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List of works by Kasper Hoebe

A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice

scientific article

A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria

scientific journal article

ATF3 is a novel regulator of mouse neutrophil migration

scientific article

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

scientific article

An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance

scientific article

An ENU-induced splice site mutation of mouse Col1a1 causing recessive osteogenesis imperfecta and revealing a novel splicing rescue

scientific article published on 15 September 2017

Analysis of the MCMV resistome by ENU mutagenesis

scientific article published in May 2006

Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation

scholarly article by Zuping Zhou et al published June 2005 in European Journal of Immunology

C5a regulates NKT and NK cell functions in sepsis.

scientific article

CD36 is a sensor of diacylglycerides

scientific journal article

Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN.

scientific article published in November 2006

Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut

scientific article

Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery

scientific article

Critical role of transmethylation in TLR signaling and systemic lupus erythematosus

scientific article published on 5 March 2013

Cutting edge: Priming of NK cells by IL-18.

scientific article published on August 2008

Differential effects of pentoxifylline on the hepatic inflammatory response in porcine liver cell cultures. Increase in inducible nitric oxide synthase expression

scientific article published in May 2001

Dissecting innate immunity by germline mutagenesis

scientific article published on 18 January 2008

ENU mutagenesis in mice

scientific article published in January 2008

ENU-induced phenovariance in mice: inferences from 587 mutations

scientific article

Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway

scientific article (publication date: June 2006)

Endotoxin-induced liver damage in rats is minimized by beta 2-adrenoceptor stimulation

scientific article published on 16 February 2004

Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling

scientific article published in July 2005

Erratum: Corrigendum: Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

scientific article published in Nature

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

scientific article published in March 2005

Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules

scientific article published in September 2004

Forward genetic analysis of TLR-signaling pathways: an evaluation

scientific article published on 15 February 2008

Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses

scientific article published in June 2004

From phenomenon to phenotype and from phenotype to gene: forward genetics and the problem of sepsis

scientific article

Gab3 is required for IL-2- and IL-15-induced NK cell expansion and limits trophoblast invasion during pregnancy

scientific article published on 01 August 2019

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

scientific article

Genetic analysis of innate immunity

scientific article published on January 2006

Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses

scientific article

Genetic analysis of innate immunity: identification and function of the TIR adapter proteins

scientific article

Genetic dissection of Toll-like receptor signaling using ENU mutagenesis

scientific article published in January 2009

Gimap5-dependent inactivation of GSK3β is required for CD4+ T cell homeostasis and prevention of immune pathology

scientific article

Hepatic (dys-)function during inflammation

scientific article published on October 2003

Herpes simplex virus encephalitis in human UNC-93B deficiency

scientific article

How we detect microbes and respond to them: the Toll-like receptors and their transducers

scientific article

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

scientific journal article

Identification of a TLR4- and TRIF-dependent activation program of dendritic cells

scientific article published in February 2004

Immunology: Toll-like receptors and antibody responses

scientific article published on May 2006

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

scientific journal article

Jinx, an MCMV susceptibility phenotype caused by disruption ofUnc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

LPS, dsRNA and the interferon bridge to adaptive immune responses: Trif, Tram, and other TIR adaptor proteins

scientific article published on January 2004

Lampe1: an ENU-germline mutation causing spontaneous hepatosteatosis identified through targeted exon-enrichment and next-generation sequencing.

scientific article

Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice

scientific article

Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells

scientific article published on 21 November 2011

Lps2 and signal transduction in sepsis: at the intersection of host responses to bacteria and viruses

scientific article published on January 2003

Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening

scientific article published in January 2003

Myeloid-derived NF-κB negative regulation of PU.1 and c/EBP-β-driven pro-inflammatory cytokine production restrains LPS-induced shock

scientific article published on 8 December 2016

NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses

scientific article published on 30 April 2009

NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease

scientific article published on 30 March 2012

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria

scientific article published on 20 August 2006

New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B

scientific article published on 01 April 2008

Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways.

scientific article

PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development

scientific article published in June 2006

Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease

scientific article published on 22 March 2018

Pig MAP/ITIH4 and haptoglobin are interleukin-6-dependent acute-phase plasma proteins in porcine primary cultured hepatocytes

scientific article published on 01 March 2000

Respond to "No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice".

scientific article published in November 2013

STAT5 is critical to maintain effector CD8+ T cell responses.

scientific article

Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha

scientific article

Slp-76 is a critical determinant of NK-cell mediated recognition of missing-self targets

scientific article published on 22 May 2015

Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.

scientific article

TLR signaling pathways: opportunities for activation and blockade in pursuit of therapy

scientific article published on January 2006

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

scientific article published on May 2007

TRAF3: a new component of the TLR-signaling apparatus

The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung

scientific article published in November 2005

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

scientific article

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

scientific journal article

The interface between innate and adaptive immunity

scientific article published in October 2004

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

scientific article

Type I interferons regulate susceptibility to inflammation-induced preterm birth

scientific article published on 09 March 2017

Unraveling innate immunity using large scale N-ethyl-N-nitrosourea mutagenesis

scientific article

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

scientific article published on 16 November 2003

Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice

scientific article

Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway

scientific article published on 12 February 2007

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