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List of works by Reuven Agami

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

scientific article

3'UTR-mediated gene silencing of the Mixed Lineage Leukemia (MLL) gene

scientific article published in 2011

A PASport to cellular proliferation

scientific article

A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility

scientific article

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis

scientific article published on 29 January 2021

A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d

scientific article

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity

scientific article

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

scientific article

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

scientific article

A p53-bound enhancer region controls a long intergenic noncoding RNA required for p53 stress response.

scientific article published on 18 January 2016

A system for stable expression of short interfering RNAs in mammalian cells

scientific article (publication date: 19 April 2002)

A versatile microsatellite instability reporter system in human cells

scientific article published on 16 July 2013

AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation

scientific article

All roads lead to IKKepsilon

scientific article

Altered microRNA expression associated with chromosomal changes contributes to cervical carcinogenesis

scientific article

Alternative Cleavage and Polyadenylation during Colorectal Cancer Development

article

Alternative cleavage and polyadenylation: extent, regulation and function

scientific article

Applying CRISPR-Cas9 tools to identify and characterize transcriptional enhancers.

scientific article published on 6 July 2016

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

scientific article published on 25 July 2016

BRD7 is a candidate tumour suppressor gene required for p53 function

scientific article

CDK-dependent stabilization of Cdc6: linking growth and stress signals to activation of DNA replication

scientific article published on 22 December 2005

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells

scientific article published on 23 August 2018

Characterization of noncoding regulatory DNA in the human genome

scientific article published on 01 August 2017

Classifying microRNAs in cancer: the good, the bad and the ugly

scientific article published on 22 November 2006

Convergence of mitogenic and DNA damage signaling in the G1 phase of the cell cycle

scientific article

Correction: 3′UTR-Mediated Gene Silencing of the Mixed Lineage Leukemia (MLL) Gene.

scientific article published on 10 November 2011

Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia

scientific article

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

article

Diverse ways to control p27Kip1 function: miRNAs come into play

scientific article

E2F mediates enhanced alternative polyadenylation in proliferation

scientific article

Enhancer-associated RNAs as therapeutic targets

scientific article published on 29 March 2015

Exogenous treatment with indole-3-acetic acid and salicylic acid alleviates cadmium toxicity in wheat seedlings

scientific article published on 17 May 2013

Exposure to arginine analog canavanine induces aberrant mitochondrial translation products, mitoribosome stalling, and instability of the mitochondrial proteome

scientific article

FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming

scientific article published on 28 February 2018

Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence

Functional analysis of cis-acting DNA elements required for expression of the SL RNA gene in the parasitic protozoan Leishmania amazonensis

scientific article published on June 1994

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

scientific article published on 11 January 2016

GRO-seq, A Tool for Identification of Transcripts Regulating Gene Expression.

scientific article published on January 2017

Gene regulation and tumor suppression by the bromodomain-containing protein BRD7.

scientific article

Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart

scientific article published on 15 December 2015

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.

scientific article

HBV integrants of hepatocellular carcinoma cell lines contain an active enhancer

scientific article

Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability

scientific article

Identification of lethal microRNAs specific for head and neck cancer

scientific article

Immense promises for tiny molecules: uncovering miRNA functions

scientific article published on July 2006

Immunofluorescence-based screening identifies germ cell associated microRNA 302 as an antagonist to p63 expression

scientific article published on 27 May 2009

Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein

scientific article

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

scientific article (publication date: 24 June 1999)

Interplay between microRNAs and RNA-binding proteins determines developmental processes

scientific article

Knockdown stands up

scientific article (publication date: 2003)

Leishmania mexicana amazonensis: Effect of Heat Shock on the Spliced Leader RNA and Its Ribonucleoprotein Particle SL RNP

article published in 1993

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

scientific article published on 22 February 2018

Lncing protein translation to metastasis

scientific article published on 24 September 2013

Long non-coding RNAs in metastasis.

scientific article published on 11 December 2017

MIR181A regulates starvation- and rapamycin-induced autophagy through targeting of ATG5.

scientific article published on 15 January 2013

Major role for mRNA stability in shaping the kinetics of gene induction

scientific article

Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer.

scientific article

Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis

scientific article published on 16 January 2013

MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression

scientific article

MicroRNA hsa-miR-135b regulates mineralization in osteogenic differentiation of human unrestricted somatic stem cells

scientific article published on June 2010

MicroRNA regulation by RNA-binding proteins and its implications for cancer

scientific article published on 05 August 2011

More or less - the same? mRNA fluctuations are balanced during translation

scientific article published on 22 October 2019

Myc coordinates transcription and translation to enhance transformation and suppress invasiveness

scientific article

Noncoding RNAs and Cancer

scientific article published on 01 March 2013

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair

scientific article published on 14 December 2017

Nucleotide sequence of the spliced leader RNA gene from Leishmania mexicana amazonensis

scientific article

Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer.

scientific article published on May 2013

Proteomic patterns associated with response to breast cancer neoadjuvant treatment

scientific article published on 01 September 2020

Queuing up the ribosome: nutrition and the microbiome control protein synthesis

scholarly article by Itamar Kozlovski published in September 2018

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA

scientific article

RNAi and related mechanisms and their potential use for therapy

scientific article

Ras interference as cancer therapy

scientific article

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

scientific article

Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer

scientific article

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

scientific article

Removal of AU bias from microarray mRNA expression data enhances computational identification of active microRNAs

scientific article

Ribosome profiling reveals features of normal and disease-associated mitochondrial translation

scientific article published on January 2013

SLC1A3 contributes to L-asparaginase resistance in solid tumors

scientific article published on 16 September 2019

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

scientific article published on 25 October 2011

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

scientific article

Stable suppression of tumorigenicity by virus-mediated RNA interference

scientific article published in September 2002

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

scientific article

TGFβ1-induced leucine limitation uncovered by differential ribosome codon reading.

scientific article published on 8 March 2017

Telomerase-independent regulation of ATR by human telomerase RNA.

scientific article published on 10 November 2006

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

scientific article

The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs.

scientific article

The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFXI, a protein that binds the enhancers of several viruses and cell-cycle regulated genes

scientific article

The methylated way to translation.

scientific article

The miRNA-192/194 cluster regulates the Period gene family and the circadian clock

scientific article

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

scientific article

The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.

scientific article

The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities

scientific article

The tumor-suppressive functions of the human INK4A locus

scientific article published on 01 October 2003

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels

scientific article published on 04 April 2020

Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.

scientific article

Transcription initiation determines its end.

scientific article published in January 2015

Transformation Locked in a Loop

article published in 2009

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

scientific article published on 09 March 2022

Tumorigenicity of the miR-17-92 cluster distilled

scientific article

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.

scientific article published on 15 February 2016

Unraveling human tumor suppressor pathways: a tale of the INK4A locus

scientific article published on 15 May 2004

Using mitoribosomal profiling to investigate human mitochondrial translation.

scientific article published on 11 December 2017

eRNAs are required for p53-dependent enhancer activity and gene transcription

scientific article

eRNAs reach the heart of transcription

scientific article published on 23 July 2013

miR-148 targets human DNMT3b protein coding region

scientific article

miR-155 drives telomere fragility in human breast cancer by targeting TRF1.

scientific article published on 29 May 2014

miR-21 and miR-214 are consistently modulated during renal injury in rodent models

scientific journal article

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1.

scientific article published on February 2012

miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate

scientific article

microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network

scientific article published on August 2016

microRNAs, RNA binding proteins and cancer

scientific article published on April 2010

p140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues

scientific article published on March 1996

p53 induces transcriptional and translational programs to suppress cell proliferation and growth.

scientific article published on 17 April 2013

p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation

scientific article

shRNA-mediated RNA interference as a tool for genetic synthetic lethality screening in mouse embryo fibroblasts

scientific article published in January 2005

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