List of works - J Lloberas

A beta-glucosidase gene (bgl3) from Streptomyces sp. strain QM-B814. Molecular cloning, nucleotide sequence, purification and characterization of the encoded enzyme, a new member of family 1 glycosyl hydrolases

scientific article published on July 1994

An ORF from Bacillus licheniformis encodes a putative DNA repressor

scientific article published on January 2000

Arginine Transport Is Impaired in C57Bl/6 Mouse Macrophages as a Result of a Deletion in the Promoter of Slc7a2 (CAT2), and Susceptibility to Leishmania Infection Is Reduced

scientific article published on 04 March 2013

Arginine and macrophage activation

scientific article published on 01 January 2012

Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages

scientific journal article

CREB and AP-1 activation regulates MKP-1 induction by LPS or M-CSF and their kinetics correlate with macrophage activation versus proliferation.

scientific article

Characterization of Trex1 induction by IFN-γ in murine macrophages.

scientific article published on 14 January 2011

Cyclophilin A is required for M-CSF-dependent macrophage proliferation.

scientific article

Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells

scientific journal article

Deacetylation of C/EBPβ is required for IL-4-induced arginase-1 expression in murine macrophages

scientific article published on 20 September 2012

Decorin reverses the repressive effect of autocrine-produced TGF-beta on mouse macrophage activation

scientific article published in May 2003

Dexamethasone enhances macrophage colony stimulating factor- and granulocyte macrophage colony stimulating factor-stimulated proliferation of bone marrow-derived macrophages

scientific article published in May 1998

Effect of aging on macrophage function.

scientific article

Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors

scientific article

From transcription to cell surface expression, the induction of MHC class II I-Aα by interferon-γ in macrophages is regulated at different levels

scientific article published on 01 March 2001

Glycoprotein E of bovine herpesvirus type 1 is involved in virus transmission by direct cell-to-cell spread

scientific article published in November 1996

Granulocyte macrophage--colony-stimulating factor-dependent proliferation is impaired in macrophages from senescence-accelerated mice.

scientific article

Homogeneous conjugation of peptides onto gold nanoparticles enhances macrophage response

scientific article

IFN- -mediated inhibition of MAPK phosphatase expression results in prolonged MAPK activity in response to M-CSF and inhibition of proliferation

scientific article published on 05 August 2008

IL-4 blocks M-CSF-dependent macrophage proliferation by inducing p21Waf1 in a STAT6-dependent way.

scientific article published in February 2009

Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance

scientific article

Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids

scientific article

Immunosenescence of macrophages: reduced MHC class II gene expression

scientific article

Inorganic nanoparticles and the immune system: detection, selective activation and tolerance

Interferon γ Induces the Expression of p21waf-1 and Arrests Macrophage Cell Cycle, Preventing Induction of Apoptosis

scientific article published on 01 July 1999

JNK1 Is Required for the Induction ofMkp1Expression in Macrophages during Proliferation and Lipopolysaccharide-dependent Activation

scientific article published in Journal of Biological Chemistry

Lipopolysaccharide up-regulates MHC class II expression on dendritic cells through an AP-1 enhancer without affecting the levels of CIITA.

scientific article published on May 2007

MKP-1: a critical phosphatase in the biology of macrophages controlling the switch between proliferation and activation

scientific article

MacrophAging: a cellular and molecular review.

scientific article

Macrophage activation: classical versus alternative

scientific article

Macrophage mitochondrial MFN2 (mitofusin 2) links immune stress and immune response through reactive oxygen species (ROS) production

scientific article published on 10 November 2020

Macrophage proinflammatory activation and deactivation: a question of balance

scientific article published on January 2010

Macrophages and Mitochondria: A Critical Interplay Between Metabolism, Signaling, and the Functional Activity

scientific article published on 4 January 2017

Macrophages require distinct arginine catabolism and transport systems for proliferation and for activation

scientific journal article

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

scientific journal article

Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology

scientific article

Molecular cloning, expression and nucleotide sequence of the endo-beta-1,3-1,4-D-glucanase gene from Bacillus licheniformis. Predictive structural analyses of the encoded polypeptide

scientific article published on April 1991

NBS1 is required for macrophage homeostasis and functional activity in mice

scientific article published on 31 August 2015

Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (bo,+AT) of rBAT

scientific article

Peptides conjugated to gold nanoparticles induce macrophage activation

scientific article published on 08 November 2008

Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1.

scientific article published on January 2004

Repression of I-Aβ Gene Expression by the Transcription Factor PU.1 ⬇️

scientific article published on October 13, 1995

Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5[Prime]-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug

scientific article

STAT1 regulates lipopolysaccharide- and TNF-alpha-dependent expression of transporter associated with antigen processing 1 and low molecular mass polypeptide 2 genes in macrophages by distinct mechanisms

scientific article published in July 2004

Selective roles of MAPKs during the macrophage response to IFN-gamma

scientific article published in April 2008

Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases

scientific article

Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains

scientific article

Telomere Shortening and Oxidative Stress in Aged Macrophages Results in Impaired STAT5a Phosphorylation

scientific article published on 15 July 2009

The exonuclease Trex1 restrains macrophage proinflammatory activation.

scientific article published on 11 November 2013

The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages.

scientific article

The locus control region of the MHC class II promoter acts as a repressor element, the activity of which is inhibited by CIITA.

scientific article

The response of secondary genes to lipopolysaccharides in macrophages depends on histone deacetylase and phosphorylation of C/EBPβ.

scientific article

The transcription factor PU.1 is involved in macrophage proliferation

scientific article

Two missense point mutations in different alleles in the 3-hydroxy-3-methylglutaryl coenzyme A lyase gene produce 3-hydroxy-3-methylglutaric aciduria in a French patient.

scientific article

p21(waf1/CIP1), a CDK inhibitor and a negative feedback system that controls macrophage activation.

scientific article published in March 2009

List of works by J Lloberas

A beta-glucosidase gene (bgl3) from Streptomyces sp. strain QM-B814. Molecular cloning, nucleotide sequence, purification and characterization of the encoded enzyme, a new member of family 1 glycosyl hydrolases

An ORF from Bacillus licheniformis encodes a putative DNA repressor

Arginine Transport Is Impaired in C57Bl/6 Mouse Macrophages as a Result of a Deletion in the Promoter of Slc7a2 (CAT2), and Susceptibility to Leishmania Infection Is Reduced

Arginine and macrophage activation

Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages

CREB and AP-1 activation regulates MKP-1 induction by LPS or M-CSF and their kinetics correlate with macrophage activation versus proliferation.

Characterization of Trex1 induction by IFN-γ in murine macrophages.

Cyclophilin A is required for M-CSF-dependent macrophage proliferation.

Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells

Deacetylation of C/EBPβ is required for IL-4-induced arginase-1 expression in murine macrophages

Decorin reverses the repressive effect of autocrine-produced TGF-beta on mouse macrophage activation

Dexamethasone enhances macrophage colony stimulating factor- and granulocyte macrophage colony stimulating factor-stimulated proliferation of bone marrow-derived macrophages

Effect of aging on macrophage function.

Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors

From transcription to cell surface expression, the induction of MHC class II I-Aα by interferon-γ in macrophages is regulated at different levels

Glycoprotein E of bovine herpesvirus type 1 is involved in virus transmission by direct cell-to-cell spread

Granulocyte macrophage--colony-stimulating factor-dependent proliferation is impaired in macrophages from senescence-accelerated mice.

Homogeneous conjugation of peptides onto gold nanoparticles enhances macrophage response

IFN- -mediated inhibition of MAPK phosphatase expression results in prolonged MAPK activity in response to M-CSF and inhibition of proliferation

IL-4 blocks M-CSF-dependent macrophage proliferation by inducing p21Waf1 in a STAT6-dependent way.

Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance

Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids

Immunosenescence of macrophages: reduced MHC class II gene expression

Inorganic nanoparticles and the immune system: detection, selective activation and tolerance

Interferon γ Induces the Expression of p21waf-1 and Arrests Macrophage Cell Cycle, Preventing Induction of Apoptosis

JNK1 Is Required for the Induction ofMkp1Expression in Macrophages during Proliferation and Lipopolysaccharide-dependent Activation

Lipopolysaccharide up-regulates MHC class II expression on dendritic cells through an AP-1 enhancer without affecting the levels of CIITA.

MKP-1: a critical phosphatase in the biology of macrophages controlling the switch between proliferation and activation

MacrophAging: a cellular and molecular review.

Macrophage activation: classical versus alternative

Macrophage mitochondrial MFN2 (mitofusin 2) links immune stress and immune response through reactive oxygen species (ROS) production

Macrophage proinflammatory activation and deactivation: a question of balance

Macrophages and Mitochondria: A Critical Interplay Between Metabolism, Signaling, and the Functional Activity

Macrophages require distinct arginine catabolism and transport systems for proliferation and for activation

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology

Molecular cloning, expression and nucleotide sequence of the endo-beta-1,3-1,4-D-glucanase gene from Bacillus licheniformis. Predictive structural analyses of the encoded polypeptide

NBS1 is required for macrophage homeostasis and functional activity in mice

Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (bo,+AT) of rBAT

Peptides conjugated to gold nanoparticles induce macrophage activation

Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1.

Repression of I-Aβ Gene Expression by the Transcription Factor PU.1 ⬇️

Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5[Prime]-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug

STAT1 regulates lipopolysaccharide- and TNF-alpha-dependent expression of transporter associated with antigen processing 1 and low molecular mass polypeptide 2 genes in macrophages by distinct mechanisms

Selective roles of MAPKs during the macrophage response to IFN-gamma

Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases

Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains

Telomere Shortening and Oxidative Stress in Aged Macrophages Results in Impaired STAT5a Phosphorylation

The exonuclease Trex1 restrains macrophage proinflammatory activation.

The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages.

The locus control region of the MHC class II promoter acts as a repressor element, the activity of which is inhibited by CIITA.

The response of secondary genes to lipopolysaccharides in macrophages depends on histone deacetylase and phosphorylation of C/EBPβ.

The transcription factor PU.1 is involved in macrophage proliferation

Two missense point mutations in different alleles in the 3-hydroxy-3-methylglutaryl coenzyme A lyase gene produce 3-hydroxy-3-methylglutaric aciduria in a French patient.

p21(waf1/CIP1), a CDK inhibitor and a negative feedback system that controls macrophage activation.