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List of works by Stephen Fox

"Cancer 2015": A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic

scientific article

"Overcoming breast cancer drug resistance with mTOR inhibitors". Could it be a myth or a real possibility in the short-term future?

scientific article published on 14 October 2010

A MXI1-NUTM1 fusion protein with MYC-like activity suggests a novel oncogenic mechanism in a subset of NUTM1-rearranged tumors

scientific article published on 01 September 2020

A Prospective Pathologic Study to Define the Clinical Target Volume for Partial Breast Radiation Therapy in Women With Early Breast Cancer

scientific article published on 28 April 2012

A fully human inhibitory monoclonal antibody to the Wnt receptor RYK

scientific article

A high-throughput protocol for mutation scanning of the BRCA1 and BRCA2 genes

scientific article

A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting

scientific article published on 08 October 2009

A multiplex endpoint RT-PCR assay for quality assessment of RNA extracted from formalin-fixed paraffin-embedded tissues

scientific article

A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma

scientific article published on January 2013

A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma

scientific article

A randomized controlled trial investigating the effects of celecoxib in patients with localized prostate cancer.

scientific article published in May 2009

ALK-Rearranged Non-Small Cell Lung Cancer in 2020: Real-World Triumphs in an Era of Multigeneration ALK-Inhibitor Sequencing Informed by Drug Resistance Profiling

scientific article published on 18 June 2020

ASCO/CAP 2018 breast cancer HER2 testing guidelines: summary of pertinent recommendations for practice in Australia

scientific article published on 07 May 2019

Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer

scientific article published on 14 July 2011

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

scientific article published on 2 August 2009

Absence of retroviral vector-mediated transformation of gene-modified T cells after long-term engraftment in mice

scientific article published on 27 March 2008

Abstract 2962: LRH-1 expression in breast cancer tissue and its association with phenotype and DNA methylation

article published in 2015

Abstract 38: Using molecularly characterized patient-derived models to delineate underlying drivers and vulnerabilities of epithelial ovarian cancer

Abstract A72: The E3-ligase E6AP represses breast cancer metastasis through regulation of ECT2-Rho-GTPases signaling

Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study

scientific article published on 04 September 2012

Adequate tumour cellularity is essential for accurate PD-L1 immunohistochemistry assessment on cytology cell-block specimens

scientific article published on 11 January 2020

Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothelial cells and induce its desensitisation by different mechanisms.

scientific article published on March 2006

Adrenomedullin and tumour angiogenesis.

scientific article

Altered significance of D'Amico risk classification in patients with prostate cancer linked to a familial breast cancer (kConFab) cohort

scientific article published on 6 April 2015

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

scientific article published on 04 December 2018

An Immunohistochemical and Prognostic Evaluation of Cathepsin D Expression in 105 Bladder Carcinomas

article published in 1995

An immunohistochemical and prognostic evaluation of cathepsin D expression in 105 bladder carcinomas

scientific article published on 01 July 1995

Angiogenesis as a biologic and prognostic indicator in human breast carcinoma.

scientific article published on January 1997

Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs

scientific article

Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival

scientific article

Angiopoietin-1 is inversely related to thymidine phosphorylase expression in human breast cancer, indicating a role in vascular remodeling.

scientific article published on April 2001

Anti-angiogenic effect of tamoxifen combined with epirubicin in breast cancer patients

scientific article published on 3 August 2010

Antitumor activities and on-target toxicities mediated by a TRAIL receptor agonist following cotreatment with panobinostat

article

Apatinib for the treatment of gastric cancer

scientific article published on 15 July 2016

Applicability of next generation sequencing technology in microsatellite instability testing

scientific article

Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast

scientific article

Assessing HER2 amplification in breast cancer: findings from the Australian In Situ Hybridization Program

scientific article

Assessing Tumor Angiogenesis in Histological Samples

scientific article published in January 2016

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Ca

scientific article published on 2 August 2017

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in I

scientific article published in September 2017

Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

scientific article

Assessing tumor angiogenesis in histological samples

scientific article published in January 2009

Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour

scientific article published on 9 October 2015

Association between platelet microthrombi and finger clubbing

scientific article published in The Lancet

Association of Tumor Angiogenesis With Bone Marrow Micrometastases in Breast Cancer Patients

scientific article published on 01 July 1997

Association of tumour necrosis factor alpha and its receptors with thymidine phosphorylase expression in invasive breast carcinoma

scientific article

Atypical ductal hyperplasia is a multipotent precursor of breast carcinoma

scientific article published on 22 April 2019

Australian consensus statement for best practice ROS1 testing in advanced non-small cell lung cancer

scientific article published on 24 October 2019

Australian recommendations for EGFR T790M testing in advanced non-small cell lung cancer

scientific article

BNIP3 as a Progression Marker in Primary Human Breast Cancer; Opposing Functions inIn situVersus Invasive Cancer

BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group

scientific article

BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression

scientific article published on September 2009

BRCA2 carriers with male breast cancer show elevated tumour methylation

scientific article published on 11 September 2017

Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

scientific article

Bcl-2 and p53 expression in node-negative breast carcinoma: A study with long-term follow-up

scientific article published on 01 November 1996

Biobanking in Cancer Research

scientific article published in 2016

Blood vessel invasion and other variables as predictors of long-term survival in Japanese and British patients with primary invasive breast cancer.

scientific article

Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing

scientific article published on 16 November 2016

Breast Tissue Composition and Immunophenotype and Its Relationship with Mammographic Density in Women at High Risk of Breast Cancer

scientific article published on 25 June 2015

Breast cancer angiogenesis--new approaches to therapy via antiangiogenesis, hypoxic activated drugs, and vascular targeting

scientific article published on January 1996

Breast cancer angiogenesis: Therapy target and prognostic factor

scientific article published on 01 January 1995

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

scientific article published on 13 August 2003

Breast cancer prognostic classification in the molecular era: the role of histological grade

scientific article

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer

scientific article published on 24 March 2017

Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management

scientific article

Breast tumour angiogenesis

scientific article published in January 2007

CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells

scientific article published on 01 February 2019

CD44 and cancer screening

scientific article published in The Lancet

CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

scientific article published on 17 July 2020

CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha

scientific article published in September 2004

CNspector: a web-based tool for visualisation and clinical diagnosis of copy number variation from next generation sequencing

scientific article published on 23 April 2019

COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment

scientific article

CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence

scientific article published on 08 October 2020

Canary: an atomic pipeline for clinical amplicon assays

scientific article published on 15 December 2017

Cancer 2015: a longitudinal whole-of-system study of genomic cancer medicine.

scientific article published on 19 October 2015

Case report: Extra-hepatic biliary cystadenoma in association with adenomyomatosis of the gall-bladder

scientific article published on 01 March 1991

Cisplatin Increases Sensitivity to FGFR Inhibition in Patient-Derived Xenograft Models of Lung Squamous Cell Carcinoma.

scientific article published on 13 June 2017

Clinical cancer genomic analysis: data engineering required

scientific article

Clinical implications of prospective genomic profiling of metastatic breast cancer patients

scientific article published on 18 August 2020

Cohesin Rad21 Mediates Loss of Heterozygosity and Is Upregulated via Wnt Promoting Transcriptional Dysregulation in Gastrointestinal Tumors

scientific article published in December 2014

Combination of letrozole, metronomic cyclophosphamide and sorafenib is well-tolerated and shows activity in patients with primary breast cancer

scientific article published on 2 December 2014

Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer

scientific article

Combined tumor sequencing and case/control analyses of RAD51C in breast cancer

scientific article published on 01 December 2019

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article published on 2 November 2011

Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers

scientific article published on 8 July 2015

Comparison of Four PD-L1 Immunohistochemical Assays in Lung Cancer

scientific article published on 23 November 2017

Comparison of methods in the detection of ALK and ROS1 rearrangements in lung cancer

scientific article

Constitutional methylation of the BRCA1 promoter is specifically associated with BRCA1 mutation-associated pathology in early-onset breast cancer

scientific article

Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry

scientific article

Controversies in the management of gastrointestinal stromal tumors

scientific article published on 27 March 2014

Copy number analysis by low coverage whole genome sequencing using ultra low-input DNA from formalin-fixed paraffin embedded tumor tissue.

scientific article

Copy number analysis of ductal carcinoma in situ with and without recurrence

scientific article

Correction: The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".

scientific article published on 21 April 2017

Correlation of Ataxia-Telangiectasia-Mutated (ATM) gene loss with outcome in head and neck squamous cell carcinoma

article

Cost-effectiveness of precision medicine in the fourth-line treatment of metastatic lung adenocarcinoma: An early decision analytic model of multiplex targeted sequencing

scientific article published on 2 June 2016

Cousins not twins: intratumoural and intertumoural heterogeneity in syndromic neuroendocrine tumours.

scientific article published on 31 March 2017

Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers

article

Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer

scientific article

DNA methylation analysis of the HIF-1α prolyl hydroxylase domain genes PHD1, PHD2, PHD3 and the factor inhibiting HIF gene FIH in invasive breast carcinomas

scientific article published on 19 August 2010

DNA methylation in ductal carcinoma in situ of the breast

scientific article published on 28 June 2013

DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast

Decreased Prostate Cancer-Specific Survival of Men withBRCA2 Mutations from Multiple Breast Cancer Families

scientific article published on 01 July 2011

Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting

scientific article

Determinants of variability of five programmed death ligand-1 immunohistochemistry assays in non-small cell lung cancer samples

scientific article published on 2 January 2018

Determination of angiogenesis adds information to estrogen receptor status in predicting the efficacy of adjuvant tamoxifen in node-positive breast cancer patients

scientific article published on 01 July 1996

Determining HER2 (ERBB2) amplification status in women with breast cancer: final results from the Australian in situ hybridisation program

scientific article published on 23 August 2016

Diagnostic issues with significant tumour displacement in breast biopsies

scientific article published on 11 September 2014

Differential expression of immunohistochemical markers in primary lung and breast cancers enriched for triple-negative tumours

scientific article published on 7 August 2015

Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome

scientific article

Distinct angiogenic patterns are associated with high-grade in situ ductal carcinomas of the breast

scientific article published in February 1997

Distinct molecular signature of inflammatory breast cancer by cDNA microarray analysis

scientific article published in October 2005

Does cyclin D1 discriminate betweenBRCA2andBRCAXbreast cancers?

scientific article published on 23 September 2009

Down-regulation of phosphatidylinositol 3'-kinase/AKT/molecular target of rapamycin metabolic pathway by primary letrozole-based therapy in human breast cancer

scientific article published on May 2008

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer

scientific article published on 03 April 2020

Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis

scientific article

Ductal carcinoma in situ - update on risk assessment and management

scientific article

E6AP Promotes a Metastatic Phenotype in Prostate Cancer

scientific article published on 02 November 2019

E6AP promotes prostate cancer by reducing p27 expression

scientific article published on 19 April 2017

E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis

scientific article published on 11 June 2012

EGFR mutations in exons 18-21 in sporadic breast cancer

scientific article published on 01 January 2007

Effect of Primary Letrozole Treatment on Tumor Expression of mTOR and HIF-1α and Relation to Clinical Response

scientific article

Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers ⬇️

scientific article

Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2 and BRCAX, but not BRCA1 familial breast cancers

scientific article

Establishment of the Australian in situ hybridization program for the assessment of HER2 amplification in breast cancer: a model for the introduction of new biomarkers into clinical practice.

scientific article

Exploring the feasibility and utility of exome-scale tumour sequencing in a clinical setting

scientific article published on 01 July 2018

Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines

scientific article published on February 2008

Expression of E6AP and PML predicts for prostate cancer progression and cancer-specific death

scientific article published on 17 September 2014

Expression of cathepsin D and estrogen receptor in male breast carcinoma

scientific article published on 01 February 1993

Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer

scientific article published on 20 October 2009

Expression of platelet-derived endothelial cell growth factor and vascularity in the nasal mucosa from allergic rhinitis

scientific article published on 01 November 2000

Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers

scientific article published on 01 October 1996

Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human p

scientific article published in March 1997

Expression of the angiopoietins and their receptor Tie2 in human renal clear cell carcinomas; regulation by the von Hippel-Lindau gene and hypoxia

scientific article published in December 2002

Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade

scientific article published in December 2003

Expression of the forkhead box transcription factor FOXP1 is associated with oestrogen receptor alpha, oestrogen receptor beta and improved survival in familial breast cancers

scientific article published on 20 July 2009

Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia

scientific article published on July 2007

Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas

scientific article

Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptor-beta in primary invasive breast carcinomas

scientific article published on 17 November 2007

Expression of vascular endothelial growth factor D is associated with hypoxia inducible factor (HIF-1alpha) and the HIF-1alpha target gene DEC1, but not lymph node metastasis in primary human breast carcinomas

scientific article published in August 2004

Fatal rupture of a subcapsular liver haematoma in a patient treated with anisolylated plasminogen streptokinase activated complex

scientific article published in July 1991

Findings from precision oncology in the clinic: rare, novel variants are a significant contributor to scaling molecular diagnostics

scientific article published on 28 March 2022

First international consensus on the methodology of lymphangiogenesis quantification in solid human tumours

scientific article published on 21 November 2006

Frequency of fibroblast growth factor receptor 1 gene amplification in oral tongue squamous cell carcinomas and associations with clinical features and patient outcome

scientific article published on 19 February 2013

Frequent activating STAT3 mutations and novel recurrent genomic abnormalities detected in breast implant-associated anaplastic large cell lymphoma

article

GATA3 expression in triple-negative breast cancers.

scientific article published on 17 February 2017

Gastric HER2 Testing Study (GaTHER): an evaluation of gastric/gastroesophageal junction cancer testing accuracy in Australia

scientific article published in April 2012

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

scientific article published on 19 September 2011

Gene therapy through signal transduction pathways and angiogenic growth factors as therapeutic targets in breast cancer.

scientific article published on August 1994

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

scientific article published on 3 October 2017

Genotypic and phenotypic analysis of familial male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated carcinomas

scientific article

HER2 status in gastric/gastro-oesophageal junctional cancers: should determination of gene amplification by SISH use HER2 copy number or HER2: CEP17 ratio?

scientific article published in April 2014

HER2 testing in advanced gastric and gastro-oesophageal cancer: analysis of an Australia-wide testing program

scientific article

HER2-positive breast cancer metastatic to intracranial meningioma: a case report

scientific article published on 22 February 2013

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

scientific article

HIF-1α stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma.

scientific article published on 8 April 2013

Heterogeneity of vascularisation in invasive breast carcinoma

scientific article published on 01 September 2002

High grade prostatic intraepithelial neoplasia does not display loss of heterozygosity at the mutation locus in BRCA2 mutation carriers with aggressive prostate cancer

scientific article

High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies

scientific article

High resolution melting for mutation scanning of TP53 exons 5-8

scientific article

Histological quantitation of tumour angiogenesis

scientific article

Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis

scientific article

Hypoxia-Inducible Factor-1 Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer

article

Hypoxia-related biological markers as predictors of epirubicin-based treatment responsiveness and resistance in locally advanced breast cancer

scientific article published on 14 August 2017

Immune molecular profiling of a multiresistant primary prostate cancer with a neuroendocrine-like phenotype: a case report

scientific article published on 28 October 2020

Immune system and angiogenesis-related potential surrogate biomarkers of response to everolimus-based treatment in hormone receptor-positive breast cancer: an exploratory study

scientific article published on 07 August 2020

Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer.

scientific article published on 29 June 2016

Immunomodulation of FOXP3+ regulatory T cells by the aromatase inhibitor letrozole in breast cancer patients

scientific article published in February 2009

Improved next-generation sequencing pre-capture library yields and sequencing parameters using on-bead PCR

scientific article published on 11 December 2019

In Response

scientific article published in August 2015

Incorporating progesterone receptor expression into the PREDICT breast prognostic model

scientific article published in 2022

Increased angiogenesis and lymphangiogenesis in inflammatory versus noninflammatory breast cancer by real-time reverse transcriptase-PCR gene expression quantification.

scientific article published in December 2004

Increased expression of CD44v6 and CD44v3 in ulcerative colitis but not colonic Crohn's disease

scientific article published in The Lancet

Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients.

scientific article published on 28 March 2007

Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal oestrogen and/or progesterone receptor-positive breast cancer

scientific article published on 11 April 2013

Increased regulatory T-cell numbers distinguish high-risk breast cancer patients and those at risk of late relapse.

scientific article published in November 2006

Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression

scientific article

Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

scientific article published on 03 February 2009

International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fifth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2013).

scientific article published on May 2015

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

scientific article published on January 2011

Interobserver variability in upfront dichotomous histopathological assessment of ductal carcinoma in situ of the breast: the DCISion study

scientific article published on 18 September 2019

Intra- and Interobserver Reproducibility Assessment of PD-L1 Biomarker in Non-Small Cell Lung Cancer

scientific article published on 18 April 2017

Invasion in breast lesions: the role of the epithelial-stroma barrier

scientific article published on 2 December 2017

Is it time for everolimus-based combination in castration-resistant prostate cancer?

scientific article published on 2 June 2016

KRAS mutation testing of metastatic colorectal cancer in Australia: where are we at?

scientific article published on 09 May 2014

LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness

scientific article published on 28 July 2017

Lack of c-erbB-2 oncoprotein expression in male breast carcinoma

scientific article

Lack of innervation of human umbilical cord. An immunohistological and histochemical study

scientific article published in January 1990

Langerhans cells in human lung tumours: an immunohistological study

scientific article published on 01 March 1989

Large genomic rearrangements in the familial breast and ovarian cancer gene BRCA1 are associated with an increased frequency of high risk features

scientific article published on June 2015

Lessons learnt from implementation of a Lynch syndrome screening program for patients with gynaecological malignancy.

scientific article published on 29 June 2017

Leukocyte adhesion-GPCR EMR2 is aberrantly expressed in human breast carcinomas and is associated with patient survival

scientific article

Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry

scientific article published on July 2013

Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines

scientific article

Loss of PML cooperates with mutant p53 to drive more aggressive cancers in a gender-dependent manner

scientific article published on 08 May 2013

Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.

scientific article

Low-grade fibromatosis-like spindle cell carcinomas of the breast are molecularly exiguous

scientific article published on 23 February 2015

Lymphangiogenesis and lymphatic vessel remodelling in cancer

scientific article published on March 2014

MDM4 is a rational target for treating breast cancers with mutant p53.

scientific article published on 18 January 2017

MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib

scientific article published on 31 October 2011

Mammographically dense human breast tissue stimulates MCF10DCIS.com progression to invasive lesions and metastasis

scientific article published on 25 October 2016

Markers of tumor angiogenesis: clinical applications in prognosis and anti-angiogenic therapy

scientific article published on January 1997

Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary

scientific article published on December 2013

Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines

scientific article published in July 1990

Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1

scientific article published on 17 September 2020

Metaplastic carcinomas of the breast without evidence of epithelial differentiation: A diagnostic approach for management

scientific article published on 28 October 2020

Metastatic gastrointestinal stromal tumour of the ileum with dual primary c-KIT missence mutations

scientific article published in October 2013

Methylation profiling of ductal carcinoma in situ and its relationship to histopathological features

scientific article

Microscopic Assessment of Angiogenesis in Tumors

scientific article published on 01 January 2001

Minichromosome maintenance protein 2 expression in normal kidney and renal cell carcinomas: relationship to tumor dormancy and potential clinical utility.

scientific article published on April 2002

Molecular Oncology and the Neoadjuvant Setting: the Perfect Blend for Treatment Personalization and Clinical Trial Design

scientific article published on 01 January 2011

Molecular comparison of interval and screen-detected breast cancers

scientific article published on 08 March 2019

Molecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenografts

scientific article

Molecular methods for somatic mutation testing in lung adenocarcinoma: EGFR and beyond

scientific article

Molecular profiling in colorectal cancer: current state of play and future directions

scientific article published in February 2014

More About: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma

scientific article published on 01 January 2000

Mucinous sweat-gland adenocarcinoma of the eyelid

scientific article published on 01 January 1992

Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer

scientific article published on 10 November 2020

Multiomics medicine in oncology: assessing effectiveness, cost-effectiveness and future research priorities for the molecularly unique individual.

scientific article published on September 2013

Multiplexed transcriptome analysis to detect ALK, ROS1 and RET rearrangements in lung cancer

scientific article published on 09 February 2017

Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations

scientific article

Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women

scientific article published on 7 December 2013

National Working Group Meeting on ALK diagnostics in lung cancer.

scientific article

Natural history of prostate cancer

scientific article published in The Lancet

Neoadjuvant Model in Cancer Treatment: From Clinical Opportunity to Health-Care Utility

scientific article published in May 2015

No evidence for DNA methylation of von Hippel-Lindau ubiquitin ligase complex genes in breast cancer

scientific article published on 3 August 2010

No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer

scientific article

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

scientific article published on 13 April 2008

Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms.

scientific article published on August 1994

Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

scientific article

Nuclear HIF1A expression is strongly prognostic in sporadic but not familial male breast cancer

scientific article published on 24 January 2014

Nuclear and cytoplasmic expressions of ERβ1 and ERβ2 are predictive of response to therapy and alters prognosis in familial breast cancers.

scientific article published on 20 May 2010

Nuclear localization of factor inhibitor hypoxia-inducible factor in prostate cancer is associated with poor prognosis.

scientific article published on 22 February 2011

Oestrogen receptor and epidermal growth factor receptor expression in male breast carcinoma

scientific article published in January 1992

PIK3CA mutations are frequently observed in BRCAX but not BRCA2-associated male breast cancer

scientific article published on January 2013

PROGNOSTIC VALUE OF ANGIOGENESIS IN OPERABLE NON-SMALL CELL LUNG CANCER

scientific article published on 01 May 1996

PathOS: a decision support system for reporting high throughput sequencing of cancers in clinical diagnostic laboratories

scientific article

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications

Phosphorylated ERalpha, HIF-1alpha, and MAPK signaling as predictors of primary endocrine treatment response and resistance in patients with breast cancer

scientific article published on 8 December 2008

Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus

scientific article published in March 2004

Phyllodes tumours of the breast: a consensus review

scientific article

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

scientific article published on 12 May 2020

Plasminogen activator inhibitor-1 as a measure of vascular remodelling in breast cancer

scientific article

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: An immunohistochemical study

scientific article published on 01 June 1995

Positron Emission Tomography and Neoadjuvant Therapy of Breast Cancer

scientific article published on 01 January 2011

Precision oncology using a clinician-directed, tailored approach to molecular profiling.

scientific article published on 30 October 2017

Predictive Immunohistochemical Biomarkers in the Context of Neoadjuvant Therapy for Breast Cancer

scientific article published on 01 January 2011

Preoperative β-Blockade with Propranolol Reduces Biomarkers of Metastasis in Breast Cancer: A Phase II Randomized Trial

scientific article published on 21 November 2019

Profound MEK inhibitor response in a cutaneous melanoma harboring a GOLGA4-RAF1 fusion

scientific article published on 05 March 2019

Prognostic significance of PD-L1+ and CD8+ immune cells in HPV+ oropharyngeal squamous cell carcinoma

scientific article published on 29 January 2018

Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial

scientific article

Prognostic value of c-erbB-2 and epidermal growth factor receptor in stage A1 (Tla) prostatic adenocarcinoma

scientific article published on 01 August 1994

Publisher Correction: CNspector: a web-based tool for visualisation and clinical diagnosis of copy number variation from next generation sequencing

scientific article published on 23 June 2020

Publisher Correction: Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

scientific article published on 01 December 2018

Pure anti-tumor effect of zoledronic acid in naïve bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy".

scientific article published on 28 January 2014

Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection

scientific article published on 12 April 2007

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

scientific article published on 01 December 2006

Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation

scientific article published on December 1996

Quantification of angiongenesis as an independent predictor of prognosis in invasive bladder carcinomas

scientific article published on 01 December 1994

Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis

article

Quantitative angiogenesis in breast cancer

scientific article published on 01 January 2006

RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.

scientific article published on 18 February 2014

RAD21 overexpression is frequently observed in BRCA-X Prostate Cancers

article

RAF1 rearrangements are common in pancreatic acinar cell carcinomas

scientific article published on 01 May 2020

RANKL-dependent and RANKL-independent mechanisms of macrophage-osteoclast differentiation in breast cancer

scientific article published on 07 December 2006

Randomized Phase II Trial of Letrozole and Letrozole Plus Low-Dose Metronomic Oral Cyclophosphamide As Primary Systemic Treatment in Elderly Breast Cancer Patients

scientific article published on 01 August 2006

Rapid detection of carriers with BRCA1 and BRCA2 mutations using high resolution melting analysis

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Rare germline copy number variants (CNVs) and breast cancer risk

scientific article published on 18 January 2022

Re: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma

scientific article published on 01 December 1995

Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers.

scientific article published on 26 April 2011

Recurrent SPECC1L-NTRK fusions in paediatric sarcoma and brain tumours

scientific article published on 03 November 2020

Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer

scientific article published on 10 January 2017

Regulation of hepatocyte growth factor activator inhibitor 2 by hypoxia in breast cancer

scientific article published on January 2007

Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma

scientific article published on 5 April 2011

Relationship of elevated tumour thymidine phosphorylase in node-positive breast carcinomas to the effects of adjuvant CMF

scientific article published on 01 March 1997

Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer

scientific article published on 01 September 1993

Relationship of the Breast Ductal Carcinoma In Situ Immune Microenvironment with Clinicopathological and Genetic Features

scientific article published on 13 June 2017

Relationship of vascular maturation in breast cancer blood vessels to vascular density and metastasis, assessed by expression of a novel basement membrane component, LH39.

scientific article published on February 2000

Reply to the Baader-Meinhof phenomenon in ductal carcinomain situof the breast

scientific article published on 5 May 2016

Response to Editorial: The PD-L1 Immunohistochemistry Biomarker: Two Steps Forward, One Step Back?

scientific article published on 01 September 2018

Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP.

scientific article published on 19 September 2016

Retraction: The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling

scientific article published on 01 June 2019

Role of carbonic anhydrase IX expression in prediction of the efficacy and outcome of primary epirubicin/tamoxifen therapy for breast cancer

scientific article published on 01 September 2006

Role of p53 in the progression of gastric cancer

scientific article published on December 2014

Role of the novel generation of androgen receptor pathway targeted agents in the management of castration-resistant prostate cancer: A literature based meta-analysis of randomized trials

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SDH-deficient renal cell carcinoma associated with biallelic mutation in succinate dehydrogenase A: comprehensive genetic profiling and its relation to therapy response.

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Second international consensus on the methodology and criteria of evaluation of angiogenesis quantification in solid human tumours

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Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer

scientific article published on 26 June 2006

Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

scientific article published on 18 July 2011

Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with T2 to T4, N0 and N1 breast cancer.

scientific article published on 15 July 2016

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing

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Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

scientific article published on 25 June 2018

Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group

scientific article published on July 2016

Subtypes of familial breast tumours revealed by expression and copy number profiling

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Survival difference according to mutation status in a prospective cohort study of Australian patients with metastatic Non-Small Cell Lung Carcinoma (NSCLC).

scientific article published on 24 May 2017

Synergistic activity of letrozole and sorafenib on breast cancer cells

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Systemic endothelial activation occurs in both mild and severe malaria. Correlating dermal microvascular endothelial cell phenotype and soluble cell adhesion molecules with disease severity

scientific article published on June 1998

TUMOUR ANGIOGENESIS

scientific article published on 01 July 1996

Targeting BCL-2–expressing basal-like breast cancer with BH3-mimetics.

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Targeting Mdmx to treat breast cancers with wild-type p53.

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Targeting fibroblast growth factor receptor in breast cancer: a promise or a pitfall?

scientific article published on 20 March 2014

Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization.

scientific article published on 7 June 2013

The 2019 WHO classification of tumours of the breast

scientific article published on 13 February 2020

The Christchurch Tissue Bank to support cancer research

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The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling

scientific article published on 26 May 2016

The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis

scientific article published on 22 August 2013

The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene.

scientific article published on 14 February 2011

The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment

scientific article published on 20 December 2016

The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".

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The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density

scientific article published on 07 August 2020

The androgen receptor is significantly associated with vascular endothelial growth factor and hypoxia sensing via hypoxia-inducible factors HIF-1a, HIF-2a, and the prolyl hydroxylases in human prostate cancer

scientific article published on November 2005

The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium

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The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers.

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The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression

scientific article published on June 2003

The bioreductive prodrug PR-104A is activated under aerobic conditions by human aldo-keto reductase 1C3

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The cancer genetics and pathology of male breast cancer

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The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway.

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The epidermal growth factor receptor as a prognostic marker: results of 370 patients and review of 3009 patients

scientific article published on January 1994

The epidermal growth factor receptor in breast cancer.

scientific article published in April 1997

The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression

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The fibrinolysis inhibitor α2-antiplasmin restricts lymphatic remodelling and metastasis in a mouse model of cancer

scientific article published on 11 July 2017

The genetic architecture of breast papillary lesions as a predictor of progression to carcinoma

scientific article published on 12 March 2020

The genomic landscape of phaeochromocytoma

scientific article published on 2 February 2015

The increased expression of adhesion molecules ICAM-3, E- and P-selectins on breast cancer endothelium

scientific article published on 01 December 1995

The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy.

scientific article published on January 2009

The molecular characterisation of unusual subcutaneous spindle cell lesion of breast

scientific article published on 20 April 2012

The molecular origin and taxonomy of mucinous ovarian carcinoma

scientific article published on 02 September 2019

The number of regulatory T cells in prostate cancer is associated with the androgen receptor and hypoxia-inducible factor (HIF)-2α but not HIF-1α

scientific article published on 01 May 2007

The path to a better biomarker: Application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice

scientific article published on 04 March 2020

The presence of a fibrotic focus in invasive breast carcinoma correlates with the expression of carbonic anhydrase IX and is a marker of hypoxia and poor prognosis

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The prognostic value of quantitative angiogenesis in breast cancer and role of adhesion molecule expression in tumor endothelium

scientific article published on 01 January 1995

The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen

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The short form of the alternatively spliced flt-4 but not its ligand vascular endothelial growth factor C is related to lymph node metastasis in human breast cancers

scientific article published on 01 November 2000

The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers

scientific article published on August 2004

Thymidine phosphorylase is angiogenic and promotes tumor growth.

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Triple negative breast cancers have a reduced expression of DNA repair genes

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Tubular apocrine adenoma and papillary eccrine adenoma. Entities or unity?

scientific article published on 01 April 1992

Tumor angiogenesis in node-negative breast carcinomas ? relationship with epidermal growth factor receptor, estrogen receptor, and survival

scientific article published on 01 January 1994

Tumour angiogenesis and prognosis.

scientific article published on March 1997

Tumour-infiltrating lymphocytes and the emerging role of immunotherapy in breast cancer

scientific article published on 31 December 2016

Tumour-infiltrating lymphocytes in advanced HER2-positive breast cancer treated with pertuzumab or placebo in addition to trastuzumab and docetaxel: a retrospective analysis of the CLEOPATRA study

scientific article published on 06 December 2016

UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas

scientific article published on 15 December 2015

Up-regulation of thymidine phosphorylase expression is associated with a discrete pattern of angiogenesis in ductal carcinomasin situ of the breast

scientific article published on 01 August 1997

Upregulation of basic fibroblast growth factor in breast carcinoma and its relationship to vascular density, oestrogen receptor, epidermal growth factor receptor and survival

scientific article published on 01 June 1999

VEGF-B expression in human primary breast cancers is associated with lymph node metastasis but not angiogenesis.

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VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury

scientific article published on 29 February 2016

VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium

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Vascular endothelial growth factor (VEGF)-A and platelet-derived growth factor (PDGF) play a central role in the pathogenesis of digital clubbing

scientific article published on June 2004

Vascular endothelial growth factor-B and vascular endothelial growth factor-C expression in renal cell carcinomas: regulation by the von Hippel-Lindau gene and hypoxia.

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Where and by whom should gastric cancer HER2/neu status be assessed?: lessons from breast cancer.

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Would the combination of everolimus with endocrine-therapy help in FGFR2 positive serous endometrial cancer?

scientific article published on 5 June 2015

c-Myc interacts with hypoxia to induce angiogenesis in vivo by a vascular endothelial growth factor-dependent mechanism

scientific article published in September 2004

kConFab: A Familial Breast Cancer Consortium Facilitating Research and Translational Oncology

scientific article published on 01 January 2011

p53 and c-myc expression in stage A1 prostatic adenocarcinoma: useful prognostic determinants?

scientific article published in August 1993

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