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List of works by Patrick M. Nolan

A comparison of physiological and behavioural parameters in C57BL/6J mice undergoing food or water restriction regimes

scientific article published on 25 July 2006

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

scientific article

A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice

scientific article

A twin and molecular genetics study of sleep paralysis and associated factors

scientific article published on 09 February 2015

Acquisition of a brief behavioral experience in the presence of neuron-specific and D2-CAM/N-CAM-specific antisera

scientific article published in July 1987

Acquisition of a brief behavioural experience in the rat is inhibited by the brain-specific monoclonal antibody, F3-87-8.

scientific article published in August 1987

Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System

scientific article

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

scientific article

Assessing mouse behaviour throughout the light/dark cycle using automated in-cage analysis tools

scientific article published on 26 April 2017

Clocks go forward: progress in the molecular genetic analysis of rhythmic behaviour

scientific article published on 15 January 2009

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

scientific article

Cognitive assessment of mice strains heterozygous for cell-adhesion genes reveals strain-specific alterations in timing

scientific article published on 20 January 2014

Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse model

scientific article published on 25 April 2007

Dibutyryl cyclic AMP stimulates expression of ependymin mRNA and the synthesis and release of the protein into the culture medium by neuroblastoma cells (NB2a/d1).

scientific article

Differential roles for cryptochromes in the mammalian retinal clock

scientific article published on 21 March 2018

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

scientific article

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

scientific article

Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.

scientific article

Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features

scientific article

ENU mutagenesis in the mouse: application to human genetic disease

scientific article published in October 2002

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.

scientific article published on 22 February 2016

Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation.

scientific article published on 13 January 2014

Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits

scientific article published on 12 August 2020

Gene-environment interactions differentially affect mouse strain behavioral parameters

scientific article published on 7 November 2006

Generation of mouse mutants as tools in dissecting the molecular clock

scientific article published in January 2012

Genetic and molecular analysis of the central and peripheral circadian clockwork of mice

scientific article published on January 2007

Genetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep

scientific article

Hippocampal NCAM180 transiently increases sialylation during the acquisition and consolidation of a passive avoidance response in the adult rat.

scientific article

Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits

scientific article

Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.

scientific article published on July 2000

Inducible Knockout of Mouse Zfhx3 Emphasizes Its Key Role in Setting the Pace and Amplitude of the Adult Circadian Clock

scientific article

Informatics for mutagenesis: the design of mutabase--a distributed data recording system for animal husbandry, mutagenesis, and phenotypic analysis

scientific article

KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility

scientific article

Learning-induced change in neural activity during acquisition and consolidation of a passive avoidance response in the rat.

scientific article published in May 1990

Loss of disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

scientific article published on 22 February 2019

Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light

scientific article (publication date: June 2016)

Meta-analysis of transcriptomic datasets identifies genes enriched in the mammalian circadian pacemaker.

scientific article

Mouse mutagenesis-systematic studies of mammalian gene function

scientific article

Mutagenesis and behavioral screening for altered circadian activity identifies the mouse mutant, Wheels

scientific article published on 01 December 1995

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

scientific article (publication date: July 2003)

Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse

scientific article published on 16 September 2002

Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans

scientific article

Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland

scientific journal article

N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders

scientific article published on November 2003

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

scientific article

Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2.

scientific article published on September 2007

Novel phenotypes identified by plasma biochemical screening in the mouse

scientific article published in October 2002

Overexpression of Fto leads to increased food intake and results in obesity

scientific article

Phenotyping first-generation genome editing mutants: a new standard?

scientific article published on 29 July 2017

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures

scientific article

Random mutagenesis screen for dominant behavioral mutations in mice

scientific article published on December 1997

Reaching and grasping phenotypes in the mouse (Mus musculus): a characterization of inbred strains and mutant lines

scientific article published on 15 June 2007

Reciprocal interactions between circadian clocks and aging

scientific article

Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours

scientific article

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

scientific article

Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort

scientific article

Running endurance abnormality in mdx mice

scientific article published on 01 February 2002

Screening for novel ENU-induced rhythm, entrainment and activity mutants.

scientific article published in August 2004

Sleep-like behavior and 24-h rhythm disruption in the Tc1 mouse model of Down syndrome

scientific article published on 16 February 2015

Soluble rat brain sialidase does not influence intracellular glycosylation of Golgi sialyltransferase or its constitutive glycoproteins

scientific article published on 01 June 1988

Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo

scientific article

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

scientific journal article

The Wheels mutation in the mouse causes vascular, hindbrain, and inner ear defects

scientific article

The Zfhx3-Mediated Axis Regulates Sleep and Interval Timing in Mice

scientific article

The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis

scientific article published on 19 December 2017

The guanine nucleotide exchange factor, Spata13, influences social behaviour and nocturnal activity

scientific article published on 24 April 2019

The role of mutagenesis in defining genes in behaviour

scientific article

Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouse

scientific article published on January 2004

Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders

scientific article published on 01 September 2004

Tuning the period of the mammalian circadian clock: additive and independent effects of CK1εTau and Fbxl3Afh mutations on mouse circadian behavior and molecular pacemaking.

scientific article published in January 2011

When clocks go bad: neurobehavioural consequences of disrupted circadian timing

scientific article