List of works - Adeel Safdar

A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms

scientific article

Acute endurance exercise increases the nuclear abundance of PGC-1alpha in trained human skeletal muscle.

scientific article published on 27 January 2010

Adipose-brain crosstalk: do adipokines have a role in neuroprotection?

scientific article published on September 2015

Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis

scientific article

Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise

scientific article

Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS.

scientific article

Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults

scientific article

Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice.

scientific article

Effect of sex on the acute skeletal muscle response to sprint interval exercise.

scientific article published on 24 January 2017

Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men.

scientific article published on 18 February 2015

Endothelial PGC-1α mediates vascular dysfunction in diabetes.

scientific article

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

scientific article

Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis.

scientific article

Exercise-induced histone acetylation - playing tag with the genome

scientific article published on 01 March 2010

Exosomes as Mediators of the Systemic Adaptations to Endurance Exercise.

scientific article published on 10 May 2017

Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation.

scientific article published on 23 October 2007

Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor γ coactivator (PGC)-1α.

scientific article published on 06 February 2014

Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes

scientific article published on 25 August 2011

Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity

scientific article

Markers of skeletal muscle mitochondrial function and lipid accumulation are moderately associated with the homeostasis model assessment index of insulin resistance in obese men

scientific article (publication date: 2013)

Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain

scientific article

Polymerase gamma mutator mice rely on increased glycolytic flux for energy production.

scientific article published on 6 January 2015

RETRACTED ARTICLE:Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice

retracted scientific article published on January 2015

Retraction Note to: Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice

Running forward: new frontiers in endurance exercise biology

scientific article

Skeletal muscle and beyond: the role of exercise as a mediator of systemic mitochondrial biogenesis

scientific article published on 02 September 2011

Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice

scientific article

The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure

scientific article published on 03 December 2009

The effect of endurance exercise on both skeletal muscle and systemic oxidative stress in previously sedentary obese men.

scientific article published on 16 September 2013

The order of exercise during concurrent training for rehabilitation does not alter acute genetic expression, mitochondrial enzyme activity or improvements in muscle function

scientific article

The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults

scientific article published on February 2008

The potential of endurance exercise-derived exosomes to treat metabolic diseases.

scientific article published on 27 May 2016

When man got his mtDNA deletions?

scientific article published on 4 June 2014

miRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57Bl/6J male mice

scientific article

List of works by Adeel Safdar

A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms

Acute endurance exercise increases the nuclear abundance of PGC-1alpha in trained human skeletal muscle.

Adipose-brain crosstalk: do adipokines have a role in neuroprotection?

Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis

Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise

Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS.

Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults

Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice.

Effect of sex on the acute skeletal muscle response to sprint interval exercise.

Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men.

Endothelial PGC-1α mediates vascular dysfunction in diabetes.

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis.

Exercise-induced histone acetylation - playing tag with the genome

Exosomes as Mediators of the Systemic Adaptations to Endurance Exercise.

Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation.

Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor γ coactivator (PGC)-1α.

Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes

Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity

Markers of skeletal muscle mitochondrial function and lipid accumulation are moderately associated with the homeostasis model assessment index of insulin resistance in obese men

Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain

Polymerase gamma mutator mice rely on increased glycolytic flux for energy production.

RETRACTED ARTICLE:Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice

Retraction Note to: Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice

Running forward: new frontiers in endurance exercise biology

Skeletal muscle and beyond: the role of exercise as a mediator of systemic mitochondrial biogenesis

Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice

The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure

The effect of endurance exercise on both skeletal muscle and systemic oxidative stress in previously sedentary obese men.

The order of exercise during concurrent training for rehabilitation does not alter acute genetic expression, mitochondrial enzyme activity or improvements in muscle function

The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults

The potential of endurance exercise-derived exosomes to treat metabolic diseases.

When man got his mtDNA deletions?

miRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57Bl/6J male mice