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List of works by Ola Hansson

A central role for GRB10 in regulation of islet function in man.

scientific article published on 3 April 2014

A common variant upstream of the PAX6 gene influences islet function in man.

scientific article published on 16 September 2011

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging

scientific article published on 9 October 2015

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

scientific article

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

article

Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice.

scientific article

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

scientific article published on 23 June 2016

Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes.

scientific article

Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness

scientific article (publication date: May 2014)

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes

scientific article published on 7 May 2016

Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity

scientific article

Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a 6-month exercise intervention

article

First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle

article

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

scientific article published on 13 June 2018

Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

scientific article published on 30 September 2020

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

scientific article

Glucose-induced Changes in Gene Expression in Human Pancreatic Islets - Causes or Consequences of Chronic Hyperglycemia

scientific article published on 7 September 2017

HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets

scientific article published in February 2016

HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13.

scientific article

Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL.

scientific article

Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise.

scientific article

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

scientific article published on 23 March 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

scientific article published on 4 January 2016

Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes

scientific article

Inflammatory response in white adipose tissue in the non-obese hormone-sensitive lipase null mouse model

scientific article

Islet Gene View - a tool to facilitate islet research

article

Islet Gene View—a tool to facilitate islet research

scientific article published in 2022

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Less pronounced response to exercise in healthy relatives to type 2 diabetic subjects compared with controls

scientific article published on 3 September 2015

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

scientific article published on January 2014

Link between GIP and osteopontin in adipose tissue and insulin resistance

scientific article published on 24 January 2013

LoFtool: a gene intolerance score based on loss-of-function variants in 60 706 individuals

scientific article

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

scientific article published on 01 November 2019

Low-cost exercise interventions improve long-term cardiometabolic health independently of a family history of type 2 diabetes: a randomized parallel group trial

scientific article published on 01 November 2020

Mapping the Cord Blood Transcriptome of Pregnancies Affected by Early Maternal Anemia to Identify Signatures of Fetal Programming

scientific article published on 01 April 2022

Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes

scientific article published on December 2010

Myocardin Family Members Drive Formation of Caveolae

scientific article

N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism.

scientific article published on 14 February 2018

No Additional Benefits of Block- Over Evenly-Distributed High-Intensity Interval Training within a Polarized Microcycle ⬇️

scientific article

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

scientific article published in March 2018

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

scientific article

PP038. Renal ETK/BMX activation decreased in preeclampsia

scientific article

Photocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.

scientific article published on 21 January 2015

Pleiotropic effects of GIP on islet function involve osteopontin

scientific article

Proteomic studies in animal models of diabetes

scientific article

Relation Between Cycling Exercise Capacity, Fiber-Type Composition, and Lower Extremity Muscle Strength and Muscle Endurance

article

Relationship between insulin sensitivity and gene expression in human skeletal muscle

scientific article published on 27 February 2021

Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes

scientific article

Running with regulation ⬇️

scientific article published on November 11, 2010

Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes

scientific article published on 2 November 2016

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

scientific article

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway

scientific article published on 30 September 2011

TCF7L2 is a master regulator of insulin production and processing

scientific article

Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia

scientific article published on October 2012

The Swedish CArdioPulmonary BioImage Study: objectives and design

scientific article published on 19 June 2015

The TCF7L2-dependent high-voltage activated calcium channel subunit α2δ-1 controls calcium signaling in rodent pancreatic beta-cells

scientific article published on 02 December 2019

The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes

article

The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins

scientific article

Tissue-specific alternative splicing of TCF7L2.

scientific article published on 14 July 2009

Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice

scientific article

Turning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets

scientific article published in 2018

Turning vice into virtue: Using Batch-Effects to Detect Errors in Large Genomic Datasets

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets

scientific article published on 27 February 2009

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