Search filters

List of works by Peter Timms

A 5-year Chlamydia vaccination programme could reverse disease-related koala population decline: predictions from a mathematical model using field data.

scientific article

A cohort study of Chlamydia trachomatis treatment failure in women: a study protocol

scientific article

A comparison of the effects of a chlamydial vaccine administered during or after a C. muridarum urogenital infection of female mice

scientific article published on 19 July 2011

A mathematical model for the investigation of the Th1 immune response to Chlamydia trachomatis.

scientific article published on March 2003

A multi-subunit chlamydial vaccine induces antibody and cell-mediated immunity in immunized koalas (Phascolarctos cinereus): comparison of three different adjuvants

scientific article published on February 2010

A transcriptome resource for the koala (Phascolarctos cinereus): insights into koala retrovirus transcription and sequence diversity

scientific article

Adaptation and conservation insights from the koala genome

scientific article published on 02 July 2018

An improved method for the transformation of Lactobacillus strains using electroporation

Analysis and Conservation Implications of Koala Genetics

article

Analysis of promoter sequences from Lactobacillus and Lactococcus and their activity in several Lactobacillus species

article

Anti-P. gingivalis response correlates with atherosclerosis

scientific article

Antigenic specificity of a monovalent versus polyvalent MOMP based Chlamydia pecorum vaccine in koalas (Phascolarctos cinereus).

scientific article published on 07 January 2013

Apoptosis is induced in Chlamydia trachomatis-infected HEp-2 cells by the addition of a combination innate immune activation compounds and the inhibitor wedelolactone.

scientific article published on 27 December 2010

Babesia bovis: Evidence for selection of subpopulations during attenuation

article

Babesia bovis: Molecular and biological characteristics of cloned parasite lines

scientific article published on 01 April 1987

Babesia bovis: Proteins of virulent and avirulent parasites passaged through ticks and splenectomized or intact calves

article

CD4+ T cells reduce the tissue burden of Chlamydia muridarum in male BALB/c mice

scientific article published on July 2010

CIDB: Chlamydia Interactive Database for cross-querying genomics, transcriptomics and proteomics data

scientific article

CTA1-DD is an effective adjuvant for targeting anti-chlamydial immunity to the murine genital mucosa.

scientific article published on 06 June 2009

Characterisation of enterovirus 71 replication kinetics in human colorectal cell line, HT29.

scientific article published on 18 June 2013

Characterization of in vitro Chlamydia muridarum persistence and utilization in an in vivo mouse model of Chlamydia vaccine.

scientific article published on 18 February 2013

Chlamydia

Chlamydia genomics: providing novel insights into chlamydial biology

scientific article published on 02 June 2014

Chlamydia muridarum infection-induced destruction of male germ cells and sertoli cells is partially prevented by Chlamydia major outer membrane protein-specific immune CD4 cells.

scientific article published on 03 December 2014

Chlamydia muridarum major outer membrane protein-specific antibodies inhibit in vitro infection but enhance pathology in vivo

scientific article published on February 2011

Chlamydia pneumoniae is genetically diverse in animals and appears to have crossed the host barrier to humans on (at least) two occasions

scientific article (publication date: May 2010)

Chlamydia pneumoniae: modern insights into an ancient pathogen

scientific article published on 05 December 2012

Chlamydia trachomatis infection: host immune responses and potential vaccines

scientific article published on 09 January 2008

Chlamydia trachomatis infection: incidence, health costs and prospects for vaccine development

scientific article

Chlamydia trachomatis responds to heat shock, penicillin induced persistence, and IFN-gamma persistence by altering levels of the extracytoplasmic stress response protease HtrA.

scientific article

Chlamydia trachomatis serovars among strains isolated from members of rural indigenous communities and urban populations in Australia

scientific article

Chlamydial persistence: beyond the biphasic paradigm

scientific article published on April 2004

Chlamydophila pneumoniae HflX belongs to an uncharacterized family of conserved GTPases and associates with the Escherichia coli 50S large ribosomal subunit.

scientific article

Comparative genomic analysis of human Chlamydia pneumoniae isolates from respiratory, brain and cardiac tissues

scientific article published on 26 September 2015

Comparative genomics of koala, cattle and sheep strains of Chlamydia pecorum

scientific article

Comparison of DNA-spot hybridization, cell culture and direct immunofluorescence staining for the diagnosis of avian chlamydiae

scientific article published on September 1988

Comparison of antigen detection and quantitative PCR in the detection of chlamydial infection in koalas (Phascolarctos cinereus).

scientific article published on September 2012

Comparison of koala LPCoLN and human strains of Chlamydia pneumoniae highlights extended genetic diversity in the species

scientific article

Comparison of subcutaneous versus intranasal immunization of male koalas (Phascolarctos cinereus) for induction of mucosal and systemic immunity against Chlamydia pecorum

scientific article published on 03 January 2015

Conserved DNA sequences in chlamydial plasmids

scientific article published on September 1989

Culture-independent genome sequencing of clinical samples reveals an unexpected heterogeneity of infections by Chlamydia pecorum.

scientific article

DNA fingerprint analysis of a free-range koala population

scholarly article by Peter Timms published in October 1993

DNA polymorphisms and subpopulations in Babesia bovis

scientific article published on April 1984

Detection of Chlamydia pneumoniae DNA and antigen in the circulating mononuclear cell fractions of humans and koalas

scientific article

Detection of Chlamydia trachomatis in urine using enzyme immunoassay and DNA amplification

scientific article published on December 1993

Development of a quantitative gene expression assay for Chlamydia trachomatis identified temporal expression of sigma factors

scientific article published on September 1999

Development of babesial vaccines

scientific article published on January 1989

Development status and future prospects for a vaccine against Chlamydia trachomatis infection

scientific article published on 22 August 2013

Differential expression of chlamydial signal transduction genes in normal and interferon gamma-induced persistent Chlamydophila pneumoniae infections

scientific article published on 22 July 2005

Differential expression of genes encoding membrane proteins between acute and continuous Chlamydia pneumoniae infections

scientific article published on January 2003

Differential expression of ompA, ompB, pyk, nlpD and Cpn0585 genes between normal and interferon-gamma treated cultures of Chlamydia pneumoniae

scientific article published on June 2001

Discordant detection of Chlamydia pneumoniae in patients with carotid artery disease using polymerase chain reaction, immunofluorescence microscopy and serological methods

scientific article published on February 2005

Distribution of Chlamydia pneumoniae DNA in atherosclerotic carotid arteries: significance for sampling procedures

scientific article published on April 2003

Divergent outcomes following transcytosis of IgG targeting intracellular and extracellular chlamydial antigens

scientific article

Effects of inoculating dose on the kinetics of Chlamydia muridarum genital infection in female mice.

scientific article published on 10 February 2009

Elucidating the host-pathogen interaction between human colorectal cells and invading Enterovirus 71 using transcriptomics profiling

scientific article

Endogenous and exogenous koala retrovirus patterns in wild koalas across Australia. In Proceedings of the Second Koala Retrovirus Workshop, ed. D. E. Alquezar-Planas, D. P. Higgins, C. L. Singleton, and A. D. Greenwood

scientific article published in 2023

Enterovirus71 (EV71) utilise host microRNAs to mediate host immune system enhancing survival during infection

scientific article

Epizootiology of Chlamydia infections in two free-range koala populations.

scientific article published on March 1999

Ethnic variation in inflammatory profile in tuberculosis

scientific article

Evaluation of intra- and extra-epithelial secretory IgA in chlamydial infections

scientific article published on December 2014

Evaluation of the relationship between Chlamydia pecorum sequence types and disease using a species-specific multi-locus sequence typing scheme (MLST).

scientific article published on 27 August 2014

Evidence of a conserved role for Chlamydia HtrA in the replication phase of the chlamydial developmental cycle

scientific article published on 25 July 2014

Evidence that human Chlamydia pneumoniae was zoonotically acquired

scientific article published on 11 September 2009

Evolution to a chronic disease niche correlates with increased sensitivity to tryptophan availability for the obligate intracellular bacterium Chlamydia pneumoniae

scientific article

Expression library immunization confers partial protection against Chlamydia muridarum genital infection.

scientific article

Failure to detect Chlamydia pneumoniae in atherosclerotic plaques of Australian patients.

scientific article published on May 1998

Genetic diversity and gene flow among southeastern Queensland koalas (Phascolarctos cinereus).

scientific article published on February 2000

Genetic diversity in the plasticity zone and the presence of the chlamydial plasmid differentiates Chlamydia pecorum strains from pigs, sheep, cattle, and koalas

scientific article published on 4 November 2015

Genetic diversity of Chlamydia pecorum strains in wild koala locations across Australia and the implications for a recombinant C. pecorum major outer membrane protein based vaccine.

scientific article published on 18 August 2013

Genetic variation in captive koalas (Phascolarctos cinereus): parentage determination and individual identification

scientific article published on 01 June 1998

Genome-wide analysis of chlamydiae for promoters that phylogenetically footprint

scientific article published on 18 October 2007

HtrA, RseP, and Tsp proteins do not elicit a pathology-related serum IgG response during sexually transmitted infection with Chlamydia trachomatis

scientific article published on 04 May 2010

Human Chlamydia pneumoniae isolates demonstrate ability to recover infectivity following penicillin treatment whereas animal isolates do not.

scientific article published on 05 February 2015

Human and Pathogen Factors Associated with Chlamydia trachomatis-Related Infertility in Women

scientific article

Identification and mapping of sigma-54 promoters in Chlamydia trachomatis

scientific article

Identification of Chlamydia pneumoniae proteins in the transition from reticulate to elementary body formation

scientific article published on 18 August 2006

Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis.

scientific article published on 12 July 2013

Identification of novel markers for uncomplicated lower genital tract infections and upper genital tract pathology due to Chlamydia trachomatis

scientific article published on 03 February 2011

Identification, characterisation and expression analysis of natural killer receptor genes in Chlamydia pecorum infected koalas (Phascolarctos cinereus)

scientific article published on 15 October 2015

Immune responses of cattle following vaccination with living and non-living Babesia bovis antigens

article

Immunity against a Chlamydia infection and disease may be determined by a balance of IL-17 signaling.

scientific article published on 24 December 2013

Immunization with a MOMP-based vaccine protects mice against a pulmonary Chlamydia challenge and identifies a disconnection between infection and pathology

scientific article

Immunopathogenesis of chlamydia trachomatis infections in women

scientific article

Improved prediction of bacterial transcription start sites

scientific article published on 15 November 2005

In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia, NrdB.

scientific article published on 18 January 2008

In vitro characterisation of koala Chlamydia pneumoniae: morphology, inclusion development and doubling time

scientific article published on 17 October 2008

Increased sensitivity to tryptophan bioavailability is a positive adaptation by the human strains of Chlamydia pneumoniae.

scientific article published on 22 July 2014

Interaction of microbiology and pathology in women undergoing investigations for infertility

scientific article published on September 2004

Interleukin 17A is an immune marker for chlamydial disease severity and pathogenesis in the koala (Phascolarctos cinereus)

scientific article (publication date: October 2014)

Investigation of the koala (Phascolarctos cinereus) hindgut microbiome via 16S pyrosequencing.

scientific article

Is Chlamydia to Blame for Koala Reproductive Cysts?

scientific article published on 4 September 2021

Isolation and antimicrobial susceptibilities of Chlamydial isolates from Western barred bandicoots

scientific article

Kinematics of intracellular chlamydiae provide evidence for contact-dependent development

scientific article

Koala biovar of Chlamydia pneumoniae infects human and koala monocytes and induces increased uptake of lipids in vitro

scientific article published on December 2001

Lack of antiviral antibody response in koalas infected with koala retroviruses (KoRV).

scientific article published on 14 January 2015

Longitudinal study of vitamin D metabolites after long bone fracture

scientific article

Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS).

scientific article

Modeling the impact of potential vaccines on epidemics of sexually transmitted Chlamydia trachomatis infection

scientific article published on June 2009

Modulation of the Chlamydia trachomatis in vitro transcriptome response by the sex hormones estradiol and progesterone.

scientific article

Molecular and pathological insights into Chlamydia pecorum-associated sporadic bovine encephalomyelitis (SBE) in Western Australia

scientific article

Molecular characterisation and expression analysis of interferon gamma in response to natural Chlamydia infection in the koala, Phascolarctos cinereus

scientific article published on 18 June 2013

Molecular characterization of Chlamydophila pneumoniae isolates from Western barred bandicoots

scientific article published on March 2007

Molecular evidence for novel chlamydial infections in the koala (Phascolarctos cinereus).

scientific article published on June 2003

Molecular vaccines against parasites

scientific article

Multilocus Sequence Analysis Provides Insights into Molecular Epidemiology of Chlamydia pecorum Infections in Australian Sheep, Cattle, and Koalas

scientific article published on 05 June 2013

Multiple genotypes of Chlamydia pneumoniae identified in human carotid plaque

scientific article published on July 2005

Navigating to the most promising directions amid complex fields of vaccine development: a chlamydial case study

scientific article published on 10 December 2019

Novel PCR-EIA method for the detection of Chlamydia pneumoniae in respiratory specimens

scientific article published on February 2002

Novel molecular markers of Chlamydia pecorum genetic diversity in the koala (Phascolarctos cinereus).

scientific article

Novel sequence types of Chlamydia pecorum infect free-ranging Alpine ibex (Capra ibex) and red deer (Cervus elaphus) in Switzerland

scientific article published on 03 February 2015

PCR detection and differentiation of Chlamydia pneumoniae, Chlamydia psittaci and Chlamydia trachomatis

scientific article published on October 1992

Partial protection against chlamydial reproductive tract infection by a recombinant major outer membrane protein/CpG/cholera toxin intranasal vaccine in the guinea pig Chlamydia caviae model

scientific article published on September 2011

Peptide immunization of guinea pigs against Chlamydia psittaci (GPIC agent) infection induces good vaginal secretion antibody response, in vitro neutralization and partial protection against live challenge

scientific article published on June 2001

Phylogenetic comparison of the known Chlamydia trachomatis sigma(66) promoters across to Chlamydia pneumoniae and Chlamydia caviae identifies seven poorly conserved promoters

scientific article published on 23 July 2008

Plasma tissue inhibitor of metalloproteinase-1 levels are elevated in essential hypertension and related to left ventricular hypertrophy

scientific article published on 01 March 2002

Poly-immunoglobulin receptor-mediated transport of IgA into the male genital tract is important for clearance of Chlamydia muridarum infection

scientific article

Preliminary characterisation of tumor necrosis factor alpha and interleukin-10 responses to Chlamydia pecorum infection in the koala (Phascolarctos cinereus)

scientific article

Progesterone activates multiple innate immune pathways in Chlamydia trachomatis-infected endocervical cells.

scientific article

Proof of concept: A bioinformatic and serological screening method for identifying new peptide antigens for Chlamydia trachomatis related sequelae in women

scientific article published on 13 May 2013

Protein A as a fusion partner for the expression of heterologous proteins in Lactobacillus.

scientific article

Protein expression profiles of Chlamydia pneumoniae in models of persistence versus those of heat shock stress response

scientific article published on July 2006

Randomly amplified polymorphic DNA variation in populations of eastern Australian koalas, Phascolarctos cinereus

scientific article published on 01 December 1998

Recent advances in understanding the biology, epidemiology and control of chlamydial infections in koalas

scientific article (publication date: August 2013)

Reduced levels of gamma-interferon secretion in response to chlamydial 60 kDa heat shock protein amongst women with pelvic inflammatory disease and a history of repeated Chlamydia trachomatis infections

scientific article published on May 2002

Reduction of fensulfothion and accumulation of the product, fensulfothion sulfide, by selected microbes

scientific article published on 01 July 1983

Retroviral integrations contribute to elevated host cancer rates during germline invasion

scientific article published on 26 February 2021

SNP marker discovery in koala TLR genes

scientific article

Solid-phase amplification and detection: a single-tube diagnostic assay for infectious agents.

scientific article published on June 2001

Spatial constraints within the chlamydial host cell inclusion predict interrupted development and persistence

scientific article

THE PARADOX OF EUTHANIZING KOALAS (PHASCOLARCTOS CINEREUS) TO SAVE POPULATIONS FROM ELIMINATION.

scientific article published on 17 August 2015

The Epidemiology of Chlamydia trachomatis Organism Load During Genital Infection: A Systematic Review

scientific article

The cross-species prediction of bacterial promoters using a support vector machine

scientific article published on 15 July 2008

The duration of Chlamydia muridarum genital tract infection and associated chronic pathological changes are reduced in IL-17 knockout mice but protection is not increased further by immunization.

scientific article

The effects of calcitriol treatment in glucocorticoid-resistant asthma

scientific article published on 29 April 2014

The effects of vitamin D₂ or D₃ supplementation on glycaemic control and related metabolic parameters in people at risk of type 2 diabetes: protocol of a randomised double-blind placebo-controlled trial

scientific article published on 23 October 2013

The koala immunological toolkit: sequence identification and comparison of key markers of the koala (Phascolarctos cinereus) immune response

article

The protease inhibitor JO146 demonstrates a critical role for CtHtrA for Chlamydia trachomatis reversion from penicillin persistence

scientific article published on 18 December 2013

The role of the multiple banded antigen of Ureaplasma parvum in intra-amniotic infection: major virulence factor or decoy?

scientific article

The temperature activated HtrA protease from pathogen Chlamydia trachomatis acts as both a chaperone and protease at 37 degrees C.

scientific article published on 26 June 2007

Therapeutic vaccination of koalas harbouring endogenous koala retrovirus (KoRV) improves antibody responses and reduces circulating viral load

scientific article published on 16 July 2020

Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infection

scientific article

Treatment efficacy of azithromycin 1 g single dose versus doxycycline 100 mg twice daily for 7 days for the treatment of rectal chlamydia among men who have sex with men - a double-blind randomised controlled trial protocol

scientific article

Treatment of rectal chlamydia infection may be more complicated than we originally thought.

scientific article published on 04 December 2014

Twenty years of research into Chlamydia-like organisms: a revolution in our understanding of the biology and pathogenicity of members of the phylum Chlamydiae.

scientific article published on 04 December 2014

Type III secretion à la Chlamydia

scientific article published on 7 May 2007

Type III secretion, contact-dependent model for the intracellular development of chlamydia

scientific article published on January 2006

Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model

scientific article published on October 2001

Unexpected Pathogen Diversity Detected in Australian Avifauna Highlights Potential Biosecurity Challenges

scientific article published on 2 January 2023

Unique residues involved in activation of the multitasking protease/chaperone HtrA from Chlamydia trachomatis.

scientific article

Ureaplasma parvum and Ureaplasma urealyticum are detected in semen after washing before assisted reproductive technology procedures

article

Use of a commercial assay for detecting the 60 kDa chlamydial heat shock protein in a range of patient groups

scientific article published on February 2006

Use of quantitative real-time PCR to monitor the shedding and treatment of chlamydiae in the koala (Phascolarctos cinereus).

scientific article

Using quantitative polymerase chain reaction to correlate Chlamydia pecorum infectious load with ocular, urinary and reproductive tract disease in the koala (Phascolarctos cinereus).

scientific article published on October 2011

Vaccination of healthy and diseased koalas (Phascolarctos cinereus) with a Chlamydia pecorum multi-subunit vaccine: evaluation of immunity and pathology

scientific article published on 09 January 2012

Vaccination of koalas (Phascolarctos cinereus) with a recombinant chlamydial major outer membrane protein adjuvanted with poly I:C, a host defense peptide and polyphosphazine, elicits strong and long lasting cellular and humoral immune responses.

scientific article published on 04 September 2014

Vaccination of koalas with a prototype chlamydial vaccine is safe, does not increase the incidence of lymphoma-related disease and maybe associated with increased lifespan in captive koalas

scientific article published on 21 July 2015

Vaccination of koalas with a recombinant Chlamydia pecorum major outer membrane protein induces antibodies of different specificity compared to those following a natural live infection

scientific article

Vaccination to protect against infection of the female reproductive tract.

scientific article published on January 2012

Variation in koala microbiomes within and between individuals: effect of body region and captivity status.

scientific article published on 11 May 2015

Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial

scientific article

Wide range of Chlamydiales types detected in native Australian mammals

scientific article published on October 2003

cDNA clone encoding a high molecular weight antigen of Babesia bovis

scientific article

the active site residue V266 of Chlamydial HtrA is critical for substrate binding during both in vitro and in vivo conditions

scientific article published on 21 February 2012