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List of works by Harmit Singh Malik

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The centromere paradox: stable inheritance with rapidly evolving DNA.

scientific article
Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain

scientific article (publication date: 22 February 2005)
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

journal article from 'bioRxiv' published in 2020
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

scientific article
Phylogenomics of the nucleosome

scientific article published on November 2003
Rules of engagement: molecular insights from host-virus arms races

scientific article published on January 2012
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.

scientific article published on 26 January 2012
Major evolutionary transitions in centromere complexity.

scientific article published in September 2009
Poised for contagion: evolutionary origins of the infectious abilities of invertebrate retroviruses

scientific article published on September 2000
Guidelines for naming nonprimate APOBEC3 genes and proteins

scientific article
Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa

scientific article (publication date: December 2009)
Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.

scientific article
Antiretroelement activity of APOBEC3H was lost twice in recent human evolution

scientific article
A unified phylogeny-based nomenclature for histone variants

scientific article
Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses

scientific article (publication date: 17 August 2012)
Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9.

scientific article
Protein kinase R reveals an evolutionary model for defeating viral mimicry

scientific article
Conflict begets complexity: the evolution of centromeres

scientific article
Phylogenetic Analysis of Ribonuclease H Domains Suggests a Late, Chimeric Origin of LTR Retrotransposable Elements and Retroviruses

article
Modular evolution of the integrase domain in the Ty3/Gypsy class of LTR retrotransposons

scientific article published on June 1999
The evolutionary conundrum of pathogen mimicry

scientific article published on 06 October 2009
Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes

scientific article published on 20 March 2014
Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

scientific article
BIOSAFETY. Safeguarding gene drive experiments in the laboratory

scientific article
Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals

scientific article
Altered heterochromatin binding by a hybrid sterility protein in Drosophila sibling species

scientific article
Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein

scientific article
Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses.

scientific article
Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein

scientific article
Identification of the endonuclease domain encoded by R2 and other site-specific, non-long terminal repeat retrotransposable elements

scientific article
Paleovirology--modern consequences of ancient viruses

scientific article published in February 2010
Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects

scientific article
Multiple roles for heterochromatin protein 1 genes in Drosophila.

scientific article published on January 2009
Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila

scientific article
High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans

scientific article published on January 2006
Evolutionary specialization of the nuclear targeting apparatus

scientific journal article
Rapid evolution of PARP genes suggests a broad role for ADP-ribosylation in host-virus conflicts

scientific article
Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone

scientific article
The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions

scientific article
Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes

scientific article published on 11 July 2013
Centromeres: selfish drivers

scientific article published in May 2002
Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.

scientific article published on October 2012
Convergent evolution of escape from hepaciviral antagonism in primates

scientific article (publication date: 2012)
Paleovirology - ghosts and gifts of viruses past

scientific article (publication date: October 2011)
Stepwise evolution of essential centromere function in a Drosophila neogene

scientific article
Are retrotransposons long-term hitchhikers?

scientific article published in March 1998
The breadth of antiviral activity of Apobec3DE in chimpanzees has been driven by positive selection

scientific article published on 10 August 2011
An expanded clade of rodent Trim5 genes

scientific article published on 15 January 2009
Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis

scholarly article

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