List of works - Rohan A. Davis

(+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp

article

(-)-Dibromophakellin: an alpha2B adrenoceptor agonist isolated from the Australian marine sponge, Acanthella costata ⬇️

scientific article

1H and13C NMR assignments for two new xanthones from the endophytic fungusXylaria sp. FRR 5657

scientific article published on 06 July 2006

6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.

scientific article published on 19 October 2016

7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata.

scientific article published on 25 May 2010

A bastadin with potent and selective delta-opioid receptor binding affinity from the Australian sponge Ianthella flabelliformis.

scientific article published in June 2010

A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature

scientific article published on 14 August 2017

A new quinoline epoxide from the Australian plant Drummondita calida ⬇️

scientific article

Acaricidal activity of eugenol based compounds against scabies mites

scientific article

Alkaloids from the Chinese vine Gnetum montanum ⬇️

scientific article

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.

scientific article published on 29 December 2015

Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca.

scientific article published on 18 April 2013

Antimalarial activity of azafluorenone alkaloids from the Australian tree Mitrephora diversifolia ⬇️

scientific article published in August 2009

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp. ⬇️

scientific article

Antimalarial benzylisoquinoline alkaloid from the rainforest tree Doryphora sassafras ⬇️

scientific article published in August 2009

Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp. ⬇️

scientific article

Antitrypanosomal cyclic polyketide peroxides from the Australian marine sponge Plakortis sp.

scientific article published in April 2010

Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis

scientific article published on 27 April 2016

Caelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian Aplidium caelestis ⬇️

scientific article published in September 2010

Capillasterin A, a Novel Pyrano[2,3-f]chromene from the Australian Crinoid

article

Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library

scientific article

Celastrofurans A-G: Dihydro-β-agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells

scientific article

Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284

scientific article

Chemoinformatic analysis as a tool for prioritization of trypanocidal marine derived lead compounds

scientific article published on 04 March 2014

Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa

scientific article

Clavatadines C-E, guanidine alkaloids from the Australian sponge Suberea clavata.

scientific article published in May 2009

Comatulins A-E, Taurine-Conjugated Anthraquinones from the Australian Crinoid Comatula rotalaria

scientific article published on 01 June 2020

Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa.

scientific article

Crinoids: ancient organisms, modern chemistry.

scientific article published on 30 March 2017

Cytotoxic C20 Diterpenoid Alkaloids from the Australian Endemic Rainforest Plant Anopterus macleayanus

scientific article published on 24 November 2015

Defining the targets of antiparasitic compounds.

scientific article

Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain

scientific article published on 7 July 2017

Denhaminols A-H, dihydro-β-agarofurans from the endemic Australian rainforest plant Denhamia celastroides. ⬇️

scientific article

Design and Synthesis of a Screening Library Using the Natural Product Scaffold 3-Chloro-4-hydroxyphenylacetic Acid

scientific article published on 24 March 2015

Design and synthesis of screening libraries based on the muurolane natural product scaffold.

scientific article

Design, synthesis and spectroscopic characterisation of a focused library based on the polyandrocarpamine natural product scaffold

scientific article

Determination of analyte concentration using the residual solvent resonance in (1)H NMR spectroscopy.

scientific article

Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c

scientific article published on 12 May 2017

Differential effects of tissue culture coating substrates on prostate cancer cell adherence, morphology and behavior

scientific article

Dihydro-β-agarofurans from the Australian rainforest plant Denhamia celastroides that inhibit leucine transport in prostate cancer cells

article

Dihydro-β-agarofurans from the roots of the Australian endemic rainforest tree Maytenus bilocularis act as leucine transport inhibitors.

scientific article published on 30 January 2018

Discovery of Thalicthuberine as a Novel Antimitotic Agent from Nature that Disrupts Microtubule Dynamics and Induces Apoptosis in Prostate Cancer Cells.

scientific article

Drug-like properties: guiding principles for the design of natural product libraries.

scientific article

Endiandrin A, a Potent Glucocorticoid Receptor Binder Isolated from the Australian PlantEndiandraanthropophagorum ⬇️

article

Entonalactams A-C: Isoindolinone derivatives from an Australian rainforest fungus belonging to the genus Entonaema.

scientific article published on 3 June 2015

Front-loading natural-product-screening libraries for log P: background, development, and implementation

scientific article

Guiding principles for natural product drug discovery

scientific article

Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis. ⬇️

scientific article

Identification of Fromiamycalin and Halaminol A from Australian Marine Sponge Extracts with Anthelmintic Activity against Haemonchus contortus

scientific article published on 23 October 2019

Identification of Gibberellic Acid Derivatives That Deregulate Cholesterol Metabolism in Prostate Cancer Cells.

scientific article published on 23 February 2018

Identification of eusynstyelamide B as a potent cell cycle inhibitor following the generation and screening of an ascidian-derived extract library using a real time cell analyzer.

scientific article published on 17 October 2014

Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp. ⬇️

scientific article published on 17 May 2012

Isolation, structure determination and cytotoxicity studies of tryptophan alkaloids from an Australian marine sponge Hyrtios sp. ⬇️

scientific article

Lepadins F-H, new cis-decahydroquinoline alkaloids from the Australian ascidian Aplidium tabascum.

scientific article published in April 2002

Marine natural products

scientific article published on 01 February 2020

Marine natural products

scientific article published on 01 January 2018

Marine natural products

scientific article published on 21 January 2019

Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.

scientific article

Microthecaline A, a Quinoline Serrulatane Alkaloid from the Roots of the Australian Desert Plant Eremophila microtheca.

scientific article published on 13 March 2018

Mitchellenes A–E, Cyclic Sesquiterpenes from the Australian PlantEremophila mitchellii ⬇️

scientific article published on 23 September 2011

N-Benzyl-2-(3-chloro-4-hy-droxy-phen-yl)acetamide

scientific article

Natural product coumarins that inhibit human carbonic anhydrases

scientific article

Natural product polyamines that inhibit human carbonic anhydrases.

scientific article published on 5 August 2014

Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases

scientific article

Natural products that inhibit carbonic anhydrase

scientific article published on January 2014

New galloylated flavanonols from the Australian plant Glochidion sumatranum. ⬇️

scientific article published in July 2010

New lamellarin alkaloids from the australian ascidian, didemnum chartaceum

scientific article published on 01 March 1999

Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp. ⬇️

scientific article

Pim2 inhibitors from the Papua New Guinean plant Cupaniopsis macropetala

scientific article published on 29 December 2007

Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.

scientific article

Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning.

scientific article

Psammaplysin H, a new antimalarial bromotyrosine alkaloid from a marine sponge of the genus Pseudoceratina.

scientific article published on 21 November 2010

Psammaplysin derivatives from the Balinese marine sponge Aplysinella strongylata

scientific article

Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.

scientific article published on 17 August 2011

Pteridine-, thymidine-, choline- and imidazole-derived alkaloids from the Australian ascidian, Leptoclinides durus

scientific article published on 19 November 2012

Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis ⬇️

scientific article published on 16 November 2012

Reaction of Papaverine with Baran DiversinatesTM

scientific article published on 31 October 2019

Red Fluorescent Applied to Live Cell Imaging and Screening for Antibacterial Agents

scientific article published on 18 December 2018

Rhodocomatulin-Type Anthraquinones from the Australian Marine Invertebrates Clathria hirsuta and Comatula rotalaria.

scientific article

Screening a Natural Product-Based Library against Kinetoplastid Parasites.

scientific article published on 12 October 2017

Screening a natural product-based combinatorial library using FTICR mass spectrometry

scientific article

Screening of a small, well-curated natural product-based library identifies two rotenoids with potent nematocidal activity against Haemonchus contortus.

scientific article published on 11 July 2017

Selective protein unfolding: a universal mechanism of action for the development of irreversible inhibitors

scientific article

Semi-synthesis and NMR spectral assignments of flavonoid and chalcone derivatives

scientific article published on 25 July 2016

Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems ⬇️

scientific article

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A-D.

scientific article

Synthesis and antimalarial evaluation of a screening library based on a tetrahydroanthraquinone natural product scaffold

scientific article

Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold

scientific article

Synthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives

scientific article published on 23 July 2011

Synthesis and antiplasmodial evaluation of novel chromeno[2,3-b]chromene derivatives.

scientific article published on 4 January 2012

Synthesis and spectroscopic characterisation of a combinatorial library based on the fungal natural product 3-chloro-4-hydroxyphenylacetamide

scientific article

Synthesis of a Unique Psammaplysin F Library and Functional Evaluation in Prostate Cancer Cells by Multiparametric Quantitative Single Cell Imaging

scientific article published on 21 July 2020

Synthesis of antimalarial amide analogues based on the plant serrulatane diterpenoid 3,7,8-trihydroxyserrulat-14-en-19-oic acid

scientific article published on 15 July 2017

The absolute stereochemistry and cytotoxicity of the ascidian-derived metabolite, longithorone J.

scientific article published on December 2006

The design, synthesis, and anti-inflammatory evaluation of a drug-like library based on the natural product valerenic acid.

scientific article

The diversity and antimicrobial activity of Preussia sp. endophytes isolated from Australian dry rainforests

scientific article

The fungal natural product (1S,3S)-austrocortirubin induces DNA damage in HCT116 cells via a mechanism unique from other DNA damaging agents.

scientific article published on 29 November 2014

The plant-derived glucocorticoid receptor agonist Endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKs

scientific article published in 2012

The resveratrol tetramer (-)-hopeaphenol inhibits type III secretion in the gram-negative pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosa

scientific article published on 4 December 2013

The serrulatane diterpenoid natural products RAD288 and RAD289 stimulate properties of olfactory ensheathing cells useful for neural repair therapies.

scientific article published on 6 July 2018

The use of isolated natural products as scaffolds for the generation of chemically diverse screening libraries for drug discovery

scientific article published on 7 January 2016

Thiaplakortones A-D: antimalarial thiazine alkaloids from the Australian marine sponge Plakortis lita

scientific article

Total synthesis of thiaplakortone a: derivatives as metabolically stable leads for the treatment of malaria

scientific article

Trikentramides A-D, indole alkaloids from the Australian sponge Trikentrion flabelliforme.

scientific article published on 4 November 2013

Type III secretion inhibitors for the management of bacterial plant diseases

scientific article published on 19 October 2018

Unequivocal 13C NMR assignment of cyclohexadienyl rings in bromotyrosine-derived metabolites from marine sponges

scientific article published on 10 September 2012

Using UHPLC-MS Profiling for the Discovery of New Dihydro-β-Agarofurans from Australian Celastraceae Plant Extracts

article

List of works by Rohan A. Davis

(+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp

(-)-Dibromophakellin: an alpha2B adrenoceptor agonist isolated from the Australian marine sponge, Acanthella costata ⬇️

1H and13C NMR assignments for two new xanthones from the endophytic fungusXylaria sp. FRR 5657

6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.

7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata.

A bastadin with potent and selective delta-opioid receptor binding affinity from the Australian sponge Ianthella flabelliformis.

A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature

A new quinoline epoxide from the Australian plant Drummondita calida ⬇️

Acaricidal activity of eugenol based compounds against scabies mites

Alkaloids from the Chinese vine Gnetum montanum ⬇️

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.

Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca.

Antimalarial activity of azafluorenone alkaloids from the Australian tree Mitrephora diversifolia ⬇️

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp. ⬇️

Antimalarial benzylisoquinoline alkaloid from the rainforest tree Doryphora sassafras ⬇️

Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp. ⬇️

Antitrypanosomal cyclic polyketide peroxides from the Australian marine sponge Plakortis sp.

Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis

Caelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian Aplidium caelestis ⬇️

Capillasterin A, a Novel Pyrano[2,3-f]chromene from the Australian Crinoid

Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library

Celastrofurans A-G: Dihydro-β-agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells

Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284

Chemoinformatic analysis as a tool for prioritization of trypanocidal marine derived lead compounds

Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa

Clavatadines C-E, guanidine alkaloids from the Australian sponge Suberea clavata.

Comatulins A-E, Taurine-Conjugated Anthraquinones from the Australian Crinoid Comatula rotalaria

Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa.

Crinoids: ancient organisms, modern chemistry.

Cytotoxic C20 Diterpenoid Alkaloids from the Australian Endemic Rainforest Plant Anopterus macleayanus

Defining the targets of antiparasitic compounds.

Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain

Denhaminols A-H, dihydro-β-agarofurans from the endemic Australian rainforest plant Denhamia celastroides. ⬇️

Design and Synthesis of a Screening Library Using the Natural Product Scaffold 3-Chloro-4-hydroxyphenylacetic Acid

Design and synthesis of screening libraries based on the muurolane natural product scaffold.

Design, synthesis and spectroscopic characterisation of a focused library based on the polyandrocarpamine natural product scaffold

Determination of analyte concentration using the residual solvent resonance in (1)H NMR spectroscopy.

Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c

Differential effects of tissue culture coating substrates on prostate cancer cell adherence, morphology and behavior

Dihydro-β-agarofurans from the Australian rainforest plant Denhamia celastroides that inhibit leucine transport in prostate cancer cells

Dihydro-β-agarofurans from the roots of the Australian endemic rainforest tree Maytenus bilocularis act as leucine transport inhibitors.

Discovery of Thalicthuberine as a Novel Antimitotic Agent from Nature that Disrupts Microtubule Dynamics and Induces Apoptosis in Prostate Cancer Cells.

Drug-like properties: guiding principles for the design of natural product libraries.

Endiandrin A, a Potent Glucocorticoid Receptor Binder Isolated from the Australian PlantEndiandraanthropophagorum ⬇️

Entonalactams A-C: Isoindolinone derivatives from an Australian rainforest fungus belonging to the genus Entonaema.

Front-loading natural-product-screening libraries for log P: background, development, and implementation

Guiding principles for natural product drug discovery

Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis. ⬇️

Identification of Fromiamycalin and Halaminol A from Australian Marine Sponge Extracts with Anthelmintic Activity against Haemonchus contortus

Identification of Gibberellic Acid Derivatives That Deregulate Cholesterol Metabolism in Prostate Cancer Cells.

Identification of eusynstyelamide B as a potent cell cycle inhibitor following the generation and screening of an ascidian-derived extract library using a real time cell analyzer.

Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp. ⬇️

Isolation, structure determination and cytotoxicity studies of tryptophan alkaloids from an Australian marine sponge Hyrtios sp. ⬇️

Lepadins F-H, new cis-decahydroquinoline alkaloids from the Australian ascidian Aplidium tabascum.

Marine natural products

Marine natural products

Marine natural products

Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.

Microthecaline A, a Quinoline Serrulatane Alkaloid from the Roots of the Australian Desert Plant Eremophila microtheca.

Mitchellenes A–E, Cyclic Sesquiterpenes from the Australian PlantEremophila mitchellii ⬇️

N-Benzyl-2-(3-chloro-4-hy-droxy-phen-yl)acetamide

Natural product coumarins that inhibit human carbonic anhydrases

Natural product polyamines that inhibit human carbonic anhydrases.

Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases

Natural products that inhibit carbonic anhydrase

New galloylated flavanonols from the Australian plant Glochidion sumatranum. ⬇️

New lamellarin alkaloids from the australian ascidian, didemnum chartaceum

Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp. ⬇️

Pim2 inhibitors from the Papua New Guinean plant Cupaniopsis macropetala

Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.

Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning.

Psammaplysin H, a new antimalarial bromotyrosine alkaloid from a marine sponge of the genus Pseudoceratina.

Psammaplysin derivatives from the Balinese marine sponge Aplysinella strongylata

Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.

Pteridine-, thymidine-, choline- and imidazole-derived alkaloids from the Australian ascidian, Leptoclinides durus

Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis ⬇️

Reaction of Papaverine with Baran DiversinatesTM

Red Fluorescent Applied to Live Cell Imaging and Screening for Antibacterial Agents

Rhodocomatulin-Type Anthraquinones from the Australian Marine Invertebrates Clathria hirsuta and Comatula rotalaria.