List of works by Jacob E Corn

A De Novo Protein Binding Pair By Computational Design and Directed Evolution

scientific article

A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation

scientific article published on 10 March 2020

Advances in genome editing through control of DNA repair pathways

scientific article published on 02 December 2019

Atlastins remodel the endoplasmic reticulum for selective autophagy

Automated electron-density sampling reveals widespread conformational polymorphism in proteins

scientific article

BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.

scientific article

Binding Mechanism of Metal⋅NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases

scientific article

Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3.

scientific article

CRISPR germline engineering--the community speaks

scientific article published on May 2015

CRISPR off-target detection with DISCOVER-seq

scientific article published on 20 April 2020

CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway

scientific article published on 27 July 2018

Co-opting CRISPR to deliver functional RNAs

scientific article

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.

scientific article

Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7.

scientific article

Crosstalk between primase subunits can act to regulate primer synthesis in trans.

scientific article published in November 2005

Decoding a chain letter for degradation

scientific article

Disabling Cas9 by an anti-CRISPR DNA mimic

scientific article

Disabling Cas9 by an anti-CRISPR DNA mimic

Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.

scientific article published on 25 September 2017

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.

scientific article published on 20 January 2016

FASTDXL: a generalized screen to trap disulfide-stabilized complexes for use in structural studies

scientific article

Flexibility and design: conformational heterogeneity along the evolutionary trajectory of a redesigned ubiquitin

Hotspot-centric de novo design of protein binders

scientific article

Identification of a DNA primase template tracking site redefines the geometry of primer synthesis

scientific article

In vitro-transcribed guide RNAs trigger an innate immune response via the RIG-I pathway

article

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA induces homology-directed DNA repair

article published in 2017

PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants

scientific article published on 02 March 2021

ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules

scientific article (publication date: 2011)

Rosetta in CAPRI rounds 13-19. ⬇️

scientific article published on November 2010

RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite

scientific article (publication date: 2011)

Sometimes you're the scooper, and sometimes you get scooped: How to turn both into something good

scientific article published on 16 July 2018

Structure, Stability, and Folding of Ribonuclease H1 from the Moderately Thermophilic Chlorobium tepidum : Comparison with Thermophilic and Mesophilic Homologues

scientific article

Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs

scientific article published on 01 June 2020

Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering

scientific article published on 2 May 2017

THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves

scientific article

The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells

The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells

scientific article published on 11 July 2019

The RosettaCon 2012 Special Collection: Code Writ on Water, Documentation Writ in Stone

scientific article

Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair

scientific article published on 30 April 2020

USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria

scientific article

Ubiquitin in inflammation: the right linkage makes all the difference

scientific article published on April 2014

Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq

scientific article

Using protein motion to read, write, and erase ubiquitin signals

scientific article

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