List of works - Andreas Heger

11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet

scientific article

A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution

scientific article

A fully automatic evolutionary classification of protein folds: Dali Domain Dictionary version 3

scientific article

ADDA: a domain database with global coverage of the protein universe

scientific article

Accelerated evolution of PAK3- and PIM1-like kinase gene families in the zebra finch, Taeniopygia guttata

scientific article (publication date: August 2010)

Accurate detection of very sparse sequence motifs

scientific article published in January 2004

Accurate estimation of gene evolutionary rates using XRATE, with an application to transmembrane proteins.

scientific article

An analysis of the gene complement of a marsupial, Monodelphis domestica: evolution of lineage-specific genes and giant chromosomes

scientific article published on 10 May 2007

CGAT: a model for immersive personalized training in computational genomics

scientific article

CGAT: computational genomics analysis toolkit

scientific article

Comparative and demographic analysis of orang-utan genomes

scientific article

Corrigendum: Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes

scientific article published on 9 April 2015

Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling

scientific article published on 22 March 2016

Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

scientific article published on 26 February 2013

Estimating the significance of sequence order in protein secondary structure and prediction

scientific article published in November 2000

Evidence for conserved post-transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs

scientific article published on 15 November 2012

Evolution of genes and genomes on the Drosophila phylogeny

scientific article

Evolutionary rate analyses of orthologs and paralogs from 12 Drosophila genomes

scientific article

Exhaustive enumeration of protein domain families

scientific article published in May 2003

GAT: a simulation framework for testing the association of genomic intervals

scientific article published on 18 June 2013

Genome analysis of the platypus reveals unique signatures of evolution

scientific article

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

scientific article

Genome sequence, comparative analysis and haplotype structure of the domestic dog

scientific article

High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner

scientific article published on 23 August 2016

IRF5:RelA interaction targets inflammatory genes in macrophages

scientific article published on 21 August 2014

Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer

scientific article

Insights into hominid evolution from the gorilla genome sequence

scientific article

Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence

scientific article (publication date: 12 February 2013)

Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes

scientific article

Long noncoding RNAs in B-cell development and activation

scientific article published on 05 July 2016

Molecular evolution of genes in avian genomes

scientific article (publication date: 2010)

More for less in structural genomics

scientific article published on 01 January 2003

Mouse genomic variation and its effect on phenotypes and gene regulation

scientific article (publication date: 14 September 2011)

Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy

scientific article published on 14 August 2013

OPTIC: orthologous and paralogous transcripts in clades

scientific article published on 11 October 2007

PairsDB atlas of protein sequence space

scientific article published on 5 November 2007

Pfam: the protein families database

scientific article (publication date: 2014)

Picasso: generating a covering set of protein family profiles

scientific article published in March 2001

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia

scientific article

RSDB: representative protein sequence databases have high information content

scientific article published in May 2000

Rapid automatic detection and alignment of repeats in protein sequences

scientific article published in November 2000

Rapid bursts of androgen-binding protein (Abp) gene duplication occurred independently in diverse mammals

scientific article (publication date: 12 February 2008)

Sensitive pattern discovery with 'fuzzy' alignments of distantly related proteins

scientific article published on 01 January 2003

Sequencing depth and coverage: key considerations in genomic analyses

February 2014 scholarly article in Nature Reviews Genetics

Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment.

scientific article

The Pfam protein families database

scientific article (publication date: 2012)

The Pfam protein families database

scientific article (published 2010-01-01)

The genome of a songbird

scientific article

The genome of the green anole lizard and a comparative analysis with birds and mammals ⬇️

scientific article

The global trace graph, a novel paradigm for searching protein sequence databases

scientific article published on 6 September 2007

Towards a covering set of protein family profiles

scientific article

Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby.

scientific article published on 19 August 2011

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease

scientific article

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

scientific article published on 18 January 2017

Uncertainty in homology inferences: assessing and improving genomic sequence alignment

scientific article published on 11 December 2007

Variable strength of translational selection among 12 Drosophila species

scientific article published in November 2007

List of works by Andreas Heger

11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet

A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution

A fully automatic evolutionary classification of protein folds: Dali Domain Dictionary version 3

ADDA: a domain database with global coverage of the protein universe

Accelerated evolution of PAK3- and PIM1-like kinase gene families in the zebra finch, Taeniopygia guttata

Accurate detection of very sparse sequence motifs

Accurate estimation of gene evolutionary rates using XRATE, with an application to transmembrane proteins.

An analysis of the gene complement of a marsupial, Monodelphis domestica: evolution of lineage-specific genes and giant chromosomes

CGAT: a model for immersive personalized training in computational genomics

CGAT: computational genomics analysis toolkit

Comparative and demographic analysis of orang-utan genomes

Corrigendum: Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes

Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling

Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

Estimating the significance of sequence order in protein secondary structure and prediction

Evidence for conserved post-transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs

Evolution of genes and genomes on the Drosophila phylogeny

Evolutionary rate analyses of orthologs and paralogs from 12 Drosophila genomes

Exhaustive enumeration of protein domain families

GAT: a simulation framework for testing the association of genomic intervals

Genome analysis of the platypus reveals unique signatures of evolution

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

Genome sequence, comparative analysis and haplotype structure of the domestic dog

High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner

IRF5:RelA interaction targets inflammatory genes in macrophages

Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer

Insights into hominid evolution from the gorilla genome sequence

Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence

Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes

Long noncoding RNAs in B-cell development and activation

Molecular evolution of genes in avian genomes

More for less in structural genomics

Mouse genomic variation and its effect on phenotypes and gene regulation

Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy

OPTIC: orthologous and paralogous transcripts in clades

PairsDB atlas of protein sequence space

Pfam: the protein families database

Picasso: generating a covering set of protein family profiles

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia

RSDB: representative protein sequence databases have high information content

Rapid automatic detection and alignment of repeats in protein sequences

Rapid bursts of androgen-binding protein (Abp) gene duplication occurred independently in diverse mammals

Sensitive pattern discovery with 'fuzzy' alignments of distantly related proteins

Sequencing depth and coverage: key considerations in genomic analyses

Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment.

The Pfam protein families database

The Pfam protein families database

The genome of a songbird

The genome of the green anole lizard and a comparative analysis with birds and mammals ⬇️

The global trace graph, a novel paradigm for searching protein sequence databases

Towards a covering set of protein family profiles

Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby.

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

Uncertainty in homology inferences: assessing and improving genomic sequence alignment

Variable strength of translational selection among 12 Drosophila species