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List of works by Haruhiko Koseki

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

scientific article published in April 2018

A Lysosomal Protein Negatively Regulates Surface T Cell Antigen Receptor Expression by Promoting CD3ζ-Chain Degradation

article by Rika Ouchida et al published July 2008 in Immunity

A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins

scientific article

A new Pax gene, Pax-9, maps to mouse chromosome 12.

scientific article

A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development.

scientific article

A novel gene essential for the development of single positive thymocytes

scientific article published on 20 July 2009

A novel pathogenesis of megacolon in Ncx/Hox11L.1 deficient mice ⬇️

scientific article published on August 15, 1997

A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1

scientific journal article

A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin

scientific article published in October 2007

A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell

scientific article

A promoter-level mammalian expression atlas

scientific article

Aberrant quality control in the endoplasmic reticulum impairs the biosynthesis of pulmonary surfactant in mice expressing mutant BiP.

scientific article published on 20 April 2007

Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.

scientific article published in December 2004

Abnormal blood vessel development in mice lacking presenilin-1.

scientific article published in June 2003

Accelerated acquisition of permeability barrier function in the skin of presenilin-1-deficient embryos

scientific article published on 13 September 2006

Accumulation of p27 KIP1 is associated with BMP2-induced growth arrest and neuronal differentiation of human neuroblastoma-derived cell lines

scientific article published on 01 July 2003

Activation of Endogenous Retroviruses in Dnmt1(-/-) ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA.

scientific article

Altered quality control in the endoplasmic reticulum causes cortical dysplasia in knock-in mice expressing a mutant BiP.

scientific article

An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells

scientific article published in November 2017

An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity.

scientific article published on 31 July 2013

An essential role for REV3 in mammalian cell survival: absence of REV3 induces p53-independent embryonic death

scientific article published on 01 May 2002

Angiopoietin-related growth factor antagonizes obesity and insulin resistance

scientific article

Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing

scientific article

Autoreactive T-cell clones which suppress cytotoxic T cell responses

scientific article

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome

scientific article published on 18 September 2018

Bmi1 confers resistance to oxidative stress on hematopoietic stem cells

scientific article

Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing

scientific article published on 29 December 2006

Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma

scientific article

Bmi1 regulates cell fate via tumor suppressor WWOX repression in small-cell lung cancer cells

scientific article published on 15 March 2011

Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I

scientific journal article

Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.

scientific article

Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

scientific article

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis

scientific article

CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration

scientific article

CCN3 protein participates in bone regeneration as an inhibitory factor

scientific journal article

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

scientific article

CD69-null mice protected from arthritis induced with anti-type II collagen antibodies.

scientific article

CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats

scientific article published on 20 October 2020

CFC1 is a cancer stemness-regulating factor in neuroblastoma.

scientific article published on 13 June 2017

CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.

scientific article

CRTAM Confers Late-Stage Activation of CD8+ T Cells to Regulate Retention within Lymph Node

Cell cycle-dependent turnover of 5-hydroxymethyl cytosine in mouse embryonic stem cells

scientific article

Cell-autonomous involvement of Mab21l1 is essential for lens placode development

scientific journal article

Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1

scientific article

Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method

scientific article (publication date: 30 April 2002)

Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif

scientific article

Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model

scientific article published on 13 February 2019

Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes

scientific article published on 05 April 2020

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

scientific article (publication date: 19 December 2013)

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders

scientific article published on 11 November 2013

Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells

scientific article

Control of developmental regulators by Polycomb in human embryonic stem cells

scientific article (publication date: 21 April 2006)

Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program

scientific article published on 02 December 2016

Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor

scientific article

Correction

Correction: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes

scientific article published on 25 April 2017

Correction: The Zinc Transporter SLC39A13/ZIP13 Is Required for Connective Tissue Development; Its Involvement in BMP/TGF-β Signaling Pathways.

scientific article published on 13 November 2008

DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes

scientific article

De novo DNA methylation drives 5hmC accumulation in mouse zygotes

scientific article published on 11 January 2016

Deep phenotyping of myalgic encephalomyelitis/chronic fatigue syndrome in Japanese population

scientific article published on 16 November 2020

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance

scientific article

Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia

scientific article published in May 2000

Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression

scientific article

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.

scientific article

Depletion of Sf3b1 impairs proliferative capacity of hematopoietic stem cells but is not sufficient to induce myelodysplasia

scientific article published on 15 April 2014

Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines

scientific article

Development of Valpha4+ NK T cells in the early stages of embryogenesis

scientific article published on June 1996

Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice

scientific article

Disruption of the Bcl6 Gene Results in an Impaired Germinal Center Formation ⬇️

scientific article published on August 4, 1997

Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase

scientific article published on 22 July 2003

Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8

scientific journal article

Divergence of CpG island promoters: a consequence or cause of evolution?

scientific article published on 01 August 2010

Dominant expression of a distinctive V14+ T-cell antigen receptor alpha chain in mice

scientific article published on September 1991

Double-step and inverse polymerase chain reaction for sensitive detection and cloning of T cell receptor variable region sequences

scientific article

Dual Functions of the RFTS Domain of Dnmt1 in Replication-Coupled DNA Methylation and in Protection of the Genome from Aberrant Methylation.

scientific article published on 18 September 2015

Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice

scientific article published on 7 April 2006

EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice

scientific article published on 10 July 2017

ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency

scientific article published on June 2010

Effects of BMP7 Produced by Group 2 Innate Lymphoid Cells on Adipogenesis

scientific article published on 09 March 2020

Efficient Regeneration of Human Vα24+ Invariant Natural Killer T Cells and Their Anti-Tumor Activity In Vivo.

scientific article published on 16 July 2016

Elbow knee synostosis (Eks): a new mutation on mouse Chromosome 14

scientific article published on 01 July 2002

Embracing change to remain the same: conservation of polycomb functions despite divergence of binding motifs among species

scientific article published on 13 March 2013

Enhanced Th2 cell differentiation and allergen-induced airway inflammation in Zfp35-deficient mice

scientific journal article

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

scientific article published on 01 December 2004

Epigenetic memory meets G2/M: to remember or to forget?

scientific article published in January 2011

Epigenetics in development: decorating the genome to show or hide?

scientific article published on 01 August 2010

Erratum: Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

scientific article published in Nature

Essential requirement of an invariant V alpha 14 T cell antigen receptor expression in the development of natural killer T cells

scientific article published on October 1996

Estrogen, insulin, and dietary signals cooperatively regulate longevity signals to enhance resistance to oxidative stress in mice

scientific article published on 15 February 2005

Expression of avian Pax1 and Pax9 is intrinsically regulated in the pharyngeal endoderm, but depends on environmental influences in the paraxial mesoderm.

scientific article published in September 1996

Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch

scientific article published on 01 March 2003

Expression of the Dan gene during chicken embryonic development ⬇️

scientific article published on December 1, 2001

Extrathymic development of V alpha 14-positive T cells

scientific article published on May 1993

Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia

scientific article published on 7 June 2012

Ezh2 is required for neural crest-derived cartilage and bone formation.

scientific article

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation

scientific article published on 23 June 2014

FANTOM5 CAGE profiles of human and mouse samples

scientific article published on 29 August 2017

FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment.

scientific article published on 29 May 2018

FBXL19 recruits CDK-Mediator to CpG islands of developmental genes to prime them for activation during lineage commitment

article

FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

scientific article published on 15 February 2009

Fc receptor beta subunit is required for full activation of mast cells through Fc receptor engagement

scientific article published on February 1999

Fine genetic mapping of the proximal part of mouse chromosome 2 excludes Pax-8 as a candidate gene for Danforth's short tail (Sd)

scientific article published on 01 January 1993

Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine

scientific article published on 09 February 2006

Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs.

scientific article published on 17 June 2016

Functional annotation of human long noncoding RNAs via molecular phenotyping

scientific article published on 27 July 2020

Gab2, via PI-3K, regulates ARF1 in FcεRI-mediated granule translocation and mast cell degranulation

scientific article published on 8 June 2011

Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs

scientific article

Generation of Melanoma Antigen Specific T Cells From Human Ips Cells Using a Feeder Free System

scientific article

Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire

scientific article

Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System.

scientific article published in March 2018

Generation of cloned mice by direct nuclear transfer from natural killer T cells

scientific article published in June 2005

Generation of functional NKT cells in vitro from embryonic stem cells bearing rearranged invariant Valpha14-Jalpha18 TCRalpha gene

scientific article published on 06 November 2009

Generation of induced pluripotent stem cell-derived mice by reprogramming of a mature NKT cell

scientific article published on 22 May 2014

Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation

scientific article

Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells

scientific article published on 22 February 2011

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

scientific article published in October 2008

Growth retardation and skin abnormalities of the Recql4-deficient mouse

scientific article published on 29 July 2003

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.

scientific article

H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

scientific article

HP1γ links histone methylation marks to meiotic synapsis in mice

scientific article published on 01 October 2011

Heat shock-induced homeotic transformations of the axial skeleton and associated shifts of Hox gene expression domains in mouse embryos

scientific article published in November 1997

Hemimethylation: DNA's lasting odd couple

scientific article published on 01 March 2018

Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity

scientific article

Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development

scientific article published on 18 December 2014

Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells

scientific article published on 26 February 2014

Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development

scientific article published on 13 June 2019

Homogenous junctional sequence of the V14+ T-cell antigen receptor alpha chain expanded in unprimed mice

scientific article

Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice

scientific article published on 01 April 2019

Human cell clones, RSa and UVr-1, differing in their capability for UV-induced virus reactivation and phenotypic mutation

scientific article

Human gain-of-function STAT1 mutation disturbs IL-17 immunity in mice

scientific article published on 01 April 2020

Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis

scientific article

Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2.

scientific article

Identification of loss-of-function mutations of SLC35D1 in patients with Schneckenbecken dysplasia, but not with other severe spondylodysplastic dysplasias group diseases

scientific article

Identification of the Coiled-Coil Domain as an Essential Methyl-CpG-Binding Domain Protein 3 Element for Preserving Lineage Commitment Potential of Embryonic Stem Cells

scientific article published on 15 July 2018

Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family

scientific journal article

Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice

scientific journal article

In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses

scientific article

Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion.

scientific article

Induced pluripotency as a potential path towards iNKT cell-mediated cancer immunotherapy

scientific article

Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Valpha14 natural killer T cells

scientific article published on September 1999

Insulin resistance and increased pancreatic beta-cell proliferation in mice expressing a mutant insulin receptor (P1195L)

scientific article published on 01 September 2006

Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies

scientific article

Involvement of decidual Valpha14 NKT cells in abortion

scientific article

Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice

scientific article (publication date: September 2002)

Irxl1 mutant mice show reduced tendon differentiation and no patterning defects in musculoskeletal system development ⬇️

scientific article published on December 22, 2010

Is there a role for endogenous retroviruses to mediate long-term adaptive phenotypic response upon environmental inputs?

scientific article (publication date: 5 January 2013)

KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.

scientific article

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity

scientific article published on 01 September 2019

KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis

scientific article published on 01 September 2019

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands.

scientific article

Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice

scientific article published on 12 November 2019

Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes

scientific article published on 20 February 2012

Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells

scientific article

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells

scientific article

MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation

scientific article (publication date: August 2002)

Maintenance of undifferentiated state and self-renewal of embryonic neural stem cells by Polycomb protein Ring1B.

scientific article published in July 2009

Mammal-specific H2A variant, H2ABbd, is involved in apoptotic induction via activation of NF-κB signaling pathway

scientific article

Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes

scientific journal article

Mammalian Polycomb complexes are required for Peyer's patch development by regulating lymphoid cell proliferation

scientific article published on 25 May 2006

Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes

scientific article published in July 2014

Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes

scientific article published in July 2014

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

scientific journal article

Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1

scientific journal article

Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes

scientific journal article

Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis

scientific article published on 25 July 2019

Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation

scientific article published on 25 January 2012

Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs

scientific journal article

Mesenchymal transcription factor Fkh6 is essential for the development and differentiation of parietal cells

scientific article

Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation ⬇️

scientific article published on July 15, 1997

Molecular cloning, genetic mapping, and expression of the mouse Sf3b1 (SAP155) gene for the U2 snRNP component of spliceosome

scientific article

Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status

scientific article published on 01 March 2020

Monoclonal antibody against murine T cell receptor V alpha 14 cross-reacts with human CD3 epsilon and detects disulfide-linked dimeric form

scientific article published on 01 October 1991

Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis

scientific journal article

Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1

scientific article (publication date: May 2002)

Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells

scientific article published on July 2010

Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells

scientific article

No Winter Lasts Forever: Polycomb Complexes Convert Epigenetic Memory of Cold into Flowering

scientific article published in September 2017

Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells

scientific article

Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development

scientific journal article

Novel regulation of MHC class II function in B cells

scientific journal article

Nuclear inhibitor of protein phosphatase-1 (NIPP1) directs protein phosphatase-1 (PP1) to dephosphorylate the U2 small nuclear ribonucleoprotein particle (snRNP) component, spliceosome-associated protein 155 (Sap155)

scientific article

Nuclear transcriptome profiling of induced pluripotent stem cells and embryonic stem cells identify non-coding loci resistant to reprogramming

scientific article

Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human

scientific journal article

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

scientific article published on 5 May 2010

Overlapping Roles for Homeodomain-Interacting Protein Kinases Hipk1 and Hipk2 in the Mediation of Cell Growth in Response to Morphogenetic and Genotoxic Signals

Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals

scientific article

PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation

scientific article published on June 2017

PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.

scientific article published on 17 March 2017

PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes

scientific article published on 24 January 2019

PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos

scientific journal article

PRC1-mediated epigenetic programming is required to generate the ovarian reserve

scientific article published in 2022

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

scientific article published on 11 September 2019

Pax genes and organogenesis.

scientific article

Pax-1, a regulator of sclerotome development is induced by notochord and floor plate signals in avian embryos.

scientific article published in April 1995

Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression

scientific article published on 02 August 2019

Physical interaction between MPP8 and PRC1 complex and its implication for regulation of spermatogenesis

scientific article

Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.

scientific article published on 16 November 2017

Pillars article: homogenous junctional sequence of the V14+ T-cell antigen receptor α chain expanded in unprimed mice. Proc. Natl. Acad. Sci. U.S.A. 1990. 87: 5248-5252

scholarly article

Polycomb complexes regulate cellular senescence by repression of ARF in cooperation with E2F3

scientific article published on 01 December 2007

Polycomb directs timely activation of germline genes in spermatogenesis

scientific article published on 18 September 2017

Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung

scientific article published on 17 March 2010

Polycomb group molecule PHC3 regulates polycomb complex composition and prognosis of osteosarcoma.

scientific article

Polycomb group protein Ezh2 regulates hepatic progenitor cell proliferation and differentiation in murine embryonic liver

scientific article

Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity

scientific article

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

scientific journal article

Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis

scientific article published on 14 April 2022

Polycomb in Transcriptional Phase Transition of Developmental Genes

scientific article published on 07 December 2015

Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition

scientific article published in September 2009

Polycomb potentiates meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer

scientific article published on 26 December 2013

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

scientific article published on 14 April 2014

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

scientific article published on 31 August 2015

Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells

scientific article

Positive selection of invariant V alpha 14+ T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells

scientific article

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries

scientific article published in April 2004

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libra

scientific article

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated librar

scientific article

Presenilin-1 controls the growth and differentiation of endothelial progenitor cells through its beta-catenin-binding region

scientific article published on 22 December 2005

Production of monoclonal antibodies against quail Pax-1

scientific article published on 01 February 1996

Protective role of macrophages in noninflammatory lung injury caused by selective ablation of alveolar epithelial type II Cells

scientific article published on 01 April 2007

Publisher Correction: Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity

scientific article published on 21 September 2020

RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression

scientific article published on 16 December 2015

RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells.

scientific article published on 23 January 2012

Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants

scientific article published on 31 October 2003

Recruitment of Dnmt1 roles of the SRA protein Np95 (Uhrf1) and other factors

scientific article published on January 2011

Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing

scientific article

Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma

scientific article published in March 2004

Reduction of SNAP25 in acid secretion defect of Foxl1-/- gastric parietal cells

scientific article published in July 2004

Regeneration of CD8αβ T Cells from T-cell-Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity

scientific article published on 21 November 2016

Regeneration of human tumor antigen-specific T cells from iPSCs derived from mature CD8(+) T cells

scientific article

Regulation of Fetal Genes by Transitions among RNA-Binding Proteins during Liver Development

scientific article published on 07 December 2020

Regulation of Th2 cell development by Polycomb group gene bmi-1 through the stabilization of GATA3.

scientific article

Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing

scientific article published on 02 December 2021

Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.

scientific article published on 11 July 2013

Repressor of GATA regulates TH2-driven allergic airway inflammation and airway hyperresponsiveness

scientific article published on 11 July 2008

Reproductive isolation in hybrid mice due to spermatogenesis defects at three meiotic stages

scientific article

Requirement for Mab21l2 during development of murine retina and ventral body wall

scientific journal article

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

scientific article published on 01 November 1997

Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells

scientific article published on 20 January 2016

Requirement of Zinc Transporter SLC39A7/ZIP7 for Dermal Development to Fine-Tune Endoplasmic Reticulum Function by Regulating Protein Disulfide Isomerase

scientific article published on 17 May 2017

Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis

scientific article published on 23 October 2017

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

article

Ring1A and Ring 1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells.

scientific article

Ring1B promotes hepatic stem/progenitor cell expansion through simultaneous suppression of Cdkn1a and Cdkn2a in mice

scientific article published in July 2014

Ring1a/b polycomb proteins regulate the mesenchymal stem cell niche in continuously growing incisors

scientific article published on 4 May 2012

Role of Polycomb RYBP in Maintaining the B-1-to-B-2 B-Cell Lineage Switch in Adult Hematopoiesis

scientific article published on 28 December 2015

Role of SOX17 in hematopoietic development from human embryonic stem cells

scientific article

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.

scientific article published on 4 October 2017

Role of a NK receptor, KLRE-1, in bone marrow allograft rejection: analysis with KLRE-1-deficient mice

scientific article

Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation

scientific article

Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation

scientific article published on 30 December 2014

S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance

scientific article

SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing

scientific article published on September 2013

SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes

scientific article

Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression

scientific article

Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity

scientific article published on 12 September 2017

Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks

scientific article published on 26 July 2010

Senescence marker protein-30 knockout mouse liver is highly susceptible to tumor necrosis factor-alpha- and Fas-mediated apoptosis

scientific journal article

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway

scientific article published on 01 November 2018

Stem Cell Epigenetics: Looking Forward

scientific article published on 01 June 2014

Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells.

scientific article

Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression.

scientific article published on 24 April 2019

TCR repertoire in early fetal mouse thymus

scientific article published in March 1995

Targeted disruption of dermatopontin causes abnormal collagen fibrillogenesis

scientific journal article

Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment.

scientific article

Tet DNA demethylase is required for plasma cell differentiation by controlling expression levels of IRF4

scientific article published on 25 June 2020

Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity

scientific article published on 22 June 2020

ThPOK represses CXXC5, which induces methylation of histone H3 lysine 9 in Cd40lg promoter by association with SUV39H1: implications in repression of CD40L expression in CD8+ cytotoxic T cells

scientific article

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.

scientific article

The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum

scientific article

The KDEL receptor modulates the endoplasmic reticulum stress response through mitogen-activated protein kinase signaling cascades

scientific article

The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

scientific article published on 11 November 2020

The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin.

scientific article published on September 2017

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

scientific journal article

The USP21 short variant (USP21SV) lacking NES, located mostly in the nucleus in vivo, activates transcription by deubiquitylating ubH2A in vitro

scientific article

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

article by Hiromitsu Hara et al published 7 May 2007 in Nature Immunology

The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

scientific article

The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression

scientific article published on 01 January 2002

The importance of disinfection therapy using povidone-iodine solution in atopic dermatitis

scientific article

The mouse Edr2 (Mph2) gene has two forms of mRNA encoding 90- and 36-kDa polypeptides

scientific journal article

The mouse YAF2 gene generates two distinct transcripts and is expressed in pre-and postimplantation embryos

scientific journal article

The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development.

scientific article published on 24 October 2014

The polycomb group protein SUZ12 regulates histone H3 lysine 9 methylation and HP1 alpha distribution.

scientific article published on 10 May 2007

The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells

scientific article

The role of Bcl6 in mature cardiac myocytes.

scientific article published in June 1999

The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors

scientific article published on 01 July 1997

The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways

scientific article

The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth

scientific article

Three developmental compartments involved in rib formation

scientific article

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

scientific article

Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation

scientific article published in June 2007

Type II membrane protein CD69 regulates the formation of resting T-helper memory

scientific article published on 2 April 2012

UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.

scientific article published on January 2013

Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex

scientific article published on 01 December 2018

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication

scientific article published on 8 September 2013

Unique composition of polycomb repressive complex 1 in hematopoietic stem cells

scientific article published in February 2007

V alpha 14+ NK T cells: a novel lymphoid cell lineage with regulatory function

scientific article published on 01 December 1996

Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes

scientific article published on 09 September 2021

Variant PRC1 competes with retinoic acid-related signals to repress Meis2 in the mouse distal forelimb bud

scientific article published on 11 October 2018

Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.

scientific article published on 22 May 2014

WIP1, a homeostatic regulator of the DNA damage response, is targeted by HIPK2 for phosphorylation and degradation

scientific article published on 18 July 2013

Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress.

scientific article

Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength

scientific journal article

Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development

scientific journal article

topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage

scientific article

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