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List of works by Frank Edenhofer

A LewisX glycoprotein screen identifies the low density lipoprotein receptor-related protein 1 (LRP1) as a modulator of oligodendrogenesis in mice.

scientific article published on 24 April 2013

A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire.

scientific article published on 30 November 2017

A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells

scientific article

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

scientific article

Abrogation of Gap Junctional Communication in ES Cells Results in a Disruption of Primitive Endoderm Formation in Embryoid Bodies.

scientific article published on 21 November 2016

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients

scientific article published on 27 April 2021

Automated selection and harvesting of pluripotent stem cell colonies

scientific article published on March 2012

BMP/SMAD pathway promotes neurogenesis of midbrain dopaminergic neurons in vivo and in human induced pluripotent and neural stem cells

scientific article published on 10 January 2018

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain.

scientific article published on 26 September 2017

Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells

scientific article published in September 2006

Cell-permeant recombinant Nanog protein promotes pluripotency by inhibiting endodermal specification.

scientific article published on 5 March 2014

Cellular reprogramming employing recombinant sox2 protein

scientific article published on 29 May 2012

Characterization of a novel cell penetrating peptide derived from human Oct4.

scientific article

Conditional mutagenesis by cell-permeable proteins: potential, limitations and prospects

scientific article published on January 2007

Deciphering the stem cell machinery as a basis for understanding the molecular mechanism underlying reprogramming

scientific article published on 07 August 2009

Derivation of Adult Human Fibroblasts and their Direct Conversion into Expandable Neural Progenitor Cells

scientific article

Direct conversion of fibroblasts into stably expandable neural stem cells

scientific article

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

scientific article

Efficient in vitro and in vivo excision of floxed sequences with a high-capacity adenoviral vector expressing Cre recombinase

scientific article published on July 2002

Engineering cell-permeable protein

scientific article published on 28 December 2009

Engineering cell-permeant FLP recombinase for tightly controlled inducible and reversible overexpression in embryonic stem cells

scientific article published on May 2010

Enhanced purification of cell-permeant Cre and germline transmission after transduction into mouse embryonic stem cells

scientific article published in August 2007

Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.

scientific article published on 22 March 2017

Excision of viral reprogramming cassettes by Cre protein transduction enables rapid, robust and efficient derivation of transgene-free human induced pluripotent stem cells

scientific article

Exploring refined conditions for reprogramming cells by recombinant Oct4 protein

scientific article published in January 2010

Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells

scientific article published on 01 August 2018

Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3.

scientific article published on 13 February 2018

Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene

scientific article published on 10 August 2018

Generation of transducible versions of transcription factors Oct4 and Sox2.

scientific article

Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy

scientific article published on 02 February 2019

Genetic engineering of mammalian cells by direct delivery of FLP recombinase protein

scientific article published on 23 December 2010

Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells

scholarly article by Marc Christian Thier et al published 3 January 2019 in Cell Stem Cell

Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1.

scientific article published on 17 June 2009

Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo.

scientific article published on May 2010

Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.

scientific article published on 3 June 2016

Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation.

scientific article

Merging fields: stem cells in neurogenesis, transplantation, and disease modeling

scientific article published on April 2006

Metabolic substrate shift in human induced pluripotent stem cells during cardiac differentiation: Functional assessment using in vitro radionuclide uptake assay

scientific article published on 21 June 2018

MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells

scientific journal article

Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile

scientific article published on 01 May 2018

Model Testing of PluriTest with Next-Generation Sequencing Data

scientific article

Monodispersity of recombinant Cre recombinase correlates with its effectiveness in vivo

scientific article

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause

scientific article published on February 2016

Nanog induces suppression of senescence through downregulation of p27KIP1 expression

scientific article published on 21 January 2016

Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

scientific article published in Scientific Reports

New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility

scientific article published on May 2001

Next-generation disease modeling with direct conversion: a new path to old neurons

scientific article published on 26 November 2019

Non-genetic modulation of Notch activity by artificial delivery of Notch intracellular domain into neural stem cells

scientific article published on September 2012

Novel reporter mouse reveals constitutive and inflammatory expression of IFN-beta in vivo

scientific article

Overexpression of active Syrian golden hamster prion protein PrPc as a glutathione S-transferase fusion in heterologous systems.

scientific article published on August 1995

Partial Dedifferentiation of Murine Radial Glia-Type Neural Stem Cells by Brn2 and c-Myc Yields Early Neuroepithelial Progenitors.

scientific article published on 7 November 2015

Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage

scientific article

Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy

scientific article published on 01 February 2007

Prion protein PrPc interacts with molecular chaperones of the Hsp60 family

scientific article published in July 1996

Protein transduction revisited: novel insights into the mechanism underlying intracellular delivery of proteins

scientific article published on January 2008

Quantification of cell fusion events human breast cancer cells and breast epithelial cells using a Cre-LoxP-based double fluorescence reporter system

scientific article

Recombinant prion protein rPrP27-30 from Syrian golden hamster reveals proteinase K sensitivity

scientific article published on February 1996

Roadmap to cellular reprogramming--manipulating transcriptional networks with DNA, RNA, proteins and small molecules.

scientific article published on June 2013

Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling

scientific article

Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver

scientific journal article

Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single-use bioreactors.

scientific article published on 6 April 2017

Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase

scientific article published in June 2006

Sox2 is essential for formation of trophectoderm in the preimplantation embryo

scientific article

Stage-specific conditional mutagenesis in mouse embryonic stem cell-derived neural cells and postmitotic neurons by direct delivery of biologically active Cre recombinase

scientific article published on 7 September 2006

Stem cell engineering using transducible Cre recombinase

scientific article published in January 2007

Take the shortcut - direct conversion of somatic cells into induced neural stem cells and their biomedical applications

scientific article published on 01 December 2019

The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells

scientific article

The promise of genetic screens in human <i>in vitro</i> brain models

scientific article published in 2023

The vascular adventitia: An endogenous, omnipresent source of stem cells in the body

scientific article

Transcription factor-based modulation of neural stem cell differentiation using direct protein transduction

scientific article

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

scientific article

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