Search filters

List of works by Garrett M Frampton

A pan-cancer landscape of telomeric content shows that RAD21 and HGF alterations are associated with longer telomeres

scientific article published on 26 February 2022

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

scientific article published on December 2008

An ErbB2 splice variant lacking exon 16 drives lung carcinoma

scientific article published on 29 July 2020

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial

scientific article

Characterization of 298 Patients with Lung Cancer Harboring MET Exon 14 Skipping Alterations.

scientific article published on 22 June 2016

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

scientific article

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

scientific article

Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer

scientific article published on 26 June 2019

Comprehensive Genomic Profiling Facilitates Implementation of the National Comprehensive Cancer Network Guidelines for Lung Cancer Biomarker Testing and Identifies Patients Who May Benefit From Enrollment in Mechanism-Driven Clinical Trials

scientific article published on 05 May 2016

Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization

scientific article published on 31 May 2016

Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers

scientific article published on 25 March 2022

Comprehensive genomic profiling of anal squamous cell carcinoma reveals distinct genomically defined classes

scientific article published on 6 April 2016

Concordance of genomic alterations between primary and recurrent breast cancer.

scientific article

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

scientific article (publication date: 8 August 2008)

CpG island structure and trithorax/polycomb chromatin domains in human cells

scientific article published on 20 July 2012

Densely interconnected transcriptional circuits control cell states in human hematopoiesis

scientific article

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

scientific article published on 13 May 2010

Differential gene expression in pulmonary artery endothelial cells exposed to sickle cell plasma

scientific article published in March 2005

Enhancer decommissioning by LSD1 during embryonic stem cell differentiation

scientific article

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

scientific article

GE-04COMPREHENSIVE GENOMIC PROFILING (CGP) OF PEDIATRIC GLIOMAS REVEALS A HIGH FREQUENCY OF CLINICALLY RELEVANT GENOMIC ALTERATIONS (CRGA) ASSOCIATED WITH BENEFIT FROM TARGETED THERAPY.

scientific article published on 21 April 2015

Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes

scientific article

Genomic Profiling of Prostate Cancers from Men with African and European Ancestry

scientific article published on 10 July 2020

High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers

scientific article published on 03 August 2020

Histone H3K27ac separates active from poised enhancers and predicts developmental state

scientific article

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

scientific article published on February 12, 2012

Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting

scientific article published on 10 March 2016

Microsatellite-Stable Tumors with High Mutational Burden Benefit from Immunotherapy

scientific article published on 12 August 2019

Mutations in the TERC template sequence can be incorporated into the telomeres of human tumors

Oncogenic alterations in ERBB2/HER2 represent potential therapeutic targets across tumors from diverse anatomic sites of origin

scientific article

Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias.

scientific article published on July 2016

Reliability and reproducibility of gene expression measurements using amplified RNA from laser-microdissected primary breast tissue with oligonucleotide arrays

scientific article published in February 2005

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

scientific article

SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state

scientific article

Somatic HLA class I loss is a widespread mechanism of immune evasion which refines the use of tumor mutational burden as a biomarker of checkpoint inhibitor response

scientific article published on 30 October 2020

Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade

scientific article published on 26 September 2016

Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity

scientific article published on 05 September 2012

The Genomic Landscape of Merkel Cell Carcinoma and Clinicogenomic Biomarkers of Response to Immune Checkpoint Inhibitor Therapy

scientific article published on 09 August 2019

The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors

scientific article published on 06 May 2020

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.

scientific article published on January 2010