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List of works by Makrina Totsika

A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131.

scientific article published on 03 June 2013

A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

scientific article published on 19 July 2017

Antivirulence DsbA inhibitors attenuate <i>Salmonella enterica</i> serovar Typhimurium fitness without detectable resistance

scientific article published on 10 February 2021

Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA

scientific article

Autotransporters of Escherichia coli: a sequence-based characterization

scientific article published on 6 May 2010

Chaperone-usher fimbriae of Escherichia coli

scientific article

Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance.

scientific article

Characterization of EhaJ, a New Autotransporter Protein from Enterohemorrhagic and Enteropathogenic Escherichia coli

scientific article

Characterization of two homologous disulfide bond systems involved in virulence factor biogenesis in uropathogenic Escherichia coli CFT073.

scientific article published on 17 April 2009

Comparative analysis of FimB and FimE recombinase activity

scientific article

Comparative analysis of the uropathogenic Escherichia coli surface proteome by tandem mass-spectrometry of artificially induced outer membrane vesicles

scientific article published on 20 December 2014

Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells

scientific article

Comprehensive analysis of type 1 fimbriae regulation in fimB-null strains from the multidrug resistant Escherichia coli ST131 clone

scientific article

Conserved FimH mutations in the global Escherichia coli ST131 multi-drug resistant lineage weaken interdomain interactions and alter adhesin function

scientific article published in 2022

Contribution of siderophore systems to growth and urinary tract colonization of asymptomatic bacteriuria Escherichia coli

scientific article published on 19 September 2011

DSB proteins and bacterial pathogenicity.

scientific article published on 09 February 2009

Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli

scientific article published in April 2006

Differential Afa/Dr Fimbriae Expression in the Multidrug-Resistant Escherichia coli ST131 Clone

scientific article published in 2022

Differential Regulation of the Surface-Exposed and Secreted SslE Lipoprotein in Extraintestinal Pathogenic Escherichia coli

scientific article

Discovery of an archetypal protein transport system in bacterial outer membranes.

scientific article

Eradicating uropathogenic Escherichia coli biofilms with a ciprofloxacin-dinitroxide conjugate

scientific article published on 25 February 2019

Escherichia coli 83972 expressing a P fimbriae oligosaccharide receptor mimic impairs adhesion of uropathogenic E. coli.

scientific article

Escherichia coli isolates causing asymptomatic bacteriuria in catheterized and noncatheterized individuals possess similar virulence properties

scientific article

Experimental colonization of the canine urinary tract with the asymptomatic bacteriuria Escherichia coli strain 83972.

scientific article published on 17 June 2010

Expression and crystallization of SeDsbA, SeDsbL and SeSrgA from Salmonella enterica serovar Typhimurium

scientific article

F9 fimbriae of uropathogenic Escherichia coli are expressed at low temperature and recognise Galβ1-3GlcNAc-containing glycans

scientific article

Functional heterogeneity of the UpaH autotransporter protein from uropathogenic Escherichia coli

scientific article

Global dissemination of a multidrug resistant Escherichia coli clone

scientific article published on 31 March 2014

Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection

scientific article published on May 2012

Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract infection

scientific article published on 19 December 2011

Insights into a multidrug resistant Escherichia coli pathogen of the globally disseminated ST131 lineage: genome analysis and virulence mechanisms

scientific article

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

scientific article published on 24 May 2011

Loss of β-Ketoacyl Acyl Carrier Protein Synthase III Activity Restores Multidrug-Resistant Escherichia coli Sensitivity to Previously Ineffective Antibiotics

scientific article published in 2022

Molecular Characterization of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli

scientific article published on 8 February 2016

Molecular analysis of asymptomatic bacteriuria Escherichia coli strain VR50 reveals adaptation to the urinary tract by gene acquisition

scientific article

Molecular analysis of the Acinetobacter baumannii biofilm-associated protein

scientific article published on 16 August 2013

Molecular analysis of type 3 fimbrial genes from Escherichia coli, Klebsiella and Citrobacter species

scientific article published in 2010

Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections

scientific article published on 21 December 2011

Molecular characterization of UpaB and UpaC, two new autotransporter proteins of uropathogenic Escherichia coli CFT073.

scientific article published on 19 September 2011

Molecular characterization of endocarditis-associated Staphylococcus aureus

scientific article published on 24 April 2013

Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli

scientific article published on 27 January 2012

Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding

scientific article published on 22 February 2019

Muramidases found in the foregut microbiome of the Tammar wallaby can direct cell aggregation and biofilm formation.

scientific article

Nitroxide Functionalized Antibiotics Are Promising Eradication Agents against Staphylococcus aureus Biofilms

scientific article published on 20 December 2019

Phage library screening for the rapid identification and in vivo testing of candidate genes for a DNA vaccine against Mycoplasma mycoides subsp. mycoides small colony biotype

scientific article published in January 2006

Profluorescent Fluoroquinolone-Nitroxides for Investigating Antibiotic⁻Bacterial Interactions

scientific article published on 04 March 2019

Regulation of P-fimbrial phase variation frequencies in Escherichia coli CFT073.

scientific article published on 23 April 2007

Regulatory interplay between pap operons in uropathogenic Escherichia coli

scientific article published on 14 January 2008

Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli

scientific article

Sortase A: an ideal target for anti-virulence drug development

scientific article

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli

scientific article

Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar Typhimurium

scientific article

Structure and function of DsbA, a key bacterial oxidative folding catalyst

scientific article published on 17 January 2011

Structure of a bacterial self-associating protein

The Escherichia coli O157:H7 EhaB autotransporter protein binds to laminin and collagen I and induces a serum IgA response in O157:H7 challenged cattle

scientific article

The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping

scientific article

The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions

scientific article published on 24 January 2015

The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b:H4-ST131 clone.

scientific article

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection.

scientific article published on 21 October 2016

The role of H4 flagella in Escherichia coli ST131 virulence

scientific article

The saliva microbiome profiles are minimally affected by collection method or DNA extraction protocols.

scientific article published on 17 August 2017

The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone.

scientific article

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity

scientific article published on 21 February 2022

UafB is a serine-rich repeat adhesin of Staphylococcus saprophyticus that mediates binding to fibronectin, fibrinogen and human uroepithelial cells

scientific article published on 20 January 2011

UpaG, a new member of the trimeric autotransporter family of adhesins in uropathogenic Escherichia coli

scientific article

UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073

scientific article

Uropathogenic Escherichia coli mediated urinary tract infection.

scientific article published on October 2012

Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection

scientific article published on 08 February 2013

Virulence properties of asymptomatic bacteriuria Escherichia coli

scientific article published on 15 August 2008

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