List of works - Genta Ito

Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in lewy body disease

scientific article published on 01 May 2007

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

scientific article published on 26 November 2007

Differential effects of familial parkinson mutations in LRRK2 revealed by a systematic analysis of autophosphorylation

scientific article published on 23 August 2013

Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor

scientific article published on 7 April 2015

Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease

scientific article published on November 2007

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

scientific article

Identification of the autophosphorylation sites of LRRK2.

scientific article

LRRK2 in Parkinson's disease and dementia with Lewy bodies

scientific article

Lack of correlation between the kinase activity of LRRK2 harboring kinase-modifying mutations and its phosphorylation at Ser910, 935, and Ser955.

scientific article

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

scientific article published on 06 March 2008

Lewy body pathology involves cutaneous nerves

scientific article published in October 2008

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

scientific article published on 29 July 2016

Phosphorylation of α-synuclein protein at Ser-129 reduces neuronal dysfunction by lowering its membrane binding property in Caenorhabditis elegans

scientific article published on 9 January 2012

Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form

scientific article published on February 2012

Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1.

scientific article published on 18 November 2005

Structural Characterization of LRRK2 Inhibitors

scientific article

List of works by Genta Ito

Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in lewy body disease

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

Differential effects of familial parkinson mutations in LRRK2 revealed by a systematic analysis of autophosphorylation

Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor

Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

Identification of the autophosphorylation sites of LRRK2.

LRRK2 in Parkinson's disease and dementia with Lewy bodies

Lack of correlation between the kinase activity of LRRK2 harboring kinase-modifying mutations and its phosphorylation at Ser910, 935, and Ser955.

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

Lewy body pathology involves cutaneous nerves

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

Phosphorylation of α-synuclein protein at Ser-129 reduces neuronal dysfunction by lowering its membrane binding property in Caenorhabditis elegans

Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form

Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1.

Structural Characterization of LRRK2 Inhibitors