List of works - Mario L. Santiago

A chimeric human APOBEC3A protein with a three amino acid insertion confers differential HIV-1 and adeno-associated virus restriction.

scientific article

A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo

scientific article

APOBEC3A functions as a restriction factor of human papillomavirus

scientific article

Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue

scientific article

Amplification of a complete simian immunodeficiency virus genome from fecal RNA of a wild chimpanzee

scientific article

Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies

scientific article published on 11 July 2017

Cellular HIV-1 inhibition by truncated old world primate APOBEC3A proteins lacking a complete deaminase domain

scientific article published on 28 September 2014

Chimpanzee reservoirs of pandemic and nonpandemic HIV-1

scientific article

Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.

scientific article

Detection of bancroftian filariasis in human blood samples from Sorsogon province, the Philippines by polymerase chain reaction

scientific article published on August 2001

Differential virus restriction patterns of rhesus macaque and human APOBEC3A: implications for lentivirus evolution

scientific article published on 25 August 2011

Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages

scientific article

Effective activation alleviates the replication block of CCR5-tropic HIV-1 in chimpanzee CD4+ lymphocytes

scientific article published on 12 September 2009

Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains

scientific article published on 11 December 2013

Enhancement of HIV-1 infection and intestinal CD4+ T cell depletion ex vivo by gut microbes altered during chronic HIV-1 infection

scientific article published on 14 January 2016

Foci of endemic simian immunodeficiency virus infection in wild-living eastern chimpanzees (Pan troglodytes schweinfurthii).

scientific article

Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1.

scientific article published on 14 June 2017

Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.

scientific article

Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice

scientific article

Generation of infectious molecular clones of simian immunodeficiency virus from fecal consensus sequences of wild chimpanzees

scientific article published on 9 May 2007

High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition

scholarly article

Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-dependent Protein Degradation

scientific article published on 24 January 2018

Humoral immunity in the Friend retrovirus infection model

scientific article published on March 2013

IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.

scientific article published on 11 January 2013

Identification of the Schistosoma japonicum 22.6-kDa antigen as a major target of the human IgE response: similarity of IgE-binding epitopes to allergen peptides.

scientific article

Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif

scientific article

Immunoglobulin VH gene diversity and somatic hypermutation during SIV infection of rhesus macaques.

scientific article

Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection

scientific article

Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.

scientific article published on 24 March 2017

Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo

scientific article

Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo

scientific article published on 20 April 2016

Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms

scientific article published on 3 November 2015

Lentivirus restriction by diverse primate APOBEC3A proteins

scientific article published on 4 May 2013

Low abundance of colonic butyrate-producing bacteria in HIV infection is associated with microbial translocation and immune activation

scientific article

Microbial exposure alters HIV-1-induced mucosal CD4+ T cell death pathways Ex vivo.

scientific article published on 04 February 2014

Minimal variation in the Pfs28 ookinete antigen from Philippine field isolates of Plasmodium falciparum

scientific article published on July 1997

Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees

scientific article

Molecular identification of a 21.7 kDa schistosoma japonicum antigen as a target of the human IgE response

scientific article published on January 1999

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors

scientific article

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

scientific article

Nef-mediated TCR-CD3 and MHC-I down-modulation prevents CD4+ T cell depletion in natural SIV infection.

scientific article

Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response

scientific article

Noninvasive detection of Simian immunodeficiency virus infection in a wild-living L'Hoest's monkey (Cercopithecus Ihoesti).

scientific article published in December 2003

Noninvasive detection of new simian immunodeficiency virus lineages in captive sooty mangabeys: ability to amplify virion RNA from fecal samples correlates with viral load in plasma

scientific article

Origin of AIDS: contaminated polio vaccine theory refuted.

scientific article

Paramyosin is a major target of the human IgA response against Schistosoma japonicum

scientific article

Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor

scientific article

Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis

scientific article published on 16 October 2020

Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo

scientific article published on 7 October 2014

Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response

scientific article

Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection

scientific article published on 29 May 2013

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer

scientific article

SIVcpz in wild chimpanzees

scientific article

Simian Immunodeficiency Virus Infection in Free-Ranging Sooty Mangabeys (Cercocebus atys atys) from the Tai Forest, Cote d'Ivoire: Implications for the Origin of Epidemic Human Immunodeficiency Virus Type 2

Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2.

scientific article

Simian immunodeficiency virus infection in wild-caught chimpanzees from cameroon

scientific article published on January 2005

T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses

scientific article

Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.

scientific article

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.

scientific article published on 5 February 2016

The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.

scientific article

The origins of acquired immune deficiency syndrome viruses: where and when?

scientific article published in June 2001

The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria

scientific article

Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction

scientific article

Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIV(cpz) strains

scientific article

List of works by Mario L. Santiago

A chimeric human APOBEC3A protein with a three amino acid insertion confers differential HIV-1 and adeno-associated virus restriction.

A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo

APOBEC3A functions as a restriction factor of human papillomavirus

Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue

Amplification of a complete simian immunodeficiency virus genome from fecal RNA of a wild chimpanzee

Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies

Cellular HIV-1 inhibition by truncated old world primate APOBEC3A proteins lacking a complete deaminase domain

Chimpanzee reservoirs of pandemic and nonpandemic HIV-1

Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.

Detection of bancroftian filariasis in human blood samples from Sorsogon province, the Philippines by polymerase chain reaction

Differential virus restriction patterns of rhesus macaque and human APOBEC3A: implications for lentivirus evolution

Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages

Effective activation alleviates the replication block of CCR5-tropic HIV-1 in chimpanzee CD4+ lymphocytes

Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains

Enhancement of HIV-1 infection and intestinal CD4+ T cell depletion ex vivo by gut microbes altered during chronic HIV-1 infection

Foci of endemic simian immunodeficiency virus infection in wild-living eastern chimpanzees (Pan troglodytes schweinfurthii).

Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1.

Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.

Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice

Generation of infectious molecular clones of simian immunodeficiency virus from fecal consensus sequences of wild chimpanzees

High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition

Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-dependent Protein Degradation

Humoral immunity in the Friend retrovirus infection model

IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.

Identification of the Schistosoma japonicum 22.6-kDa antigen as a major target of the human IgE response: similarity of IgE-binding epitopes to allergen peptides.

Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif

Immunoglobulin VH gene diversity and somatic hypermutation during SIV infection of rhesus macaques.

Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection

Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.

Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo

Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo

Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms

Lentivirus restriction by diverse primate APOBEC3A proteins

Low abundance of colonic butyrate-producing bacteria in HIV infection is associated with microbial translocation and immune activation

Microbial exposure alters HIV-1-induced mucosal CD4+ T cell death pathways Ex vivo.

Minimal variation in the Pfs28 ookinete antigen from Philippine field isolates of Plasmodium falciparum

Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees

Molecular identification of a 21.7 kDa schistosoma japonicum antigen as a target of the human IgE response

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

Nef-mediated TCR-CD3 and MHC-I down-modulation prevents CD4+ T cell depletion in natural SIV infection.

Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response

Noninvasive detection of Simian immunodeficiency virus infection in a wild-living L'Hoest's monkey (Cercopithecus Ihoesti).

Noninvasive detection of new simian immunodeficiency virus lineages in captive sooty mangabeys: ability to amplify virion RNA from fecal samples correlates with viral load in plasma

Origin of AIDS: contaminated polio vaccine theory refuted.

Paramyosin is a major target of the human IgA response against Schistosoma japonicum

Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor

Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis

Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo

Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response

Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer

SIVcpz in wild chimpanzees

Simian Immunodeficiency Virus Infection in Free-Ranging Sooty Mangabeys (Cercocebus atys atys) from the Tai Forest, Cote d'Ivoire: Implications for the Origin of Epidemic Human Immunodeficiency Virus Type 2

Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2.

Simian immunodeficiency virus infection in wild-caught chimpanzees from cameroon

T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses

Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.

The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.

The origins of acquired immune deficiency syndrome viruses: where and when?

The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria

Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction

Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIV(cpz) strains