List of works - Christoph Thomas

A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor

scientific article published on 13 March 2020

A new family of RhoGEFs activates the Rop molecular switch in plants

scientific article

Conformation space of a heterodimeric ABC exporter under turnover conditions

scientific article published on 17 July 2019

Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.

scientific article published on 09 January 2017

Design of a superior cytokine antagonist for topical ophthalmic use

scientific article

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

scientific article

MHC I chaperone complexes shaping immunity

scientific article published on 14 February 2019

Mechanistic Basis for Epitope Proofreading in the Peptide-Loading Complex

scientific article published on 28 September 2015

Multifaceted structures and mechanisms of ABC transport systems in health and disease.

scientific article published on 7 April 2018

Mutation analysis of Son of Sevenless in juvenile myelomonocytic leukemia

scientific article published on 22 February 2007

Proofreading of Peptide-MHC Complexes through Dynamic Multivalent Interactions

scientific article published on 8 February 2017

Purification and crystallization of the catalytic PRONE domain of RopGEF8 and its complex with Rop4 from Arabidopsis thaliana

scientific article published on 31 May 2006

Purification, crystallization and preliminary X-ray diffraction analysis of the plant Rho protein ROP5.

scientific article published on 30 November 2007

SOS1 is the second most common Noonan gene but plays no major role in cardio-facio-cutaneous syndrome

scientific article published on 23 June 2007

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

scientific article

Structural basis of Wnt recognition by Frizzled

scientific article

Structural evidence for a common intermediate in small G protein-GEF reactions

scientific article

Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex

scientific article published on January 2011

Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing

scientific article

Structure of the activating IL-1 receptor signaling complex

scientific article

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

scientific article

The role of the conserved switch II glutamate in guanine nucleotide exchange factor-mediated nucleotide exchange of GTP-binding proteins

scientific article

List of works by Christoph Thomas

A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor

A new family of RhoGEFs activates the Rop molecular switch in plants

Conformation space of a heterodimeric ABC exporter under turnover conditions

Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.

Design of a superior cytokine antagonist for topical ophthalmic use

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

MHC I chaperone complexes shaping immunity

Mechanistic Basis for Epitope Proofreading in the Peptide-Loading Complex

Multifaceted structures and mechanisms of ABC transport systems in health and disease.

Mutation analysis of Son of Sevenless in juvenile myelomonocytic leukemia

Proofreading of Peptide-MHC Complexes through Dynamic Multivalent Interactions

Purification and crystallization of the catalytic PRONE domain of RopGEF8 and its complex with Rop4 from Arabidopsis thaliana

Purification, crystallization and preliminary X-ray diffraction analysis of the plant Rho protein ROP5.

SOS1 is the second most common Noonan gene but plays no major role in cardio-facio-cutaneous syndrome

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

Structural basis of Wnt recognition by Frizzled

Structural evidence for a common intermediate in small G protein-GEF reactions

Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex

Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing

Structure of the activating IL-1 receptor signaling complex

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

The role of the conserved switch II glutamate in guanine nucleotide exchange factor-mediated nucleotide exchange of GTP-binding proteins