List of works by Susan Costantini

3D Modelling of Three Pro-Inflammatory Molecules in Selected Fish Species

scientific article published on 01 January 2010

A CD4 homologue in sea bass (Dicentrarchus labrax): molecular characterization and structural analysis

scientific article published on 9 April 2008

A Psychosocial Genomics Pilot Study in Oncology for Verifying Clinical, Inflammatory and Psychological Effects of Mind-Body Transformations-Therapy (MBT-T) in Breast Cancer Patients: Preliminary Results

scientific article published on 03 January 2021

A holistic approach to study the effects of natural antioxidants on inflammation and liver cancer

scientific article published on January 2014

A possible predictive marker of progression for hepatocellular carcinoma

scientific article

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells

scientific article published on 23 May 2013

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells.

scientific article published on 5 June 2014

Aflatoxin B1 and M1: Biological Properties and Their Involvement in Cancer Development.

scientific article published on 24 May 2018

Amino acid propensities for secondary structures are influenced by the protein structural class

scientific article

An approach for understanding the inflammation and cancer relationship

scientific article published on 20 August 2009

An overview of the sequence features of N- and C-terminal segments of the human chemokine receptors

scientific article published on 16 August 2014

Anti-Inflammatory Effects of a Methanol Extract from the Marine Sponge Geodia cydonium on the Human Breast Cancer MCF-7 Cell Line

scientific article

Ascorbic acid: its role in immune system and chronic inflammation diseases

scientific article published on May 2014

Assessment of the Selenoprotein M (SELM) over-expression on human hepatocellular carcinoma tissues by immunohistochemistry

scientific article

CDMS (Clinical Data Mining Software): a cytokinome data mining system for a predictive medicine of chronic inflammatory diseases

scientific article

CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not

scientific article published on 3 November 2014

Cancer biomarker profiling in patients with chronic hepatitis C virus, liver cirrhosis and hepatocellular carcinoma

scientific article published on 3 April 2013

Carotid intima-media thickness is predicted by combined eotaxin levels and severity of hepatic steatosis at ultrasonography in obese patients with Nonalcoholic Fatty Liver Disease

scientific article

Characterization and kinetics studies of water buffalo (Bubalus bubalis) myoglobin

Characterization and kinetics studies of water buffalo (Bubalus bubalis) myoglobin

scientific article published on 25 July 2006

Characterization of metalloproteinases, oxidative status and inflammation levels in the different stages of fibrosis in HCV patients

scientific article published on 16 February 2012

Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines

scientific article published on 2 January 2017

Common structural interactions between the receptors CXCR3, CXCR4 and CXCR7 complexed with their natural ligands, CXCL11 and CXCL12, by a modeling approach

scientific article published on 15 June 2013

Comparison of the seleno-transcriptome expression between human non-cancerous mammary epithelial cells and two human breast cancer cell lines

scientific article

Compositional patterns in the genomes of unicellular eukaryotes

scientific article

Computational Methods for Protein Fold Prediction: an Ab-initio Topological Approach

Conformational analysis of the human chemokine receptor CXCR3.

scientific article

Conformational diseases and structure-toxicity relationships: lessons from prion-derived peptides

scientific article published on February 2007

Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4.

scientific article

Cytokinome profile evaluation in patients with hepatitis C virus infection

scientific article

Cytokinome profile of patients with type 2 diabetes and/or chronic hepatitis C infection

scientific article

Deducing the functional characteristics of the human selenoprotein SELK from the structural properties of its intrinsically disordered C-terminal domain

scientific article published on 6 January 2016

Differential Response of Two Human Breast Cancer Cell Lines to the Phenolic Extract from Flaxseed Oil.

scientific article published on 08 March 2016

Dissimilar cytokine patterns in different human liver and colon cancer cell lines

scientific article published on 21 September 2013

Effects of Lipoic Acid, Caffeic Acid and a Synthesized Lipoyl-Caffeic Conjugate on Human Hepatoma Cell Lines

scientific article published on 27 July 2011

Evaluation of Aflatoxin M1 Effects on the Metabolomic and Cytokinomic Profiling of a Hepatoblastoma Cell Line

scientific article published on 28 October 2018

Evaluation of selenite effects on selenoproteins and cytokinome in human hepatoma cell lines.

scientific article published on 26 February 2013

Evaluation of the selenotranscriptome expression in two hepatocellular carcinoma cell lines.

scientific article published on 23 June 2015

Evaluation of the structural quality of modeled proteins by using globularity criteria

scientific article

Evolution of cell‐mediated immune defences: Cloning and structural characterisation of the T cell receptor beta chain from the icefish Chionodraco hamatus (Perciformes: Channichthyidae)

scientific article published in 2009

FASMA: a service to format and analyze sequences in multiple alignments

scientific article published on December 2007

Functional and structural features of adipokine family

scientific article published on 27 September 2012

Functional hypothesis on miraculin' sweetness by a molecular dynamics approach.

scientific article published on 6 May 2010

GPX4 and GPX7 over-expression in human hepatocellular carcinoma tissues

scientific article

Gene expression signature of human HepG2 cell line.

scientific article published on 26 January 2013

Genealogy of an ancient protein family: the Sirtuins, a family of disordered members

scientific article

Has selenium a chemopreventive effect on hepatocellular carcinoma?

scientific article published on June 2011

Human Prion Protein Helices: Studying Their Stability by Molecular Dynamics Simulations (SUPPLEMENTARY MATERIAL)

article

Human lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivity

scientific article published on 29 February 2016

Human sirt-1: molecular modeling and structure-function relationships of an unordered protein

scientific article

Inhibiting Monocyte Recruitment to Prevent the Pro-Tumoral Activity of Tumor-Associated Macrophages in Chondrosarcoma

scientific article published on 24 April 2020

Interactomic and pharmacological insights on human sirt-1

scientific article published in 2012

Interleukin-10 expression by real-time PCR and homology modelling analysis in the European sea bass (Dicentrarchus Labrax L.)

Intestinal T cell responses to gluten peptides are largely heterogeneous: implications for a peptide-based therapy in celiac disease

scientific article published in April 2009

Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles

scientific article published on 01 November 2015

Invariant Ser211 is involved in the catalysis of PD-L4, type I RIP from Phytolacca dioica leaves

scientific article published on 01 April 2007

Is serum Interleukin-17 associated with early atherosclerosis in obese patients?

scientific article

Modeling of the bacterial mechanism of methicillin-resistance by a systems biology approach

scientific article

Modeling the 3D structure of wheat subtilisin/chymotrypsin inhibitor (WSCI). Probing the reactive site with two susceptible proteinases by time-course analysis and molecular dynamics simulations

scientific article

Modelling of HLA-DQ2 and its interaction with gluten peptides to explain molecular recognition in celiac disease

scientific article

Modelling of fish interleukin-1 and its receptor.

scientific article published in May 2004

Modelling of the membrane receptor CXCR3 and its complexes with CXCL9, CXCL10 and CXCL11 chemokines: putative target for new drug design

scientific article published in October 2009

Molecular characterisation and structural analysis of an interferon homologue in sea bass (Dicentrarchus labrax L.).

scientific article published on 25 October 2008

Molecular cloning, differential expression and 3D structural analysis of the MHC class-II beta chain from sea bass (Dicentrarchus labrax L.).

scientific article

Molecular diagnostics and personalized medicine in oncology: Challenges and opportunities

scientific article published on 01 March 2013

Molecular modelling of co-receptor CD8αα and its complex with MHC class I and T-cell receptor in sea bream (Sparus aurata)

scientific article published on 07 April 2008

Molecular modelling of miraculin: Structural analyses and functional hypotheses.

scientific article published on 26 December 2007

N-terminal region of human chemokine receptor CXCR3: Structural analysis of CXCR3(1–48) by experimental and computational studies

article

New Prognostic and Predictive Markers in Cancer Progression

scientific article published on 17 November 2020

Peptide Folding Problem: A Molecular Dynamics Study on Polyalanines Using Different Force Fields

article

Peptides targeting chemokine receptor CXCR4: structural behavior and biological binding studies

scientific article published on 28 January 2014

Phytochemical profile of Juniperus oxycedrus ssp. oxycedrus berries: A new monoterpene glucoside and evaluation of the effects on cancer cell lines

Polysaccharides from the Marine Environment with Pharmacological, Cosmeceutical and Nutraceutical Potential

scientific article

Potential Anticancer Effects of Polyphenols from Chestnut Shell Extracts: Modulation of Cell Growth, and Cytokinomic and Metabolomic Profiles

scientific article published on 21 October 2016

Potential anti-inflammatory effects of the hydrophilic fraction of pomegranate (Punica granatum L.) seed oil on breast cancer cell lines

scientific article

PreSSAPro: a software for the prediction of secondary structure by amino acid properties

scientific article

Prediction of the protein structural class by specific peptide frequencies

scientific article published on 10 October 2008

Redesigning the reactive site loop of the wheat subtilisin/chymotrypsin inhibitor (WSCI) by site-directed mutagenesis. A protein-protein interaction study by affinity chromatography and molecular modeling

scientific article published on 16 June 2009

Regulatory T cells, interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), CXCL10, CXCL11, epidermal growth factor (EGF) and hepatocyte growth factor (HGF) as surrogate markers of host immunity in patients with renal cell carcinoma

scientific article published on 15 March 2013

Serum cytokine levels as putative prognostic markers in the progression of chronic HCV hepatitis to cirrhosis

scientific article published on 17 November 2010

Serum cytokine levels in patients with hepatocellular carcinoma

scientific article

Simulation of conformational changes occurring when a protein interacts with its receptor

scientific article published on 30 March 2007

Simultaneous evaluation of the circulating levels of both Th1 and Th2 chemokines in patients with autoimmune Addison's disease

scientific article published on 15 December 2010

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

scientific article

Structural and functional similarities between osmotin from Nicotiana tabacum seeds and human adiponectin

scientific article

Structural and functional studies of the human selenium binding protein-1 and its involvement in hepatocellular carcinoma

scientific article published on 19 February 2011

Structural characterization and comparative modeling of PD-Ls 1-3, type 1 ribosome-inactivating proteins from summer leaves of Phytolacca dioica L.

scientific article published on 26 October 2008

Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain?

scientific article published on 5 June 2017

Structure-fluctuation-function relationships of seven pro-angiogenic isoforms of VEGFA, important mediators of tumorigenesis

scientific article published on 21 January 2015

Structure-function relationship and evolutionary history of the human selenoprotein M (SelM) found over-expressed in hepatocellular carcinoma

scientific article published on 9 December 2013

Synergistic antitumor effect of Doxorubicin and tacrolimus (FK506) on hepatocellular carcinoma cell lines

scientific article published on 20 February 2014

T cell receptor beta chain from sea bream (Sparus aurata): molecular cloning, expression and modelling of the complexes with MHC class I.

scientific article

Targeting EphA2-Sam and Its Interactome: Design and Evaluation of Helical Peptides Enriched in Charged Residues

scientific article published on 20 October 2016

Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment ⬇️

scientific article published on November 3, 2010

The CD8alpha from sea bass (Dicentrarchus labrax L.): Cloning, expression and 3D modelling

scientific article

The Cytokinome Profile in Patients with Hepatocellular Carcinoma and Type 2 Diabetes

scientific article

The Effect of Light Exposure at Night (LAN) on Carcinogenesis via Decreased Nocturnal Melatonin Synthesis

scientific article published on 29 May 2018

The N-terminal 1-16 peptide derived in vivo from protein seminal vesicle protein IV modulates alpha-thrombin activity: potential clinical implications

scientific article published on October 2008

The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis, and binding studies

scientific article published on 23 May 2012

The gene expression profiling of hepatocellular carcinoma by a network analysis approach shows a dominance of intrinsically disordered proteins (IDPs) between hub nodes.

scientific article published on 12 August 2015

The protein-protein interaction network of the human Sirtuin family

scientific article published on 28 June 2013

Transamidation of wheat flour inhibits the response to gliadin of intestinal T cells in celiac disease.

scientific article published on 20 June 2007

Understanding the role of the topology in protein folding by computational inverse folding experiments

scientific article published on 8 April 2008

Vitamin C effect on mitoxantrone-induced cytotoxicity in human breast cancer cell lines

scientific article

Wheat Subtilisin/Chymotrypsin Inhibitor (WSCI) as a scaffold for novel serine protease inhibitors with a given specificity.

scientific article published in October 2012

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