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List of works by Yongqun He

A 2012 Workshop: Vaccine and Drug Ontology in the Study of Mechanism and Effect (VDOSME 2012).

scientific article published on 18 December 2012

A 2013 workshop: vaccine and drug ontology studies (VDOS 2013).

scientific article published on 20 March 2014

A 2018 workshop: vaccine and drug ontology studies (VDOS 2018)

scientific article published on 23 December 2019

A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: Guidelines from the Kidney Precision Medicine Project

scientific article published on 16 November 2020

A domain ontology for the Non-Coding RNA field

A genome-wide MeSH-based literature mining system predicts implicit gene-to-gene relationships and networks

scientific article

A statistical analysis of vaccine-adverse event data

scientific article published on 28 May 2019

Analyses of Brucella Pathogenesis, Host Immunity, and Vaccine Targets using Systems Biology and Bioinformatics

scientific article published on January 1, 2012

Analysis of Individual Differences in Vaccine Pharmacovigilance Using VAERS Data and MedDRA System Organ Classes: A Use Case Study With Trivalent Influenza Vaccine

scientific article

Anatomical Structures, Cell Types, and Biomarkers Tables Plus 3D Reference Organs in Support of a Human Reference Atlas

scholarly article published 1 June 2021

Anatomical structures, cell types and biomarkers of the Human Reference Atlas

scientific article published on 08 November 2021

Antibiotic Resistance Determinant-Focused Acinetobacter baumannii Vaccine Designed Using Reverse Vaccinology

scientific article published on 21 February 2017

Architecture and usability of OntoKeeper, an ontology evaluation tool

scientific article published on 08 August 2019

BBP: Brucella genome annotation with literature mining and curation

scientific article published on 16 July 2006

BN+1 Bayesian network expansion for identifying molecular pathway elements

scientific article published on November 2010

Bayesian network analysis of multi-compartmentalized immune responses in a murine model of sepsis and direct lung injury

scientific article published on 30 September 2015

Bayesian network expansion identifies new ROS and biofilm regulators

scientific article

Bioinformatics analysis of Brucella vaccines and vaccine targets using VIOLIN

scientific article

Brucella abortus RB51: enhancing vaccine efficacy and developing multivalent vaccines

article

Brucella abortus strain RB51 as a vector for heterologous protein expression and induction of specific Th1 type immune responses

scientific article

Brucella melitensis triggers time-dependent modulation of apoptosis and down-regulation of mitochondrion-associated gene expression in mouse macrophages.

scientific article published on September 2006

Brucellosis Ontology (IDOBRU) as an extension of the Infectious Disease Ontology

scientific article published on 31 October 2011

CIDO ontology updates and secondary analysis of host responses to COVID-19 infection based on ImmPort reports and literature

scientific article published on 28 August 2021

CIDO, a community-based ontology for coronavirus disease knowledge and data integration, sharing, and analysis

scientific article published on 12 June 2020

CLO: The cell line ontology

scientific article

COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning

scientific article published on 03 July 2020

COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning

scientific article (preprint)

CRCView: a web server for analyzing and visualizing microarray gene expression data using model-based clustering

scientific article

Caspase-2 mediated apoptotic and necrotic murine macrophage cell death induced by rough Brucella abortus

scientific article

Caspase-2 mediates a Brucella abortus RB51-induced hybrid cell death having features of apoptosis and pyroptosis

scientific article published on 27 November 2013

Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection

scientific article

Cells in ExperimentaL Life Sciences (CELLS-2018): capturing the knowledge of normal and diseased cells with ontologies.

scientific article published on 25 April 2019

Cells in experimental life sciences - challenges and solution to the rapid evolution of knowledge

scientific article

Characterization of recombinant B. abortus strain RB51SOD toward understanding the uncorrelated innate and adaptive immune responses induced by RB51SOD compared to its parent vaccine strain RB51

scientific article

Community-based Ontology Development, Annotation and Discussion with MediaWiki extension Ontokiwi and Ontokiwi-based Ontobedia

scientific article

Comparison, alignment, and synchronization of cell line information between CLO and EFO.

scientific article

Complementation of Brucella abortus RB51 with a functional wboA gene results in O-antigen synthesis and enhanced vaccine efficacy but no change in rough phenotype and attenuation

scientific article

Complete genome sequence of Brucella melitensis biovar 3 strain NI, isolated from an aborted bovine fetus

scientific article

Computational Design of SARS-CoV-2 Spike Glycoproteins to Increase Immunogenicity by T Cell Epitope Engineering

scientific article published on 31 December 2020

Computational vaccinology and the ICoVax 2012 workshop

scientific article published on 8 March 2013

Conservation in gene encoding Mycobacterium tuberculosis antigen Rv2660 and a high predicted population coverage of H56 multistage vaccine in South Africa.

scientific article

Cov19VaxKB: A Web-based Integrative COVID-19 Vaccine Knowledge Base

scientific article published on 28 December 2021

Cwp22, a novel peptidoglycan cross-linking enzyme, plays pleiotropic roles in Clostridioides difficile

scientific article published on 28 June 2019

DNAVaxDB: the first web-based DNA vaccine database and its data analysis.

scientific article

Databases and in silico tools for vaccine design

scientific article published on January 2013

Development and application of an interaction network ontology for literature mining of vaccine-associated gene-gene interactions

scientific article

Differential Adverse Event Profiles Associated with BCG as a Preventive Tuberculosis Vaccine or Therapeutic Bladder Cancer Vaccine Identified by Comparative Ontology-Based VAERS and Literature Meta-Analysis

scientific article

Emerging vaccine informatics

scientific article

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage

scientific article

Environmental Temperature Differentially Modulates C. elegans Longevity through a Thermosensitive TRP Channel

scientific article published on 28 May 2015

Epitope promiscuity and population coverage of Mycobacterium tuberculosis protein antigens in current subunit vaccines under development

scientific article published on 08 January 2020

Finding our way through phenotypes

scientific article

Gene Ontology annotations and resources

scientific article

Genome Sequence of an Environmental Isolate of the Bacterial Pathogen Legionella pneumophila

scientific article published on 27 June 2013

Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology

scientific article

Group XV phospholipase A₂, a lysosomal phospholipase A₂.

scientific article

ICEO, a biological ontology for representing and analyzing bacterial integrative and conjugative elements

scientific article published on 20 January 2022

ICoVax 2013: the 3rd ISV Pre-conference Computational Vaccinology Workshop

scientific article published on 19 March 2014

Identification of New Features from Known Bacterial Protective Vaccine Antigens Enhances Rational Vaccine Design

scientific article published on 26 October 2017

Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

scientific article published on 20 December 2012

Improvement of PubMed Literature Searching using Biomedical Ontology

scientific article published on 28 July 2009

Induction of specific cytotoxic lymphocytes in mice vaccinated with Brucella abortus RB51.

scientific article

Integrative representations and analyses of vaccine-induced intended protective immunity and unintended adverse events using ontology-based and theory-guided approaches

scientific article published on 23 May 2016

Linguistic scope-based and biological event-based speculation and negation annotations in the BioScope and Genia Event corpora

scientific article (publication date: 6 October 2011)

Linking MedDRA(®)-Coded Clinical Phenotypes to Biological Mechanisms by the Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors.

scientific article published on 22 March 2016

Literature Mining and Ontology based Analysis of Host-Brucella Gene-Gene Interaction Network

scientific article

Literature-based discovery of IFN-gamma and vaccine-mediated gene interaction networks

scientific article

Machine learning-based identification and rule-based normalization of adverse drug reactions in drug labels

scientific article published on 23 December 2019

Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates

scientific article

Microbial modulation of host apoptosis and pyroptosis

scientific article published on 19 June 2014

Mining of vaccine-associated IFN-γ gene interaction networks using the Vaccine Ontology

scientific article

Modeling biomedical experimental processes with OBI

scientific article

Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project

scientific article published on 16 September 2020

Molecular targets for rapid identification of Brucella spp.

scientific article published on 22 February 2006

Network-based analysis of vaccine-related associations reveals consistent knowledge with the vaccine ontology.

scientific article

Novel Immunoprotective Proteins of Streptococcus pneumoniae Identified by Opsonophagocytosis Killing Screen

scientific article published on 22 August 2018

OAE: The Ontology of Adverse Events

scientific article

ODAE: Ontology-based systematic representation and analysis of drug adverse events and its usage in study of adverse events given different patient age and disease conditions.

scientific article published in May 2019

OHMI: the ontology of host-microbiome interactions

scientific article published on 30 December 2019

OSCI: standardized stem cell ontology representation and use cases for stem cell investigation.

scientific article published on 25 April 2019

OntoFox: web-based support for ontology reuse

scientific article

OntoPlot: A Novel Visualisation for Non-hierarchical Associations in Large Ontologies

scientific article published on 22 August 2019

Ontobee: A linked ontology data server to support ontology term dereferencing, linkage, query and integration

scientific article (publication date: 12 October 2016)

Ontodog: a web-based ontology community view generation tool

scientific article published on 09 January 2014

Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection

scientific article published on 13 January 2021

Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses.

scientific article published on 21 December 2017

Ontology representation and analysis of vaccine formulation and administration and their effects on vaccine immune responses

scientific article published on 20 December 2012

Ontology-Based Meta-Analysis of Animal and Human Adverse Events Associated With Licensed Brucellosis Vaccines.

scientific article published on 15 May 2018

Ontology-Based Vaccine Adverse Event Representation and Analysis.

scientific article published in January 2017

Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network.

scientific article

Ontology-based Vaccine and Drug Adverse Event Representation and Theory-guided Systematic Causal Network Analysis toward Integrative Pharmacovigilance Research

scientific article published on 11 March 2016

Ontology-based collection, representation and analysis of drug-associated neuropathy adverse events

scientific article (publication date: 2016)

Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines

scientific article

Ontology-based literature mining and class effect analysis of adverse drug reactions associated with neuropathy-inducing drugs.

scientific article

Ontology-based literature mining of E. coli vaccine-associated gene interaction networks.

scientific article published on 14 March 2017

Ontology-based representation and analysis of host-Brucella interactions

scientific article

Ontology-based systematic representation and analysis of traditional Chinese drugs against rheumatism.

scientific article published on 21 December 2017

Ontology-based systematical representation and drug class effect analysis of package insert-reported adverse events associated with cardiovascular drugs used in China

scientific article published on 23 October 2017

Ontology-based taxonomical analysis of experimentally verified natural and laboratory human coronavirus hosts and its implication for COVID-19 virus origination and transmission

scientific article published on 22 January 2024

Ontology-based time information representation of vaccine adverse events in VAERS for temporal analysis

scientific article published on 20 December 2012

Ontology-supported research on vaccine efficacy, safety and integrative biological networks

scientific article

Ontorat: automatic generation of new ontology terms, annotations, and axioms based on ontology design patterns

scientific article

Overexpression of protective antigen as a novel approach to enhance vaccine efficacy of Brucella abortus strain RB51

scientific article

PHIDIAS: a pathogen-host interaction data integration and analysis system

scientific article

PIML: the Pathogen Information Markup Language

scientific article published on 05 August 2004

Pathobiology and management of laboratory rodents administered CDC category A agents.

scientific article published on February 2007

Perform Pathway Enrichment Analysis Using ReactomeFIViz

scientific article published on 01 January 2020

Presence of putative repeat-in-toxin gene tosA in Escherichia coli predicts successful colonization of the urinary tract

scientific article

Proinflammatory caspase-2-mediated macrophage cell death induced by a rough attenuated Brucella suis strain

scientific article published on 4 April 2011

Protegen: a web-based protective antigen database and analysis system

scientific article

RNA-seq reveals the critical role of OtpR in regulating Brucella melitensis metabolism and virulence under acidic stress

scientific article

Rational Design of SARS-CoV-2 Spike Glycoproteins To Increase Immunogenicity By T Cell Epitope Engineering

scientific article published on 14 August 2020

Rationale and design of the Kidney Precision Medicine Project

scientific article published on 23 February 2021

Recombinant Ochrobactrum anthropi expressing Brucella abortus Cu,Zn superoxide dismutase protects mice against B. abortus infection only after switching of immune responses to Th1 type

scientific article

Safety and immunogenicity of mammalian cell derived and Modified Vaccinia Ankara vectored African swine fever subunit antigens in swine.

scientific article

Standardization of assay representation in the Ontology for Biomedical Investigations

scientific article published on 16 June 2021

Statistical and Ontological Analysis of Adverse Events Associated with Monovalent and Combination Vaccines against Hepatitis A and B Diseases

scientific article published on 03 October 2016

Strong antibody responses induced by protein antigens conjugated onto the surface of lecithin-based nanoparticles

scientific article published on September 2009

Systematic annotation and analysis of "virmugens"-virulence factors whose mutants can be used as live attenuated vaccines

scientific article published on 6 December 2012

Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence.

scientific article published on 27 October 2016

Systems biology and bioinformatics help decipher Brucella antigens involved in clinical manifestation of the disease

scientific article published on 21 March 2012

TCDO: A Community-Based Ontology for Integrative Representation and Analysis of Traditional Chinese Drugs and Their Properties

scientific article published on 23 September 2021

The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability

scientific article

The Human Phenotype Ontology in 2021

scientific article published on 02 December 2020

The Human Phenotype Ontology in 2024: phenotypes around the world

scientific article published in 2023

The Interaction Network Ontology-supported modeling and mining of complex interactions represented with multiple keywords in biomedical literature

scientific article published on 19 December 2016

The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology

scientific article

The Ontology for Biomedical Investigations

scientific article

The Ontology of Biological and Clinical Statistics (OBCS) for standardized and reproducible statistical analysis

scientific article

The Ontology of Biological and Clinical Statistics (OBCS)-based statistical method standardization and meta-analysis of host responses to yellow fever vaccines

article

The Ontology of Vaccine Adverse Events (OVAE) and its usage in representing and analyzing adverse events associated with US-licensed human vaccines

scientific article

The Web-Based DNA Vaccine Database DNAVaxDB and Its Usage for Rational DNA Vaccine Design.

scientific article

The cell line ontology-based representation, integration and analysis of cell lines used in China

scientific article published on 25 April 2019

The development of non-coding RNA ontology

scientific article published on January 2016

The eXtensible ontology development (XOD) principles and tool implementation to support ontology interoperability

scientific article published on 12 January 2018

The ontology of genetic susceptibility factors (OGSF) and its application in modeling genetic susceptibility to vaccine adverse events

scientific article (publication date: 2014)

Towards precision informatics of pharmacovigilance: OAE-CTCAE mapping and OAE-based representation and analysis of adverse events in patients treated with cancer drugs.

scientific article published in January 2017

Updates on the web-based VIOLIN vaccine database and analysis system

scientific article

Using epitope predictions to evaluate efficacy and population coverage of the Mtb72f vaccine for tuberculosis

scientific article

VICO: Ontology-based representation and integrative analysis of Vaccination Informed Consent forms

scientific article published on 19 April 2016

VIO: ontology classification and study of vaccine responses given various experimental and analytical conditions

scientific article published on 23 December 2019

VIOLIN: vaccine investigation and online information network

scientific article

VO: Vaccine Ontology

VO: Vaccine Ontology

VO: Vaccine Ontology

VO: Vaccine Ontology

VRprofile: gene-cluster-detection-based profiling of virulence and antibiotic resistance traits encoded within genome sequences of pathogenic bacteria.

scientific article published on 10 January 2017

Vaccine adjuvant informatics: from data integration and analysis to rational vaccine adjuvant design

scientific article

Vaccine and Drug Ontology Studies (VDOS 2014).

scientific article published on 25 February 2016

Vaccine informatics

scientific article published on January 2010

Vaxar: A Web-Based Database of Laboratory Animal Responses to Vaccinations and Its Application in the Meta-Analysis of Different Animal Responses to Tuberculosis Vaccinations

scientific article published on January 2016

Vaxign-ML: Supervised Machine Learning Reverse Vaccinology Model for Improved Prediction of Bacterial Protective Antigens

scientific article published on 25 February 2020

Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning

scientific article published on 01 July 2021

Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development

scientific article

VaximmutorDB: A Web-Based Vaccine Immune Factor Database and Its Application for Understanding Vaccine-Induced Immune Mechanisms

scientific article published on 12 March 2021

Vaxjo: a web-based vaccine adjuvant database and its application for analysis of vaccine adjuvants and their uses in vaccine development

scientific article

Vaxvec: The first web-based recombinant vaccine vector database and its data analysis

scientific article

Victors: a web-based knowledge base of virulence factors in human and animal pathogens

scientific article published in January 2019

miniTUBA: medical inference by network integration of temporal data using Bayesian analysis

scientific article