-MeC-N3)].

scientific article published on 23 October 2015

Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction

scientific article

Cadmium in Metallothioneins

scientific article (publication date: 3 November 2012)

Canonical and unconventional pairing schemes between bis(nucleobase) complexes of trans-a2PtII: artificial nucleobase quartets and C-H...N bonds

scholarly article

Celebrating Helmut Sigel.

scientific article published on 7 December 2017

Comparison of the surprising metal-ion-binding properties of 5- and 6-uracilmethylphosphonate (5Umpa2- and 6Umpa2-) in aqueous solution and crystal structures of the dimethyl and di(isopropyl) esters of H2(6Umpa).

scientific article

Connectivity patterns and rotamer states of nucleobases determine acid–base properties of metalated purine quartets

scientific article published on 16 February 2015

Different Behavior of the Histidine Residue toward Cadmium and Zinc in a Cadmium-Specific Metallothionein from an Aquatic Fungus

scientific article published on 18 November 2020

Diplatinum(III) complexes with bridging 1-methylcytosinate ligands and variable axial ligands, including guanine nucleobases

Diplatinum(III) complexes with four bridging 1-methylcytosinato nucleobases derived from a mononuclear trans-(NH3)2PtII complex and CuII.

scientific article

Discrete Molecular Squares {[(en)M(CN)]4}4+ Derived from [(en)M(CN)2] (M = PtII, PdII)

Effects of N7-methylation, N7-platination, and C8-hydroxylation of guanine on H-bond formation with cytosine: platinum coordination strengthens the Watson-Crick pair

scientific article published on 01 June 2000

Exocyclic oxygen atoms of platinated nucleobases as binding sites for alkali metal ions †

From nucleotides to ribozymes—A comparison of their metal ion binding properties

From simple trans-[a2Pt(2-hydroxypyrimidine)2]2+ (a = NH3, CH3NH2) complexes to structures of higher complexity. Molecular recognition of 2-aminopyrimidine by hydrogen bond formation and reactivity toward additional metal ions

scientific article

Further insights into the metal ion binding abilities and the metalation pathway of a plant metallothionein from Musa acuminata

scientific article published on 7 December 2017

Hydrogen bonding patterns of 7,9-dimethylguanine and its transplatinum(II) complexes

Hydrogen bonding patterns of N(7) platinated guanine: Watson–Crick and different self-pairing motifs in a tris(9-methylguanine) complex of PtII †

Impact of naturally occurring serine/cysteine variations on the structure and function of Pseudomonas metallothioneins

scientific article published on 01 January 2020

Incorporation of sulfide ions into the cadmium(II) thiolate cluster of Cicer arietinum metallothionein2.

scientific article published on 28 December 2012

Inter- and intra-molecular condensation patterns of (en)PdII with trans-[a2PtL2]2+ (a = am(m)ine, L = 2-aminopyridine): PtPd3 and Pt2Pd4 species with multiple amide bridges. Unexpected trapping of a pair of nitrate ions by a Pt2Pd4 double coneElectro

article by Bettina Beck et al published 2003 in Dalton Transactions

Interaction of Pt(II) and Pd(II) complexes of terpyridine with 1-methylazoles: A combined experimental and density functional study

Investigating the influence of histidine residues on the metal ion binding ability of the wheat metallothionein γ-Ec-1 domain

scientific article published on 8 August 2015

Lesion (in)tolerance reveals insights into DNA replication fidelity

scientific article

Localization and Spectroscopic Analysis of the Cu(I) Binding Site in Wheat Metallothionein Ec-1

scientific article published on 11 March 2016

Metal ion binding properties of Triticum [corrected] aestivum Ec-1 metallothionein: evidence supporting two separate metal thiolate clusters

scientific article published on 9 January 2007

Metal ion binding properties of Triticum aestivum Ec-1 metallothionein: evidence supporting two separate metal thiolate clusters

article

Metal ion release from metallothioneins: proteolysis as an alternative to oxidation

scientific article published on September 2013

Metal-modified nucleobase pairs and triplets as cytosine receptors

scientific article published in May 2001

Metal-modified nucleobase sextet: joining four linear metal fragments (trans-a2PtII) and six model nucleobases to an exceedingly stable entity.

scientific article published in May 2001

Metal-stabilized rare tautomers of nucleobases. 8. Promotion of rare cytosine tautomer upon complex formation with (dien)M2+ (M=Pt, Pd)

Metalated Nucleobase Quartets: Dimerization of a Metal-Modified Guanine, Cytosine Pair oftrans-(NH3)2PtIIand Formation of CH···N Hydrogen Bonds

scientific article published in 1998

Mixed-metal (platinum, palladium), mixed-pyrimidine (uracil, cytosine) self-assembling metallacalix[n]arenes: dynamic combinatorial chemistry with nucleobases and metal species

scientific article

Molecular Architecture Based on Metal Triangles Derived from 2,2‘-Bipyrazine (Bpz) and EnMII(M = Pt, Pd)

article by Ralf-Dieter Schnebeck et al published February 2000 in Journal of the American Chemical Society

N-Methyl-2, 2'-Dipicolylamine Complexes as Potential Models for Metal-Mediated Base Pairs

N1 and N3 linkage isomers of neutral and deprotonated cytosine with trans-[(CH3NH2)2PtII.

scientific article

NMR spectroscopy in bioinorganic chemistry

scientific article published on January 2012

On the interrelationship of mu-OH bridged dimers, trimers, and tetramers of (en)PtII and their Ag+ adducts

scientific article

Oxidation of the N-terminal domain of the wheat metallothionein Ec -1 leads to the formation of three distinct disulfide bridges

scientific article published on 7 April 2016

Pd(II) and Pt(II) (R,S)-3-aminopyrrolidine complexes. Reactions with 9-ethylguanine and study of their antiproliferative activity

Pd(II)- and Pt(II)-cimetidine complexes. Crystal structure of trans-[Pt(N,S-cimetidine)2]Cl2.12H2O

scientific article published on 01 April 2002

Plant MTs-long neglected members of the metallothionein superfamily

scientific article published on 29 October 2008

Preface

scientific article published on 01 August 2014

Preface for the JIB Special Issue for the 12th European Biological Inorganic Chemistry Conference (EuroBIC 12) in Zurich, Switzerland, August 24–28, 2014

article

Protein and metal cluster structure of the wheat metallothionein domain γ-E(c)-1: the second part of the puzzle

scientific article

PtII Binding to N1 of Cytosine: Strengthening the Watson-Crick Pair with Guanine and yet Confining Its pH Existence Range

Pyrazine as a building block for molecular architectures with PtII.

scientific article

Reactivity of an extremenly sterically crowded monofunctional Pt complex, [Pt(1-MeC-N3)3(H2O)]2+ (1-MeC=1-methylcytosine), toward model nucleobases and selectivity toward guanine in single- and double-stranded deoxyoligonucleotides

scientific article published on 01 February 1999

Self-assembly of palladium(II) and platinum(II) complexes of 2-hydroxypyrimidine to novel metallacalix[4]arenes. Receptor properties through multiple H-bonding interactions.

scientific article

Sequence-Specific Post-Synthetic Oligonucleotide Labeling for Single-Molecule Fluorescence Applications

scientific article published on 13 July 2016

Sequence-specific generation of 1,N(6)-ethenoadenine and 3,N(4)-ethenocytosine in single-stranded unmodified DNA.

scientific article published on 24 November 2014

Site-Specific Dual-Color Labeling of Long RNAs

scientific article published on 01 January 2020

Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy.

scientific article published on 9 November 2017

Solution structure of the circular γ-domain analog from the wheat metallothionein E(c)-1

scientific article

Stick, Flick, Click: DNA-guided Fluorescent Labeling of Long RNA for Single-molecule FRET

scientific article published on 01 April 2019

Structural features specific to plant metallothioneins ⬇️

scientific article published on June 19, 2011

Sulfide ions as modulators of metal-thiolate cluster size in a plant metallothionein

scientific article published on 2 May 2013

Supramolecular isomerism of 2,2'-bipyrazine complexes with cis-(NH(3))(2)Pt(II): ligand rotational state and sequential orientation determine the 3D shape of metallacycles

scientific article

Synthetic Ways to Tris(nucleobase) Complexes Derived from cis-Diammineplatinum(II) and a Platinum(II) Complex Containing Four Different Ligands, Three of Which Are Nucleobases

scientific article

The Bioinorganic Periodic Table

scientific article published on 01 March 2019

The Metal-Thiolate Clusters of Plant Metallothioneins ⬇️

scientific article published on January 1, 2010

The beta(E)-domain of wheat E(c)-1 metallothionein: a metal-binding domain with a distinctive structure

scientific article

The major function of a metallothionein from the aquatic fungus Heliscus lugdunensis is cadmium detoxification

scientific article

The plant metallothionein 2 from Cicer arietinum forms a single metal-thiolate cluster

scientific article published on 18 August 2009

The two distinctive metal ion binding domains of the wheat metallothionein Ec-1

scientific article published on 28 November 2008

Thymine-metal ion interactions: relevance for thymine quartet structures

scientific article published in April 2001

Tris is a non-innocent buffer during intein-mediated protein cleavage

scientific article published on 18 October 2007

Versatility in the mode of coordination [(C)−, (N,S), (C,N)− or (C,N,S)−] of the Schiff base: C6H5–CHN–CH2–CH2–SEt to palladium(II). X-ray crystal structures of cis-[Pd{C6H5–CHN–CH2–CH2–SEt}Cl2] and [Pd{C6H4–CHN–CH2

X-ray crystallographic study of several 2'-deoxy-beta-D-ribonucleosides with 1-deazapurine-derived aglycones

scientific article published on 13 November 2007

[(1-Methylcytosine)2H]I, an asymmetric base pair

[(Ethylenediamine)Pt(uracilate)](4), a Metal Analogue of Calix[4]arene. Coordination and Anion Host-Guest Chemistry Related to Its Conformational Dynamics

scientific article

trans-a2Pt(II) (a=NH3, CH3NH2) modified purine base pairs and triples: Hydrogen bonding between self-complementary pairs and triples and heterometal (Ag+) coordination leading to a 1 D helix

List of works by Eva Freisinger

(Z)-2-Phenyl-3-pivaloyl-1,1-dipropyl-guanidine.

A Family of Hydrazone-Based Nucleosides for Use in Metal-Mediated Base Pairs

Affinity of the Iminooxo Tautomer Anion of 1-Methylcytosine intrans-[Pt(NH3)2(1-MeC-N4)2]2+ for Heterometals

An optimized intein-mediated protein ligation approach for the efficient cyclization of cysteine-rich proteins

Analogues of Cis- and Transplatin with a Rich Solution Chemistry: cis-[PtCl2 (NH3 )(1-MeC-N3)] and trans-[PtI2 (NH3 )(1-MeC-N3)].

Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction

Cadmium in Metallothioneins

Canonical and unconventional pairing schemes between bis(nucleobase) complexes of trans-a2PtII: artificial nucleobase quartets and C-H...N bonds

Celebrating Helmut Sigel.

Comparison of the surprising metal-ion-binding properties of 5- and 6-uracilmethylphosphonate (5Umpa2- and 6Umpa2-) in aqueous solution and crystal structures of the dimethyl and di(isopropyl) esters of H2(6Umpa).

Connectivity patterns and rotamer states of nucleobases determine acid–base properties of metalated purine quartets

Different Behavior of the Histidine Residue toward Cadmium and Zinc in a Cadmium-Specific Metallothionein from an Aquatic Fungus

Diplatinum(III) complexes with bridging 1-methylcytosinate ligands and variable axial ligands, including guanine nucleobases

Diplatinum(III) complexes with four bridging 1-methylcytosinato nucleobases derived from a mononuclear trans-(NH3)2PtII complex and CuII.

Discrete Molecular Squares {[(en)M(CN)]4}4+ Derived from [(en)M(CN)2] (M = PtII, PdII)

Effects of N7-methylation, N7-platination, and C8-hydroxylation of guanine on H-bond formation with cytosine: platinum coordination strengthens the Watson-Crick pair

Exocyclic oxygen atoms of platinated nucleobases as binding sites for alkali metal ions †

From nucleotides to ribozymes—A comparison of their metal ion binding properties

From simple trans-[a2Pt(2-hydroxypyrimidine)2]2+ (a = NH3, CH3NH2) complexes to structures of higher complexity. Molecular recognition of 2-aminopyrimidine by hydrogen bond formation and reactivity toward additional metal ions

Further insights into the metal ion binding abilities and the metalation pathway of a plant metallothionein from Musa acuminata

Hydrogen bonding patterns of 7,9-dimethylguanine and its transplatinum(II) complexes

Hydrogen bonding patterns of N(7) platinated guanine: Watson–Crick and different self-pairing motifs in a tris(9-methylguanine) complex of PtII †

Impact of naturally occurring serine/cysteine variations on the structure and function of Pseudomonas metallothioneins

Incorporation of sulfide ions into the cadmium(II) thiolate cluster of Cicer arietinum metallothionein2.

Inter- and intra-molecular condensation patterns of (en)PdII with trans-[a2PtL2]2+ (a = am(m)ine, L = 2-aminopyridine): PtPd3 and Pt2Pd4 species with multiple amide bridges. Unexpected trapping of a pair of nitrate ions by a Pt2Pd4 double coneElectro

Interaction of Pt(II) and Pd(II) complexes of terpyridine with 1-methylazoles: A combined experimental and density functional study

Investigating the influence of histidine residues on the metal ion binding ability of the wheat metallothionein γ-Ec-1 domain

Lesion (in)tolerance reveals insights into DNA replication fidelity

Localization and Spectroscopic Analysis of the Cu(I) Binding Site in Wheat Metallothionein Ec-1

Metal ion binding properties of Triticum [corrected] aestivum Ec-1 metallothionein: evidence supporting two separate metal thiolate clusters

Metal ion binding properties of Triticum aestivum Ec-1 metallothionein: evidence supporting two separate metal thiolate clusters

Metal ion release from metallothioneins: proteolysis as an alternative to oxidation

Metal-modified nucleobase pairs and triplets as cytosine receptors

Metal-modified nucleobase sextet: joining four linear metal fragments (trans-a2PtII) and six model nucleobases to an exceedingly stable entity.

Metal-stabilized rare tautomers of nucleobases. 8. Promotion of rare cytosine tautomer upon complex formation with (dien)M2+ (M=Pt, Pd)

Metalated Nucleobase Quartets: Dimerization of a Metal-Modified Guanine, Cytosine Pair oftrans-(NH3)2PtIIand Formation of CH···N Hydrogen Bonds

Mixed-metal (platinum, palladium), mixed-pyrimidine (uracil, cytosine) self-assembling metallacalix[n]arenes: dynamic combinatorial chemistry with nucleobases and metal species

Molecular Architecture Based on Metal Triangles Derived from 2,2‘-Bipyrazine (Bpz) and EnMII(M = Pt, Pd)

N-Methyl-2, 2'-Dipicolylamine Complexes as Potential Models for Metal-Mediated Base Pairs

N1 and N3 linkage isomers of neutral and deprotonated cytosine with trans-[(CH3NH2)2PtII.

NMR spectroscopy in bioinorganic chemistry

On the interrelationship of mu-OH bridged dimers, trimers, and tetramers of (en)PtII and their Ag+ adducts

Oxidation of the N-terminal domain of the wheat metallothionein Ec -1 leads to the formation of three distinct disulfide bridges

Pd(II) and Pt(II) (R,S)-3-aminopyrrolidine complexes. Reactions with 9-ethylguanine and study of their antiproliferative activity

Pd(II)- and Pt(II)-cimetidine complexes. Crystal structure of trans-[Pt(N,S-cimetidine)2]Cl2.12H2O

Plant MTs-long neglected members of the metallothionein superfamily

Preface

Preface for the JIB Special Issue for the 12th European Biological Inorganic Chemistry Conference (EuroBIC 12) in Zurich, Switzerland, August 24–28, 2014

Protein and metal cluster structure of the wheat metallothionein domain γ-E(c)-1: the second part of the puzzle

PtII Binding to N1 of Cytosine: Strengthening the Watson-Crick Pair with Guanine and yet Confining Its pH Existence Range

Pyrazine as a building block for molecular architectures with PtII.

Reactivity of an extremenly sterically crowded monofunctional Pt complex, [Pt(1-MeC-N3)3(H2O)]2+ (1-MeC=1-methylcytosine), toward model nucleobases and selectivity toward guanine in single- and double-stranded deoxyoligonucleotides

Self-assembly of palladium(II) and platinum(II) complexes of 2-hydroxypyrimidine to novel metallacalix[4]arenes. Receptor properties through multiple H-bonding interactions.

Sequence-Specific Post-Synthetic Oligonucleotide Labeling for Single-Molecule Fluorescence Applications

Sequence-specific generation of 1,N(6)-ethenoadenine and 3,N(4)-ethenocytosine in single-stranded unmodified DNA.

Site-Specific Dual-Color Labeling of Long RNAs

Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy.

Solution structure of the circular γ-domain analog from the wheat metallothionein E(c)-1

Stick, Flick, Click: DNA-guided Fluorescent Labeling of Long RNA for Single-molecule FRET

Structural features specific to plant metallothioneins ⬇️

Sulfide ions as modulators of metal-thiolate cluster size in a plant metallothionein

Supramolecular isomerism of 2,2'-bipyrazine complexes with cis-(NH(3))(2)Pt(II): ligand rotational state and sequential orientation determine the 3D shape of metallacycles

Synthetic Ways to Tris(nucleobase) Complexes Derived from cis-Diammineplatinum(II) and a Platinum(II) Complex Containing Four Different Ligands, Three of Which Are Nucleobases

The Bioinorganic Periodic Table

The Metal-Thiolate Clusters of Plant Metallothioneins ⬇️

The beta(E)-domain of wheat E(c)-1 metallothionein: a metal-binding domain with a distinctive structure

The major function of a metallothionein from the aquatic fungus Heliscus lugdunensis is cadmium detoxification

The plant metallothionein 2 from Cicer arietinum forms a single metal-thiolate cluster

The two distinctive metal ion binding domains of the wheat metallothionein Ec-1

Thymine-metal ion interactions: relevance for thymine quartet structures

Tris is a non-innocent buffer during intein-mediated protein cleavage

Versatility in the mode of coordination [(C)−, (N,S), (C,N)− or (C,N,S)−] of the Schiff base: C6H5–CHN–CH2–CH2–SEt to palladium(II). X-ray crystal structures of cis-[Pd{C6H5–CHN–CH2–CH2–SEt}Cl2] and [Pd{C6H4–CHN–CH2

X-ray crystallographic study of several 2'-deoxy-beta-D-ribonucleosides with 1-deazapurine-derived aglycones

[(1-Methylcytosine)2H]I, an asymmetric base pair

[(Ethylenediamine)Pt(uracilate)](4), a Metal Analogue of Calix[4]arene. Coordination and Anion Host-Guest Chemistry Related to Its Conformational Dynamics

trans-a2Pt(II) (a=NH3, CH3NH2) modified purine base pairs and triples: Hydrogen bonding between self-complementary pairs and triples and heterometal (Ag+) coordination leading to a 1 D helix