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List of works by Wei Chen

A human snoRNA with microRNA-like functions

scientific article

A novel X-linked recessive mental retardation syndrome comprising macrocephaly and ciliary dysfunction is allelic to oral-facial-digital type I syndrome

scientific article

A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation

scientific article published on September 2012

Altered histone acetylation is associated with age-dependent memory impairment in mice.

scientific article

An Integrated Understanding of the Molecular Mechanisms How Adipose Tissue Metabolism Affects Long-Term Body Weight Maintenance

scientific article published on 02 November 2018

Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation

scientific article published in July 2007

Breakpoint analysis of balanced chromosome rearrangements by next-generation paired-end sequencing

scientific article

CASB: a concanavalin A-based sample barcoding strategy for single-cell sequencing

scientific article published on 01 April 2021

CGHPRO -- a comprehensive data analysis tool for array CGH.

scientific article

CIGAR-seq, a CRISPR/Cas-based method for unbiased screening of novel mRNA modification regulators

scientific article published on 01 November 2020

Characterization of a 5.3 Mb deletion in 15q14 by comparative genomic hybridization using a whole genome "tiling path" BAC array in a girl with heart defect, cleft palate, and developmental delay

scientific article published in January 2007

Characterization of interstitial Xp duplications in two families by tiling path array CGH

Comparative analysis of transposable element vector systems in human cells

scientific article

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

scientific article

Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells

scientific article

Comprehensive survey of human brain microRNA by deep sequencing

scientific article

De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics

scientific article

Deciphering the porcine intestinal microRNA transcriptome

scientific article

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

scientific article

Discovering microRNAs from deep sequencing data using miRDeep

scientific article

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.

scientific article published in May 2012

Estimating accuracy of RNA-Seq and microarrays with proteomics

scientific article

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques

scientific article (publication date: April 2012)

Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus

scientific article published on 01 November 2019

Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.

scientific article

Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel

scientific article

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.

scientific article published on 08 December 2016

Global quantification of mammalian gene expression control

scientific article (publication date: 19 May 2011)

High frequency of submicroscopic genomic aberrations detected by tiling path array comparative genome hybridisation in patients with isolated congenital heart disease.

scientific article published on 19 August 2008

Homozygosity mapping in consanguineous families reveals extreme heterogeneity of non-syndromic autosomal recessive mental retardation and identifies 8 novel gene loci.

scientific article published on 21 November 2006

Hybridisation-based resequencing of 17 X-linked intellectual disability genes in 135 patients reveals novel mutations in ATRX, SLC6A8 and PQBP1.

scientific article

Impact of low copy repeats on the generation of balanced and unbalanced chromosomal aberrations in mental retardation

scientific article published in January 2006

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

scientific article published on 17 February 2020

Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells

scientific article

Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT

scientific article published on 13 June 2020

Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq

scientific article

Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression

scientific article published on 06 September 2009

Mapping translocation breakpoints by next-generation sequencing

scientific article published on 7 March 2008

MicroRNA expression and regulation in human, chimpanzee, and macaque brains

scientific article

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

scientific article

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates

scientific article

Mutation screening of brain-expressed X-chromosomal miRNA genes in 464 patients with nonsyndromic X-linked mental retardation

scientific article published on 20 December 2006

Next generation sequencing in a family with autosomal recessive Kahrizi syndrome (OMIM 612713) reveals a homozygous frameshift mutation in SRD5A3

scientific article

Pan-tissue analysis of allelic alternative polyadenylation suggests widespread functional regulation

scientific article published on 01 April 2020

Pervasive isoform-specific translational regulation via alternative transcription start sites in mammals.

scientific article published on 18 July 2016

Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells

scientific article (publication date: 26 October 2012)

Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains

scientific article

Retargeting transposon insertions by the adeno-associated virus Rep protein.

scientific article

ST3GAL3 mutations impair the development of higher cognitive functions.

scientific article

Sequence features associated with microRNA strand selection in humans and flies

scientific article

The IκB kinase complex is a regulator of mRNA stability

scientific article published on 22 November 2018

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

scientific article published on 04 December 2019

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

scientific article published on 10 October 2010

Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP.

scientific article published on 11 March 2010

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

scientific article

Widespread expression of piRNA-like molecules in somatic tissues

scientific article

Widespread splicing changes in human brain development and aging

scientific article published on January 2013

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

scientific article published on 12 September 2011

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