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List of works by Jonathan Mill

5-hydroxymethylcytosine is highly dynamic across human fetal brain development

scientific article published on 18 September 2017

A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy.

scientific article published in January 2006

A comparison of mitochondrial DNA isolation methods in frozen post-mortem human brain tissue--applications for studies of mitochondrial genetics in brain disorders

scientific article

A cross-brain regions study of ANK1 DNA methylation in different neurodegenerative diseases

A data-driven approach to preprocessing Illumina 450K methylation array data

scientific article

A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex

scientific article published on 22 October 2018

A longitudinal study of epigenetic variation in twins

scientific article

A longitudinal twin study of skewed X chromosome-inactivation

scientific article

A multi-tissue analysis identifies HLA complex group 9 gene methylation differences in bipolar disorder

scientific article published on 7 June 2011

ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.

scientific article

Advanced paternal age effects in neurodevelopmental disorders-review of potential underlying mechanisms

scientific article published on 31 January 2017

Advanced paternal age is associated with altered DNA methylation at brain-expressed imprinted loci in inbred mice: implications for neuropsychiatric disease.

scientific article published on 26 June 2012

Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model

scientific article

Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model

scientific article published on 6 February 2016

Allele-specific methylation in the human genome: implications for genetic studies of complex disease

scientific article

Allelic skewing of DNA methylation is widespread across the genome

scientific article

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

scientific article published on 27 November 2019

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

scientific article

An epigenome-wide association meta-analysis of prenatal maternal stress in neonates: A model approach for replication

scientific article published on 18 February 2016

Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood

scientific article published on 12 January 2018

Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients

scientific article

Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer's Disease patients.

scientific article published on 23 June 2012

Anxiety sensitivity in adolescence and young adulthood: the role of stressful life events, 5HTTLPR and their interaction.

scientific article published on 23 March 2012

Application of microarrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes

article

Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology

scientific article published on 19 March 2021

Association of DRD4 in children with ADHD and comorbid conduct problems

scientific article published in March 2002

Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis

scientific article published on 18 May 2015

Association study of a SNAP-25 microsatellite and attention deficit hyperactivity disorder

scientific article (publication date: 8 April 2002)

Association study of a dopamine transporter polymorphism and attention deficit hyperactivity disorder in UK and Turkish samples

scientific article published in July 2001

Association study of promoter polymorphisms at the dopamine transporter gene in Attention Deficit Hyperactivity Disorder

scientific article

Association study of the estrogen receptor alpha gene (ESR1) and childhood-onset mood disorders.

scientific article published in October 2008

Attention deficit hyperactivity disorder (ADHD) and the dopamine D4 receptor gene: evidence of association but no linkage in a UK sample

scientific article published in July 2001

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

scientific article published in Nature Communications

Bigmelon: tools for analysing large DNA methylation datasets

scientific article published on 01 March 2019

Bisphenol A causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio)

scientific article

Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation

scientific article published on 10 March 2009

Blood methylomic signatures of presymptomatic dementia in elderly subjects with type 2 diabetes mellitus

scientific article published on 24 December 2014

Brain weight in males is correlated with DNA methylation at IGF2.

scientific article published on 15 December 2009

Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins

scientific article published on 09 August 2018

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

scientific article published on 24 August 2016

Commentary: The seven plagues of epigenetic epidemiology ⬇️

scientific article published on January 23, 2012

Cross-reactive probes on Illumina DNA methylation arrays: a large study on ALS shows that a cautionary approach is warranted in interpreting epigenome-wide association studies

scientific article published on 17 December 2020

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.

scientific article

Current status and future prospects for epigenetic psychopharmacology

scientific article

DNA Methylation Profiling in Inflammatory Bowel Disease Provides New Insights into Disease Pathogenesis

scientific article published on 28 September 2015

DNA from buccal swabs recruited by mail: evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping

scientific article published on 01 January 2003

DNA methylation and substance-use risk: a prospective, genome-wide study spanning gestation to adolescence.

scientific article published on 06 December 2016

DNA methylation profiling using bisulfite-based epityping of pooled genomic DNA.

scientific article

DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample

scientific article published on 29 December 2020

DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

scientific article

DNA modification study of major depressive disorder: beyond locus-by-locus comparisons

scientific article

DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association

scientific article

Decreased methylation of the NK3 receptor coding gene (TACR3) after cocaine-induced place preference in marmoset monkeys

scientific article published on 9 November 2011

Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth

scientific article published in January 2008

Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction

article

Differential methylation of the TRPA1 promoter in pain sensitivity

scientific article published on January 2014

Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder

scientific article

Drugs and addiction: an introduction to epigenetics.

scientific article

DunedinPACE, a DNA methylation biomarker of the pace of aging

DunedinPACE: A DNA methylation biomarker of the Pace of Aging

Eating disorders, gene-environment interactions and epigenetics

scientific article

Effects of advanced paternal age on trajectories of social behavior in offspring.

scientific article published on July 2015

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

article

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

scientific article published on 28 March 2018

Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study.

scientific article

Epigenetic Research in Neuropsychiatric Disorders: the "Tissue Issue".

scientific article published on 2 August 2016

Epigenetic and genetic variation at the IGF2/H19 imprinting control region on 11p15.5 is associated with cerebellum weight

scientific article (publication date: February 2012)

Epigenetic mediation of environmental influences in major psychotic disorders

scientific article

Epigenetic profiling of ADHD symptoms trajectories: a prospective, methylome-wide study

scientific article published on 24 May 2016

Epigenetic regulation of mitochondrial function in neurodegenerative disease: New insights from advances in genomic technologies

scientific article published on 10 February 2016

Epigenetic signatures of childhood abuse and neglect: Implications for psychiatric vulnerability

scientific article published on 13 September 2016

Epigenetic studies of psychosis: current findings, methodological approaches, and implications for postmortem research

scientific article

Epigenetic studies of schizophrenia: progress, predicaments, and promises for the future

scientific article

Epigenetically regulated microRNAs in Alzheimer's disease.

scientific article published on 18 October 2013

Epigenetics in health and disease: heralding the EWAS era

scientific article published in The Lancet

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

scientific article published on 01 March 2019

Epigenome-wide association study of attention-deficit/hyperactivity disorder in adults

scientific article published on 19 June 2020

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population

scientific article

Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain

scientific article

Epigenomic profiling reveals DNA-methylation changes associated with major psychosis

scientific article

Erasure and reestablishment of random allelic expression imbalance after epigenetic reprogramming

scientific article published on 18 August 2016

Erratum to: Variation in 5-hydroxymethylcytosine across human cortex and cerebellum

scientific article published on 17 June 2016

Erratum: Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain

scholarly article published in Translational Psychiatry

Establishing a generalized polyepigenetic biomarker for tobacco smoking

scientific article published on 15 February 2019

Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene

scientific article

Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study

scientific article

Expression of the dopamine transporter gene is regulated by the 3' UTR VNTR: Evidence from brain and lymphocytes using quantitative RT-PCR.

scientific article published in December 2002

Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

Family-based association study between brain-derived neurotrophic factor gene polymorphisms and attention deficit hyperactivity disorder in UK and Taiwanese samples

scientific article published in January 2007

Family-based association study of serotonin transporter gene polymorphisms in attention deficit hyperactivity disorder: no evidence for association in UK and Taiwanese samples

scientific article published in November 2005

From promises to practical strategies in epigenetic epidemiology ⬇️

scientific article published on July 2, 2013

Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing

scientific article published on 01 November 2021

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

scientific article

Functional effects of a tandem duplication polymorphism in the 5'flanking region of the DRD4 gene

scientific article

Genetic architecture of epigenetic and neuronal ageing rates in human brain regions

scientific article

Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains

scientific article published on 28 January 2019

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum

scientific article

Genetic variation at 16q24.2 is associated with small vessel stroke

scientific article

Genetics and the geography of health, behaviour and attainment.

scientific article published on 8 April 2019

Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans

scientific article published on 21 March 2016

Genome-wide DNA methylation meta-analysis in the brains of suicide completers

scientific article published on 19 February 2020

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue

scientific article published on 01 July 2019

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide methylomic analysis in individuals with HNF1B intragenic mutation and 17q12 microdeletion

scientific article published on 18 July 2018

Genome-wide methylomic analysis of monozygotic twins discordant for adolescent depression

scientific article

Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging

scientific article published on 03 June 2019

Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

scientific article published on 14 May 2019

Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD.

scientific article published in August 2004

Histone Acetylome-wide Association Study of Autism Spectrum Disorder.

scientific article

Home-cage activity in heterogeneous stock (HS) mice as a model of baseline activity

scientific article published in August 2002

Hypermethylation in the ZBTB20 gene is associated with major depressive disorder

scientific article

Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain

scientific article

Independent Methylome-Wide Association Studies of Schizophrenia Detect Consistent Case-Control Differences

scientific article published on 01 February 2020

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

scientific article (publication date: 18 July 2003)

Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus

scientific article

Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism

scientific article published on 25 September 2020

Is treatment-resistant schizophrenia categorically distinct from treatment-responsive schizophrenia? a systematic review.

scientific article

Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes

scientific article

Large epigenome-wide association study of childhood ADHD identifies peripheral DNA methylation associated with disease and polygenic risk burden

scientific article published on 21 January 2020

Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits

article

Leveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits

article

Long-lasting regulation of hippocampal Bdnf gene transcription after contextual fear conditioning.

scientific article published on 30 May 2012

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

scientific article

Longitudinal investigation of DNA methylation changes preceding adolescent psychotic experiences

scientific article published on 04 February 2019

Mapping epigenetic changes to the host cell genome induced by Burkholderia pseudomallei reveals pathogen-specific and pathogen-generic signatures of infection

scientific article published on 3 August 2016

Meta-analysis of epigenome-wide association studies of cognitive abilities

scientific article published on 8 January 2018

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

scientific article published on 26 March 2021

Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

scientific article

Methylation age acceleration does not predict mortality in schizophrenia

scientific article published on 04 June 2019

Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits

scientific article published on 23 April 2013

Methylomic analysis of salivary DNA in childhood ADHD identifies altered DNA methylation in VIPR2.

scientific article

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

scientific article

Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide

scientific article published on 3 January 2017

Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

scientific article

Molecular studies of major depressive disorder: the epigenetic perspective

scientific article published on 10 April 2007

Mutation screen and association analysis of the glucocorticoid receptor gene (NR3C1) in childhood-onset mood disorders (COMD).

scientific article published in September 2009

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

scientific article published on 24 July 2020

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

scientific article published on 21 March 2019

Paternal Age Alters Social Development in Offspring

scientific article

Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study

scientific article published on 25 April 2018

Pleiotropic Effects of Trait-Associated Genetic Variation on DNA Methylation: Utility for Refining GWAS Loci.

scientific article

Polymorphisms in the dopamine D4 receptor gene and attention-deficit hyperactivity disorder

scientific article published in August 2003

Polymorphisms in the dopamine D5 receptor (DRD5) gene and ADHD.

scientific article published in February 2004

Pre- and peri-natal environmental risks for attention-deficit hyperactivity disorder (ADHD): the potential role of epigenetic processes in mediating susceptibility

scientific article

Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts

scientific article

Prenatal immune activation alters the adult neural epigenome but can be partly stabilised by a n-3 polyunsaturated fatty acid diet.

scientific article

Profiling DNA methylation from small amounts of genomic DNA starting material: efficient sodium bisulfite conversion and subsequent whole-genome amplification

scientific article published in January 2009

Profiling Regulatory Variation in the Brain: Methods for Exploring the Neuronal Epigenome.

scientific article published in January 2017

QTL association analysis of the DRD4 exon 3 VNTR polymorphism in a population sample of children screened with a parent rating scale for ADHD symptoms.

scientific article published in May 2001

Quantitative promoter DNA methylation analysis of four candidate genes in anorexia nervosa: a pilot study

scientific article published on 22 November 2012

Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP-25, and 5HT1B.

scientific article published in February 2005

Rapid Down-Regulation of Glucocorticoid Receptor Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and MicroRNA Activity.

scientific article published on 8 April 2016

Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

scientific article

Research Highlights: Epigenetic changes to serotonin receptor gene expression in schizophrenia and bipolar disorder ⬇️

scientific article published on 01 October 2011

Rodent models: utility for candidate gene studies in human attention-deficit hyperactivity disorder (ADHD).

scientific article published on 17 January 2007

Role of genotype in the cycle of violence in maltreated children

scientific article (publication date: 2 August 2002)

SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer's Disease.

scientific article

Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition

scientific article

Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions

scientific article published on 22 December 2016

Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1.

scientific article published on 07 June 2016

Sex-specific transcription and DNA methylation profiles of reproductive and epigenetic associated genes in the gonads and livers of breeding zebrafish.

scientific article published on 12 April 2018

Sleep quality and diurnal preference in a sample of young adults: associations with 5HTTLPR, PER3, and CLOCK 3111.

scientific article

Socioeconomic Position and DNA Methylation Age Acceleration Across the Life Course

scientific article published on 01 November 2018

Stochastic choice of allelic expression in human neural stem cells

scientific article

Stress-induced gene expression and behavior are controlled by DNA methylation and methyl donor availability in the dentate gyrus

scientific article published on 12 April 2016

The dopamine transporter gene is associated with attention deficit hyperactivity disorder in a Taiwanese sample.

scientific article published in April 2003

The mitochondrial epigenome: a role in Alzheimer's disease?

scientific article published on January 2014

The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression

scientific article

Tissue-specific patterns of allelically-skewed DNA methylation

scientific article published on 19 January 2016

Toward an integrated genetic and epigenetic approach to Alzheimer's disease

scientific article published on 16 April 2011

Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies

scientific article published on 26 February 2010

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

scientific article (publication date: 25 May 2011)

Transcriptomic changes in the frontal cortex associated with paternal age.

scientific article published on 23 March 2014

Transient expression analysis of allelic variants of a VNTR in the dopamine transporter gene (DAT1)

scientific article

Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.

scientific article published on 16 February 2016

Whole genome amplification of sodium bisulfite-treated DNA allows the accurate estimate of methylated cytosine density in limited DNA resources.

scientific article published in November 2006

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