List of works by Gary Lewin

A Molecular Signature of Myalgia in Myotonic Dystrophy 2

scientific article published on 14 March 2016

A Probabilistic Model for Estimating the Depth and Threshold Temperature of C-fiber Nociceptors.

scientific article published on 7 December 2015

A T-type calcium channel required for normal function of a mammalian mechanoreceptor

scientific article published in July 2003

A genetic basis for mechanosensory traits in humans

scientific article

A plethora of painful molecules

scientific article published in August 2004

A plethora of painful molecules [Curr. Opin. Neuro. 14 (2004) 443]

A role for BDNF in mechanosensation

scientific article published in May 1998

A role for T-type Ca2+ channels in mechanosensation

scientific article published on 13 June 2006

A somatosensory circuit for cooling perception in mice

scientific article published on 28 September 2014

A stomatin dimer modulates the activity of acid-sensing ion channels

scientific article

A stomatin-domain protein essential for touch sensation in the mouse

scientific article published on 13 December 2006

ASICs and mammalian mechanoreceptor function

scientific article published on 18 December 2014

Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P

scientific article

Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived Neurotrophic functions

scientific article published on October 1999

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

scientific article published on February 2014

Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli.

scientific article published on October 1993

An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors.

scientific article

An ultrastructural size principle

scientific article published on February 1994

BDNF but not NT-4 is required for normal flexion reflex plasticity and function

scientific article published on July 2001

BDNF overexpression induces differential increases among subsets of sympathetic innervation in murine back skin

scientific article published in October 1998

Cellular sources of enhanced brain-derived neurotrophic factor production in a mouse model of allergic inflammation

scientific article

Central hyperexcitability triggered by noxious inputs

scientific article

Chapter 13 Finding Sensory Neuron Mechanotransduction Components

Congenital deafness is associated with specific somatosensory deficits in adolescents

scientific article

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development

scientific article published on 26 March 2009

Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes

scientific article

Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons

scientific article

Dorsal Horn Plasticity Following Re-routeing of Peripheral Nerves: Evidence for Tissue-Specific Neurotrophic Influences from the Periphery

article

Erratum: Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

scholarly article published in Nature Neuroscience

Evidence for a protein tether involved in somatic touch

scientific article

Evolution. Natural selection and pain meet at a sodium channel

scientific article published in October 2013

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.

scientific article

Functional neurokinin and NMDA receptor activity in an animal naturally lacking substance P: the naked mole-rat

scientific article

Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain.

scientific article

GABA blocks pathological but not acute TRPV1 pain signals

scientific article

GFR alpha2/neurturin signalling regulates noxious heat transduction in isolectin B4-binding mouse sensory neurons

scientific article published on November 2002

Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System

scientific article published on 15 March 2017

Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization

scientific article

Hairy sensation

scientific article published on May 2013

Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors

scientific article

Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat

scientific article published on October 2016

Identification of caveolae-like structures on the surface of intact cells using scanning force microscopy

scientific article published in July 2003

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability

scientific article published in February 2018

In vivo effects of neurotrophin-3 during sensory neurogenesis

scientific article published on 01 January 1996

Increase of blood flow in skin and spinal cord following activation of small diameter primary afferents

scientific article

Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms

scientific article published on 23 March 2020

Inhibition of c-Kit signaling is associated with reduced heat and cold pain sensitivity in humans

scientific article published on 21 March 2014

Isolectin B(4)-positive and -negative nociceptors are functionally distinct.

scientific article published in August 1999

KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man.

scientific article published on 20 November 2011

Lack of neurotrophin-4 causes selective structural and chemical deficits in sympathetic ganglia and their preganglionic innervation.

scientific article published in May 2001

Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons

scientific article published on 3 July 2011

Lipidome determinants of maximal lifespan in mammals

scientific article

Maintenance of modality-specific connections in the spinal cord after neonatal nerve growth factor deprivation

scientific article published in August 1996

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects.

scientific article published in September 2016

Mechanoelectrical transduction in chondrocytes

scientific article published on 23 January 2018

Mechanosensation and pain

scientific article published in October 2004

Mechanosensitive currents in the neurites of cultured mouse sensory neurones.

scientific article published on 12 October 2006

Muscle afferents innervating skin form somatotopically appropriate connections in the adult rat dorsal horn

scientific article published in August 1993

NMDA receptors and activity-dependent tuning of the receptive fields of spinal cord neurons.

scientific article published in June 1994

Neonatal Anti-NGF Treatment Reduces the Aδ- and C-Fibre Evoked Vasodilator Responses in Rat Skin: Evidence That Nociceptor Afferents Mediate Antidromic Vasodilatation

article

Nerve growth factor and nociception.

scientific article

Nerve growth factor and nociception: from experimental embryology to new analgesic therapy.

scientific article published on January 2014

Nerve growth factor-induced hyperalgesia in the neonatal and adult rat

article

Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1

scientific article

Neurotrophin-3 involvement in the regulation of hair follicle morphogenesis

scientific article published in August 1998

Neurotrophin-4: a survival factor for adult sensory neurons

scientific article published in August 2002

Neurotrophins and the specification of neuronal phenotype

scientific article

Neurotrophins live or let die: does p75NTR decide?

scientific article published on February 1997

Neurotrophins, nociceptors and pain

scientific article published in October 2000

Neurotrophins: a link between airway inflammation and airway smooth muscle contractility in asthma?

scientific article published in February 1999

Nociceptive tuning by stem cell factor/c-Kit signaling

scientific article published in December 2007

Nociceptors: a phylogenetic view

scientific article published on 11 October 2009

On the role of nerve growth factor in the development of myelinated nociceptors

article

PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors

scientific article published on 3 December 2014

Peripheral and Central Mechanisms of NGF-induced Hyperalgesia

scientific article published on 01 December 1994

Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice

scientific article published on 7 March 2011

Peripheral sensitisation of nociceptors via G-protein-dependent potentiation of mechanotransduction currents

scientific article published on 8 June 2009

Photoswitchable fatty acids enable optical control of TRPV1.

scientific article published on 22 May 2015

Physiological properties of primary sensory neurons appropriately and inappropriately innervating skeletal muscle in adult rats

scientific article published on 01 October 1991

Physiological properties of primary sensory neurons appropriately and inappropriately innervating skin in the adult rat

scientific article published on 01 October 1991

Physiology of the neurotrophins

scientific article published on January 1996

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

scientific article

Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses.

scientific article published in August 1998

Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity

scientific article

Pro-neurotrophins, sortilin, and nociception

scientific article published on February 2014

Quantitative analysis of peptide levels and neurogenic extravasation following regeneration of afferents to appropriate and inappropriate targets.

scientific article published in January 1989

Rapid molecular evolution of pain insensitivity in multiple African rodents

scientific article published on 01 May 2019

Receptive properties of mouse sensory neurons innervating hairy skin

scientific article published on 01 October 1997

Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons

scientific article published on June 2012

Regulation of afferent connectivity in the adult spinal cord by nerve growth factor.

scientific article published in January 1992

Regulation of cutaneous C-fiber heat nociceptors by nerve growth factor in the developing rat

scientific article published on 01 March 1994

Regulation of myelinated nociceptor function by nerve growth factor in neonatal and adult rats

scientific article published in January 1993

Removing constraints on neural sprouting

scientific article published on 01 May 1992

Role of T-Type Calcium Current in Identified D-Hair Mechanoreceptor Neurons Studied In Vitro

article

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

scientific article published on 14 October 2007

Roles of neurotrophin-3 during early development of the peripheral nervous system

article

Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin

scientific article

Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber)

scientific article published in January 2008

Sensory mechanotransduction at membrane-matrix interfaces

scientific article

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

scientific article

Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity

scientific article published on 12 December 2016

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

scientific article

Specialized mechanoreceptor systems in rodent glabrous skin

scientific article published on 15 September 2018

Specialized mechanoreceptor systems in rodent glabrous skin

Specific Subtypes of Cutaneous Mechanoreceptors Require Neurotrophin-3 Following Peripheral Target Innervation

scientific article published on 01 February 1996

Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of Bathyergidae

scientific article

Speed and temperature dependences of mechanotransduction in afferent fibers recorded from the mouse saphenous nerve.

scientific article published on 24 September 2008

Stability and plasticity of primary afferent projections following nerve regeneration and central degeneration

scientific article published on 01 February 1999

Stomatin and sensory neuron mechanotransduction.

scientific article published on 17 October 2007

Stomatin, a MEC-2 like protein, is expressed by mammalian sensory neurons

scientific article published on June 1999

Stomatin-domain protein interactions with acid-sensing ion channels modulate nociceptor mechanosensitivity

scientific article published on 19 August 2013

Stomatin-domain proteins

scientific article published on 17 April 2011

Stretching it for pain

scientific article published on 21 April 2008

Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1

scientific journal article

TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration

scientific article published on 31 March 2020

The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain

scientific article published on November 2004

The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord

scientific article published on 8 February 2018

The Cav3.2 T-type calcium channel regulates temporal coding in mouse mechanoreceptors

scientific article published on 28 February 2011

The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice

The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice

scientific journal article

The Sensory Coding of Warm Perception

scientific article published on 16 March 2020

The consequences of long-term topical capsaicin application in the rat

scientific article published on 01 March 1991

The high threshold mechanotransducer: a status report

scientific article

The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord

scientific journal article

The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.

scientific article published in December 2004

The mammalian sodium channel BNC1 is required for normal touch sensation

scientific journal article

The molecular and cellular identity of peripheral osmoreceptors.

scientific article

The molecular basis of acid insensitivity in the African naked mole-rat

scientific article

The sensory coding of warm perception: Supplementary Figures

article

The sensory mechanotransduction ion channel ASIC2 (acid sensitive ion channel 2) is regulated by neurotrophin availability

scientific article published in January 2005

The transcription factor c-Maf controls touch receptor development and function.

scientific article

Touch sensation requires the mechanically gated ion channel ELKIN1

scientific article published on 29 February 2024

TrkB and neurotrophin-4 are important for development and maintenance of sympathetic preganglionic neurons innervating the adrenal medulla.

scientific article published in September 1998

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

scientific article

USH2A is a Meissner's corpuscle protein necessary for normal vibration sensing in mice and humans

scientific article published on 07 December 2020

Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation.

scientific article

Voltage-gating of mechanosensitive PIEZO channels

Voltage gating of mechanosensitive PIEZO channels.

scientific article published on 15 March 2018

Water-induced finger wrinkles do not affect touch acuity or dexterity in handling wet objects

scientific article published in 2014

cGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons

scientific article published on 4 November 2002

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