List of works - Ben Croker

A Helicobacter pylori Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization

scientific article

A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis

scientific article published on 29 September 2008

ATP-sensitive potassium channels mediate survival during infection in mammals and insects

scientific article

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

scientific article published on 25 May 2015

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence

scientific article

BID-ding on necroptosis in MDS

scientific article published on 01 January 2019

Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies ⬇️

scientific article published on 5 August 2022

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

scientific article published on 16 April 2018

Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia

scientific article published on 28 July 2017

Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling

scientific article published on 05 June 2019

Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3.

scientific article published on 02 June 2015

ENU-induced phenovariance in mice: inferences from 587 mutations

scientific article

Fas regulates neutrophil lifespan during viral and bacterial infection

scientific article

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1

scientific article

Fight or flight: regulation of emergency hematopoiesis by pyroptosis and necroptosis

scientific article

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

scientific article

Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV).

scientific article

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

scientific article published on 20 October 2015

IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.

scientific article

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

scholarly article

Key Role of Suppressor of Cytokine Signaling 3 in Regulating gp130 Cytokine-Induced Signaling and Limiting Chondrocyte Responses During Murine Inflammatory Arthritis

article

Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors

scientific article published on 06 October 2020

Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors

scientific article published on 11 February 2021

Mutations in topoisomerase IIβ result in a B cell immunodeficiency

scientific article published on 13 August 2019

Myelopoiesis embraces its inner weakness.

scientific article published in August 2017

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells

scientific article

NLRP1a expression in Srebp-1a-deficient mice

scientific article published in March 2014

Neutrophil survival in the death zone

scientific article published on 01 January 2014

Neutrophils Require SHP1 To Regulate IL-1 Production and Prevent Inflammatory Skin Disease

scientific article published on 15 December 2010

Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation

scientific article published on February 2007

Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation

scientific article published on 09 December 2019

Pyroptotic death storms and cytopenia

scientific article published on 22 December 2013

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

scientific article published on 8 May 2014

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

scientific article

Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in TH 1 responses

article

Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production

scientific article

Resident and monocyte-derived dendritic cells become dominant IL-12 producers under different conditions and signaling pathways

scientific article published on 19 July 2010

SOCS regulation of the JAK/STAT signalling pathway

scientific article published on 30 July 2008

SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis

scientific article

SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis

scientific article published in February 2004

SOCS3 negatively regulates IL-6 signaling in vivo

scientific article

Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens

scientific article published in June 2018

Single-cell cloning of human T-cell lines reveals clonal variation in cell death responses to chemotherapeutics

scientific article published on 12 June 2019

Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation

scientific article published on 8 April 2008

Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination

scholarly article

The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils

scientific article published on 04 September 2018

The role of neutrophils during mild and severe influenza virus infections of mice

scientific article

Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene

scientific article

Towards a Four-Dimensional View of Neutrophils ⬇️

scientific article published on January 1, 2012

Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor

scientific article

β-glucan dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment

β-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment

scientific article published on 04 September 2019

List of works by Ben Croker

A Helicobacter pylori Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization

A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis

ATP-sensitive potassium channels mediate survival during infection in mammals and insects

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence

BID-ding on necroptosis in MDS

Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies ⬇️

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia

Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling

Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3.

ENU-induced phenovariance in mice: inferences from 587 mutations

Fas regulates neutrophil lifespan during viral and bacterial infection

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1

Fight or flight: regulation of emergency hematopoiesis by pyroptosis and necroptosis

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV).

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

Key Role of Suppressor of Cytokine Signaling 3 in Regulating gp130 Cytokine-Induced Signaling and Limiting Chondrocyte Responses During Murine Inflammatory Arthritis

Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors

Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors

Mutations in topoisomerase IIβ result in a B cell immunodeficiency

Myelopoiesis embraces its inner weakness.

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells

NLRP1a expression in Srebp-1a-deficient mice

Neutrophil survival in the death zone

Neutrophils Require SHP1 To Regulate IL-1 Production and Prevent Inflammatory Skin Disease

Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation

Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation

Pyroptotic death storms and cytopenia

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in TH 1 responses

Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production

Resident and monocyte-derived dendritic cells become dominant IL-12 producers under different conditions and signaling pathways

SOCS regulation of the JAK/STAT signalling pathway

SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis

SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis

SOCS3 negatively regulates IL-6 signaling in vivo

Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens

Single-cell cloning of human T-cell lines reveals clonal variation in cell death responses to chemotherapeutics

Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation

Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination

The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils

The role of neutrophils during mild and severe influenza virus infections of mice

Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene

Towards a Four-Dimensional View of Neutrophils ⬇️

Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor

β-glucan dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment

β-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment