List of works - Torsten Schaller

Active site remodeling switches HIV specificity of antiretroviral TRIMCyp

scientific article

An active TRIM5 protein in rabbits indicates a common antiviral ancestor for mammalian TRIM5 proteins.

scientific article published on 29 August 2007

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes

scientific article (publication date: May 2007)

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

scientific article

Cyclophilin A levels dictate infection efficiency of human immunodeficiency virus type 1 capsid escape mutants A92E and G94D.

scientific article published on 10 December 2008

Development of a chemical probe against NUDT15

scientific article published on 20 July 2020

Effects of Inner Nuclear Membrane Proteins SUN1/UNC-84A and SUN2/UNC-84B on the Early Steps of HIV-1 Infection.

scientific article

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

scientific article

Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection

scientific article published on 25 February 2013

From structure to function: new insights into hepatitis C virus RNA replication

scientific article

Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses.

scientific article published on 3 July 2007

HIV Interplay with SAMHD1

scientific article published in Science

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2

scientific article

HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358

scientific article

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

scientific article

Hare TRIM5α restricts divergent retroviruses and exhibits significant sequence variation from closely related lagomorpha TRIM5 genes

scientific article

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

scientific article

Human MxB Protein Is a Pan-herpesvirus Restriction Factor

scientific article published on 16 August 2018

Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction

scientific article

Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor.

scientific article

Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion

scientific article

New insights into an X-traordinary viral protein

scientific article published in 2014

Nuclear import of SAMHD1 is mediated by a classical karyopherin α/β1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation

scientific article

Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5alpha proteins including human TRIM5alpha

scientific article published on March 2009

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

scientific article

Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy

scientific article published on 17 January 2020

SAMHD1 is a barrier to antimetabolite-based cancer therapies.

scientific article published on 3 February 2017

SAMHD1 protects cancer cells from various nucleoside-based antimetabolites

scientific article

Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo

scientific article published in August 2006

TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription.

scientific article

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies

scientific article

Truncation of TRIM5 in the Feliformia explains the absence of retroviral restriction in cells of the domestic cat

scientific article published on 03 June 2009

List of works by Torsten Schaller

Active site remodeling switches HIV specificity of antiretroviral TRIMCyp

An active TRIM5 protein in rabbits indicates a common antiviral ancestor for mammalian TRIM5 proteins.

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

Cyclophilin A levels dictate infection efficiency of human immunodeficiency virus type 1 capsid escape mutants A92E and G94D.

Development of a chemical probe against NUDT15

Effects of Inner Nuclear Membrane Proteins SUN1/UNC-84A and SUN2/UNC-84B on the Early Steps of HIV-1 Infection.

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection

From structure to function: new insights into hepatitis C virus RNA replication

Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses.

HIV Interplay with SAMHD1

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2

HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

Hare TRIM5α restricts divergent retroviruses and exhibits significant sequence variation from closely related lagomorpha TRIM5 genes

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

Human MxB Protein Is a Pan-herpesvirus Restriction Factor

Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction

Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor.

Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion

New insights into an X-traordinary viral protein

Nuclear import of SAMHD1 is mediated by a classical karyopherin α/β1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation

Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5alpha proteins including human TRIM5alpha

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy

SAMHD1 is a barrier to antimetabolite-based cancer therapies.

SAMHD1 protects cancer cells from various nucleoside-based antimetabolites

Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo

TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription.

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies

Truncation of TRIM5 in the Feliformia explains the absence of retroviral restriction in cells of the domestic cat