List of works - Kay Grünewald

A 3D cellular context for the macromolecular world.

scientific article

A Technical Introduction to Transmission Electron Microscopy for Soft-Matter: Imaging, Possibilities, Choices, and Technical Developments

scientific article published on 04 March 2020

A cool hybrid approach to the herpesvirus 'life' cycle.

scientific article

A molecular pore spans the double membrane of the coronavirus replication organelle

scientific article published on 06 August 2020

A national facility for biological cryo-electron microscopy

scientific article

A resolution criterion for electron tomography based on cross-validation.

scientific article published in August 2005

Adding a spatial dimension to the proteome

article

Cellular electron cryo tomography and in situ sub-volume averaging reveal the context of microtubule-based processes.

scientific article published on 30 June 2016

Characterization of herpes simplex virus type 1 L-particle assembly and egress in hippocampal neurones by electron cryo-tomography

scientific article

Combined 1H-Detected Solid-State NMR Spectroscopy and Electron Cryotomography to Study Membrane Proteins across Resolutions in Native Environments.

scientific article published on 6 December 2017

Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity

scientific article published on 02 December 2021

Conserved eukaryotic fusogens can fuse viral envelopes to cells

scientific article

Correlative VIS-fluorescence and soft X-ray cryo-microscopy/tomography of adherent cells

scientific article

Correlative in-resin super-resolution and electron microscopy using standard fluorescent proteins

scientific article

Corrigendum: Correlative in-resin super-resolution and electron microscopy using standard fluorescent proteins

scientific article published on 8 March 2016

Critical step-by-step approaches toward correlative fluorescence/soft X-ray cryo-microscopy of adherent mammalian cells

scientific article

Cryo electron tomography of herpes simplex virus during axonal transport and secondary envelopment in primary neurons.

scientific article

Cryo electron tomography of native HIV-1 budding sites

scientific article

Cryo-SOFI enabling low-dose super-resolution correlative light and electron cryo-microscopy

scientific article published on 26 February 2019

Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ

scientific article published in August 2006

Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling

scientific article

Editorial Overview

scientific article published on 01 August 2018

Editorial on Correlative Microscopy

scientific article

Eisosome proteins assemble into a membrane scaffold

scientific article

Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy.

scientific article

Electron cryo-microscopy and single-particle averaging of Rift Valley fever virus: evidence for GN-GC glycoprotein heterodimers

scientific article published on 4 February 2009

Electron cryo-tomography captures macromolecular complexes in native environments

scientific article published on 12 September 2017

Electron cryotomography of Tula hantavirus suggests a unique assembly paradigm for enveloped viruses

scientific article

Extracellular vesicles: a platform for the structure determination of membrane proteins by Cryo-EM.

scientific article

Fluorescence cryo-microscopy: current challenges and prospects

scientific article

Fluorescent protein tagging of adenoviral proteins pV and pIX reveals 'late virion accumulation compartment'

scientific article published on 25 June 2020

HVint: A Strategy for Identifying Novel Protein-Protein Interactions in Herpes Simplex Virus Type 1

scientific article published on 06 July 2016

High-precision correlative fluorescence and electron cryo microscopy using two independent alignment markers

scientific article published on 19 October 2013

Human Adenovirus Type 5 Infection Leads to Nuclear Envelope Destabilization and Membrane Permeability Independently of Adenovirus Death Protein

scientific article published in 2021

Infection of neurons and encephalitis after intracranial inoculation of herpes simplex virus requires the entry receptor nectin-1

scientific article published on 05 October 2009

Insights into bunyavirus architecture from electron cryotomography of Uukuniemi virus

scientific article

Ketocarotenoid biosynthesis outside of plastids in the unicellular green alga Haematococcus pluvialis

scientific article

Microcarriers for high-pressure freezing and cryosectioning of adherent cells

scientific article published in May 2008

Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs.

scientific article

Modeling Flexible Protein Structure With AlphaFold2 and Crosslinking Mass Spectrometry

scientific article published in 2024

Multi-layered control of Galectin-8 mediated autophagy during adenovirus cell entry through a conserved PPxY motif in the viral capsid

scientific article

Multimodal nanoparticles as alignment and correlation markers in fluorescence/soft X-ray cryo-microscopy/tomography of nucleoplasmic reticulum and apoptosis in mammalian cells

scientific article published on 3 June 2014

Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry

scientific article

Native structure of a retroviral envelope protein and its conformational change upon interaction with the target cell.

scientific article published on 23 June 2016

Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop

scientific article published on 18 June 2015

Phytoene Desaturase Is Localized Exclusively in the Chloroplast and Up-Regulated at the mRNA Level during Accumulation of Secondary Carotenoids in Haematococcus pluvialis (Volvocales, Chlorophyceae)

scientific article published on 01 April 2000

Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding

scientific article

Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry.

scientific article

Protein interactions and consensus clustering analysis uncover insights into herpesvirus virion structure and function relationships

scientific article published on 14 June 2019

Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells

scientific article

Structural Basis of Vesicle Formation at the Inner Nuclear Membrane

scientific article published in December 2015

Structure of complex viruses and virus-infected cells by electron cryo tomography

scientific article published on 10 July 2006

Super-resolution microscopy using standard fluorescent proteins in intact cells under cryo-conditions

scientific article published on 4 June 2014

Targeting of viral capsids to nuclear pores in a cell-free reconstitution system.

scientific article published on 12 September 2014

The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions

scientific article (publication date: 2006)

The Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein Interaction

scientific article

The full-length cell-cell fusogen EFF-1 is monomeric and upright on the membrane.

scientific article

The m74 gene product of murine cytomegalovirus (MCMV) is a functional homolog of human CMV gO and determines the entry pathway of MCMV.

scientific article published on 24 February 2010

The nucleocapsid domain of Gag is dispensable for actin incorporation into HIV-1 and for association of viral budding sites with cortical F-actin.

scientific article

The prefusion structure of herpes simplex virus glycoprotein B

scientific article published on 25 September 2020

The three-dimensional organization of polyribosomes in intact human cells

scientific article

The use of sonicated lipid vesicles for mass spectrometry of membrane protein complexes

scientific article published on 01 April 2020

Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis

scientific article

Three-dimensional structure of herpes simplex virus from cryo-electron tomography

scientific article

Towards correlative super-resolution fluorescence and electron cryo-microscopy

scientific article published on 26 May 2016

Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein B.

scientific article published on 24 March 2016

Viral fusion: how Flu induces dimples on liposomes

scientific article

List of works by Kay Grünewald

A 3D cellular context for the macromolecular world.

A Technical Introduction to Transmission Electron Microscopy for Soft-Matter: Imaging, Possibilities, Choices, and Technical Developments

A cool hybrid approach to the herpesvirus 'life' cycle.

A molecular pore spans the double membrane of the coronavirus replication organelle

A national facility for biological cryo-electron microscopy

A resolution criterion for electron tomography based on cross-validation.

Adding a spatial dimension to the proteome

Cellular electron cryo tomography and in situ sub-volume averaging reveal the context of microtubule-based processes.

Characterization of herpes simplex virus type 1 L-particle assembly and egress in hippocampal neurones by electron cryo-tomography

Combined 1H-Detected Solid-State NMR Spectroscopy and Electron Cryotomography to Study Membrane Proteins across Resolutions in Native Environments.

Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity

Conserved eukaryotic fusogens can fuse viral envelopes to cells

Correlative VIS-fluorescence and soft X-ray cryo-microscopy/tomography of adherent cells

Correlative in-resin super-resolution and electron microscopy using standard fluorescent proteins

Corrigendum: Correlative in-resin super-resolution and electron microscopy using standard fluorescent proteins

Critical step-by-step approaches toward correlative fluorescence/soft X-ray cryo-microscopy of adherent mammalian cells

Cryo electron tomography of herpes simplex virus during axonal transport and secondary envelopment in primary neurons.

Cryo electron tomography of native HIV-1 budding sites

Cryo-SOFI enabling low-dose super-resolution correlative light and electron cryo-microscopy

Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ

Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling

Editorial Overview

Editorial on Correlative Microscopy

Eisosome proteins assemble into a membrane scaffold

Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy.

Electron cryo-microscopy and single-particle averaging of Rift Valley fever virus: evidence for GN-GC glycoprotein heterodimers

Electron cryo-tomography captures macromolecular complexes in native environments

Electron cryotomography of Tula hantavirus suggests a unique assembly paradigm for enveloped viruses

Extracellular vesicles: a platform for the structure determination of membrane proteins by Cryo-EM.

Fluorescence cryo-microscopy: current challenges and prospects

Fluorescent protein tagging of adenoviral proteins pV and pIX reveals 'late virion accumulation compartment'

HVint: A Strategy for Identifying Novel Protein-Protein Interactions in Herpes Simplex Virus Type 1

High-precision correlative fluorescence and electron cryo microscopy using two independent alignment markers

Human Adenovirus Type 5 Infection Leads to Nuclear Envelope Destabilization and Membrane Permeability Independently of Adenovirus Death Protein

Infection of neurons and encephalitis after intracranial inoculation of herpes simplex virus requires the entry receptor nectin-1

Insights into bunyavirus architecture from electron cryotomography of Uukuniemi virus

Ketocarotenoid biosynthesis outside of plastids in the unicellular green alga Haematococcus pluvialis

Microcarriers for high-pressure freezing and cryosectioning of adherent cells

Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs.

Modeling Flexible Protein Structure With AlphaFold2 and Crosslinking Mass Spectrometry

Multi-layered control of Galectin-8 mediated autophagy during adenovirus cell entry through a conserved PPxY motif in the viral capsid

Multimodal nanoparticles as alignment and correlation markers in fluorescence/soft X-ray cryo-microscopy/tomography of nucleoplasmic reticulum and apoptosis in mammalian cells

Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry

Native structure of a retroviral envelope protein and its conformational change upon interaction with the target cell.

Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop

Phytoene Desaturase Is Localized Exclusively in the Chloroplast and Up-Regulated at the mRNA Level during Accumulation of Secondary Carotenoids in Haematococcus pluvialis (Volvocales, Chlorophyceae)

Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding

Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry.

Protein interactions and consensus clustering analysis uncover insights into herpesvirus virion structure and function relationships

Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells

Structural Basis of Vesicle Formation at the Inner Nuclear Membrane

Structure of complex viruses and virus-infected cells by electron cryo tomography

Super-resolution microscopy using standard fluorescent proteins in intact cells under cryo-conditions

Targeting of viral capsids to nuclear pores in a cell-free reconstitution system.

The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions

The Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein Interaction

The full-length cell-cell fusogen EFF-1 is monomeric and upright on the membrane.

The m74 gene product of murine cytomegalovirus (MCMV) is a functional homolog of human CMV gO and determines the entry pathway of MCMV.

The nucleocapsid domain of Gag is dispensable for actin incorporation into HIV-1 and for association of viral budding sites with cortical F-actin.

The prefusion structure of herpes simplex virus glycoprotein B

The three-dimensional organization of polyribosomes in intact human cells

The use of sonicated lipid vesicles for mass spectrometry of membrane protein complexes

Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis

Three-dimensional structure of herpes simplex virus from cryo-electron tomography

Towards correlative super-resolution fluorescence and electron cryo-microscopy

Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein B.

Viral fusion: how Flu induces dimples on liposomes