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List of works by Haitao Li

A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing

scientific article published on 01 May 2021

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

scientific article

ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons

scientific article

ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression

scientific article

Architecture of SAGA complex

scientific article published on 07 May 2019

Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells.

scientific article published on 28 August 2017

Beyond histone acetylation-writing and erasing histone acylations

scientific article published on 02 November 2018

Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interaction

article published in the Proceedings of the National Academy of Sciences of the United States of America

Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.

scientific article

Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia

scientific article published on 22 April 2022

Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis

scientific article published on 02 January 2014

Crystal structure of C-terminal desundecapeptide nitrite reductase from Achromobacter cycloclastes

scientific article published on 15 November 2005

Design, synthesis, structure-activity relationships study and X-ray crystallography of 3-substituted-indolin-2-one-5-carboxamide derivatives as PAK4 inhibitors

scientific article

Developing Spindlin1 small-molecule inhibitors by using protein microarrays

scientific article

Divergent lncRNAs Regulate Gene Expression and Lineage Differentiation in Pluripotent Cells

scientific article

Expanding RNA binding specificity and affinity of engineered PUF domains.

scientific article published on 27 February 2018

Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.

scientific article

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

scientific article

Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex

scientific article

Histone H3.3 phosphorylation amplifies stimulation-induced transcription

scientific article published on 22 July 2020

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3

scientific article published on 13 March 2019

Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.

scientific article published on 21 February 2018

Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells

scientific article published on 10 December 2018

Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP

scientific article published on 16 August 2019

JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis

scientific article

Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology

scientific article published on 14 August 2017

Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA

scientific article published on 12 February 2020

Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length

scientific article (publication date: 2016)

Molecular basis for hierarchical histone de-β-hydroxybutyrylation by SIRT3

scientific article published on 09 July 2019

Molecular basis for histidine N1 position-specific methylation by CARNMT1.

scientific article published on 20 February 2018

Molecular basis for histidine N3-specific methylation of actin H73 by SETD3

scientific article published on 21 January 2020

Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1

scientific article published on 29 September 2020

Molecular basis for histone N-terminal methylation by NRMT1

scientific journal article

Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1

scientific article

Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C.

scientific article published on 22 April 2016

Multivalent engagement of chromatin modifications by linked binding modules

scientific article (publication date: December 2007)

N6-methyladenine in DNA antagonizes SATB1 in early development

scientific article published on 15 July 2020

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

scientific article

Nucleolar localization signal and histone methylation reader function is required for SPIN1 to promote rRNA gene expression

scientific article published on 21 September 2018

PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression ⬇️

scientific article published on July 22, 2011

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

scientific article published on 22 February 2009

Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation

scientific article published on 13 November 2018

Preliminary crystallographic studies of two C-terminally truncated copper-containing nitrite reductases from Achromobacter cycloclastes: changed crystallizing behaviors caused by residue deletion

scientific article published on 01 November 2002

Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression

scientific article

Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".

scientific article published on 23 November 2015

Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions

scientific article

Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2.

scientific article published on 24 October 2016

Structural and biochemical characterization of DAXX-ATRX interaction.

scientific article published on 5 September 2017

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

scientific article

Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain

scientific article published in Nature Communications

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

scientific article

Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking

article

Systematic Profiling of Histone Readers in Arabidopsis thaliana

scientific article published on 28 January 2018

Targeting epigenetic regulators for cancer therapy

scientific article published on February 2014

The BAH domain of BAHD1 is a histone H3K27me3 reader

scientific article published on 5 February 2016

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape

scientific article published on 04 September 2019

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

scientific article

YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.

scientific article

Yng1 PHD Finger Binding to H3 Trimethylated at K4 Promotes NuA3 HAT Activity at K14 of H3 and Transcription at a Subset of Targeted ORFs

scientific article

ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression

scientific article

pH-profile crystal structure studies of C-terminal despentapeptide nitrite reductase from Achromobacter cycloclastes

scientific article published in March 2004

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