Search filters

List of works by Helmut Jonuleit

A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection

scientific article published in July 2001

A key role of GARP in the immune suppressive tumor microenvironment

scientific article

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

scientific article

Allergen-induced IgE-dependent gut inflammation in a human PBMC-engrafted murine model of allergy

scientific article published on 10 January 2012

Allergen-specific immune deviation from a TH2 to a TH1 response induced by dendritic cells and collagen type I

scientific article published on 01 November 1999

Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor 7.

scientific article published on 24 March 2017

Boosting regulatory T cell function by CD4 stimulation enters the clinic

scientific article published on 18 June 2012

CD4-mediated functional activation of human CD4+CD25+ regulatory T cells

scientific article published on 01 May 2007

CD4-mediated regulatory T-cell activation inhibits the development of disease in a humanized mouse model of allergic airway disease

article

CD40 signalling induces IL-10-producing, tolerogenic dendritic cells

scientific article published on 02 November 2009

Cladribine exerts an immunomodulatory effect on human and murine dendritic cells.

scientific article

Correction: Kinetics of IL-6 Production Defines T Effector Cell Responsiveness to Regulatory T Cells in Multiple Sclerosis.

scientific article

Costimulatory molecules on immunogenic versus tolerogenic human dendritic cells

scientific article published on 03 April 2013

Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression

scientific article

Cytokines and their effects on maturation, differentiation and migration of dendritic cells

scientific article published on December 1996

Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG.

scientific article published on 17 January 2006

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha

scientific article published on 29 May 2017

Dendritic cell-based immunotherapy of malignant melanoma: success and limitations

scientific article published on March 2007

Dendritic cells as a tool to induce anergic and regulatory T cells

scientific article

Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma

scientific article published on 01 November 1997

Dendritic cells: sentinels of immunity and tolerance

scientific article

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells

scientific article

Different efficiency of heat shock proteins (HSP) to activate human monocytes and dendritic cells: superiority of HSP60

scientific article published on 01 December 2002

Dimethyl Fumarate Therapy Significantly Improves the Responsiveness of T Cells in Multiple Sclerosis Patients for Immunoregulation by Regulatory T Cells

scientific article

Editorial: Current Concepts of Cellular and Biological Drugs to Modulate Regulatory T Cell Activity in the Clinic

scientific article published on 14 April 2016

Expression of the actin-bundling protein fascin in cultured human dendritic cells correlates with dendritic morphology and cell differentiation

scientific article published on 01 October 2000

FTY720 (fingolimod) treatment tips the balance towards less immunogenic antigen-presenting cells in patients with multiple sclerosis.

scientific article published on 2 March 2015

Fetal calf serum-free generation of functionally active murine dendritic cells suitable for in vivo therapeutic approaches

scientific article published on 01 January 2000

Fulfilling the dream: tolerogenic dendritic cells to treat multiple sclerosis

scientific article published on 01 March 2012

Functional and morphological characterization of 4F7+ spleen accessory dendritic cells

scientific article

GARP inhibits allergic airway inflammation in a humanized mouse model.

scientific article published on 15 March 2016

Generation of monoclonal antibodies against human regulatory T cells

scientific article published on 22 January 2010

Human CD(4+)CD(25+) regulatory T cells and infectious tolerance

scientific article published on January 2004

Human CD25+ regulatory T cells: two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells.

scientific article

Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function

scientific article

Human primary dendritic cell subsets differ in their IL-12 release in response to Leishmania major infection

scientific article published on 12 August 2010

Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

scientific article published on June 2001

IgG1 anti-epidermal growth factor receptor antibodies induce CD8-dependent antitumor activity

scientific article

Immature, but not inactive: the tolerogenic function of immature dendritic cells

scientific article

Immune regulation by dendritic cells and T cells--basic science, diagnostic, and clinical application.

scientific article published on January 2011

Immune regulation by regulatory T cells: implications for transplantation

scientific article

Immunization with a Synthetic Human MUC1 Glycopeptide Vaccine against Tumor-Associated MUC1 Breaks Tolerance in Human MUC1 Transgenic Mice

scientific article published on 4 July 2017

Increased regulatory T-cell frequencies in patients with advanced melanoma correlate with a generally impaired T-cell responsiveness and are restored after dendritic cell-based vaccination

scientific article published on 01 August 2010

Induction of IL-15 messenger RNA and protein in human blood-derived dendritic cells: a role for IL-15 in attraction of T cells

scientific article published on 01 March 1997

Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

scientific article published on November 2000

Induction of strong and persistent MelanA/MART-1-specific immune responses by adjuvant dendritic cell-based vaccination of stage II melanoma patients

scientific article published in May 2006

Induction of tolerance by IL-10-treated dendritic cells

scientific article published on 01 November 1997

Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

scientific article published on July 2002

Interaction of TLR2 and TLR4 ligands with the N-terminal domain of Gp96 amplifies innate and adaptive immune responses

scientific article published on 05 June 2006

Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells.

scientific article published on 17 July 2015

Interferon-α abrogates tolerance induction by human tolerogenic dendritic cells

scientific article

Kinetics of IL-6 production defines T effector cell responsiveness to regulatory T cells in multiple sclerosis

scientific article

Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network.

scientific article published on 16 February 2016

Large scale preparation of human MHC class II+ integrin β1+ Tregs

scientific article published on 25 June 2010

Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction.

scientific article

Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cells

scientific article published on 01 September 2000

Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis.

scientific article

Myeloid dendritic cell: From sentinel of immunity to key player of peripheral tolerance?

scientific article published on 13 February 2009

Novel Concept of CD4-Mediated Activation of Regulatory T Cells for the Treatment of Graft-Versus-Host Disease.

scientific article published on 8 November 2017

Oxymetazoline modulates proinflammatory cytokines and the T-cell stimulatory capacity of dendritic cells

scientific article published on 01 March 2007

Pillars Article: Induction of Tolerance by IL-10-Treated Dendritic Cells. J. Immunol. 1997. 159: 4772-4780.

scientific article

Plasmacytoid dendritic cells are inefficient in activation of human regulatory T cells

scientific article

Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: implications for an efficient vaccination strategy

scientific article published on February 2003

Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions

scientific article published on 01 December 1997

Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells.

scientific article published on 13 May 2009

Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.

scientific article

Regulatory T cells--the renaissance of the suppressor T cells.

scientific article published on January 2007

Regulatory T cells: present facts and future hopes.

scientific article

Research in practice: Regulatory T cells - targets for therapeutic approaches?

scientific article published on 07 September 2010

Soluble GARP has potent antiinflammatory and immunomodulatory impact on human CD4⁺ T cells

scientific article published in July 2013

Specific stabilization of the 4F7 molecule on dendritic cells by contact allergens

scientific article published on 01 November 1996

Subclinical CNS inflammation as response to a myelin antigen in humanized mice.

scientific article published on 3 May 2013

Synthesis of maleimide-functionalyzed HPMA-copolymers and in vitro characterization of the aRAGE- and human immunoglobulin (huIgG)-polymer conjugates

scientific article published on 13 December 2012

TCR signalling network organization at the immunological synapses of murine regulatory T cells

scientific article published on 17 August 2017

The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells

scientific article published in March 2009

Treg cells as potential cellular targets for functionalized nanoparticles in cancer therapy.

scientific article published on 21 September 2016

Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma

scientific article

miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression

scientific article