List of works by Christopher J. Lengner

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

scientific article published on July 2008

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

scientific article (publication date: August 2014)

Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton

scientific article published in June 2002

An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.

scientific article published on 10 November 2003

Analysis of in vivo gene expression using epitope-tagged proteins

scientific article published on 01 January 2004

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

scientific article published in Journal of Biological Chemistry

Chromatin immunoprecipitation

scientific article published on 01 January 2004

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function

scientific article

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

scientific article published on 13 May 2010

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Direct cell reprogramming is a stochastic process amenable to acceleration

scientific article

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

scientific article

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation

scientific article published on 01 November 2019

Dll1<sup>+</sup> quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway

scientific article published on 18 January 2021

Electromagnetic fields mediate efficient cell reprogramming into a pluripotent state.

scientific article published in October 2014

Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis Congenita

scientific article published on 17 August 2016

Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain

scientific article

Functional integration of dopaminergic neurons directly converted from mouse fibroblasts

scientific article published on 20 October 2011

GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

scientific article published on 13 May 2022

Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts

scientific article published on 6 June 2016

Homogeneous generation of iDA neurons with high similarity to bona fide DA neurons using a drug inducible system

scientific article published on 6 September 2015

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

scientific article

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

scientific article

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3

scientific article published in 2023

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

scientific article published on 22 February 2016

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

scholarly article by Jacob Hanna et al published August 2015 in Cell Stem Cell

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

scholarly article by Jacob Hanna et al published May 2015 in Cell Stem Cell

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

Metastable pluripotent states in NOD-mouse-derived ESCs

scientific article

Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells

scientific article

Msi RNA-binding proteins control reserve intestinal stem cell quiescence.

scientific article published on 31 October 2016

Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins

scientific article

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

scientific article

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

scientific article published on 06 January 2014

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

scientific article

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program

scientific article

Networks and hubs for the transcriptional control of osteoblastogenesis.

scientific article published on June 2006

Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation

scientific journal article

Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis.

scientific article published on 6 July 2016

Oct4 expression is not required for mouse somatic stem cell self-renewal

scientific article

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish

scientific article published on 02 October 2013

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

scientific article

Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22.

scientific article published on 28 May 2015

Primary mouse embryonic fibroblasts: A model of mesenchymal cartilage formation

article

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

scientific article published on January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

scientific article published on 01 January 2004

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

scientific article

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

scientific article

Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

scientific article

Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation

scientific article

Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation.

scientific article published in July 2006

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

scientific article

Single-cell analysis of proxy reporter allele-marked epithelial cells establishes intestinal stem cell hierarchy

scientific article

The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins

scientific article published on 07 December 2015

Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.

scientific article

Transgenic mice with defined combinations of drug-inducible reprogramming factors

scientific article published on 18 January 2009

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium

scientific article

iPS cell technology in regenerative medicine

scientific article published on March 2010

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