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List of works by Dhirendra K. Simanshu

A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer

scientific article

A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo

scientific article

Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels

scientific article

Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

scientific article published on 24 October 2019

Cloning, expression, purification and preliminary X-ray crystallographic studies of 2-methylisocitrate lyase from Salmonella typhimurium

scientific article published on 23 November 2002

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of propionate kinase (TdcD) from Salmonella typhimurium

scientific article

Conformational folding and stability of the HET-C2 glycolipid transfer protein fold: does a molten globule-like state regulate activity?

scientific article published on 19 May 2011

Crystal structure of Salmonella typhimurium 2-methylisocitrate lyase (PrpB) and its complex with pyruvate and Mg(2+)

scientific article

Crystal structures of ADP and AMPPNP-bound propionate kinase (TdcD) from Salmonella typhimurium: comparison with members of acetate and sugar kinase/heat shock cognate 70/actin superfamily

scientific article

Crystal structures of Salmonella typhimurium biodegradative threonine deaminase and its complex with CMP provide structural insights into ligand-induced oligomerization and enzyme activation

scientific article published on 17 October 2006

Crystal structures of Salmonella typhimurium propionate kinase and its complex with Ap4A: evidence for a novel Ap4A synthetic activity

scientific article

Crystallization and preliminary X-ray crystallographic analysis of biodegradative threonine deaminase (TdcB) from Salmonella typhimurium

scientific article published on 24 February 2006

Dicer recognizes the 5' end of RNA for efficient and accurate processing

scientific article

INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis

scientific article

KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis

scientific article published on 14 October 2019

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation

scientific article published on 19 February 2021

Mechanistic features of Salmonella typhimurium propionate kinase (TdcD): insights from kinetic and crystallographic studies

scientific article

Multimeric assembly and biochemical characterization of the Trax–translin endonuclease complex

scientific article

Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

scientific article

Phosphatidylserine Stimulates Ceramide 1-Phosphate (C1P) Intermembrane Transfer by C1P Transfer Proteins

scientific article published on 23 December 2016

Preliminary X-ray crystallographic analysis of 2-methylcitrate synthase from Salmonella typhimurium

scientific article

RAS Proteins and Their Regulators in Human Disease

scientific article published on June 2017

RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling

scientific article published on 11 May 2020

RIT1 oncoproteins escape LZTR1-mediated proteolysis

scientific article published on 01 March 2019

Sphingolipid transfer proteins defined by the GLTP-fold

scientific article

Structural Basis of mRNA Recognition and Cleavage by Toxin MazF and Its Regulation by Antitoxin MazE in Bacillus subtilis

scientific article

Structural Determination and Tryptophan Fluorescence of Heterokaryon Incompatibility C2 Protein (HET-C2), a Fungal Glycolipid Transfer Protein (GLTP), Provide Novel Insights into Glycolipid Specificity and Membrane Interaction by the GLTP Fold

scientific article

Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family

scientific article published on 11 September 2018

Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains

scientific article

Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase Aα

scientific article published on 3 May 2019

Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements

scientific article published in 2024

Structure of the putative mutarotase YeaD from Salmonella typhimurium: structural comparison with galactose mutarotases

scientific article

Systematic study on crystal-contact engineering of diphthine synthase: influence of mutations at crystal-packing regions on X-ray diffraction quality

scientific article

TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms

scientific article published on 15 May 2015

The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids

scientific article published on 16 November 2012

The small molecule BI-2852 induces a nonfunctional dimer of KRAS

scientific article published on 11 February 2020

Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane

scientific article published on 10 September 2020

Uridylation by TUT4 and TUT7 marks mRNA for degradation

scientific article

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