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List of works by Stefan Gerhardt

4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1)

scientific article

4-Acyl pyrroles: mimicking acetylated lysines in histone code reading

scientific article

A Conformational Switch Triggers Nitrogenase Protection from Oxygen Damage by Shethna Protein II (FeSII)

scientific article

A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions ⬇️

scientific article published on September 24, 2010

A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I.

scientific article

Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study

scientific article

Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation

scientific article

Biocatalytic Properties and Structural Analysis of Phloroglucinol Reductases.

scientific article published on 22 November 2016

Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe

scientific article published in January 2002

Crystal structure of Cdc11, a septin subunit from Saccharomyces cerevisiae

scientific article

Crystal structure of an archaeal pentameric riboflavin synthase in complex with a substrate analog inhibitor: stereochemical implications

scientific article published on 4 November 2005

Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis

scientific article

Design, synthesis, and evaluation of 6-carboxyalkyl and 6-phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase

scientific article published in August 2002

Deterministic generation of bright single resonance fluorescence photons from a Purcell-enhanced quantum dot-micropillar system ⬇️

scientific article published in December 2015

Dipeptidyl nitrile inhibitors of Cathepsin L

scientific article

Discovery of a Potent, Selective, and Orally Bioavailable Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor: Discovery of 2-[(3S)-1-[5-(Cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic Acid (AZD4017) ⬇️

scientific article published on June 19, 2012

Engineering a High-Affinity Anti-IL-15 Antibody: Crystal Structure Reveals an α-Helix in VH CDR3 as Key Component of Paratope ⬇️

scientific article published on December 16, 2010

Highly indistinguishable on-demand resonance fluorescence photons from a deterministic quantum dot micropillar device with 74% extraction efficiency ⬇️

scientific article published in April 2016

Improving coiled coil stability while maintaining specificity by a bacterial hitchhiker selection system

scientific article

Incorporation of an amide into 5-phosphonoalkyl-6-D-ribitylaminopyrimidinedione lumazine synthase inhibitors results in an unexpected reversal of selectivity for riboflavin synthase vs lumazine synthase

scientific article published in October 2002

Lead optimisation of selective non-zinc binding inhibitors of MMP13. Part 2

scientific article

MacA is a Second Cytochrome c Peroxidase of Geobacter sulfurreducens

scientific article

Novel Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor with Reduced Acyl Glucuronide Liability: The Discovery of 4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic Acid (AZD8329) ⬇️

scientific article published on November 7, 2012

Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes.

scientific article

Prevention of MKK6-dependent activation by binding to p38alpha MAP kinase

scientific article

Quantum dot-micropillars: A bright source of coherent single photons

Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments

scientific article

Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking

scientific article

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.

scientific article

Selective non zinc binding inhibitors of MMP13

scientific article

Structural and functional characterisation of the methionine adenosyltransferase from Thermococcus kodakarensis

scientific article

Structural and functional characterization of 4-hydroxyphenylpyruvate dioxygenase from the thermoacidophilic archaeon Picrophilus torridus.

scientific article published on 3 May 2014

Structural basis of the action of glucosyltransferase Lgt1 from Legionella pneumophila

scientific article

Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2

scientific article published on 7 January 2015

Structure and Properties of an Engineered Transketolase from Maize

scientific article

Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids

scientific article

Structure of GlnK1, a signalling protein fromArchaeoglobus fulgidus ⬇️

scientific article published on January 21, 2011

Structure-Based Development of an Affinity Probe for Sirtuin 2

scientific article

Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazine

scientific article

The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis

scientific article

The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases

scientific article

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