List of works - Masato Koike

Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1

scientific article

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions

scientific journal article

LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis

article published in the Proceedings of the National Academy of Sciences of the United States of America

Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth

scientific article published on August 2006

Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6.

scientific article

RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway

scientific article

Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.

scientific article published in February 2008

Exendin-4 improves β-cell function in autophagy-deficient β-cells

scientific journal article

Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein

scientific article (publication date: April 2015)

NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization

scientific article published on 25 February 2014

Autophagic neuron death

scientific article published in January 2009

L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain

scientific article

Generation of a recombinant Oka varicella vaccine expressing mumps virus hemagglutinin-neuraminidase protein as a polyvalent live vaccine.

scientific article published on 5 November 2007

Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils

scientific article published in January 2015

Specific localization of lysosomal aminopeptidases in type II alveolar epithelial cells of the rat lung

scientific article

Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD.

scientific article published on 28 January 2016

Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains

scientific article

Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice

scientific article published on 05 August 2011

Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system

scientific article published on 20 December 2012

Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis

scholarly article by Yusuke Osonoi published in January 2018

Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice

scientific article published on 20 July 2016

The expression of tripeptidyl peptidase I in various tissues of rats and mice

scientific article published in August 2002

Lysosomal Storage of Subunit c of Mitochondrial ATP Synthase in Brain-Specific Atp13a2-Deficient Mice

scientific article published on 19 October 2016

Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain

scientific article published on 23 February 2017

Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats

scientific article published on February 2009

VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process

scientific article

Biogenesis and proteolytic processing of lysosomal DNase II

scientific article

The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress

scientific article published on 29 January 2016

Differential remodelling of peroxisome function underpins the environmental and metabolic adaptability of diplonemids and kinetoplastids

scientific article

Morphological process of podocyte development revealed by block-face scanning electron microscopy

scientific article

Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2.

scientific article published on 16 October 2017

Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons

scientific article

Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization

scientific article published on 19 March 2010

Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7.

scientific article published on 11 May 2017

Inefficient phagosome maturation in infant macrophages

scientific article published on 08 August 2008

Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions

scientific article published on 9 November 2012

Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS

scientific article published on 30 September 2016

Ablation of Csk in neural crest lineages causes corneal anomaly by deregulating collagen fibril organization and cell motility

scientific article

TDP-43 accelerates age-dependent degeneration of interneurons

scientific article

Possible involvement of iron-induced oxidative insults in neurodegeneration.

scientific article published on 27 December 2014

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes.

scientific article published on 22 March 2018

Cellular localization and tissue distribution of endogenous DFCP1 protein

scientific article

Suppression of Ischemia-Induced Hippocampal Pyramidal Neuron Death by Hyaluronan Tetrasaccharide through Inhibition of Toll-Like Receptor 2 Signaling Pathway

scientific article published on 11 June 2016

Different distribution patterns of the two mannose 6-phosphate receptors in rat liver.

scientific article published in November 2001

Nitric oxide-mediated injury of interstitial cells of Cajal and intestinal dysmotility under endotoxemia of mice

article

Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D-deficient mice.

scientific article published on 30 June 2005

Purification, cDNA cloning, and secretory properties of FLRG protein from PC12 cells and the distribution of FLRG mRNA and protein in rat tissues

scientific journal article

Human Herpesvirus 6A U14 Is Important for Virus Maturation

scientific article published on 11 November 2015

A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5

article

NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system

scientific article published on 09 January 2020

List of works by Masato Koike

Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions

LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis

Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth

Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6.

RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway

Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.

Exendin-4 improves β-cell function in autophagy-deficient β-cells

Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein

NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization

Autophagic neuron death

L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain

Generation of a recombinant Oka varicella vaccine expressing mumps virus hemagglutinin-neuraminidase protein as a polyvalent live vaccine.

Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils

Specific localization of lysosomal aminopeptidases in type II alveolar epithelial cells of the rat lung

Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD.

Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains

Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice

Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system

Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis

Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice

The expression of tripeptidyl peptidase I in various tissues of rats and mice

Lysosomal Storage of Subunit c of Mitochondrial ATP Synthase in Brain-Specific Atp13a2-Deficient Mice

Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain

Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats

VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process

Biogenesis and proteolytic processing of lysosomal DNase II

The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress

Differential remodelling of peroxisome function underpins the environmental and metabolic adaptability of diplonemids and kinetoplastids

Morphological process of podocyte development revealed by block-face scanning electron microscopy

Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2.

Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons

Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization

Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7.

Inefficient phagosome maturation in infant macrophages

Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions

Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS

Ablation of Csk in neural crest lineages causes corneal anomaly by deregulating collagen fibril organization and cell motility

TDP-43 accelerates age-dependent degeneration of interneurons

Possible involvement of iron-induced oxidative insults in neurodegeneration.

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes.

Cellular localization and tissue distribution of endogenous DFCP1 protein

Suppression of Ischemia-Induced Hippocampal Pyramidal Neuron Death by Hyaluronan Tetrasaccharide through Inhibition of Toll-Like Receptor 2 Signaling Pathway

Different distribution patterns of the two mannose 6-phosphate receptors in rat liver.

Nitric oxide-mediated injury of interstitial cells of Cajal and intestinal dysmotility under endotoxemia of mice

Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D-deficient mice.

Purification, cDNA cloning, and secretory properties of FLRG protein from PC12 cells and the distribution of FLRG mRNA and protein in rat tissues

Human Herpesvirus 6A U14 Is Important for Virus Maturation

A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5

NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system