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List of works by Alexandre Alcais

A Recessive Major Gene Controls the Mitsuda Reaction in a Region Endemic for Leprosy

article

Age Is an Important Risk Factor for Onset and Sequelae of Reversal Reactions in Vietnamese Patients with Leprosy

scientific article published in 2007

Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies

scientific article published on 9 February 2017

Bacillus Calmette Guérin triggers the IL-12/IFN-γ axis by an IRAK-4- and NEMO-dependent, non-cognate interaction between monocytes, NK, and T lymphocytes

scientific article published on 01 November 2004

Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population

scientific article

Comparison of four sib-pair linkage methods for analyzing sibships with more than two affecteds: Interest of the binomial maximum likelihood approach

scientific article published on January 1, 1998

Evaluation of approaches to identify associated SNPs that explain the linkage evidence in nuclear families with affected siblings

scientific article

Evidence for a major gene controlling susceptibility to tegumentary leishmaniasis in a recently exposed Bolivian population

scientific article

Gains of glycosylation comprise an unexpectedly large group of pathogenic mutations

scientific article

Gains of glycosylation mutations

scientific article

Genetic dissection of immunity in leprosy

scientific article

Genetic predisposition to leprosy: A major gene reveals novel pathways of immunity to Mycobacterium leprae

scientific article

Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway

scientific article published on 20 April 2020

Genomewide Linkage Analysis of the Granulomatous Mitsuda Reaction Implicates Chromosomal Regions 2q35 and 17q21

article

Granulomatous reaction to intradermal injection of lepromin (Mitsuda reaction) is linked to the human NRAMP1 gene in Vietnamese leprosy sibships

scientific article

Herpes simplex virus encephalitis in human UNC-93B deficiency

scientific article

Human genetics of common mycobacterial infections

scientific article published on January 2003

IL-12Rβ1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey

scientific article (publication date: 13 April 2011)

Identification d’un nouveau gène de susceptibilité à la lèpre par clonage positionnel

article

IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients

scientific article (publication date: 13 December 2012)

Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases

scientific article

Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait

scientific article published on 30 December 2005

Incorporation of covariates in multipoint model-free linkage analysis of binary traits: how important are unaffecteds?

scientific article published on August 2001

Leprosy: a paradigm for the study of human genetic susceptibility to infectious diseases

scientific article published in May 2008

Longitudinal changes in the ductus venosus, cerebral transverse sinus and cardiotocogram in fetal growth restriction

scientific article published on 01 July 2000

Mycobacterial infections: PARK2 and PACRG associations in leprosy

scientific article published on April 2007

Mycolactone toxin induces an inflammatory response by targeting the IL-1β pathway: Mechanistic insight into Buruli ulcer pathophysiology

scientific article published on 18 December 2020

PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages

scientific article

Quantifying genomic imprinting in the presence of linkage

scientific article published in December 2006

Removing phenotypic distribution assumptions from tests of linkage disequilibrium for quantitative traits

scientific article

Reply to Zhang et al.: The differential role of LRRK2 variants in nested leprosy phenotypes

scientific article published on 28 April 2020

Segregation of HLA/TNF region is linked to leprosy clinical spectrum in families displaying mixed leprosy subtypes

article

Skin-specific antibodies neutralizing mycolactone toxin during the spontaneous healing of Mycobacterium ulcerans infection

scientific article published on 26 February 2020

Susceptibility to leprosy is associated with PARK2 and PACRG.

scientific article

Tuberculosis in children and adults: two distinct genetic diseases

scientific article published on December 2005

Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage

scientific article published on 31 May 2016