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List of works by Cameron Brennan

18F-Fluorocholine PET uptake correlates with pathologic evidence of recurrent tumor after stereotactic radiosurgery for brain metastases

scientific article published on 21 December 2019

18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers

scientific article

365 Epigenetic Profiling Reveals a Unique Histone Code in Chordoma

scientific article

A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle

scientific article

A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle

A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma

scientific article published on 6 November 2006

A phase 2 trial of stereotactic radiosurgery boost after surgical resection for brain metastases

scientific article published in January 2014

A principal components-based method for the detection of neuronal activity maps: application to optical imaging

scientific article published in April 2000

A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival

scientific article published on 24 June 2013

Acute inflammatory reactions to hemostatic materials mimicking post-operative intracranial abscess

Advanced imaging in brain tumor surgery

scientific article

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

scientific article

An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors

scientific article published on 15 June 2009

Array comparative genome hybridization for tumor classification and gene discovery in mouse models of malignant melanoma ⬇️

scientific article published on 01 September 2003

Assessment of the language laterality index in patients with brain tumor using functional MR imaging: effects of thresholding, task selection, and prior surgery

scientific article published on 09 January 2008

Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples

scientific article

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

scholarly article

CBMT-05. GENETIC AND EPIGENETIC MECHANISMS REGULATING SCD INHIBITOR SENSITIVITY IN GLIOBLASTOMA ⬇️

scholarly article

CHD4 regulates the DNA damage response and RAD51 expression in glioblastoma

scientific article published on 14 March 2019

CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer

scientific article

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

scientific article

Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma

scientific article published on 3 August 2012

Cell Lineage-Based Glioblastoma Stratification in Mice Reveals Functional Alignment with Patient Derived Models ⬇️

scholarly article

Cell Lineage-Based Stratification for Glioblastoma

scientific article published on 23 June 2020

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

scientific article published on 21 May 2007

Clinical Outcomes in Patients with Renal Cell Carcinoma Metastases to the Choroid Plexus

scientific article published on 03 April 2020

Clinical characterization of human metapneumovirus infection among patients with cancer

scientific article

Clinical outcomes of patients with limited brain metastases treated with hypofractionated (5×6Gy) conformal radiotherapy

scientific article published on 5 April 2017

Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression

scientific article published on April 2006

Common and Contrasting Genomic Profiles among the Major Human Lung Cancer Subtypes

Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types

scientific article published on November 2007

Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene

article

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

scientific article

Concordance between Functional Magnetic Resonance Imaging and Intraoperative Language Mapping

scientific article published on 01 January 1999

Concurrence of chromosome 6 chromothripsis and glioblastoma metastasis

scientific article published on 22 July 2016

Correction to: Sequencing and curation strategies for identifying candidate glioblastoma treatments

scientific article published on 02 August 2019

DNA amplification method tolerant to sample degradation

scientific article published on November 2004

Defining phenotypic and functional heterogeneity of glioblastoma stem cells by mass cytometry

scientific article published on 05 January 2021

Development of a gene expression-based prognostic signature for IDH wild-type glioblastoma

scientific article published on 08 September 2020

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

scientific article

Discordance between functional magnetic resonance imaging during silent speech tasks and intraoperative speech arrest

scientific article published on 01 August 2005

Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons

scientific article published on 12 August 2013

EGFR amplification and classical subtype are associated with a poor response to bevacizumab in recurrent glioblastoma

scientific article published on 24 January 2019

EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines

scientific article published on 22 August 2017

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.

scientific article published on October 2013

Emerging insights into the molecular and cellular basis of glioblastoma

scientific article published in April 2012

Emerging therapies for glioblastoma

scientific article

Erratum: Corrigendum: Passenger deletions generate therapeutic vulnerabilities in cancer

scientific article published in Nature

FGFR-TACC approaches the first turn in the race for targetable GBM mutations

scientific article

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

scientific article

Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions

scientific article published on 09 November 2020

Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.

scientific article published on 24 August 2017

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma.

scientific article

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas

scientific article published on 01 July 2019

Genomic Profiles of Glioma ⬇️

scientific article published on June 1, 2011

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

scientific article (publication date: May 2014)

Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO

scientific article

Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers

scientific article published on 7 November 2011

Glioblastoma stem-like cells give rise to tumour endothelium.

scientific article

Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations

scientific article

Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor

scientific article

Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo

scientific article published on February 2015

High-resolution characterization of the pancreatic adenocarcinoma genome

scholarly article

High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

article

High-resolution genomic profiles of human lung cancer

scientific article

High-resolution global profiling of genomic alterations with long oligonucleotide microarray

scientific article published on July 2004

Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

scientific article published on 22 August 2019

Hypofractionated stereotactic radiotherapy using intensity-modulated radiotherapy in patients with one or two brain metastases

scientific article published on 12 December 2006

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma.

scientific article published on 15 June 2017

Identification of DOK genes as lung tumor suppressors

scientific article

Incidence of Prolonged Systemic Steroid Treatment after Surgery for Acoustic Neuroma and Its Implications

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

scientific article

Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AML.

scientific article published in October 2017

Integrative genome comparison of primary and metastatic melanomas

scientific article

Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells

scientific article published on 23 May 2020

Intracranial metastasis in fibrolamellar hepatocellular carcinoma

scientific article published on 29 December 2017

Intraoperative Phosphorus-32 (P32) High-dose Rate (HDR) Dural Brachytherapy For Primary, Recurrent and Metastatic Intracranial Tumors

scholarly article published in July 2018

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

scientific article published on 8 February 2012

Isolated translocation of Wernicke's area to the right hemisphere in a 62-year-man with a temporo-parietal glioma.

scientific article published in January 2004

LY6K Promotes Glioblastoma Tumorigenicity via CAV-1-Mediated ERK1/2 Signaling Enhancement

scientific article published on 14 February 2020

Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases

scientific article published on 26 August 2015

Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas

scientific article published on December 2010

Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer

scientific article published on August 2010

Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis

scientific journal article

MEF promotes stemness in the pathogenesis of gliomas

scientific article published on December 2012

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

scientific article

MLTI-05. Adjuvant re-irradiation improves local control of surgically resected recurrent brain metastases

scientific article published in August 2021

MUTANT EGFR SUPPRESSION OF MICRORNA-9 INDUCES FOXP1 TO ENHANCE GLIOBLASTOMA TUMORIGENICITY.

scientific article published in July 2014

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies

scientific article

Magnetic resonance spectroscopy imaging in radiotherapy planning for recurrent gliomaa)

scientific article published on 01 May 2011

Malignant astrocytic glioma: genetics, biology, and paths to treatment

scientific article (publication date: November 2007)

Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities.

scientific article published on 17 November 2006

Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer

scientific article published on 10 February 2021

Metabolic Imaging of the Human Brain with Hyperpolarized C Pyruvate Demonstrates C Lactate Production in Brain Tumor Patients

scientific article published on 16 May 2018

Methods for DNA copy number derivations

Mig-6 controls EGFR trafficking and suppresses gliomagenesis

scientific article

Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics

scientific article published on 28 July 2020

Molecular characterization of the tumor microenvironment in breast cancer

scientific article

Molecular diversity of astrocytes with implications for neurological disorders

scholarly article

Molecular subclassification of diffuse gliomas: seeing order in the chaos

scientific article published on 28 March 2011

Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas

scientific article published on 23 April 2018

Multicenter Phase II Study of Temozolomide and Myeloablative Chemotherapy with Autologous Stem Cell Transplant for Newly Diagnosed Anaplastic Oligodendroglioma

scientific article published on 2 May 2017

Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer

scientific article published on 12 March 2019

Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence.

scientific article published on 27 November 2017

Neurosurgery for brain tumors: update on recent technical advances

scientific article

Nuclear cloning of embryonal carcinoma cells

scholarly article

Outcomes and prognostic factors in women with 1 to 3 breast cancer brain metastases treated with definitive stereotactic radiosurgery

scientific article published on 3 September 2014

PATH-49. GENOMIC ATTRIBUTES OF TUMOR EVOLUTION AND TREATMENT RESPONSE IN DIFFUSE GLIOMA

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

scientific article

PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas

scientific article

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

scientific article published on March 2009

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

scientific article published on February 2014

Passenger deletions generate therapeutic vulnerabilities in cancer

scientific article

Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells

scientific article

Phase II Multicenter, Open-Label Study of Oral ENMD-2076 for the Treatment of Patients with Advanced Fibrolamellar Carcinoma

scientific article published on 10 March 2020

Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma.

scientific article published on 8 August 2014

Presurgical evaluation of language using functional magnetic resonance imaging in brain tumor patients with previous surgery

scientific article

Prior malignancies in patients harboring glioblastoma: an institutional case-study of 2164 patients

scientific article published on 27 May 2017

Probing the AML Surfaceome for Chimeric Antigen Receptor (CAR) Targets ⬇️

scholarly article

Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis

scientific article

Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia

scientific article

Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma

scientific article published in January 2008

Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates

scientific article published on 29 November 2013

Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy

Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression

scientific article

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

scientific article

Reprogramming of a melanoma genome by nuclear transplantation

scientific article published on August 2004

SM-06DEXAMETHASONE USE DURING RADIOTHERAPY IN HIGH-GRADE GLIOMA: AN INSTITUTIONAL REVIEW

SURG-04. SALVAGE RESECTION OF RECURRENT PREVIOUSLY-IRRADIATED BRAIN METASTASES: CLINICAL AND RADIOGRAPHIC OUTCOMES

scientific article published in November 2020

Saccade preparation inhibits reorienting to recently attended locations

scientific article

Sequencing and curation strategies for identifying candidate glioblastoma treatments

scientific article published on 25 April 2019

Sleeping Beauty mouse models identify candidate genes involved in gliomagenesis

scientific article

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

scientific article

Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity

scientific article published on 16 January 2014

TM-15GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO.

scientific article

TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.).

scientific article published on 14 January 2013

Temporal Lobe Necrosis in Head and Neck Cancer Patients after Proton Therapy to the Skull Base

scientific article published on 28 May 2020

Thalamic Glioblastoma: Clinical Presentation, Management Strategies, and Outcomes.

scientific article published on 21 July 2017

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

scientific article

The Somatic Genomic Landscape of Glioblastoma

article

The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation

scientific article

The role of radiotherapy following gross-total resection of atypical meningiomas

scientific article published on 24 August 2012

The somatic genomic landscape of glioblastoma

scientific article

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

scientific journal article

Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid

scientific article published on 23 January 2019

Transcriptional diversity of long-term glioblastoma survivors.

scientific article

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

scientific article

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

scientific article published on 14 January 2019

Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class

scientific article published on 17 July 2013

Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model

scientific article published on 12 September 2019

Ultrasmall dual-modality silica nanoparticle drug conjugates: Design, synthesis, and characterization

scientific article published on 9 October 2015

Use of the Omental Free Flap for Treatment of Chronic Anterior Skull Base Infections

scientific article published on 11 August 2020

microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. ⬇️

scientific article

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

scientific article

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