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List of works by Geoffrey W Abbott

1,4-Diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers

scientific article published on 29 November 2005

A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance

scientific article published on 4 October 2007

Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death

scientific article published in March 2003

Cardiac arrhythmia and thyroid dysfunction: a novel genetic link

scientific article

Cardioprotective effect of histamine H3-receptor activation: pivotal role of G beta gamma-dependent inhibition of voltage-operated Ca2+ channels

scientific article published on 03 June 2008

Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation

scientific article published on 14 November 2018

Disease-associated mutations in KCNE potassium channel subunits (MiRPs) reveal promiscuous disruption of multiple currents and conservation of mechanism

scientific article (publication date: March 2002)

Dynamical mechanism for subcellular alternans in cardiac myocytes

scientific article published on 23 July 2009

Effects of electrical and structural remodeling on atrial fibrillation maintenance: a simulation study

scientific article

Emerging concepts in the pharmacogenomics of arrhythmias: ion channel trafficking

scientific article

Emulsified isoflurane postconditioning produces cardioprotection against myocardial ischemia-reperfusion injury in rats

scientific article published on 27 April 2013

Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies

scientific article

Genetic dissection reveals unexpected influence of beta subunits on KCNQ1 K+ channel polarized trafficking in vivo

scientific article

HERG biosynthesis: the positive influence of negative charge

scientific article published on 13 March 2009

Impact of ancillary subunits on ventricular repolarization

scientific article

Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.

scientific article published on 20 July 2005

Interaction between soluble and membrane-embedded potassium channel peptides monitored by Fourier transform infrared spectroscopy

scientific article

KCNE Regulation of K(+) Channel Trafficking - a Sisyphean Task?

scientific article

KCNE1 and KCNE2 Provide a Checkpoint Governing Voltage-Gated Potassium Channel α-Subunit Composition ⬇️

scientific article published on September 20, 2011

KCNE1 and KCNE2 inhibit forward trafficking of homomeric N-type voltage-gated potassium channels

scientific article

KCNE2 and the K (+) channel: the tail wagging the dog

scientific article

KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium

scientific article (publication date: December 2011)

KCNEgenetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing? ⬇️

scientific article published on January 1, 2013

KCNQ1 rescues TMC1 plasma membrane expression but not mechanosensitive channel activity

scientific article published on 05 January 2019

Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis

scientific article published in October 2009

MinK-dependent internalization of the IKs potassium channel

scientific article published on 7 February 2009

MinK-related peptide 2 modulates Kv2.1 and Kv3.1 potassium channels in mammalian brain

scientific article

Molecular mechanisms of cardiac voltage-gated potassium channelopathies

scientific article published on January 2006

Pharmacogenetic considerations in diseases of cardiac ion channels

scientific article published on 15 October 2003

Pharmacogenetics and cardiac ion channels

scientific article

Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis

scientific article

Protein kinase C downregulates I(Ks) by stimulating KCNQ1-KCNE1 potassium channel endocytosis

scientific article published on 10 May 2011

RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies

scientific article (publication date: 4 April 2003)

Regulation of the Kv2.1 potassium channel by MinK and MiRP1

scientific article

Remote ischemic preconditioning STAT3-dependently ameliorates pulmonary ischemia/reperfusion injury.

scientific article

Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia

scientific article published in 2010

Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.

scientific article

The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake

scientific article

The MiRP2-Kv3.4 potassium channel: muscling in on Alzheimer's disease

scientific article published on 26 June 2007

The MinK-related peptides

scientific article

The impact of ancillary subunits on small-molecule interactions with voltage-gated potassium channels

scientific article published on January 2006

The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes

scientific article

The ubiquitous flavonoid quercetin is an atypical KCNQ potassium channel activator

scientific article published on 08 July 2020

Transcriptomic analysis reveals atrial KCNE1 down-regulation following lung lobectomy

scientific article

Voltage-dependent C-type inactivation in a constitutively open K+ channel

scientific article published on 20 June 2008

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